At his death last spring, Roueche left behind seven new narratives that have never been published in book form. This book collects these works along with one earlier classic--all relating true tales of strange illnesses, rare diseases, and the brilliant minds who race to understand and conquer them.

    But what if everything we’ve been taught to believe about aging is wrong? What if we could choose our lifespan? In this groundbreaking book, Dr. David Sinclair, leading world authority on genetics and longevity, reveals a bold new theory for why we age. As he writes: “Aging is a disease, and that disease is treatable.” This book takes us to the frontlines of research many from Dr. David Sinclair’s own lab at Harvard—that demonstrate how we can slow down, or even reverse, aging. The key is activating newly discovered vitality genes, the descendants of an ancient genetic survival circuit that is both the cause of aging and the key to reversing it.

    In these incisive and provocative essays, Suzuki looks unflinchingly at the destructive forces of globalization, political short-sightedness, and greed. Suzuki cautions against blind faith in science, technology, politics, and economics, and provides inspiring examples of how and where to make those changes that will matter to all of us and to future generations. In this time of global unrest and uncertainty, Suzuki provides an important reminder of how we are all connected and of what really matters. Written with clarity, passion, and wisdom, this book is essential reading for anyone who admires David Suzuki, who wants to understand what science can and can't do, or who wants to make a difference.Published in partnership with the David Suzuki Foundation.

    Optimism, courage, joy and spirituality were central to Leary's final days and his death. Design for Dying -- Leary's last book -- shows us how we too can make dying the high point of life. Irreverent, thought-provoking and hilarious, Leary's parting shot pioneers new ways to die and new ways for the living to think about death. Urging us to take control of our deaths (and even to determine when and how we will die), Leary relates his own plan for "directed dying," a death we plan and orchestrate to reflect our own lives and values.And the psychedelic prophet flings open a whole new range of beyond-death possibilites for the wired generation. From downloading consciousness onto the Net -- so that our souls can outlive our bodies -- to the way technology can enhance the final days of the dying to the far-out promises of cryogenics, Leary provides fascinating insights into how technology may eventually help us improve, and even sidestep, death. A thorough guide to death and dying resources and to online tools and further reading lists completes this surprising, funny and totally original look at the new frontiers of death.Speaking to everyone who has ever wondered if there's more to death - -if there's life beyond the final frontier, if death really means the end, if dirges and hearses and funeral flowers are really how we want to be remembered -- Leary's flamboyant final statement rteveals revolutionary ways to die and redefines, with Leary's trademark creativity and joy, how the living can think about death.

    Si todos debemos movernos para sobrevivir, vale la pena preguntarse: ¿qué factores de nuestro entorno nos impulsan a movernos y cuáles, por el contrario, nos detienen? ¿Por qué algunas personas tienen la oportunidad de moverse hacia donde quieren y otras no? ¿Por qué ciertas sociedades evolucionan y otras no? Para responder a estas interrogantes, los autores del libro estudiaron los códigos culturales y el comportamiento Bio-Lógico de 71 países para desarrollar un índice de que permite medir la movilidad social dentro de estas sociedades.Andrés Roemer y Clotaire Rapaille señalan que las culturas más exitosas son aquellas que han sabido preservar los mejores aspectos de su tradición, al mismo tiempo que han estado dispuestas a innovar y buscar nuevos horizontes. Se trata de sociedades abiertas al cambio y sin temor al statu quo. Otra clave del éxito evolutivo de las sociedades es el equilibrio entre el aspecto biológico (determinado por cuatro factores: supervivencia, sexo, seguridad y superación) y el aspecto cultural. El reto, concluyen los autores, es aprender a armonizar nuestros instintos (nuestro cerebro reptiliano) con nuestras emociones (nuestro cerebro límbico) y nuestra lógica (el neocórtex).ENGLISH DESCRIPTION If we all know we must move to survive, shouldn’t we ask ourselves which factors in our environment propel us and which halt us? Why do certain societies evolve while others don’t? In this book, Andrés Roemer and Clotaire Rapaille point out that the most successful cultures are those that are not afraid of the status quo: they have learned to preserve the best qualities of their traditions while being open to innovation and to uncovering new horizons. Another key to the success of these societies is the equilibrium between biological and the cultural aspects. The challenge is to harmonize our instincts, our emotions, and our logic.

