Is it in our genes? The structure of our brains? Our genome may determine our eye color and even aspects of our personality. But our friendships, failures, and passions also shape who we are. The question is: how?Sebastian Seung, a dynamic professor at MIT, is on a quest to discover the biological basis of identity. He believes it lies in the pattern of connections between the brain’s neurons, which change slowly over time as we learn and grow. The connectome, as it’s called, is where our genetic inheritance intersects with our life experience. It’s where nature meets nurture.Seung introduces us to the dedicated researchers who are mapping the brain’s connections, neuron by neuron, synapse by synapse. It is a monumental undertaking—the scientific equivalent of climbing Mount Everest—but if they succeed, it could reveal the basis of personality, intelligence, memory, and perhaps even mental disorders. Many scientists speculate that people with anorexia, autism, and schizophrenia are "wired differently," but nobody knows for sure. The brain’s wiring has never been clearly seen.In sparklingly clear prose, Seung reveals the amazing technological advances that will soon help us map connectomes. He also examines the evidence that these maps will someday allow humans to "upload" their minds into computers, achieving a kind of immortality.Connectome is a mind-bending adventure story, told with great passion and authority. It presents a daring scientific and technological vision for at last understanding what makes us who we are. Welcome to the future of neuroscience.

    It makes us question ourselves and our decisions, causes us to worry about the future, and fills our days with dread and emotional turbulence. Based in acceptance and commitment therapy (ACT) and cognitive behavioral therapy (CBT), this book is designed to help you break the cycle of worry.Worry convinces us there's danger, and then tricks us into getting into fight, flight, or freeze mode—even when there is no danger. The techniques in this book, rather than encouraging you to avoid or try to resist anxiety, shows you how to see the trick that underlies your anxious thoughts, and how avoidance can backfire and make anxiety worse.If you’re ready to start observing your anxious feelings with distance and clarity—rather than getting tricked once again—this book will show you how.

    Artfully crafted and told with warmth and honesty, this is the story of Linda’s journey, interwoven with insights into her patients’ diverse experiences of depression -inextricably linked with problems in the past and the present such as vulnerability, fear, loss, loneliness, dependence and grief.  She sets out to convey, in a new and original way, how it truly feels to experience this devastating illness, what psychotherapy is about, and the role of medication—and provides hope for those who suffer from depression and their loved ones while busting the stigma of mental illness.

    Plagued with fear that her friends and family will be taken from her if she's not watching--that her mother will die, or forget she has children and just move away--Stern treats every parting as her last. Shuttled between a barefoot bohemian life with her mother in Greenwich Village, and a sanitized, stricter world of affluence uptown with her father, Stern has little she can depend on. And when Etan Patz disappears down the block from their MacDougal Street home, she can't help but believe that all her worst fears are about to come true. Tenderly delivered and expertly structured, Stern's memoir is a document of the transformation of New York City and a deep, personal, and comedic account of the trials and errors of seeing life through a very unusual lens.

    Scientists have long supported this assumption by claiming that emotions are hardwired in the body or the brain. Today, however, the science of emotion is in the midst of a revolution on par with the discovery of relativity in physics and natural selection in biology—ans this paradigm shift has far-reaching implications for us all.Leading the charge is psychologist and neuroscientist Lisa Feldman Barrett, whose theory of emotion is driving a deeper understanding of the mind and brain, and shedding new light on what it means to be human. Her research overturns the widely held belief that emotions are housed in different parts of the brain and are universally expressed and recognized. Instead, she has shown that emotion is constructed in the moment, by core systems that interact across the whole brain, aided by a lifetime of learning. This new theory means that you play a much greater role in your emotional life than you ever thought. Its repercussions are already shaking the foundations not only of psychology but also of medicine, the legal system, child-rearing, meditation, and even airport security.Why do emotions feel automatic? Does rational thought really control emotion? How does emotion affect disease? How can you make your children more emotionally intelligent? How Emotions Are Made answers these questions and many more, revealing the latest research and intriguing practical applications of the new science of emotion, mind, and brain.

