He tells of the large science-steeped family who fostered his early fascination with chemistry. There follow his years at boarding school where, though unhappy, he developed the intellectual curiosity that would shape his later life. And we hear of his return to London, an emotionally bereft ten-year-old who found solace in his passion for learning. Uncle Tungsten radiates all the delight and wonder of a boy’s adventures, and is an unforgettable portrait of an extraordinary young mind.

    Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with - and perished from - for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. From the Persian Queen Atossa, whose Greek slave cut off her malignant breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee’s own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive—and to increase our understanding of this iconic disease. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

    Mikel Jollett was born into one of the country’s most infamous cults, and subjected to a childhood filled with poverty, addiction, and emotional abuse. Yet, ultimately, his is a story of fierce love and family loyalty told in a raw, poetic voice that signals the emergence of a uniquely gifted writer.We were never young. We were just too afraid of ourselves. No one told us who we were or what we were or where all our parents went. They would arrive like ghosts, visiting us for a morning, an afternoon. They would sit with us or walk around the grounds, to laugh or cry or toss us in the air while we screamed. Then they’d disappear again, for weeks, for months, for years, leaving us alone with our memories and dreams, our questions and confusion. …So begins Hollywood Park, Mikel Jollett’s remarkable memoir. His story opens in an experimental commune in California, which later morphed into the Church of Synanon, one of the country’s most infamous and dangerous cults. Per the leader’s mandate, all children, including Jollett and his older brother, were separated from their parents when they were six months old, and handed over to the cult’s “School.” After spending years in what was essentially an orphanage, Mikel escaped the cult one morning with his mother and older brother. But in many ways, life outside Synanon was even harder and more erratic.In his raw, poetic and powerful voice, Jollett portrays a childhood filled with abject poverty, trauma, emotional abuse, delinquency and the lure of drugs and alcohol. Raised by a clinically depressed mother, tormented by his angry older brother, subjected to the unpredictability of troubled step-fathers and longing for contact with his father, a former heroin addict and ex-con, Jollett slowly, often painfully, builds a life that leads him to Stanford University and, eventually, to finding his voice as a writer and musician.Hollywood Park is told at first through the limited perspective of a child, and then broadens as Jollett begins to understand the world around him. Although Mikel Jollett’s story is filled with heartbreak, it is ultimately an unforgettable portrayal of love at its fiercest and most loyal.

    Armstrong writes about her experience as one of only a few people to participate in an experimental treatment for depression involving ten rounds of a chemically induced coma approximating brain death.For years, Heather B. Armstrong has alluded to her struggle with depression on her website. But in 2016, Heather found herself in the depths of a depression she just couldn’t shake, an episode darker and longer than anything she had previously experienced. This book recalls the torturous eighteen months of suicidal depression she endured and the month-long experimental study in which doctors used propofol anesthesia to quiet all brain activity for a full fifteen minutes before bringing her back from a flatline. Ten times. The experience wasn’t easy. Not for Heather or her family. But a switch was flipped, and Heather hasn’t experienced a single moment of suicidal depression since. The Valedictorian of Being Dead brings to light a groundbreaking new treatment for depression.

    She offered up more than 5,000 orphans tailored to the wish lists of eager parents--hiding the fact that many weren't orphans at all, but stolen sons and daughters of poor families, desperate single mothers, and women told in maternity wards that their babies had died.The publication of Lisa Wingate's novel Before We Were Yours brought new awareness of Tann's lucrative career in child trafficking. Adoptees who knew little about their pasts gained insight into the startling facts behind their family histories. Encouraged by their contact with Wingate and award-winning journalist Judy Christie, who documented the stories of fifteen adoptees in this book, many determined Tann survivors set out to trace their roots and find their birth families.Before and After includes moving and sometimes shocking accounts of the ways in which adoptees were separated from their first families. Often raised as only children, many have joyfully reunited with siblings in the final decades of their lives. In Before and After, Wingate and Christie tell of first meetings that are all the sweeter and more intense for time missed and of families from very different social backgrounds reaching out to embrace better-late-than-never brothers, sisters, and cousins. In a poignant culmination of art meeting life, long-silent victims of the tragically corrupt system return to Memphis with Wingate and Christie to reclaim their stories at a Tennessee Children's Home Society reunion . . . with extraordinary results.

    Over the course of minutes, they would kill twelve students and a teacher and wound twenty-four others before taking their own lives.   For the last sixteen years, Sue Klebold, Dylan’s mother, has lived with the indescribable grief and shame of that day. How could her child, the promising young man she had loved and raised, be responsible for such horror? And how, as his mother, had she not known something was wrong? Were there subtle signs she had missed? What, if anything, could she have done differently?   These are questions that Klebold has grappled with every day since the Columbine tragedy. In A Mother’s Reckoning, she chronicles with unflinching honesty her journey as a mother trying to come to terms with the incomprehensible. In the hope that the insights and understanding she has gained may help other families recognize when a child is in distress, she tells her story in full, drawing upon her personal journals, the videos and writings that Dylan left behind, and on countless interviews with mental health experts.   Filled with hard-won wisdom and compassion, A Mother’s Reckoning is a powerful and haunting book that sheds light on one of the most pressing issues of our time. And with fresh wounds from the recent Newtown and Charleston shootings, never has the need for understanding been more urgent.  All author profits from the book will be donated to research and to charitable organizations focusing on mental health issues.

