Part One presents the general principles of pathophysiology and discusses the influence of the environment and the role of genetics in the development of disease. Part Two, organized by body system, examines normal anatomy and physiology, alterations of function in adults, and alterations of function in children.

    In that short time, many doctors decide on the likely diagnosis and best treatment. Often, decisions made this way are correct, but at crucial moments they can also be wrong -- with catastrophic consequences. In this myth-shattering book, Jerome Groopman pinpoints the forces and thought processes behind the decisions doctors make. Groopman explores why doctors err and shows when and how they can -- with our help -- avoid snap judgments, embrace uncertainty, communicate effectively, and deploy other skills that can profoundly impact our health. This book is the first to describe in detail the warning signs of erroneous medical thinking and reveal how new technologies may actually hinder accurate diagnoses. How Doctors Think offers direct, intelligent questions patients can ask their doctors to help them get back on track.Groopman draws on a wealth of research, extensive interviews with some of the country’s best doctors, and his own experiences as a doctor and as a patient. He has learned many of the lessons in this book the hard way, from his own mistakes and from errors his doctors made in treating his own debilitating medical problems.How Doctors Think reveals a profound new view of twenty-first-century medical practice, giving doctors and patients the vital information they need to make better judgments together.

    In other words, by all of us."--Dr. Bernie Siegel, author of Love, Medicine and MiraclesRule One for the neurologist in residence: "You ain't never the same when the air hits your brain." In this fascinating book, Dr. Frank Vertosick brings that fact to life through intimate portraits of patients and unsparing yet gripping descriptions of brain surgery.With insight, humor, and poignancy, Dr. Vertosick chronicles his remarkable evolution from naive young intern to world-class neurosurgeon, where he faced, among other challenges, a six week-old infant with a tumor in her brain, a young man struck down in his prime by paraplegia, and a minister with a .22 caliber bullet lodged in his skull. In candid detail, WHEN THE AIR HITS YOUR BRAIN illuminates both the mysteries of the mind and the realities of the operating room."Riveting."--Publishers Weekly

    Orville Rose's newfound peace is shattered by a telegram informing him of his mother's death. On his return to Columbia, a Hudson River town of quirky people and "plagued by breakage," he learns that his mother has willed him a large sum of money, the 1981 Chrysler, and her Victorian house in the center of town. But there's a catch: he must live in her house continuously for a year and thirteen days. As he struggles with his decision -- whether to stay and meet the terms of the will or return to his love and life in Italy -- Orville reconnects with Bill Starbuck, the town doctor who mentored a young Orville and who practices a long-ago kind of medicine that treats the working poor, people neglected and forgotten by the medical and insurance industries. Now in his seventies, and in need of help with the practice, Bill convinces Orville to stay. During the course of his year and thirteen days, Orville reacquaints himself with Columbia and Colombians. He reunites with his sister and niece and comes to terms with old rivals and bitter memories. And he doctors a community in desperate need of care. He also meets Miranda Braak, a remarkable young single mother who aspires to be the town historian. Her knowledge of and reverence for the past challenges Orville to examine his own history, and her courage, integrity, and love challenge him to grow. In this story filled with wit, pointed insight, and drama, Orville learns what it means to be a healer, and to be healed.

    In riveting first-person prose, Dr. Brendan Reilly takes us to the front lines of medicine today. Whipsawed by daily crises and frustrations, Reilly must deal with several daunting challenges simultaneously: the extraordinary patients under his care on the teeming wards of a renowned teaching hospital; the life-threatening illnesses of both of his ninety-year-old parents; and the tragic memory of a cold case from long ago that haunts him still. As Reilly’s patients and their families survive close calls, struggle with heartrending decisions, and confront the limits of medicine’s power to cure, One Doctor lays bare a fragmented, depersonalized, business-driven health-care system where real caring is hard to find. Every day, Reilly sees patients who fall through the cracks and suffer harm because they lack one doctor who knows them well and relentlessly advocates for their best interests.Filled with fascinating characters in New York City and rural New England — people with dark secrets, mysterious illnesses, impossible dreams, and many kinds of courage — One Doctor tells their stories with sensitivity and empathy, reminding us of professional values once held dear by all physicians. But medicine has changed enormously during Reilly’s career, for both better and worse, and One Doctor is a cautionary tale about those changes. It is also a hopeful, inspiring account of medicine’s potential to improve people’s lives, Reilly’s quest to understand the "truth" about doctoring, and a moving testament to the difference one doctor can make.

