After days of treatment for recurring infection, it becomes obvious that her arm must be amputated. Dr. Ajay Seth, the son of immigrant parents from India and a local orthopaedic surgeon in private practice, performs his first-ever amputation procedure. In the months that follow, divine intervention, combined with Melissa’s determination and Dr. Seth’s disciplined commitment and dedication to his patients, brings about the opportunity for a medical breakthrough that will potentially transform the lives of amputees around the world.Rewired is the inspirational, miraculous story of Dr. Seth’s revolutionary surgery that allows Melissa to not just move a prosthetic arm simply by thinking, but to actually feel with the prosthetic hand, just as she would with her natural arm. This resulted in what others have recognized as the world’s most advanced amputee, all done from Dr. Seth’s private practice in a community hospital, using a local staff, and with no special training or extensive research funding.

    Most of us appreciate that at some level. But what does it mean for us to have more in common with a horse and an elephant than we do with a parrot, snake or frog?After a misdirected football left new father Liam Drew clutching a uniquely mammalian part of his anatomy, he decided to find out more. Considering himself as a mammal first and a human second, Liam delves into ancient biological history to understand what it means to be mammalian.In his humorous and engaging style, Liam explores the different characteristics that distinguish mammals from other types of animals. He charts the evolution of milk, warm blood and burgeoning brains, and examines the emergence of sophisticated teeth, exquisite ears, and elaborate reproductive biology, plus a host of other mammalian innovations. Entwined are tales of zoological peculiarities and reflections on how being a mammal has shaped the author's life.I, Mammal is a history of mammals and their ancestors and of how science came to grasp mammalian evolution. And in celebrating our mammalian-ness, Liam Drew binds us a little more tightly to the five and a half thousand other species of mammal on this planet and reveals the deep roots of many traits humans hold dear.

    Now he gathers the best of his best, updated and expanded upon, to guide readers on a mind-bending tour of the far frontier, and how these advances are radically transforming our lives. From the ways science and technology are fundamentally altering our bodies and our world (the world’s first bionic soldier, the future of evolution) to those explosive collisions between science and culture (life extension and bioweapons), we’re crossing moral and ethical lines we’ve never faced before.As Kotler writes, “Life is tricky sport—and that's the emotional core of this story, the real reason we can’t put Pandora back in the box. When you strip everything else away, technology is nothing more than the promise of an easier tomorrow. It’s the promise of hope. And how do you stop hope?”Join Kotler in this fascinating exploration of our incredible next: a deep dive into those future technologies happening now—and what it means to be a part of this brave new world.

    However, in a country of more than 325 million people, addressing everyone's issues is challenging. How can we effect beneficial change for everyone so we all can thrive? What is the great equalizer?In this book, Daniel E. Dawes argues that political determinants of health create the social drivers--including poor environmental conditions, inadequate transportation, unsafe neighborhoods, and lack of healthy food options--that affect all other dynamics of health. By understanding these determinants, their origins, and their impact on the equitable distribution of opportunities and resources, we will be better equipped to develop and implement actionable solutions to close the health gap.Dawes draws on his firsthand experience helping to shape major federal policies, including the Affordable Care Act, to describe the history of efforts to address the political determinants that have resulted in health inequities. Taking us further upstream to the underlying source of the causes of inequities, Dawes examines the political decisions that lead to our social conditions, makes the social determinants of health more accessible, and provides a playbook for how we can address them effectively. A thought-provoking and evocative account that considers both the policies we think of as health policy and those that we don't, The Political Determinants of Health provides a novel, multidisciplinary framework for addressing the systemic barriers preventing the United States from becoming the healthiest nation in the world.

    The discovery initiated Gessen into a club of sorts: the small (but exponentially expanding) group of people in possession of a new and different way of knowing themselves through what is inscribed in the strands of their DNA. As she wrestled with a wrenching personal decision—what to do with such knowledge—Gessen explored the landscape of this brave new world, speaking with others like her and with experts including medical researchers, historians, and religious thinkers. Blood Matters is a much-needed field guide to this unfamiliar and unsettling territory. It explores the way genetic information is shaping the decisions we make, not only about our physical and emotional health but about whom we marry, the children we bear, even the personality traits we long to have. And it helps us come to terms with the radical transformation that genetic information is engineering in our most basic sense of who we are and what we might become.

