In Victoria Costello's family mental illness had been given many names over at least four generations until this inherited conspiracy of silence finally endangered the youngest members of the family, her children.In this riveting story--part memoir, detective story, and scientific investigation--in the tradition of the story of Henrietta Lacks, Costello recounts how the mental unraveling of her seventeen-year-old son Alex compelled her to look back into family history for clues to his condition. Eventually she tied Alex's descent into hallucinations and months of shoeless wandering on the streets of Los Angeles to his great grandfather's suicide on a New York City railroad track in 1913.But this insight brought no quick relief. Within two years of Alex's diagnosis of paranoid schizophrenia, both she and her youngest son succumbed to two different mental disorders: major depression and anxiety disorder. Costello depicts her struggle to get the best possible mental health care for her sons and herself, treatment that ultimately brings each of them to full recovery. In the process, she discovers startling new neuroscience and genetic findings that explain how clusters of mental illness traverse family generations.The author closes by translating what she's learned into a set of ground rules for "New, New Parenting," advice to help individuals and families recover from addictions and mental disorders, and prevent their return in future generations.

    But Cullen was no mercy killer, nor was he a simple monster. He was a favorite son, husband, beloved father, best friend, and celebrated caregiver. Implicated in the deaths of as many as 300 patients, he was also perhaps the most prolific serial killer in American history.Cullen's murderous career in the world's most trusted profession spanned sixteen years and nine hospitals across New Jersey and Pennsylvania. When, in March of 2006, Charles Cullen was marched from his final sentencing in an Allentown, Pennsylvania, courthouse into a waiting police van, it seemed certain that the chilling secrets of his life, career, and capture would disappear with him. Now, in a riveting piece of investigative journalism nearly ten years in the making, journalist Charles Graeber presents the whole story for the first time. Based on hundreds of pages of previously unseen police records, interviews, wire-tap recordings and videotapes, as well as exclusive jailhouse conversations with Cullen himself and the confidential informant who helped bring him down, THE GOOD NURSE weaves an urgent, terrifying tale of murder, friendship, and betrayal.Graeber's portrait of Cullen depicts a surprisingly intelligent and complicated young man whose promising career was overwhelmed by his compulsion to kill, and whose shy demeanor masked a twisted interior life hidden even to his family and friends. Were it not for the hardboiled, unrelenting work of two former Newark homicide detectives racing to put together the pieces of Cullen's professional past, and a fellow nurse willing to put everything at risk, including her job and the safety of her children, there's no telling how many more lives could have been lost.In the tradition of In Cold Blood, THE GOOD NURSE does more than chronicle Cullen's deadly career and the breathless efforts to stop him; it paints an incredibly vivid portrait of madness and offers a penetrating look inside America's medical system. Harrowing and irresistibly paced, this book will make you look at medicine, hospitals, and the people who work in them, in an entirely different way.

    These and other sensational cases featured in this provacative book make for true-crime and medical detection at its most authentic and compelling--a must read for anyone interested in the truth behind the headlines.

    Keith Block is at the global vanguard of innovative cancer care. As medical director of the Block Center for Integrative Cancer Treatment in Evanston, Illinois, he has treated thousands of patients who have lived long, full lives beyond their original prognoses. Now he has distilled almost thirty years of experience into the first book that gives patients a systematic, research-based plan for developing the physical and emotional vitality they need to meet the demands of treatment and recovery.Based on a profound understanding of how body and mind can work together to defeat disease, this groundbreaking book offers:- Innovative approaches to conventional treatments, such as "chronotherapy"-chemotherapy timed to patients' unique circadian rhythms for enhanced effectiveness and reduced toxicity- Dietary choices that make the biochemical environment hostile to cancer growth and recurrence, and strengthen the immune system's ability to attack remaining cancer cells- Precise supplement protocols to tame treatment side effects, relieve disease-related symptoms, and modify processes like inflammation and glycemia that can fuel cancer if left untreated- A new paradigm for exercise and stress reduction that restores your strength, reduces anxiety and depression, and supports the body's own ability to heal- A complete program for remission maintenance-a proactive plan to make sure the cancer never returnsAlso included are "quick-start" maps to help you find the information you need right now and many case histories that will support and inspire you. Encouraging, compassionate, and authoritative, Life over Cancer is the guide patients everywhere have been waiting for.

    It infected nearly one-third of the world’s population and killed ten percent of those it struck. In its wake, schools and businesses closed, hospitals became overwhelmed, and the sick spilled out into makeshift care centers in public spaces. Policemen, public transportation workers, and everyday citizens in face masks were a common—and eerie—sight. Yet, discussion of this global pandemic often takes a backseat to World War I and other contemporary events.