    Jen Gunter now delivers the definitive book on vaginal health, answering the questions you've always had but were afraid to ask--or couldn't find the right answers to. She has been called Twitter's resident gynecologist, the Internet's OB/GYN, and one of the fiercest advocates for women's health...and she's here to give you the straight talk on the topics she knows best.Does eating sugar cause yeast infections? Does pubic hair have a function? Should you have a vulvovaginal care regimen?Will your vagina shrivel up if you go without sex?What's the truth about the HPV vaccine?So many important questions, so much convincing, confusing, contradictory misinformation! In this age of click bait, pseudoscience, and celebrity-endorsed products, it's easy to be overwhelmed--whether it's websites, advice from well-meaning friends, uneducated partners, and even healthcare providers. So how do you separate facts from fiction? OB-GYN Jen Gunter, an expert on women's health--and the internet's most popular go-to doc--comes to the rescue with a book that debunks the myths and educates and empowers women. From reproductive health to the impact of antibiotics and probiotics, and the latest trends, including vaginal steaming, vaginal marijuana products, and jade eggs, Gunter takes us on a factual, fun-filled journey. Discover the truth about:- The vaginal microbiome - Genital hygiene, lubricants, and hormone myths and fallacies - How diet impacts vaginal health - Stem cells and the vagina - Cosmetic vaginal surgery - What changes to expect during pregnancy, after childbirth, and through menopause - How medicine fails women by dismissing symptomsPlus: - Thongs vs. lace: the best underwear for vaginal health - How to select a tampon - The full glory of the clitoris and the myth of the G Spot... And so much more. Whether you're a twenty-six-year-old worried that her labia are "uncool" or a sixty-six-year-old dealing with painful sex, this comprehensive guide is sure to become a lifelong trusted resource.

    She's barely out of the car when she's called to assist the midwife with a bride who's gone into labour in the middle of her own wedding reception. And so her adventures begin...As a health visitor Nurse Sarah is as green as grass but she puts her best foot into wellies and braves the mad dogs, killer ganders and muddy tracks of the farming community. Despite set-backs young Sarah is determined to help the mums she meets, from struggling young mothers in unmodernised farmhouses, to doyennes of the county dinner party set who slave over stuffed olive hors-d'oeuvres.Village life in 1970s isn't always quite the Good Life Sarah's been expecting; her attempts at self-sufficiency and cider making lead to drunk badgers and spirited house parties - but will it be the clergyman, the vet or the young doctor that win Sarah's heart. During her first year in Kent, Nurse Sarah Hill get stuck in - reuniting families and helping mums in the midst of community full of ancient feuds, funny little ways and just a bit of magic.

    Whether inserting a breathing tube or spinal needle, delivering electric shocks, searching for cancer on X-rays or telling stories to his two young daughters at night, Dr. Mathur's heartwarming and occasionally hilarious stories depict human relationships at many levels. The new doctor on the prairie is also a husband, a father, a neighbor, and an immigrant. The first year of practice is critical for all doctors, rocked by anxiety and fear. The love and support of family and patients makes it possible to persevere and overcome these challenges. These stories portray a doctor's life at its best and its worst, and show the personal toll of practicing medicine as well as the many rewards of working in an underserved hospital. This biography reveals that, though medicine is indeed demanding and difficult, a little humor, compassion, and humility makes it fulfilling and inspiring.

    While maintaining the hallmark features of previous editions, the Fourth Edition has been completely updated. It includes new Key Concepts at the beginning of each chapter and annotated further reading at the conclusion of each chapter, to help readers navigate the wealth of information in this subject.The text has been restructured so genomic technologies are integrated throughout, and next generation sequencing is included. Genetic testing, screening, approaches to therapy, personalized medicine, and disease models have been brought together in one section. Coverage of cell biology including stem cells and cell therapy, studying gene function and structure, comparative genomics, model organisms, noncoding RNAs and their functions, and epigenetics have all been expanded.

    A book for medical students and doctors.