    If America could send a man to the moon, shouldn’t the best surgeons in the world be able to build an artificial heart? In Ticker, Texas Monthly executive editor and two time National Magazine Award winner Mimi Swartz shows just how complex and difficult it can be to replicate one of nature’s greatest creations. Part investigative journalism, part medical mystery, Ticker is a dazzling story of modern innovation, recounting fifty years of false starts, abysmal failures and miraculous triumphs, as experienced by one the world’s foremost heart surgeons, O.H. “Bud” Frazier, who has given his life to saving the un-savable. His journey takes him from a small town in west Texas to one of the country’s most prestigious medical institutions, The Texas Heart Institute, from the halls of Congress to the animal laboratories where calves are fitted with new heart designs. The roadblocks to success —medical setbacks, technological shortcomings, government regulations – are immense. Still, Bud and his associates persist, finding inspiration in the unlikeliest of places. A field beside the Nile irrigated by an Archimedes screw. A hardware store in Brisbane, Australia. A seedy bar on the wrong side of Houston. Until post WWII, heart surgery did not exist. Ticker provides a riveting history of the pioneers who gave their all to the courageous process of cutting into the only organ humans cannot live without. Heart surgeons Michael DeBakey and Denton Cooley, whose feud dominated the dramatic beginnings of heart surgery. Christian Barnaard, who changed the world overnight by performing the first heart transplant. Inventor Robert Jarvik, whose artificial heart made patient Barney Clark a worldwide symbol of both the brilliant promise of technology and the devastating evils of experimentation run amuck. Rich in supporting players, Ticker introduces us to Bud’s brilliant colleagues in his quixotic quest to develop an artificial heart: Billy Cohn, the heart surgeon and inventor who devotes his spare time to the pursuit of magic and music; Daniel Timms, the Brisbane biomedical engineer whose design of a lightweight, pulseless heart with but a single moving part offers a new way forward. And, as government money dries up, the unlikeliest of backers, Houston’s furniture king, Mattress Mack. In a sweeping narrative of one man’s obsession, Swartz raises some of the hardest questions of the human condition. What are the tradeoffs of medical progress? What is the cost, in suffering and resources, of offering patients a few more months, or years of life? Must science do harm to do good? Ticker takes us on an unforgettable journey into the power and mystery of the human heart.

    The Haywire Heart is the first book to examine heart conditions in athletes. Intended for anyone who competes in endurance sports like cycling, triathlon, running races of all distances, and cross-country skiing, The Haywire Heart presents the evidence that going too hard or too long can damage your heart forever. You’ll find what to watch out for, what to do about it, and how to protect your heart so you can enjoy the sports you love for years to come. The Haywire Heart shares the developing research into a group of conditions known as “athlete’s heart”, starting with a wide-ranging look at the warning signs, symptoms, and how to recognize your potential risk. Leading cardiac electrophysiologist and masters athlete Dr. John Mandrola explores the prevention and treatment of heart conditions in athletes like arrhythmia, atrial fibrillation and flutter, tachycardia, hypertrophy, and coronary artery disease. He reviews new research about exercise intensity and duration, recovery, inflammation and calcification, and the ways athletes inflict lasting harm. These heart problems are appearing with alarming frequency among masters athletes who are pushing their bodies harder than ever in the hope that exercise will keep them healthy and strong into their senior years. The book is complete with gripping case studies of elite and age-group athletes from journalist Chris Case—like the scary condition that nearly killed cyclist and coauthor Lennard Zinn—and includes a frank discussion of exercise addiction and the mental habits that prevent athletes from seeking medical help when they need it.Dr. Mandrola explains why many doctors misdiagnose heart conditions in athletes and offers an invaluable guide on how to talk with your doctor about your condition and its proven treatments. He covers known heart irritants, training and rest modifications, effective medicines, and safe supplements that can reduce the likelihood of heart damage from exercise. Heart conditions affect hardcore athletes as well as those who take up sports seeking better health and weight loss. The Haywire Heart is a groundbreaking and critically important guide to heart care for athletes. By protecting your heart now and watching for the warning signs, you can avoid crippling heart conditions and continue to exercise and compete for years to come.

    But what if a respected scientist challenged them to make contact with the beyond under controlled laboratory conditions? What if the results not only stunned a skeptical scientist but also offered astonishing answers to a timeless question: Is there life after death? THE AFTERLIFE EXPERIMENTS Risking his academic reputation, Dr. Gary E. Schwartz asked well-known mediums to become part of a series of experiments to prove, or disprove, the existence of an afterlife. This riveting narrative, with electrifying transcripts, documents stringently monitored experiments in which mediums attempted to contact dead friends and relatives of "sitters" who were masked from view and never spoke, depriving the mediums of any cues. Here are the results that awed sitters and researchers alike: a revelation about a son's suicide, what a deceased father wanted to say about his last days in a coma, the transformation of a man's lifelong doubts about the afterlife, and, most amazing of all, a forecast of a beloved spouse's death. Forced by data to abandon skepticism, Schwartz presents this amazing account of his groundbreaking work, compelling from first page to last.