    But Max Leonard, himself an accomplished amateur cyclist, does not forget the pain, the glory, the sweat, and the tears that go into these grueling climbs.  After all, cycling up a mountain is hard.  So hard that, to many, it can seem absurd. But for others, climbing a mountain gracefully (and beating your competitors up the slope) represents the pinnacle of cycling achievement. It is where legends are forged.Many books tell you where the mountains are, or how long and how high. None of them ask why. Why are mountain ranges professional cycling’s Coliseum? Why do amateurs also make pilgrimages to these high, remote roads? Why are the roads even there in the first place to lure us on to these obsession inducing climbs?   Just why are mountains so enthralling? “This is real cycling, where the glory is and where dreams come true,” according to Bradley Wiggins. Mountains are where cycling's greatest heroes have made their names. Every amateur rider wishes they could climb better, too.  Are all these people addicted to the pain? To the achievement? Or to the allure of the peaks? Some spend their weekends and holidays cycling up mountains from start to finish. But how does a rider push themselves beyond their limits to get up a 10% gradient on pedal power alone? What is happening when they do?A Higher Calling explores the central place of mountains in the folklore of road cycling. Blending adventure and travel writing with the rich narrative of racing, Max Leonard takes the reader from the battles that created the Alpine roads to the shepherds tending their flocks on the peaks, and to a Grand Tour climax on the “highest road in Europe.” And he tells stories of courage and sacrifice, war and love, obsession and even elephants, along the way.

    That's a lot to pin on a simple molecule.But your testosterone level doesn't actually predict your competitive drive, appetite for risk, sex drive, strength, or athletic prowess. It isn't the biological essence of manliness--in fact, it isn't even a male sex hormone. So what is it, and how did we come to endow it with such superhuman powers? This unauthorized biography pries the much-maligned T free from over a century of misconceptions.Testosterone's story begins long before the hormone was even isolated, when scientists first went looking for the chemical essence of masculinity. Over time, this molecule provided a handy rationale for countless behaviors--from the boorish to the enviable. Today, as competitive athletes turn to testosterone for competitive advantage, and we continue to debate what it means to be a man or woman, it is back in the news again. What we think we know about has stood in the way of an accurate understanding of its surprising functions and effects. Rebecca Jordan-Young and Katrina Karkazis focus on what testosterone does in six domains: reproduction, aggression, risk-taking, power, sports, and parenting. and let us us see the real testosterone for the first time.

    These are the very same behaviors that typify good soldiering and foster a sense of belonging among troops, whether they’re fighting on the front lines or engaged in non-combat activities away from the action. Drawing from history, psychology, and anthropology, bestselling author Sebastian Junger shows us just how at odds the structure of modern society is with our tribal instincts, arguing that the difficulties many veterans face upon returning home from war do not stem entirely from the trauma they’ve suffered, but also from the individualist societies they must reintegrate into.A 2011 study by the Canadian Forces and Statistics Canada reveals that 78 percent of military suicides from 1972 to the end of 2006 involved veterans. Though these numbers present an implicit call to action, the government is only just taking steps now to address the problems veterans face when they return home. But can the government ever truly eliminate the challenges faced by returning veterans? Or is the problem deeper, woven into the very fabric of our modern existence? Perhaps our circumstances are not so bleak, and simply understanding that beneath our modern guises we all belong to one tribe or another would help us face not just the problems of our nation but of our individual lives as well.Well-researched and compellingly written, this timely look at how veterans react to coming home will reconceive our approach to veteran’s affairs and help us to repair our current social dynamic.

    However, in a country of more than 325 million people, addressing everyone's issues is challenging. How can we effect beneficial change for everyone so we all can thrive? What is the great equalizer?In this book, Daniel E. Dawes argues that political determinants of health create the social drivers--including poor environmental conditions, inadequate transportation, unsafe neighborhoods, and lack of healthy food options--that affect all other dynamics of health. By understanding these determinants, their origins, and their impact on the equitable distribution of opportunities and resources, we will be better equipped to develop and implement actionable solutions to close the health gap.Dawes draws on his firsthand experience helping to shape major federal policies, including the Affordable Care Act, to describe the history of efforts to address the political determinants that have resulted in health inequities. Taking us further upstream to the underlying source of the causes of inequities, Dawes examines the political decisions that lead to our social conditions, makes the social determinants of health more accessible, and provides a playbook for how we can address them effectively. A thought-provoking and evocative account that considers both the policies we think of as health policy and those that we don't, The Political Determinants of Health provides a novel, multidisciplinary framework for addressing the systemic barriers preventing the United States from becoming the healthiest nation in the world.

    Too bad. Because medicine isn't an industry, it's practically witchcraft. Despite the growth of big pharma, HMOs, and hospital chains, medicine remains the isolated work of individual doctors—and the system is going broke fast.So why is Andy Kessler—the man who told you outrageous stories of Wall Street analysts gone bad in Wall Street Meat and tales from inside a hedge fund in Running Money—poking around medicine for the next big wave of technology?It's because he smells change coming. Heart attacks, strokes, and cancer are a huge chunk of medical spending, yet there's surprisingly little effort to detect disease before it's life threatening. How lame is that—especially since the technology exists today to create computer-generated maps of your heart and colon?Because it's too expensive—for now. But Silicon Valley has turned computing, telecom, finance, music, and media upside down by taking expensive new technologies and making them ridiculously cheap. So why not the $1.8 trillion health care business, where the easiest way to save money is to stop folks from getting sick in the first place?Join Kessler's bizarre search for the next big breakthrough as he tries to keep from passing out while following cardiologists around, cracks jokes while reading mammograms, and watches twitching mice get injected with radioactive probes. Looking for a breakthrough, Kessler even selflessly pokes, scans, and prods himself.CT scans of your heart will identify problems before you have a heart attack or stroke; a nanochip will search your blood for cancer cells--five years before they grow uncontrollably and kill you; and baby boomers can breathe a little easier because it's all starting to happen now.Your doctor can't be certain what's going on inside your body, but technology will. Embedding the knowledge of doctors in silicon will bring a breakout technology to health care, and we will soon see an end of medicine as we know it.

