Charles Darwin played a crucial part in turning heredity into a scientific question, and yet he failed spectacularly to answer it. The birth of genetics in the early 1900s seemed to do precisely that. Gradually, people translated their old notions about heredity into a language of genes. As the technology for studying genes became cheaper, millions of people ordered genetic tests to link themselves to missing parents, to distant ancestors, to ethnic identities. . . .But, Zimmer writes, "Each of us carries an amalgam of fragments of DNA, stitched together from some of our many ancestors. Each piece has its own ancestry, traveling a different path back through human history. A particular fragment may sometimes be cause for worry, but most of our DNA influences who we are--our appearance, our height, our penchants--in inconceivably subtle ways." Heredity isn't just about genes that pass from parent to child. Heredity continues within our own bodies, as a single cell gives rise to trillions of cells that make up our bodies. We say we inherit genes from our ancestors--using a word that once referred to kingdoms and estates--but we inherit other things that matter as much or more to our lives, from microbes to technologies we use to make life more comfortable. We need a new definition of what heredity is and, through Carl Zimmer's lucid exposition and storytelling, this resounding tour de force delivers it. Weaving historical and current scientific research, his own experience with his two daughters, and the kind of original reporting expected of one of the world's best science journalists, Zimmer ultimately unpacks urgent bioethical quandaries arising from new biomedical technologies, but also long-standing presumptions about who we really are and what we can pass on to future generations.

    In Barking Up the Wrong Tree, Eric Barker reveals the extraordinary science behind what actually determines success and most importantly, how anyone can achieve it. You’ll learn:• Why valedictorians rarely become millionaires, and how your biggest weakness might actually be your greatest strength • Whether nice guys finish last and why the best lessons about cooperation come from gang members, pirates, and serial killers• Why trying to increase confidence fails and how Buddhist philosophy holds a superior solution• The secret ingredient to “grit” that Navy SEALs and disaster survivors leverage to keep going• How to find work-life balance using the strategy of Genghis Khan, the errors of Albert Einstein, and a little lesson from Spider-ManBy looking at what separates the extremely successful from the rest of us, we learn what we can do to be more like them—and find out in some cases why it’s good that we aren’t. Barking Up the Wrong Tree draws on startling statistics and surprising anecdotes to help you understand what works and what doesn’t so you can stop guessing at success and start living the life you want.

    Armed with a healthy dose of wit and curiosity, medical journalist Randi Hutter Epstein reveals the “invigorating history” (Nature) of hormones and the age-old quest to control them through the back rooms, basements, and labs where endocrinology began.

    What’s more, we’re living in an uncharted social landscape with new conventions on how to relate—one where actual phone calls are reserved for Mom (if anyone), “dropping in” is unheard-of, and “flaking out” is routine.The Art of Showing Up offers a roadmap through this morass to true connection with your friends, your family, and yourself. Author Rachel Wilkerson Miller teaches that “showing up” means connecting with others in a way that makes them feel seen and supported. And that begins with showing up for yourself: recognizing your needs, understanding your physical and mental health, and practicing self-compassion. Only then can you better support other people; witness their joy, pain, and true selves; validate their experiences; and help ease their burden. When “showing up” for others, it’s not the grandest gesture that matters most—it’s how close you come to meeting your loved ones where they really are.

    In the early 1800s, women were dying in large numbers from treatable diseases because they avoided receiving medical care. Examinations performed by male doctors were often demeaning and even painful. In addition, women faced stigma from illness—a diagnosis could greatly limit their ability to find husbands, jobs or be received in polite society.Motivated by personal loss and frustration over inadequate medical care, Elizabeth Blackwell, Elizabeth Garrett Anderson and Sophia Jex-Blake fought for a woman’s place in the male-dominated medical field. For the first time ever, Women in White Coats tells the complete history of these three pioneering women who, despite countless obstacles, earned medical degrees and paved the way for other women to do the same. Though very different in personality and circumstance, together these women built women-run hospitals and teaching colleges—creating for the first time medical care for women by women.With gripping storytelling based on extensive research and access to archival documents, Women in White Coats tells the courageous history these women made by becoming doctors, detailing the boundaries they broke of gender and science to reshape how we receive medical care today.