    The Other Brain is the story of glia, which make up approximately 85 percent of the cells in the brain. Long neglected as little more than cerebral packing material ("glia" means glue), glia are sparking a revolution in brain science.Glia are completely different from neurons, the brain cells that we are familiar with. Scientists are discovering that glia have their own communication network, which operates in parallel to the more familiar communication among neurons. Glia provide the insulation for the neurons, and glia even regulate the flow of information between neurons.But it is the potential breakthroughs for medical science that are the most exciting frontier in glia research today. Diseases such as brain cancer and multiple sclerosis are caused by diseased glia. Glia are now believed to play an important role in such psychiatric illnesses as schizophrenia and depression, and in neurodegenerative diseases such as Parkinson's and Alzheimer's. They are linked to infectious diseases such as HIV and prion disease (mad cow disease, for example) and to chronic pain. Scientists have discovered that glia repair the brain and spinal cord after injury and stroke. The more we learn about these cells that make up the "other" brain, the more important they seem to be.Written by a neuroscientist who is a leader in the research to reveal the secrets of these brain cells, The Other Brain offers a firsthand account of science in action. It takes us into the laboratories where important discoveries are being made, and it explains how scientists are learning that glial cells come in different types, with different capabilities. It tells the story of glia research from its origins to the most recent discoveries and gives readers a much more complete understanding of how the brain works and where the next breakthroughs in brain science and medicine are likely to come.

    She also lectures widely on autism—because Temple Grandin is autistic, a woman who thinks, feels, and experiences the world in ways that are incomprehensible to the rest of us. In this unprecedented book, Grandin delivers a report from the country of autism. Writing from the dual perspectives of a scientist and an autistic person, she tells us how that country is experienced by its inhabitants and how she managed to breach its boundaries to function in the outside world. What emerges in Thinking in Pictures is the document of an extraordinary human being, one who, in gracefully and lucidly bridging the gulf between her condition and our own, sheds light on the riddle of our common identity.

    Beginning with the simplest breathing and sitting techniques, and based on three key skills—concentration, mindfulness, and lovingkindness—it’s a practice anyone can do and that can transform our lives by bringing us greater resiliency, creativity, peace, clarity, and balance. This updated 10th anniversary edition includes exercises, journal prompts, and ten guided meditations available for download online and through scannable QR codes.

    Laing explains how we all exist in the world as beings, defined by others who carry a model of us in their heads, just as we carry models of them in our heads. In later writings he often takes this to deeper levels, laboriously spelling out how "A knows that B knows that A knows that B knows..."! Our feelings and motivations derive very much from this condition of "being in the world" in the sense of existing for others, who exist for us. Without this we suffer "ontological insecurity", a condition often expressed in terms of "being dead" by people who are clearly still physically alive.This watershed work aimed to make madness comprehensible, and in doing so revolutionized the way we perceive mental illness. Using case studies of patients he had worked with, psychiatrist R. D. Laing argued that psychosis is not a medical condition, but an outcome of the 'divided self', or the tension between the two personas within us: one our authentic, private identity, and the other the false, 'sane' self that we present to the world. Laing's radical approach to insanity offered a rich existential analysis of personal alienation and made him a cult figure in the 1960s, yet his work was most significant for its humane attitude, which put the patient back at the centre of treatment. R.D. Laing (1927-1989), one of the best-known psychiatrists of modern times, was born in Glasgow, Scotland.This work is available on its own or as part of the 7 volume set iSelected Works of R. D. Laing

    When a small vial arrives in her mailbox from "Lewis Carroll," Ayelet Waldman is at a low point. Her mood storms have become intolerably severe; she has tried nearly every medication possible; her husband and children are suffering with her. So she opens the vial, places two drops on her tongue, and joins the ranks of an underground but increasingly vocal group of scientists and civilians successfully using therapeutic microdoses of LSD. As Waldman charts her experience over the course of a month--bursts of productivity, sleepless nights, a newfound sense of equanimity--she also explores the history and mythology of LSD, the cutting-edge research into the drug, and the byzantine policies that control it. Drawing on her experience as a federal public defender, and as the mother of teenagers, and her research into the therapeutic value of psychedelics, Waldman has produced a book that is eye-opening, often hilarious, and utterly enthralling.