    In this captivating fusion of science, history and personal memoir, writer David Adam explores the weird thoughts that exist within every mind, and how they drive millions of us towards obsessions and compulsions.David has suffered from OCD for twenty years, and The Man Who Couldn’t Stop is his unflinchingly honest attempt to understand the condition and his experiences. What might lead an Ethiopian schoolgirl to eat a wall of her house, piece by piece; or a pair of brothers to die beneath an avalanche of household junk that they had compulsively hoarded? At what point does a harmless idea, a snowflake in a clear summer sky, become a blinding blizzard of unwanted thoughts? Drawing on the latest research on the brain, as well as historical accounts of patients and their treatments, this is a book that will challenge the way you think about what is normal, and what is mental illness.Told with fierce clarity, humour and urgent lyricism, this extraordinary book is both the haunting story of a personal nightmare, and a fascinating doorway into the darkest corners of our minds.

    The daughter they secreted away made all the difference.Joe and Rose Kennedy’s strikingly beautiful daughter Rosemary attended exclusive schools, was presented as a debutante to the Queen of England, and traveled the world with her high-spirited sisters. And yet, Rosemary was intellectually disabled — a secret fiercely guarded by her powerful and glamorous family.  Major new sources — Rose Kennedy’s diaries and correspondence, school and doctors' letters, and exclusive family interviews — bring Rosemary alive as a girl adored but left far behind by her competitive siblings. Kate Larson reveals both the sensitive care Rose and Joe gave to Rosemary and then — as the family’s standing reached an apex — the often desperate and duplicitous arrangements the Kennedys made to keep her away from home as she became increasingly intractable in her early twenties. Finally, Larson illuminates Joe’s decision to have Rosemary lobotomized at age twenty-three, and the family's complicity in keeping the secret.  Rosemary delivers a profoundly moving coda: JFK visited Rosemary for the first time while campaigning in the Midwest; she had been living isolated in a Wisconsin institution for nearly twenty years. Only then did the siblings understand what had happened to Rosemary and bring her home for loving family visits. It was a reckoning that inspired them to direct attention to the plight of the disabled, transforming the lives of millions.

    "A stunning memoir from the astronaut who spent a record-breaking year aboard the International Space Station – a candid account of his remarkable voyage, the journeys that preceded it, and his colorful formative years." Inside book cover comments.

    As the cancer progressed and was treated, the author experienced behavioral and cognitive symptoms connected to a range of mental disorders, including her professional specialty, schizophrenia. Lipska's family and associates were alarmed by the changes in her behavior, which she failed to acknowledge herself. Gradually, after a course of immunotherapy, Lipska returned to normal functioning, recalled her experience and, through her knowledge of neuroscience, identified the ways in which her brain changed during treatment. Lipska admits her condition was unusual; after recovery she was able to return to her research and resume her athletic training and compete in a triathalon. Most patients with similar brain cancers rarely survive to describe their ordeal. Lipska's memoir, coauthored with journalist McArdle, shows that strength and courage but also a encouraging support network are vital to recovery

    Many people think of microbes as germs to be eradicated, but those that live with us—the microbiome—build our bodies, protect our health, shape our identities, and grant us incredible abilities. In this astonishing book, Ed Yong takes us on a grand tour through our microbial partners, and introduces us to the scientists on the front lines of discovery. Yong, whose humor is as evident as his erudition, prompts us to look at ourselves and our animal companions in a new light—less as individuals and more as the interconnected, interdependent multitudes we assuredly are. The microbes in our bodies are part of our immune systems and protect us from disease. Those in cows and termites digest the plants they eat. In the deep oceans, mysterious creatures without mouths or guts depend on microbes for all their energy. Bacteria provide squids with invisibility cloaks, help beetles to bring down forests, and allow worms to cause diseases that afflict millions of people. I Contain Multitudes is the story of these extraordinary partnerships, between the creatures we are familiar with and those we are not. It reveals how we humans are disrupting these partnerships and how we might manipulate them for our own good. It will change both our view of nature and our sense of where we belong in it.

    Complications lays bare a science not in its idealized form but as it actually is--uncertain, perplexing, and profoundly human.Complications is a 2002 National Book Award Finalist for Nonfiction.

    The bestselling author of Shadow Divers returns with a riveting story of exploration, mystery, and the discovery of an unknown world--this time about one man's incredible odyssey from blindness into sight.

    Dea Bala never expected the outpouring of responses that would follow. She was working as a lobbyist when the idea was born: she'd chat up respondents on the phone or at a coffee shop and let them tell her about their lives. Dea Bala soon had to quit her day job to make time for all of the Craigslist sessions. She took notes during each conversation and journaled about the emotional experience to expertly inhabit the voice of each subject. What emerges is a collection of narratives, all in first person, of anonymous people revealing their deepest, darkest secrets; or at least the most poignant moments of their lives. Infidelity, addiction, loss, corruption, the search for unconditional love—reading these carefully, empathetically crafted monologues reveals how suffering is something we all have in common. Each tragedy or triumph is unique, but the intensity of feeling is not.

    Julia Cooke’s intimate storytelling weaves together the real-life stories of a memorable cast of characters, from Lynne Totten, a science major who decided life in a lab was not for her, to Hazel Bowie, one of the relatively few black stewardesses of the era, as they embraced the liberation of their new jet-set life. Cooke brings to life the story of Pan Am stewardesses’ role in the Vietnam War, as the airline added runs from Saigon to Hong Kong for planeloads of weary young soldiers straight from the battlefields, who were off for five days of R&R, and then flown back to war. Finally, with Operation Babylift—the dramatic evacuation of 2,000 children during the fall of Saigon—the book’s special cast of stewardesses unites to play an extraordinary role on the world stage.