Jerry Avorn has some sobering news. Drawing on more than twenty-five years of patient care, teaching, and research at Harvard Medical School, he shares his firsthand experience of the wide gap in our knowledge of the effectiveness of one medication as compared to another. In Powerful Medicines, he reminds us that every pill we take represents a delicate compromise between the promise of healing, the risk of side effects, and an increasingly daunting price. The stakes on each front grow higher every year as new drugs with impressive power, worrisome side effects, and troubling costs are introduced.This is a comprehensive behind-the-scenes look at issues that affect everyone: our shortage of data comparing the worth of similar drugs for the same condition; alarming lapses in the detection of lethal side effects; the underuse of life-saving medications; lavish marketing campaigns that influence what doctors prescribe; and the resulting upward spiral of costs that places vital drugs beyond the reach of many Americans.In this engagingly written book, Dr. Avorn asks questions that will interest every consumer: How can a product judged safe by the Food and Drug Administration turn out to have unexpectedly lethal side effects? Why has the nation’s drug bill been growing at nearly 20 percent per year? How can physicians and patients pick the best medication in its class? How do doctors actually make their prescribing decisions, and why do those decisions sometimes go wrong? Why do so many Americans suffer preventable illnesses and deaths that proper drug use could have averted? How can the nation gain control over its escalating drug budget without resorting to rationing or draconian governmental controls?Using clinical case histories taken from his own work as a practitioner, researcher, and advocate, Dr. Avorn demonstrates the impressive power of the well-conceived prescription as well as the debacles that can result when medications are misused. He describes an innovative program that employs the pharmaceutical industry’s own marketing techniques to reduce use of some of the most overprescribed and overpriced products. Powerful Medicines offers timely and practical advice on how the nation can improve its drug-approval process, and how patients can work with doctors to make sure their prescriptions are safe, effective, and as affordable as possible. This is a passionate and provocative call for action as well as a compelling work of clear-headed science.From the Hardcover edition.

    Sandy Johnson was in shock. Her husband, Duane, and young daughter, Sherrie, were violently ill when word arrived that her infant nephew just died of mysterious causes. Days earlier, the entire family was happy, healthy, and living the American dream. Now they were at the center of a terrifying medical crisis.   Duane soon died in a condition unlike anything the doctors had ever seen. As they raced to discover what disease or toxin could have done so much damage so quickly, Lt. Foster Burchard of the Omaha police began to suspect foul play. Sandy herself became a primary suspect, as did her ex-boyfriend Steven Harper—a man prone to violence who never got over their breakup.   In Toxic Love, investigative reporter and true crime author Tomás Guillén offers a detailed and vivid account of this baffling case from the day of the poisoning to the harrowing trial and the murderer’s eventual suicide on death row.

    

    Perhaps no questions cause more confusion than the ones that arise when you are pulled out of a thriving life of work that benefits the world, only to spend your hours, days, and weeks languishing in bed. It just doesn’t make sense. Why, God? Why would you take away my thriving career when it took me years to get to this point? Why would you take away my ability to serve and help and contribute? In this first book in the Chronic Pain and the Christian Life series, explore what it looks like to live a life of work, service, and rest, even when the pain doesn’t go away.

    She is accompanied on her journey by a fantastic cast of characters, including her Cry Lady (who always makes appearances at inopportune times) and perky Dolores the Prosthesis, as well as a convoy of health professionals, family members, friends, and neighbors. Both heartbreaking and hilarious, Most of Me offers a unique glimpse into a creative mind, an ailing body, and the restorative power of humor and fantasy.

    Huge progress in research over the past decade has established dysfunction in sleep, pain, and the stress response in fibromyalgia. Current research suggests that the muscle pain of fibromyalgia may be generated from the fascia, the connective tissue surrounding each muscle of the body.As medical understanding of fibromyalgia has increased, so have our treatment options. With the unique perspective of a physician studying fibromyalgia “from the inside,” Dr. Liptan explains the most up-to-date science and guides you to the most effective treatments from both conventional and alternative medicine.ABOUT THE AUTHOR: Ginevra Liptan, MD, is a graduate of Tufts University School of Medicine, and is board-certified in internal medicine. After developing fibromyalgia as a medical student, she spent many years using herself as a guinea pig in a search for effective treatments. She is now medical director of the Frida Center for Fibromyalgia, and an associate professor at Oregon Health and Science University.