    You see the smokers, the overeaters, the bottle-feeders, and affirm your own health in the process. In these and countless other instances, the perception of your own health depends in part on your value judgments about others, and appealing to health allows for a set of moral assumptions to fly stealthily under the radar.Against Health argues that health is a concept, a norm, and a set of bodily practices whose ideological work is often rendered invisible by the assumption that it is a monolithic, universal good. And, that disparities in the incidence and prevalence of disease are closely linked to disparities in income and social support. To be clear, the book's stand against health is not a stand against the authenticity of people's attempts to ward off suffering. Against Health instead claims that individual strivings for health are, in some instances, rendered more difficult by the ways in which health is culturally configured and socially sustained.The book intervenes into current political debates about health in two ways. First, Against Health compellingly unpacks the divergent cultural meanings of health and explores the ideologies involved in its construction. Second, the authors present strategies for moving forward. They ask, what new possibilities and alliances arise? What new forms of activism or coalition can we create? What are our prospects for well-being? In short, what have we got if we ain't got health? Against Health ultimately argues that the conversations doctors, patients, politicians, activists, consumers, and policymakers have about health are enriched by recognizing that, when talking about health, they are not all talking about the same thing. And, that articulating the disparate valences of "health" can lead to deeper, more productive, and indeed more healthy interactions about our bodies.

    Pulitzer Prize–winning author Siddhartha Mukherjee, a leading cancer physician and researcher, selects the year’s top science and nature writing from journalists who dive into their fields with curiosity and passion, delivering must-read articles from a wide array of fields.

    Over the past few decades there has been a revolution in terms of who controls knowledge and information. This rapid change has imperiled the way we think. Without pausing to consider the cost, the world has rushed to embrace the products and services of four titanic corporations. We shop with Amazon; socialize on Facebook; turn to Apple for entertainment; and rely on Google for information. These firms sell their efficiency and purport to make the world a better place, but what they have done instead is to enable an intoxicating level of daily convenience. As these companies have expanded, marketing themselves as champions of individuality and pluralism, their algorithms have pressed us into conformity and laid waste to privacy. They have produced an unstable and narrow culture of misinformation, and put us on a path to a world without private contemplation, autonomous thought, or solitary introspection--a world without mind. In order to restore our inner lives, we must avoid being coopted by these gigantic companies, and understand the ideas that underpin their success.Elegantly tracing the intellectual history of computer science--from Descartes and the enlightenment to Alan Turing to Stuart Brand and the hippie origins of today's Silicon Valley--Foer exposes the dark underpinnings of our most idealistic dreams for technology. The corporate ambitions of Google, Facebook, Apple, and Amazon, he argues, are trampling longstanding liberal values, especially intellectual property and privacy. This is a nascent stage in the total automation and homogenization of social, political, and intellectual life. By reclaiming our private authority over how we intellectually engage with the world, we have the power to stem the tide.At stake is nothing less than who we are, and what we will become. There have been monopolists in the past but today's corporate giants have far more nefarious aims. They're monopolists who want access to every facet of our identities and influence over every corner of our decision-making. Until now few have grasped the sheer scale of the threat. Foer explains not just the looming existential crisis but the imperative of resistance.

    And we know that another global disaster is eventually headed our way. Can we survive it? How?As a species, Homo sapiens is at a crossroads. Study of our planet’s turbulent past suggests that we are overdue for a catastrophic disaster, whether caused by nature or by human interference.It’s a frightening prospect, as each of the Earth’s past major disasters—from meteor strikes to bombardment by cosmic radiation—resulted in a mass extinction, where more than 75 percent of the planet’s species died out. But in Scatter, Adapt, and Remember, Annalee Newitz, science journalist and editor of the science Web site io9.com explains that although global disaster is all but inevitable, our chances of long-term species survival are better than ever. Life on Earth has come close to annihilation—humans have, more than once, narrowly avoided extinction just during the last million years—but every single time a few creatures survived, evolving to adapt to the harshest of conditions.      This brilliantly speculative work of popular science focuses on humanity’s long history of dodging the bullet, as well as on new threats that we may face in years to come. Most important, it explores how scientific breakthroughs today will help us avoid disasters tomorrow. From simulating tsunamis to studying central Turkey’s ancient underground cities; from cultivating cyanobacteria for “living cities” to designing space elevators to make space colonies cost-effective; from using math to stop pandemics to studying the remarkable survival strategies of gray whales, scientists and researchers the world over are discovering the keys to long-term resilience and learning how humans can choose life over death.     Newitz’s remarkable and fascinating journey through the science of mass extinctions is a powerful argument about human ingenuity and our ability to change. In a world populated by doomsday preppers and media commentators obsessively forecasting our demise, Scatter, Adapt, and Remember is a compelling voice of hope. It leads us away from apocalyptic thinking into a future where we live to build a better world—on this planet and perhaps on others. Readers of this book will be equipped scientifically, intellectually, and emotionally to face whatever the future holds.