    Twenty-four true, wide-ranging tales of crime, history, human behavior, illness, and ethics, told from the personal perspective of the author, an eminent physician-lawyer who uses the stories to illustrate the principles of human genetics and to discuss the broader issues.

    Will our species change radically? Or will we become builders of the next dominant intelligence on Earth- the machine?These and other seemingly fantastic scenarios are the very possible realities explored in Peter Ward's Future Evolution, a penetrating look at what might come next in the history of the planet. Looking to the past for clues about the future, Ward describes how the main catalyst for evolutionary change has historically been mass extinction. While many scientist direly predict that humanity will eventually create such a situation, Ward argues that one is already well underway--the extinction of large mammals--and that a new Age of Humanity is coming that will radically revise the diversity of life on Earth. Finally, Ward examines the question of human extinction and reaches the startling conclusion that the likeliest scenario is not our imminent demise but long term survival--perhaps reaching as far as the death of the Sun!Full of Alexis Rockman's breathtaking color images of what animals, plants and other organisms might look like thousands and millions of years from now, Future Evolution takes readers on an incredible journey through time from the deep past into the far future.

    We’ll look at what identical twins can teach us about the epigenetic effects of our environment and experiences, why certain genes are 'switched on' or off at various stages of embryonic development, and how scientists have reversed the specialization of cells to clone frogs from a single gut cell. In Introducing Epigenetics, Cath Ennis and Oliver Pugh pull apart the double helix, examining how the epigenetic building blocks and messengers that interpret and edit our genes help to make us, well, us.

    In The Rebirth of Nature, Sheldrake urges us to move beyond the centuries-old mechanistic view of nature, explaining why we can no longer regard the world as inanimate and purposeless. Sheldrake shows how recent developments in science itself have brought us to the threshold of a new synthesis in which traditional wisdom, intuitive experience, and scientific insight can be mutually enriching.

    With this book, discover how to get the best sound for your money, how to identify the weak links in your system and upgrade where it will do the most good, how to set up and tweak your system for maximum performance, and how to become a more perceptive and appreciative listener. Just a few of the secrets you will learn cover high-end sound on a budget, how to do it cheap and still do it right; five system set-up mistakes and how to avoid them; how to make your speakers sound up to 50% better, at no cost; how to choose and set up a computer-based music system; how to find the one speaker in 50 worth owning; and why all 100-watt amplifiers don't sound the same. Since the first edition's publication in 1994, The Complete Guide to High-End Audio has been considered the essential reference on high-quality music reproduction, with more than 150,000 copies sold in five languages.

    Natalie Angier probes the origins of language, Paul Raffaele describes a remote Amazonian tribe untouched by the modern world, and Frans B. M. de Waal explains what a new breed of economists is learning from monkeys. Drake Bennett profiles the creator of Ecstasy and more than two hundred other psychedelic compounds -- a man hailed by some as one of the twentieth century's most important scientists.Some of the selections reflect the news of the past year. Daniel C. Dennett questions the debate over intelligent design -- is evolution just a theory? --while Chris Mooney reports on how this debate almost tore one small town apart. John Hockenberry examines how blogs are transforming the twenty-first-century battlefield, Larry Cahill probes the new science uncovering male and female brain differences, Daniel Roth explains why the programmer who made it easy to pirate movies over the Internet is now being courted by Hollywood, and Charles C. Mann looks at the dark side of increased human life expectancy.Reaching out beyond our own planet, Juan Maldacena questions whether we actually live in a three-dimensional world and whether gravity truly exists. Dennis Overbye surveys the continuing scientific mystery of time travel, and Robert Kunzig describes new x-ray images of the heavens, including black holes, exploding stars, colliding galaxies, and other wonders the eye can't see.

    New BIG IDEAs help all students focus on the most important concepts. Students explore concepts through engaging narrative, frequent use of analogies, familiar examples, and clear and instructional graphics. Now, with Success Tracker™ online, teachers can choose from a variety of diagnostic and benchmark tests to gauge student comprehension. Targeted remediation is available too! Whether using the text alone or in tandem with exceptional ancillaries and technology, teachers can meet the needs of every student at every learning level.With unparalleled reading support, resources to reach every student, and a proven research-based approach, authors Kenneth Miller and Joseph Levine continue to set the standard.Prentice Hall Biology delivers:-Clear, accessible writing-Up-to-date content-A student friendly approach-A powerful framework for connecting key concepts