    Most arrive safely and go home with their families in a matter of days. But not all babies come into the world healthy and almost half a million arrive well before they are expected. These newborns need tiny medicine. Told from the first-person perspective, Dr. Chris DeRienzo—a neonatologist, health system leader and frequent keynote speaker—walks readers through the human experience of caring for the world's smallest and sickest patients. His stories share the absurd and the sublime parts of being a doctor and detail how they have shaped who he is as a husband, father, and person. Readers will learn the secrets of the NICU, the loneliness that comes with life and death decisions, and the incredibly powerful sense of purpose and triumph that comes with just making it through the night and keeping everyone alive. In the end, this book delivers an insider's view of a doctor's life never before accessible without a white coat.

    We'll point out the best of Disney's ships and itineraries, including a couple of stellar restaurants, top-notch children's activities, and Castaway Cay, one of the best vacation islands in the Caribbean. We'll also tell you which on-board entertainment and restaurants should be skipped, including what to do instead. Along the way we'll show you how to save money, choose the right stateroom, ship, and itinerary, and how to get to and from your cruise with ease.

    This unique form of therapy blends horse sense with common sense. Wyatt uses the horse as a metaphor, explaining that how you relate to this animal will tell how you relate to all living things, hence the title "It's Not About The Horse". Using this analogy and case studies Wyatt shows the reader how to understand what they have learned over the course of their lifetime and explains how to examine what works for or against them. Wyatt then goes on to explain, drawing from his own life experience how anyone that wants to grow and really know who they are must travel through uncharted territory, the only place where you learn anything.

    But then she didn't count on having a gypsy wedding...It's rare for a 'gorger', or non-traveller, to marry into the gypsy community. But after a shocking childhood tragedy, Sam found the comfort she needed from an unxpected source - Patrick and his family of travellers.Gypsy Bride is the heartwarming true story of how an ordinary girl finds herself discovering an extraordinary world. A place where 'grabbing' is a sign a boy fancies you, six-year-olds get spray tans, and christenings, weddings and funerals are jaw-droppingly flamboyant.This love story is more than boy meets girl. It's about a girl who falls in love with a whole race of people and their wonderful ways.

    She tried and failed many diets, but her life took a turn when she was forced to face a harsh reality: her weight crept up to 287 pounds and she had a BMI reading of forty-two. Pre-diabetic and diagnosed as morbidly obese with a fatty liver and high blood pressure, Bernadette decided that it was the time to ditch the fad diets and take matters into her own hands to turn her life around. She began asking those she knew well—the glamorous models she worked with—learning about their healthy eating habits and their tips on staying trim. She further researched medical reports and nutrition papers until finally—by trial, error, and a lot of experimentation—she created a healthy lifestyle plan that was quick to read, easy to understand, and, most importantly, worked long term. Following her new rules, Bernadette went on to lose more than sixty-six pounds in thirty weeks. The Little Book of Big Weight Loss is for anyone who has grown tired of all the confusing, conflicting advice and complicated diet plans. Inspiring and packed with invaluable tips and strategies, this guide provides a fresh, simple, can-do approach to dieting and can help you get on track to achieving your goals and losing weight long term.