    Now they explore the compulsion through a series of compelling case studies in the vein of Oliver Sacks. With vivid portraits that show us the traits by which you can identify a hoarder's piles on sofas and beds that make the furniture useless, houses that can be navigated only by following small paths called goat trails, vast piles of paper that the hoarders "churn" but never discard, even collections of animals and garbage; Frost and Steketee illuminate the pull that possessions exert on all of us. Whether we're savers, collectors, or compulsive cleaners, very few of us are in fact free of the impulses that drive hoarders to the extremes in which they live. For all of us with complicated relationships to our things, Stuff answers the question of what happens when our stuff starts to own us.

    Operations on the brain carry grave risks. Every day, leading neurosurgeon Henry Marsh must make agonizing decisions, often in the face of great urgency and uncertainty.If you believe that brain surgery is a precise and exquisite craft, practiced by calm and detached doctors, this gripping, brutally honest account will make you think again. With astonishing compassion and candor, Marsh reveals the fierce joy of operating, the profoundly moving triumphs, the harrowing disasters, the haunting regrets, and the moments of black humor that characterize a brain surgeon's life.Do No Harm provides unforgettable insight into the countless human dramas that take place in a busy modern hospital. Above all, it is a lesson in the need for hope when faced with life's most difficult decisions.

    These are the very same behaviors that typify good soldiering and foster a sense of belonging among troops, whether they’re fighting on the front lines or engaged in non-combat activities away from the action. Drawing from history, psychology, and anthropology, bestselling author Sebastian Junger shows us just how at odds the structure of modern society is with our tribal instincts, arguing that the difficulties many veterans face upon returning home from war do not stem entirely from the trauma they’ve suffered, but also from the individualist societies they must reintegrate into.A 2011 study by the Canadian Forces and Statistics Canada reveals that 78 percent of military suicides from 1972 to the end of 2006 involved veterans. Though these numbers present an implicit call to action, the government is only just taking steps now to address the problems veterans face when they return home. But can the government ever truly eliminate the challenges faced by returning veterans? Or is the problem deeper, woven into the very fabric of our modern existence? Perhaps our circumstances are not so bleak, and simply understanding that beneath our modern guises we all belong to one tribe or another would help us face not just the problems of our nation but of our individual lives as well.Well-researched and compellingly written, this timely look at how veterans react to coming home will reconceive our approach to veteran’s affairs and help us to repair our current social dynamic.

    Contrary to what the glossy magazines would have us believe, we do not enjoy potato chips because they crunch just like the insects our forebears snacked on. As Zuk argues, such beliefs incorrectly assume that we’re stuck—finished evolving—and have been for tens of thousands of years. She draws on fascinating evidence that examines everything from adults’ ability to drink milk to the texture of our ear wax to show that we’ve actually never stopped evolving. Our nostalgic visions of an ideal evolutionary past in which we ate, lived, and reproduced as we were “meant to” fail to recognize that we were never perfectly suited to our environment. Evolution is about change, and every organism is full of trade-offs.From debunking the caveman diet to unraveling gender stereotypes, Zuk gives an analysis of widespread paleofantasies and the scientific evidence that undermines them, all the while broadening our understanding of our origins and what they can really tell us about our present and our future.

    It's also about pain. Most important, it's about how to find the delicate balance between the two, and why now more than ever finding balance is essential. We're living in a time of unprecedented access to high-reward, high-dopamine stimuli: drugs, food, news, gambling, shopping, gaming, texting, sexting, Facebooking, Instagramming, YouTubing, tweeting... The increased numbers, variety, and potency is staggering. The smartphone is the modern-day hypodermic needle, delivering digital dopamine 24/7 for a wired generation. As such we've all become vulnerable to compulsive overconsumption.In Dopamine Nation, Dr. Anna Lembke, psychiatrist and author, explores the exciting new scientific discoveries that explain why the relentless pursuit of pleasure leads to pain...and what to do about it. Condensing complex neuroscience into easy-to-understand metaphors, Lembke illustrates how finding contentment and connectedness means keeping dopamine in check. The lived experiences of her patients are the gripping fabric of her narrative. Their riveting stories of suffering and redemption give us all hope for managing our consumption and transforming our lives. In essence, Dopamine Nation shows that the secret to finding balance is combining the science of desire with the wisdom of recovery."Brilliant... riveting, scary, cogent, and cleverly argued."--Beth Macy, author of DopesickINSTANT NEW YORK TIMES and LOS ANGELES TIMES BESTSELLER“Brilliant… riveting, scary, cogent, and cleverly argued.”—Beth Macy, author of DopesickAs heard on Fresh Air

