That nation did not exist when, in the mid-19th century, Europeans first began to explore the possibilities of creating a link between the Atlantic and Pacific oceans through the narrow but mountainous isthmus; Panama was then a remote and overlooked part of Colombia.All that changed, writes David McCullough in his magisterial history of the Canal, in 1848, when prospectors struck gold in California. A wave of fortune seekers descended on Panama from Europe and the eastern United States, seeking quick passage on California-bound ships in the Pacific, and the Panama Railroad, built to serve that traffic, was soon the highest-priced stock listed on the New York Exchange. To build a 51-mile-long ship canal to replace that railroad seemed an easy matter to some investors. But, as McCullough notes, the construction project came to involve the efforts of thousands of workers from many nations over four decades; eventually those workers, laboring in oppressive heat in a vast malarial swamp, removed enough soil and rock to build a pyramid a mile high. In the early years, they toiled under the direction of French entrepreneur Ferdinand de Lesseps, who went bankrupt while pursuing his dream of extending France's empire in the Americas. The United States then entered the picture, with President Theodore Roosevelt orchestrating the purchase of the canal—but not before helping foment a revolution that removed Panama from Colombian rule and placed it squarely in the American camp.

    In all the current highly publicized debates about creationism and its descendant "intelligent design," there is an element of the controversy that is rarely mentioned—the "evidence," the empirical truth of evolution by natural selection. Even Richard Dawkins and Stephen Jay Gould, while extolling the beauty of evolution and examining case studies, have not focused on the evidence itself. Yet the proof is vast, varied, and magnificent, drawn from many different fields of science. Scientists are observing species splitting into two and are finding more and more fossils capturing change in the past—dinosaurs that have sprouted feathers, fish that have grown limbs. Why Evolution Is True weaves together the many threads of modern work in genetics, paleontology, geology, molecular biology, and anatomy that demonstrate the "indelible stamp" of the processes first proposed by Darwin. In crisp, lucid prose accessible to a wide audience, Why Evolution Is True dispels common misunderstandings and fears about evolution and clearly confirms that this amazing process of change has been firmly established as a scientific truth.

    Craig Venter became the first to successfully create synthetic life putting humankind at the threshold of the most important and exciting phase of biological research, one that will enable us to actually write the genetic code for designing new species to help us adapt and evolve for long-term survival. The science of synthetic genomics will have a profound impact on human existence, including chemical and energy generation, health, clean water and food production, environmental control, and possibly even our evolution. In "Life at the Speed of Light," Venter presents a fascinating and authoritative study of this emerging field from the inside detailing its origins, current challenges and controversies, and projected effects on our lives. This scientific frontier provides an opportunity to ponder anew the age-old question What is life? and examine what we really mean by playing God. " Life at the Speed of Light "is a landmark work, written by a visionary at the dawn of a new era of biological engineering."