    A lifelong nonbeliever, he found himself on a bizarre adventure, involving a disgraced pastor, a mysterious self-help guru, and a gaggle of brain scientists. Eventually, Harris realized that the source of his problems was the very thing he always thought was his greatest asset: the incessant, insatiable voice in his head, which had both propelled him through the ranks of a hyper-competitive business and also led him to make the profoundly stupid decisions that provoked his on-air freak-out.We all have a voice in our head. It’s what has us losing our temper unnecessarily, checking our email compulsively, eating when we’re not hungry, and fixating on the past and the future at the expense of the present. Most of us would assume we’re stuck with this voice – that there’s nothing we can do to rein it in – but Harris stumbled upon an effective way to do just that. It’s a far cry from the miracle cures peddled by the self-help swamis he met; instead, it’s something he always assumed to be either impossible or useless: meditation. After learning about research that suggests meditation can do everything from lower your blood pressure to essentially rewire your brain, Harris took a deep dive into the underreported world of CEOs, scientists, and even marines who are now using it for increased calm, focus, and happiness.10% Happier takes readers on a ride from the outer reaches of neuroscience to the inner sanctum of network news to the bizarre fringes of America’s spiritual scene, and leaves them with a takeaway that could actually change their lives.

    After World War II, Don's work with the Air Force brought them to Colorado, where their twelve children perfectly spanned the baby boom: the oldest born in 1945, the youngest in 1965. In those years, there was an established script for a family like the Galvins—aspiration, hard work, upward mobility, domestic harmony—and they worked hard to play their parts. But behind the scenes was a different story: psychological breakdown, sudden shocking violence, hidden abuse. By the mid-1970s, six of the ten Galvin boys, one after another, were diagnosed as schizophrenic. How could all this happen to one family?What took place inside the house on Hidden Valley Road was so extraordinary that the Galvins became one of the first families to be studied by the National Institute of Mental Health. Their story offers a shadow history of the science of schizophrenia, from the era of institutionalization, lobotomy, and the schizophrenogenic mother to the search for genetic markers for the disease, always amid profound disagreements about the nature of the illness itself. And unbeknownst to the Galvins, samples of their DNA informed decades of genetic research that continues today, offering paths to treatment, prediction, and even eradication of the disease for future generations.With clarity and compassion, bestselling and award-winning author Robert Kolker uncovers one family's unforgettable legacy of suffering, love, and hope.

    Each page offers simple activities that help you understand the roles of your “happy chemicals”—serotonin, dopamine, oxytocin, and endorphin. You’ll also learn how to build new habits by rerouting the electricity in your brain to flow down a new pathway, making it even easier to trigger these happy chemicals and increase feelings of satisfaction when you need them most. Filled with dozens of exercises that will help you reprogram your brain, Habits of a Happy Brain shows you how to live a happier, healthier life!

    My heart beats too fast. My hands tremble and sweat. I feel like there's a weight on my chest. My stomach churns. I have terrible headaches. I can't sleep. Sometimes I can't even leave my house...These common symptoms of anxiety are "minor" only to the people who don't suffer from them. But to the millions they affect, these problems make the difference between a happy, healthy life and one of crippling fear and frustration.In Hope and Help for Your Nerves, Dr. Claire Weekes offers the results of years of experience treating real patients--including some who thought they'd never recover. With her simple, step-by-step guidance, you will learn how to understand and analyze your own symptoms of anxiety and find the power to conquer your fears for good.

    Her journey there began when, overwhelmed by anxiety as she completed her doctoral studies in London, England, she found relief by dosing herself with alcohol and tranquillizers. She then embarked on what would turn out to be a decades- long psychoanalysis.The analysis dredged up acutely painful memories of an unhappy and confusing childhood back in Saskatoon. As Taylor struggled to cope with these, she would twice be re-admitted to Friern. She took refuge in day-care institutions and a psychiatric hostel, all the while continuing her therapy, which eventually put her on the road to recovery.This searingly honest, beautifully written memoir is the narrative of the author’s madness years, set inside the wider story of our treatment of psychiatric illness: from the great age of asylums to the current era of community care, ‘Big Pharma’, and quick fixes. It is a meditation on her own experience as well as that of millions of others – both in Europe and in North America – who have suffered, are suffering, and will suffer from mental illness.