    It is high time for humanity to grow up and to transcend itself by embracing transhumanism.Transhumanism offers the most inclusive ideology for all ethnicities and races, the religious and the atheists, conservatives and liberals, the young and the old regardless of socioeconomic status, gender identity, or any other individual qualities. This book expounds on contemporary views and practical advice from more than 70 transhumanists.Astronaut Neil Armstrong said on the Apollo 11 moon landing in 1969, "One small step for a man, one giant leap for mankind." Transhumanism is the next logical step in the evolution of humankind, and it is the existential solution to the long-term survival of the human race.

    Conscious Robots challenges us to face up to the reality of being human: just because we're conscious doesn't mean we're not robots. So what would we do with free will if we really had it? And how does “being a robot” explain why life, as Buddha suggested, is “inherently unsatisfactory”, despite our luxurious homes, successful careers and loving families? Conscious Robots shows why we’re so convinced that we’re in charge, when we’re really just carrying out our evolved pre-programmed instructions. And reveals the inevitable future, how one day humans will take control of their conscious minds, get happy and stay happy. But it will come too late for you, Dear Reader… so no point buying the book. Unless you’re extremely rich, of course. Then you can pay for the neurochemical research yourself. “Easy to understand and persuasive” “Reminded me of Douglas Adams and Terry Pratchett”

    According to Stewart Brand, a lifelong environmentalist who sees everything in terms of solvable design problems, three profound transformations are underway on Earth right now. Climate change is real and is pushing us toward managing the planet as a whole. Urbanization--half the world's population now lives in cities, and eighty percent will by midcentury--is altering humanity's land impact and wealth. And biotechnology is becoming the world's dominant engineering tool. In light of these changes, Brand suggests that environmentalists are going to have to reverse some longheld opinions and embrace tools that they have traditionally distrusted. Only a radical rethinking of traditional green pieties will allow us to forestall the cataclysmic deterioration of the earth's resources.Whole Earth Discipline shatters a number of myths and presents counterintuitive observations on why cities are actually greener than the countryside, how nuclear power is the future of energy, and why genetic engineering is the key to crop and land management. With a combination of scientific rigour and passionate advocacy, Brand shows us exactly where the sources of our dilemmas lie and offer a bold and inventive set of policies and solutions for creating a more sustainable society. In the end, says Brand, the environmental movement must become newly responsive to fast-moving science and take up the tools and discipline of engineering. We have to learn how to manage the planet's global-scale natural infrastructure with as light a touch as possible and as much intervention as necessary.

    But philosopher and cognitive scientist Andy Clark sees it differently. Cyborgs, he writes, are not something to be feared--we already are cyborgs. In Natural-Born Cyborgs, Clark argues that what makes humans so different from other species is our capacity to fully incorporate tools and supporting cultural practices into our existence. Technology as simple as writing on a sketchpad, as familiar as Google or a cellular phone, and as potentially revolutionary as mind-extending neural implants--all exploit our brains' astonishingly plastic nature. Our minds are primed to seek out and incorporate non-biological resources, so that we actually think and feel through our best technologies. Drawing on his expertise in cognitive science, Clark demonstrates that our sense of self and of physical presence can be expanded to a remarkable extent, placing the long-existing telephone and the emerging technology of telepresence on the same continuum. He explores ways in which we have adapted our lives to make use of technology (the measurement of time, for example, has wrought enormous changes in human existence), as well as ways in which increasingly fluid technologies can adapt to individual users during normal use. Bio-technological unions, Clark argues, are evolving with a speed never seen before in history. As we enter an age of wearable computers, sensory augmentation, wireless devices, intelligent environments, thought-controlled prosthetics, and rapid-fire information search and retrieval, the line between the user and her tools grows thinner day by day. This double whammy of plastic brains and increasingly responsive and well-fitted tools creates an unprecedented opportunity for ever-closer kinds of human-machine merger, he writes, arguing that such a merger is entirely natural. A stunning new look at the human brain and the human self, Natural Born Cyborgs reveals how our technology is indeed inseparable from who we are and how we think.