    Who knew that he also was a pivotal figure in the development of the airplane, the hydrofoil, genetic engineering, and more? Charlotte Gray does, and she tells us how and why she brought to life the passionate mind and heart of the man behind so many amazing ideas and innovations. --Lauren Nemroff Some Questions for Charlotte Gray [image] 1. Most people picture Alexander Graham Bell as that grandfatherly looking man with a long white beard who invented the telephone. What's wrong with that image? The image of Alexander Graham Bell as a kindly Santa Claus figure is the one we all know: It is as familiar as the one of Einstein with his hair in a frizzy grey mass. But when Alexander Graham Bell was struggling to invent the telephone, he was a skinny, clean-shaven, neurotically intense young man and a hypochondriac, with obsessive work habits and a very volatile nature. Reading his letters and journals, I was shocked to discover how often he would ricochet between euphoria and depression. Invention was Alexander Graham Bell's passion, but I frequently wondered whether, if he had not had an early success and the right wife, his difficult personality would have prevented him achieving anything. I think it is important to revise the grandfatherly stereotype of Bell in order to show that invention is difficult, and inventors are not easy, placid people to live with. 2. In what way does Bell's genius different from other inventors of his age, such as Thomas Edison or the Wright brothers? The wonderful thing about the inventions of such nineteenth century giants as Bell, Edison and the Wright brothers is that, with a little bit of effort, even those of us who never did Grade 12 physics can actually understand how their inventions worked. One could never say that about today's microelectronic technology. Intuition and imagination were all crucial for the breakthroughs made by Edison, the Wright brothers and Bell. However, what sets Bell apart from Edison and the Wright brothers was that he didn't have an entrepreneurial bone in his body. He was more like a holdover from the eighteenth century Enlightenment, while the others were go-getting twentieth-century hustlers. Edison was always looking for financial backers; he announced his breakthroughs before he had even built working prototypes; he was one of the first inventors to put together a real R and D team at a purpose-built laboratory, at Menlo Park. He understood that invention is, in his own words, "One percent inspiration, ninety percent perspiration." Similarly the Wright Brothers were eager to make money out of their flying machines. They refused to share their technological breakthroughs, guarded their patents fiercely, and wouldn't give any demonstrations to the public of their biplanes. Bell was the opposite--totally absorbed in extending the frontiers of knowledge, and completely careless about commercial exploitation of his ideas. 3. Is it true that "necessity is the mother of invention" or is it something else? Invention has many mothers - the right materials, a widespread understanding that this will improve the world in some way, the right individual to pursue the elusive dream. In the case of the telephone, one can argue that there was no overwhelming necessity for a new form of communication: the telegraph had been working well for 30 years, and only a few people realized that a device that could carry the human voice, rather than the Morse code, would pull people together in a revolutionary way. As soon as telephones appeared in the market, their advantages were obvious. But there was still incredible resistance. In Britain, the upper classes were slow to acquire telephones because they posed a class issue: who should answer them? Everybody knew that, in a house with servants, the servant answered the door when the telegraph boy rang the bell. But should master or servant speak on the phone? The democratic nature of the telephone--anybody could use it, not just qualified operators--also shackled its spread. In Russia after the revolution, Stalin is said to have vetoed the idea of a modern telephone system. "It will unmake our work," the dictator decreed. "No greater instrument for counter-revolution and conspiracy can be imagined." So did necessity drive the invention of the telephone? No--when Bell first started speculating on its impact, people thought he was mad. But it quickly became a total necessity…imagine life without electronic communication today! 4. It was amazing to learn that Bell's mother and his wife were both deaf, and that from an early age he was immersed in research on the nature of sound and oral communication. How important were these personal relationships in shaping his outlook and inventions? One of my greatest surprises when I started research for Reluctant Genius was the discovery that Bell's first ambition was to be a teacher of the deaf, and that he remained committed to the cause of improved education for the hearing impaired throughout his life. I had no idea of this side of him, or of his long relationship with Helen Keller. The fact that the two most important women in his life, his mother and his wife, were deaf was of crucial importance both to his own work, and to his attitude to others. His respect for their intelligences and personalities meant that, unlike many of his contemporaries, he never assumed that deafness was linked to intellectual disability. Moreover, his scientific interest in their condition informed his telephone research. Because he knew why their ears didn't work, he understood how sound should reach the brain in a hearing person's ear, through the ear drum. None of his competitors made that intuitive leap. Their early attempts to build working telephones were foiled because they didn't include the diaphragm that mimicked the action of the ear drum, and which was the key feature of Bell's first phone. Lastly, Bell was also fascinated by the intergenerational transmission of deafness. This led to his research on genetics in general - and the program he initiated at his summer home, in Cape Breton, to breed a flock of "super sheep" that would always have twin births. 5. Bell's wife, Mabel Hubbard Bell, was a remarkable person in her own right. Why was it so important to tell her story? Too often, biographies of "Great Men" suggest they achieved everything by their own efforts. A few did, of course, but most depended on the support and encouragement of others--parents, partners, associates--to provide the right environment in which they could achieve their goals. Behind every great man….This was the case with Alexander Graham Bell. He would always have had his "Eureka Moment", in the summer of 1874, when he realized how a "talking telegraph" might work. But without Mabel, we probably would never have heard of him. He would not have patented the invention or found the business partners who helped him moved his invention from the laboratory to the market place. Mabel's father, Gardiner Hubbard, was his patent lawyer: Mabel herself ensured that he went to the Philadelphia Exposition, in 1876, to demonstrate his new apparatus. In later years, Mabel provided all kinds of other practical help, in ensuring that her exasperating husband could focus on his inventions. She handled the financial side of their marriage: she found qualified young men who could help him work on his flying machines: she was always cheering him up and stroking his ego when he got depressed. And she created, along with their two daughters, a warm family environment which gave balance to Bell's life - and which so many of his contemporaries, including Thomas Edison, never enjoyed. I was determined to give Mabel her due in the story of Bell. I found her such an attractive and intriguing figure. She was stone deaf, ten years younger than her husband, and their relationship began as a teacher-student one. It would be easy to assume that this brilliant, world famous man would be the dominant figure in the relationship. In fact, the reverse is true. 6. What do you think Bell would think of cell phones, the internet and other wireless means of communication? Bell himself anticipated "electric communication": he was very frustrated by how long it took for a letter from Nova Scotia to reach Europe. I'm sure he would be delighted by the internet. However, he would be appalled by the constant buzz of other technological advances, and the way we've allowed them to trump all other forms of human intercourse. This is a man who wouldn't have a telephone in his own study, because its ring would disturb his train of thought. He was a gracious, well-mannered man who would have been horrified by the way many of us let our cell phones to interrupt our face-to-face conversations. And if somebody pulled out a Blackberry and started punching into it while Bell was speaking of him--well, Alec would have muttered, "Shee-e-esh" (the nearest he ever got to swearing) and stomped out of the room. 7. What was the most exciting research discovery that you made? As a biographer, I have to say that my most exciting discovery was the wealth of material I had to work with. Because Alexander Graham Bell could never speak to his wife on the telephone, he and Mabel exchanged long, intimate, colourful letters whenever they were apart--and that was often. I was thrilled to discover, at the Alexander Graham Bell Historic Site in Baddeck, Nova Scotia, 180 three-ring binders of family correspondence (another set is housed at the Library of Congress, Washington.) These letters let me explore the inner-workings of the mind of a genius, and of a remarkable marriage, in a way that I had hardly dared hope for. I was also amazed at the range of Bell's activities. The telephone, the photophone (which sent sounds down beams of light), an early iron lung, a desalination process for salt water, flying machines, hydrofoils, genetic experiments…his scientific interests were enormously varied. And at the same time, he was doing so much else, for example with the Smithsonian Institute, and the National Geographic Society. And throughout his career, there was his long-running commitment to deaf education. It was hard not to be overwhelmed! 8. What are you working on right now? Yes, I'm already launched on my next biography. (In fact, I find it very hard not to start my next book before the previous one is even in the stores--I have a psychological need to live both my own life and someone else's!) My next project is a short biography of Nellie McClung, the Canadian author and political activist.