     Common, yet little understood, tongue-ties can lead to a myriad of problems, including difficulty when nursing, speaking or eating. In the most crucial and formative parts of children’s lives, tongue-ties have a significant effect on their well-being. Many parents and professionals alike want to know what can be done, and how best to treat these patients and families. And now, there are answers. Tongue-Tied: How a Tiny String Under the Tongue Impacts Nursing, Feeding, Speech, and More is an exhaustive and informative guide to this misunderstood affliction. Along with a team of medical specialists, author Dr. Richard Baxter demystifies tongue-ties and spells out how this condition can be treated comprehensively, safely and comfortably. Starting with a broad history of tongue-ties, this invaluable guide covers 21st-century assessment techniques and treatment options available for tethered oral tissues. Various accounts of patient challenges and victories are prominently featured as well. With the proper diagnosis and treatment, tethered oral tissues can be released with minimal discomfort, resulting in improvements during nursing, speaking, and feeding, while also reducing the incidence of dental issues, headaches, and even neck pain for children through adults. Aimed at both parents and professionals, Tongue-Tiedencourages those affected while providing reassuring and valuable information. Dr. Baxter and his qualified team have pooled their expertise to make a difference in the lives of people. Having examined and treated newborns to adults with oral restrictions since the early 1980s, I have never seen such a complete and thorough study of the subject. Dr. Baxter has covered it all! His own personal experience was a great motivator to make this book a must-read for parents, physicians, dentists, lactation consultants, and therapists of all kinds. Greg Notestine, DDS, AAACD Founding Member and Past Director, International Affiliation of Tongue-Tie Professionals (IATP) There can be no greater feeling than to see that I have been able to stimulate individuals like Dr. Baxter to add to the body of knowledge needed to educate the healthcare community as well as parents on the need to have tethered oral tissues evaluated for the many potential problems related to the tongue, which is not just a muscle, but a part of our body that can affect many of the body’s systems, infant growth and development, speech and much more. Congratulations on writing this excellent book. Larry Kotlow, DDS Pioneer and Expert on Tethered Oral Tissues Tongue-Tied is a revolutionary resource for parents, patients, and professionals alike. Such a detailed, comprehensive, and research-based resource has not existed until now! As a speech-language pathologist and certified orofacial myologist, this will be on the top shelf of my library and will be a resource I recommend to my colleagues, patients, and students. Thank you for filling this gap! Autumn R. Henning, MS, CCC-SLP, COM Founder, TOTS Training How refreshing to have a resource for parents and professionals based on clinical expertise and current research! Tongue-Tied is a straight-forward, no-nonsense approach to the influence of tethered oral tissues on both speech and feeding development. Melanie Potock, MA, CCC-SLP Author of Adventures in Veggieland & co-author of Raising a Healthy Happy Eater As a surgical specialist and clinical researcher in the area of tethered oral tissues for close to 20 years, I have been waiting for a comprehensive text of this subject.

    Through her teachings and his own mind-bending experiences, he gives us a glimpse into an alternate reality.

    Vivid, hilarious and often alarming, his columns have found a cult following among doctors and patients alike. Now these pieces are available in one volume.

    We like to imagine that it’s based on evidence and the results of fair tests. In reality, those tests are often profoundly flawed. We like to imagine that doctors are familiar with the research literature surrounding a drug, when in reality much of the research is hidden from them by drug companies. We like to imagine that doctors are impartially educated, when in reality much of their education is funded by industry. We like to imagine that regulators let only effective drugs onto the market, when in reality they approve hopeless drugs, with data on side effects casually withheld from doctors and patients.All these problems have been protected from public scrutiny because they’re too complex to capture in a sound bite. But Dr. Ben Goldacre shows that the true scale of this murderous disaster fully reveals itself only when the details are untangled. He believes we should all be able to understand precisely how data manipulation works and how research misconduct on a global scale affects us. In his own words, “the tricks and distortions documented in these pages are beautiful, intricate, and fascinating in their details.” With Goldacre’s characteristic flair and a forensic attention to detail, Bad Pharma reveals a shockingly broken system and calls for something to be done. This is the pharmaceutical industry as it has never been seen before.

    Judy Melinek began her training as a New York City forensic pathologist. With her husband T.J. and their toddler Daniel holding down the home front, Judy threw herself into the fascinating world of death investigation, performing autopsies, investigating death scenes, counseling grieving relatives. Working Stiff chronicles Judy's two years of training, taking readers behind the police tape of some of the most harrowing deaths in the Big Apple, including a firsthand account of the events of September 11, the subsequent anthrax bio-terrorism attack, and the disastrous crash of American Airlines flight 587.Lively, action-packed, and loaded with mordant wit, Working Stiff offers a firsthand account of daily life in one of America's most arduous professions, and the unexpected challenges of shuttling between the domains of the living and the dead. The body never lies, and through the murders, accidents, and suicides that land on her table, Dr. Melinek lays bare the truth behind the glamorized depictions of autopsy work on shows like CSI and Law and Order to reveal the secret story of the real morgue.