    Lisa Sanders, author of the monthly New York Times Magazine column "Diagnosis," the inspiration for the hit Fox TV series House, M.D.The experience of being ill can be like waking up in a foreign country. Life, as you formerly knew it, is on hold while you travel through this other world as unknown as it is unexpected. When I see patients in the hospital or in my office who are suddenly, surprisingly ill, what they really want to know is, ‘What is wrong with me?’ They want a road map that will help them manage their new surroundings. The ability to give this unnerving and unfamiliar place a name, to know it–on some level–restores a measure of control, independent of whether or not that diagnosis comes attached to a cure. Because, even today, a diagnosis is frequently all a good doctor has to offer.A healthy young man suddenly loses his memory–making him unable to remember the events of each passing hour. Two patients diagnosed with Lyme disease improve after antibiotic treatment–only to have their symptoms mysteriously return. A young woman lies dying in the ICU–bleeding, jaundiced, incoherent–and none of her doctors know what is killing her. In Every Patient Tells a Story, Dr. Lisa Sanders takes us bedside to witness the process of solving these and other diagnostic dilemmas, providing a firsthand account of the expertise and intuition that lead a doctor to make the right diagnosis.Never in human history have doctors had the knowledge, the tools, and the skills that they have today to diagnose illness and disease. And yet mistakes are made, diagnoses missed, symptoms or tests misunderstood. In this high-tech world of modern medicine, Sanders shows us that knowledge, while essential, is not sufficient to unravel the complexities of illness. She presents an unflinching look inside the detective story that marks nearly every illness–the diagnosis–revealing the combination of uncertainty and intrigue that doctors face when confronting patients who are sick or dying. Through dramatic stories of patients with baffling symptoms, Sanders portrays the absolute necessity and surprising difficulties of getting the patient’s story, the challenges of the physical exam, the pitfalls of doctor-to-doctor communication, the vagaries of tests, and the near calamity of diagnostic errors. In Every Patient Tells a Story, Dr. Sanders chronicles the real-life drama of doctors solving these difficult medical mysteries that not only illustrate the art and science of diagnosis, but often save the patients’ lives.

    Backed by investors such as Larry Ellison and Tim Draper, Theranos sold shares in a fundraising round that valued the company at $9 billion, putting Holmes's worth at an estimated $4.7 billion. There was just one problem: The technology didn't work.For years, Holmes had been misleading investors, FDA officials, and her own employees. When Carreyrou, working at The Wall Street Journal, got a tip from a former Theranos employee and started asking questions, both Carreyrou and the Journal were threatened with lawsuits. Undaunted, the newspaper ran the first of dozens of Theranos articles in late 2015. By early 2017, the company's value was zero and Holmes faced potential legal action from the government and her investors. Here is the riveting story of the biggest corporate fraud since Enron, a disturbing cautionary tale set amid the bold promises and gold-rush frenzy of Silicon Valley.

    His influence on 20th-century thinking and issues is arguably unparalleled, affecting attitudes on sex, religion, art, culture, and more. Written for the layperson, Freud for Beginners explains the doctor's dogma with wit and clarity, all in a contemporary context.

    It's extremely selfish to think we are the only existing intelligent life. Science and religion are on the verge of discovering the truth. Super ancient societies and their archaeological evidence uncovered to this day is a vault of stored information waiting to be unlocked. All we need to do is find the key. Help us uncover the truth by learning about Ancient Earth Mysteries.

    She entered Ah-gwah-ching State Sanatorium at Walker, Minnesota, for what she thought would be a short stay. In January, her tuberculosis spread, and she nearly died. Her recovery required many months of bed rest and medical care.Marilyn loved to write, and the story of her three-year residency at the sanatorium is preserved in hundreds of letters that she mailed back home to her parents, who could visit her only occasionally and whom she missed terribly. The letters functioned as a diary in which Marilyn articulately and candidly recorded her reactions to roommates, medical treatments, Native American nurses, and boredom. She also offers readers the singular perspective of a bed-bound teenager, gossiping about boys, requesting pretty new pajamas, and enjoying Friday evening popcorn parties with other patients.Selections from this cache of letters are woven into an informative narrative that explores the practices and culture of a midcentury tuberculosis sanatorium and fills in long-forgotten details gleaned from recent conversations with Marilyn, who "graduated" from the sanatorium and went on to lead a full, productive life.