The Human Genome Project finished sequencing human DNA. It seemed it was only a matter of time until we had all the answers to the secrets of life on this planet. The cutting-edge of biology, however, is telling us that we still don't even know all of the questions. How is it that, despite each cell in your body carrying exactly the same DNA, you don't have teeth growing out of your eyeballs or toenails on your liver? How is it that identical twins share exactly the same DNA and yet can exhibit dramatic differences in the way that they live and grow? It turns out that cells read the genetic code in DNA more like a script to be interpreted than a mould that replicates the same result each time. This is epigenetics and it's the fastest-moving field in biology today. The Epigenetics Revolution traces the thrilling path this discipline has taken over the last twenty years. Biologist Nessa Carey deftly explains such diverse phenomena as how queen bees and ants control their colonies, why tortoiseshell cats are always female, why some plants need a period of cold before they can flower, why we age, develop disease and become addicted to drugs, and much more. Most excitingly, Carey reveals the amazing possibilities for humankind that epigenetics offers for us all - and in the surprisingly near future.

    Assuming the reader has little prior knowledge of the subject its importance, the principles of the techniques used and their applications are all carefully laid out, with over 250 clearly presented two-colour illustrations. In addition to a number of informative changes to the text throughout the book, the final four chapters have been significantly updated and extended to reflect the striking advances made in recent years in the applications of gene cloning and DNA analysis in biotechnology: Extended chapter on agriculture including new material on glyphosate resistant plantsNew section on the uses of gene cloning and PCR in archaeologyCoverage of ethical concerns relating to pharming, gene therapy and GM crops Gene Cloning and DNA Analysis remains an essential introductory text to a wide range of biological sciences students; including genetics and genomics, molecular biology, biochemistry, immunology and applied biology. It is also a perfect introductory text for any professional needing to learn the basics of the subject. All libraries in universities where medical, life and biological sciences are studied and taught should have copies available on their shelves. View the Gene Cloning and DNA Analysis webpage at www.blackwellpublishing.com/genecloning

    By extracting the fundamental concepts from this enormous and ever-growing field, the authors tell the story of cell biology, and create a coherent framework through which non-expert readers may approach the subject. Written in clear and concise language, and beautifully illustrated, the book is enjoyable to read, and it provides a clear sense of the excitement of modern biology. Molecular Biology of the Cell sets forth the current understanding of cell biology (completely updated as of Autumn 2001), and it explores the intriguing implications and possibilities of the great deal that remains unknown. The hallmark features of previous editions continue in the Fourth Edition. The book is designed with a clean and open, single-column layout. The art program maintains a completely consistent format and style, and includes over 1,600 photographs, electron micrographs, and original drawings by the authors. Clear and concise concept headings introduce each section. Every chapter contains extensive references. Most important, every chapter has been subjected to a rigorous, collaborative revision process where, in addition to incorporating comments from expert reviewers, each co-author reads and reviews the other authors' prose. The result is a truly integrated work with a single authorial voice. Features : - Places the latest hot topics sensibly in context - including genomics, protein structure, array technology, stem cells and genetics diseases. - Incorporates and emphasises new genomic data. - All of molecular biology is brought together into one section (chapters 4-7) covering classically defined molecular biology and molecular genetics. - Two chapters deal exclusively with methods and contain information on the latest tools and techniques. - New chapters on "Pathogens, Infection, and Innate Immunity". - Cell Biology Interactive CD-ROM is packaged with every copy of the book. - Contains over 1,600 illustrations, electron micrographs and photographs, of which over 1,000 are originally conceived by the authors.