    But treatment for it has not changed much in the last three decades. In the world of psychiatry, time has apparently stood still... until now. In this game-changing book, University of Cambridge Professor Edward Bullmore reveals the breakthrough new science on the link between depression and inflammation of the body and brain. He explains how and why we now know that mental disorders can have their root cause in the immune system, and outlines a future revolution in which treatments could be specifically targeted to break the vicious cycle of stress, inflammation and depression. The Inflamed Mind goes far beyond the clinic and the lab, representing a whole new way of looking at how mind, brain and body all work together in a sometimes misguided effort to help us survive in a hostile world. It offers insights into the story of Western medicine, how we have got it wrong as well as right in the past, and how we could start getting to grips with depression and other mental disorders much more effectively in the future.

    From kindergarten to college, American boys are, on average, less resilient and less ambitious than they were a mere twenty years ago. The gender gap in college attendance and graduation rates has widened dramatically. While Emily is working hard at school and getting A’s, her brother Justin is goofing off. He’s more concerned about getting to the next level in his video game than about finishing his homework.Now, Dr. Leonard Sax delves into the scientific literature and draws on more than twenty years of clinical experience to explain why boys and young men are failing in school and disengaged at home. He shows how social, cultural, and biological factors have created an environment that is literally toxic to boys. He also presents practical solutions, sharing strategies which educators have found effective in re-engaging these boys at school, as well as handy tips for parents about everything from homework, to video games, to medication.

    A simple muscle test can tell you what stimuli can strengthen or weaken you--how your body responds to stress, posture, specific foods, emotions, and your entire social and physical environments. Based on the role of the thymus gland in regulating body energy, this laboratory-tested method can guide you into a more vital, healthier way of life. Begin benefiting now from Dr. John Diamond's unique, personal synthesis of developments in psychiatry, preventive medicine, kinesiology, nutrition, and music therapy.

    Some people call it “ADHD,” “scatter brain,” or “brain fog.” And some people simply say they “just don’t feel like themselves”—and haven’t for a long time.      People are thinking and feeling worse than ever. Why? Because our brains are not getting the support they need to produce the essential brain chemicals that keep us energized, calm, focused, and inspired. In fact, if you look at the way that most of us live, it’s almost as though we had chosen a lifestyle deliberately intended to undermine our brain chemistry.      Fortunately, there is a solution. The Brain Fog Fix is a three-week program designed to help you naturally restore three of your brain’s most crucial chemicals: serotonin, dopamine, and cortisol. Rebalancing these three brain chemicals will, in turn, enable the rest of your brain’s chemistry to reach optimal levels. You will find yourself thinking more clearly, remembering more accurately, learning more quickly, and unleashing the floodgates of your creativity. You will also find yourself feeling more optimistic, calm, energized, connected, and inspired.      The good news is that this is easier than you think. Instead of trying to ambitiously overhaul one aspect of your life entirely with some difficult-to-maintain resolution, begin by making small and achievable changes in many different areas of your life.      “If I’ve learned one thing from the thousands of people I’ve treated, it’s that you have to take the whole person into account if you want to think and feel better.” —Dr. Mike Dow

    Be it hiring a new employee, investing in a financial interest, speaking with your child about drugs, confronting your significant other about suspected infidelity, or even dating someone new, having the ability to unmask a lie can have far-reaching and even life-altering consequences.As former CIA officers, Philip Houston, Michael Floyd, and Susan Carnicero are among the world’s best at recognizing deceptive behavior. Spy the Lie chronicles the captivating story of how they used a methodology Houston developed to detect deception in the counterterrorism and criminal investigation realms, and shows how these techniques can be applied in our daily lives.Through fascinating anecdotes from their intelligence careers, the authors teach listeners how to recognize deceptive behaviors, both verbal and nonverbal, that we all tend to display when we respond to questions untruthfully. For the first time, they share with the general public their methodology and their secrets to the art of asking questions that elicit the truth.Spy the Lie is a game-changer. You may never experience another book that has a more dramatic impact on your career, your relationships, or your future.©2012 Philip Houston, Susan Carnicero, Don Tennant, Michael Floyd (P)2012 Macmillan