    Sharon Moalem turns our current understanding of illness on its head and challenges us to fundamentally change the way we think about our bodies, our health, and our relationship to just about every other living thing on earth, from plants and animals to insects and bacteria.Through a fresh and engaging examination of our evolutionary history, Dr. Moalem reveals how many of the conditions that are diseases today actually gave our ancestors a leg up in the survival sweepstakes. When the option is a long life with a disease or a short one without it, evolution opts for disease almost every time.Everything from the climate our ancestors lived in to the crops they planted and ate to their beverage of choice can be seen in our genetic inheritance. But Survival of the Sickest doesn't stop there. It goes on to demonstrate just how little modern medicine really understands about human health, and offers a new way of thinking that can help all of us live longer, healthier lives..

    But the so-called Dark Ages also gave us the first universities, eyeglasses, and mechanical clocks, proving that the Middle Ages were home to a vibrant scientific culture.In The Light Ages, Cambridge science historian Seb Falk takes us on an immersive tour of medieval science through the story of one fourteenth-century monk, John of Westwyk. From multiplying Roman numerals to navigating by the stars, curing disease, and telling time with an ancient astrolabe, we learn emerging science alongside Westwyk, while following the gripping story of the struggles and successes of an ordinary man in a precarious world. An enlightening history that argues that these times weren’t so dark after all, The Light Ages shows how medieval ideas continue to color how we see the world today.