    Coverage includes basic procedures such as spays, castrations, and declaws, as well as more advanced surgeries that might be referred to specialists such as craniotomy, ventral slots, and lung lobectomy. Discussions of general surgical procedures include sterile technique, surgical instrumentation, suturing, preoperative care, and antibiotic use. Key sections provide clinically relevant coverage of soft tissue surgery, orthopedic surgery, and neurosurgery.Over 1500 full color illustrations provide exceptionally clear representations of anatomy and currently accepted surgical techniques, including approaches and closure.Over 600 full color photographs and radiographs offer clear images of specific disorders, diseases, and procedures.Information on the most efficient and cost-saving sterilization techniques including scrubless and waterless preparation solutions.General considerations and clinically relevant pathophysiology sections provide practical information for case management.Step-by-step instructions for surgical techniques are presented in italicized blue type for quick and easy reference.Special icons identify advanced procedures that should be referred to an experienced surgeon or specialist.Color-coded tables and boxes call attention to specific data, offering at-a-glance access to key information such as drug dosages, clinical signs, and analgesic protocols.Anesthesia Protocols provide quick and easy access to recommendations for anesthetizing animals with particular diseases or disorders.A new chapter on Fundamentals of Physical Rehabilitation details the basics of physical rehabilitation for practitioners who want to integrate physical therapy into practice.A new chapter on Principles of Minimally Invasive Surgery that describes the principles of performing surgery with the least instrumentation possible, including instrument selection and care and basic techniques.A new chapter on Surgery of the Eye that discusses diseases and disorders of the eye, their medical management, and corrective surgical procedures.Expanded coverage of perioperative multimodal analgesic therapy.Updated coverage of arthroscopy, canine elbow dysplasia, joint replacement, and management of osteoarthritis.The latest information on state-of-the-art radiologic techniques.

    Written by an author team, including a Noble Prize winner, this text presents the integration of Mendelian and molecular principles, providing students with the links between early genetics understanding and the molecular discoveries that have changed the way the field of genetics is viewed.

    David Quammen, together with series editor Burkhard Bilger, has assembled a remarkable group of writers whose selections appeared in periodicals from NATIONAL GEOGRAPHIC, SCIENCE, and THE NEW YORKER to PUERTO DEL SOL and DOUBLETAKE. Among the acclaimed writers represented in this volume are Richard Preston on “The Demon in the Freezer,” John McPhee bidding “Farewell to the Nineteeth Century,” Oliver Sacks remembering the “Brilliant Light” of his boyhood, and Wendell Berry going “Back to the Land.” Also including such literary lights as Anne Fadiman, David Guterson, Edward Hoagland, Natalie Angier, and Peter Matthiessen, this new collection presents selections bound together by their timelessness.

    Phages are also being used to detect and remove pathogens from our food supplies, both plant and animal. Also exciting is the use of phages as vehicles to delivery DNA vaccines, often directly to mammalian immune system cells. Recent work also suggests possible antitumor effects of phages. We stand on the edge of a whole new world of exploration and applications of microbiology. For over 20 years, and through five editions, Black's Microbiology: Principles and Explorations has captured students' imaginations. Her enthusiasm, passion, and knack for memorable stories and anecdotes bring the study of microbiology to life in a way few other texts can match. Now updated to reflect the latest topics in the field (e.g., SARS, bioterrorism, GMO's, geomicrobiology) and accompanied by state-of-the-art animations of key concepts, this new edition is sure to help inspire a new generation of enthusiasts for the dynamic science of microbiology. Critical Acclaim "I continue to find Black's text an excellent contribution to undergraduate Microbiology education." --Karen Messley, Rock Valley College "I like the conversational and informal style Black adopts throughout the book. This is a book, which could very well engage even the most reluctant student. It is comprehensive, nicely detailed, and incorporates many aids to teaching and learning..."--Iris Cook, Westchester CC "[The text] is a wonderful introduction into the world of microorganisms for students from a wide variety of backgrounds."--Jeff G. Leid, Northern Arizona University ..".I have found it [the book] accurate to a fault, brilliant at getting students motivated and interested in microbiology, and a great practical training book."--Gerard O'Donovan, University of North Texas Also available Laboratory Exercises in Microbiology, 2nd Edition Robert A. Pollack, et al. ISBN: 0-471-42082-4, 264 pages, paper, (c)2005 Written specifically for allied health students, this lab manual presents a variety of highly engaging activities and experiments that convey the basic concepts of microbiology.

    In this Very Short Introduction, renowned evolutionary scholar Bernard Wood traces the history of paleoanthropology from its beginnings inthe eighteenth century to today's latest fossil finds. Along the way we are introduced to the lively cast of characters, past and present, involved in evolutionary research. Although concentrating on the fossil evidence for human evolution, the book also covers the latest genetic evidence aboutregional variations in the modern human genome that relate to our evolutionary history. Wood draws on over thirty years of experience to provide an insiders view of the field, and demonstrates that our understanding of human evolution is critically dependent on advances in related sciences such aspaleoclimatology, geochronology, systematics, genetics, and developmental biology. This is an ideal introduction for anyone interested in the origins and development of humankind.