    The rotator cuff, a group of four, flat tendons that connect to the critical muscles that stabilize your shoulder, can cause a lot more problems than you might think. Consider a few of these statistics from the published literature: .It's simply just a matter of time until the majority of shoulders get a rotator cuff tear. According to Magnetic Resonance Imaging (MRI) scans, approximately 4% of people under forty years of age have a torn rotator cuff. After age sixty, however, 54% of people have one (Sher 1995). .Once the rotator cuff gets torn, it doesn't look good either. One study followed a group of patients with tears in their rotator cuffs and found that 80% of the them went on to either enlarge or turn into full thickness tears-in less than a two-year period (Yamanaka 1994). As you can tell, rotator cuff problems aren't just for elite athletes. Seriously consider investing just a few minutes a week doing the simple exercises in this book if you: .have been diagnosed with either a partial or full thickness rotator cuff tear (yes, many studies show that even full thickness tears can be helped with exercise!) .experience shoulder pain .do upper body weight lifting .have a job or play a sport where you do a lot of work with your arms above shoulder level .have been diagnosed with "impingement syndrome" .want a healthy and properly functioning rotator cuff So whether you already suffer from a rotator cuff problem, or simply want to prevent one, Treat Your Own Rotator Cuff will guide you step-by-step through an evidence-based program that can iron-plate your shoulders in just minutes a week. Jim Johnson, P.T., is a physical therapist who has spent over fifteen years treating both inpatients and outpatients with a wide range of pain and mobility problems. He has written many books based completely on published research and controlled trials including The Multifidus Back Pain Solution, Treat Your Own Knees, The No-Beach, No-Zone, No-Nonsense Weight Loss Plan: A Pocket Guide to What Works, and The Sixty-Second Motivator. His books have been translated into other languages and thousands of copies have been sold worldwide. Besides working full-time as a clinician in a large teaching hospital and writing books, Jim Johnson is a certified Clinical Instructor by the American Physical Therapy Association and enjoys teaching physical therapy students from all over the United States.

    She witnesses nurses drawing straws to see who would tend to the patient inside, all of them reluctant to enter the room. Out of impulse, Ruth herself enters the quarantined space and immediately begins to care for the young man who cries for his mother in the last moments of his life. Before she can even process what she's done, word spreads in the community that Ruth is the only person willing to help these young men afflicted by AIDS, and is called upon to nurse them. As she forges deep friendships with the men she helps, she works tirelessly to find them housing and jobs, even searching for funeral homes willing to take their bodies - often in the middle of the night. She cooks meals for tens of people out of discarded food found in the dumpsters behind supermarkets, stores rare medications for her most urgent patients, teaches sex-ed to drag queens after hours at secret bars, and becomes a beacon of hope to an otherwise spurned group of ailing gay men on the fringes of a deeply conservative state.Throughout the years, Ruth defies local pastors and nurses to help the men she cares for: Paul and Billy, Angel, Chip, Todd and Luke. Emboldened by the weight of their collective pain, she fervently advocates for their safety and visibility, ultimately advising Governor Bill Clinton on the national HIV-AIDS crisis.This deeply moving and elegiac memoir honors the extraordinary life of Ruth Coker Burks and the beloved men who fought valiantly for their lives with AIDS during a most hostile and misinformed time in America.

    But, fortunately, this is not the case. Like any other skill, mindfulness can be taught, though some will obviously take to it faster than others. In this book, author Stefan Cain teaches you how to train your brain to work more effectively in a variety of ways using several different exercises and methods. Stefan Cain has studied the human brain for years, particularly in regards to its functionality. His research and experiments have shown him that the brain, like other parts of the body, can be shaped, sculpted, and, eventually, trained in such a way as to promote increased mindfulness. By following the methods outlined in this book, and by coming to understand how the brain works, you will learn how to: • Improve your observational skills—you could be the next Sherlock Holmes! • Improve your memory • Increase your awareness • Become more creative • Make solid deductions • Use critical thinking • Use your intuition By reading, understanding, and then implementing the techniques described in this book, you can be a better, more productive, and less stressed you in no time at all.

    As a mother of seven, she knows we don't just need to be told what kind of women we should be. We need some help getting there.Drawing from her own experience of balancing marriage, motherhood, and work inside and outside the home, Lisa helps you uncover the key to living a busy life with inner calm. What's the secret? Identifying key priorities and doing first what matters most.With humor and wisdom, Lisa will help you:• Stop striving and rest in God's unconditional love.• Experience new hope in your marriage.• Reach your child's heart.• Create clarity in a cluttered home.• Find friendships that go below the surface and satisfy.• Discover your passion and purpose.Once in a while, things may seem as if they're under control, but we want to walk with purpose regardless of our circumstances. God wants us to daily experience the joy and contentment that comes from knowing we have given our all to what he considers most important. The abundant and purposeful life we were created to live is just around the corner.