    With living proof that such advancements are no longer the stuff of science fiction, a whole new world of possibilities--and dangers--presented itself. Jeremy Rifkin is more concerned with the dangers of this technology, and in The Biotech Century , he presents numerous compelling reasons why we should be, too. Many of these dangers revolve around the seemingly inevitable commercialization of genetically engineered life forms that would come if corporations battled for the rights to patents on new or modified species of plants, animals, or even human beings. Rifkin warns that "designer" babies and genetically perfect humans, along with any other artificial creations, would wreak havoc with the gene pool and the natural environment. While he concedes that there are benefits to biotechnology, he makes it clear that the risks far outweigh the rewards at this time, urging for greater restraint and responsibility before opening what could be a Pandora's box.

    The book has undergone three editions, several reprints, and revised reprints in a span of 13 years. There are many biochemistry textbooks in the market. Some of them are purely basic while others are applied, and there are very few books which cover both these aspects together. For this reason, the students learning biochemistry in their undergraduate courses have to depend on multiple books to acquire a sound knowledge of the subject. This book, ‘Biochemistry’ is unique with a simultaneous and equal emphasis on basic and applied aspects of biochemistry. This textbook offers an integration of medical and pure sciences, comprehensively written to meet the curriculum requirements of undergraduate courses in medical, dental, pharmacy, life-sciences and other categories (agriculture, veterinary, etc.). This book is designed to develop in students a sustained interest and enthusiasm to learn and develop the concepts in biochemistry in a logical and stepwise manner. It incorporates a variety of pedagogic aids, besides colour illustrations to help the students understand the subject quickly and to the maximum. The summary and biomedical/clinical concepts are intended for a rapid absorption and assimilation of the facts and concepts in biochemistry. The self-assessment exercises will stimulate the students to think rather than merely learn the subject. In addition, these exercises (essays, short notes, fill in the blanks, multiple choice questions) set at different difficulty levels, will cater to the needs of all the categories of learners.New to This Edition The book offers an integration of medical and pure sciences, and is comprehensively written, revised and updated to meet the curriculum requirements of Medical, Pharmacy, Dental, Veterinary, Biotechnology, Agricultural Sciences, Life Sciences, and others studying Biochemistry as one of the subjects. It is the first text book on Biochemistry in English with multi-colour illustrations by an author from Asia. The use of multicolours is for a clearer understanding of the complicated biochemical reactions. It is written in a lucid style with the subject being presented as an engaging story growing from elementary information to the most recent advances, and with theoretical discussions being supplemented with illustrations, flowcharts, and tables for easy understanding of Biochemistry. It has each chapter beginning with a four-line verse followed by the text, biomedical concepts, a summary, and self-assessment exercises. The lively illustrations and text with appropriate headings and sub-headings in bold type faces facilitate reading path clarity and quick recall. It provides the most recent and essential information on Molecular Biology and Biotechnology, Diabetes, Cancer, Free Radicals, Free radicals and Antioxidants, Prostaglandins, etc. It describes a wide variety of case studies and biochemical correlations and several newer biomedical aspects- Metabolic syndrome, Therapeutic diets, Atkins diet, Trans fatty acids, Epigenetics, Nutrigenomics, Recombinant ribozymes, Membrane transport disorders, Pleural fluid etc. It contains the basics (Bioorganic and Biophysical Chemistry, Tools of Biochemistry, Immunology, and Genetics) for beginners to learn easily Biochemistry, origins of biochemical words, confusables in Biochemistry, principles of Practical Biochemistry, and Clinical Biochemistry Laboratory.