    This new edition, written with five new authors, has been brought fully up to date, and incorporates insights very recently derived from genome sequencing in a variety of organisms. The book is an authoritative and comprehensive survey of the fundamentals of molecular biology, from basic mechanisms to the elaborate role of gene regulation in embryonic development and evolution. Although updated, the twentyone chapters of the new edition retain the distinctive and celebrated features of the original work, including introductory chapters on the history of genetics and molecular biology and an emphasis throughout on the chemical underpinnings of molecular biology. The new team of authors brings to this edition awardwinning teaching experience and outstanding research achievements. By revealing the intellectual framework and experimental approaches that made new discoveries in the field possible, the new edition highlights the significance of the molecular approach for all of biology.

    The science consultant with "The X-Files" takes an official and entertaining look at the science behind this sci-fi phenomenon, revealing many scientific facts that are even more bizarre than fiction.

    By examining fossils and DNA, Shubin shows us that our hands actually resemble fish fins, our head is organized like that of a long-extinct jawless fish, and major parts of our genome look and function like those of worms and bacteria.Shubin makes us see ourselves and our world in a completely new light. Your Inner Fish is science writing at its finest-enlightening, accessible, and told with irresistible enthusiasm.

    From the physics of energy to climate change, and from spy technology to quantum computers, this is the only textbook to focus on the modern physics affecting the decisions of political leaders and CEOs and, consequently, the lives of every citizen. How practical are alternative energy sources? Can satellites really read license plates from space? What is the quantum physics behind iPods and supermarket scanners? And how much should we fear a terrorist nuke? This lively book empowers students possessing any level of scientific background with the tools they need to make informed decisions and to argue their views persuasively with anyone--expert or otherwise.Based on Richard Muller's renowned course at Berkeley, the book explores critical physics topics: energy and power, atoms and heat, gravity and space, nuclei and radioactivity, chain reactions and atomic bombs, electricity and magnetism, waves, light, invisible light, climate change, quantum physics, and relativity. Muller engages readers through many intriguing examples, helpful facts to remember, a fun-to-read text, and an emphasis on real-world problems rather than mathematical computation. He includes chapter summaries, essay and discussion questions, Internet research topics, and handy tips for instructors to make the classroom experience more rewarding.Accessible and entertaining, "Physics and Technology for Future Presidents" gives students the scientific fluency they need to become well-rounded leaders in a world driven by science and technology.Professors: A supplementary Instructor's Manual is available for this book. It is restricted to teachers using the text in courses. For information on how to obtain a copy, refer to: http: //press.princeton.edu/class_use/solutio...

    This book is an easy-to-understand and fun reference to this challenging subject. It explains the principles of organic chemistry in simple terms and includes worked-out problems to help readers get up to speed on the basics.

    Building a house would entail no more work than planting a seed in the ground. These scenarios may seem far-fetched, but pioneering geneticist George Church and science writer Ed Regis show that synthetic biology is bringing us ever closer to making such visions a reality. In Regenesis, Church and Regis explore the possibilities—and perils—of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. Until now, nature has been the exclusive arbiter of life, death, and evolution; with synthetic biology, we now have the potential to write our own biological future. Indeed, as Church and Regis show, it even enables us to revisit crucial points in the evolution of life and, through synthetic biological techniques, choose different paths from those nature originally took. Such exploits will involve far more than just microbial tinkering. Full-blown genomic engineering will make possible incredible feats, from resurrecting woolly mammoths and other extinct organisms to creating mirror life forms with a molecular structure the opposite of our own. These technologies—far from the out-of-control nightmare depicted in science fiction—have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span. A breathtaking look at the potential of this world-changing technology, Regenesis is nothing less than a guide to the future of life.

    In all the current highly publicized debates about creationism and its descendant "intelligent design," there is an element of the controversy that is rarely mentioned—the "evidence," the empirical truth of evolution by natural selection. Even Richard Dawkins and Stephen Jay Gould, while extolling the beauty of evolution and examining case studies, have not focused on the evidence itself. Yet the proof is vast, varied, and magnificent, drawn from many different fields of science. Scientists are observing species splitting into two and are finding more and more fossils capturing change in the past—dinosaurs that have sprouted feathers, fish that have grown limbs. Why Evolution Is True weaves together the many threads of modern work in genetics, paleontology, geology, molecular biology, and anatomy that demonstrate the "indelible stamp" of the processes first proposed by Darwin. In crisp, lucid prose accessible to a wide audience, Why Evolution Is True dispels common misunderstandings and fears about evolution and clearly confirms that this amazing process of change has been firmly established as a scientific truth.