    This book reveals the most exhilarating oddities from Professor Stewart's legendary cabinet.Inside, you will find hidden gems of logic, geometry, and probability-like how to extract a cherry from a cocktail glass (harder than you think), a pop-up dodecahedron, and the real reason why you can't divide anything by zero. Scattered among these are keys to Fermat's last theorem, the Poincaréonjecture, chaos theory, and the P=NP problem (you'll win a million dollars if you solve it). You never know what enigmas you'll find in the Stewart cabinet, but they're sure to be clever, mind-expanding, and delightfully fun.

    organized crime for a bloody half century, there was the one-fingered criminal genius Giuseppe Morello–known as “The Clutch Hand”–and his lethal coterie of associates. In The First Family, historian, journalist, and New York Times bestselling author Mike Dash brings to life this little-known story, following the rise of the Mafia in America from the 1890s to the 1920s, from the lawless villages of Sicily to the streets of Little Italy. Using an impressive array of primary sources–hitherto untapped Secret Service archives, prison records, trial transcripts, and interviews with surviving family members–this is the first Mafia history that applies scholarly rigor to the story of the Morello syndicate and the birth of organized crime on these shores.Progressing from small-time scams to counterfeiting rings to even bigger criminal enterprises, Giuseppe Morello exerted ruthless control of Italian neighborhoods in New York, and through adroit coordination with other Sicilian crime families, his Clutch Hand soon reached far beyond the Hudson River.The men who battled Morello’s crews were themselves colorful and legendary figures, including William Flynn, a fearless Secret Service agent, and Lieutenant Detective Giuseppe “Joe” Petrosino of the New York Police Department’s elite Italian Squad, whose pursuit of the brutal gangs ultimately cost him his life. Combining first-rate scholarship and pulse-quickening action, and set amid rustic Sicilian landscapes and the streets of old New York, The First Family is a groundbreaking account of the crucial period when the American criminal underworld exploded with violent fury across the nation.

    And we know that another global disaster is eventually headed our way. Can we survive it? How?As a species, Homo sapiens is at a crossroads. Study of our planet’s turbulent past suggests that we are overdue for a catastrophic disaster, whether caused by nature or by human interference.It’s a frightening prospect, as each of the Earth’s past major disasters—from meteor strikes to bombardment by cosmic radiation—resulted in a mass extinction, where more than 75 percent of the planet’s species died out. But in Scatter, Adapt, and Remember, Annalee Newitz, science journalist and editor of the science Web site io9.com explains that although global disaster is all but inevitable, our chances of long-term species survival are better than ever. Life on Earth has come close to annihilation—humans have, more than once, narrowly avoided extinction just during the last million years—but every single time a few creatures survived, evolving to adapt to the harshest of conditions.      This brilliantly speculative work of popular science focuses on humanity’s long history of dodging the bullet, as well as on new threats that we may face in years to come. Most important, it explores how scientific breakthroughs today will help us avoid disasters tomorrow. From simulating tsunamis to studying central Turkey’s ancient underground cities; from cultivating cyanobacteria for “living cities” to designing space elevators to make space colonies cost-effective; from using math to stop pandemics to studying the remarkable survival strategies of gray whales, scientists and researchers the world over are discovering the keys to long-term resilience and learning how humans can choose life over death.     Newitz’s remarkable and fascinating journey through the science of mass extinctions is a powerful argument about human ingenuity and our ability to change. In a world populated by doomsday preppers and media commentators obsessively forecasting our demise, Scatter, Adapt, and Remember is a compelling voice of hope. It leads us away from apocalyptic thinking into a future where we live to build a better world—on this planet and perhaps on others. Readers of this book will be equipped scientifically, intellectually, and emotionally to face whatever the future holds.

    From the Space Shuttle training toilet to a crash test of NASA’s new space capsule, Mary Roach takes us on the surreally entertaining trip into the science of life in space and space on Earth.

    None of these factors is either definitive or destiny. Otherwise, how to explain why Botswana has become one of the fastest growing countries in the world, while other African nations, such as Zimbabwe, the Congo, and Sierra Leone, are mired in poverty and violence? Daron Acemoglu and James Robinson conclusively show that it is man-made political and economic institutions that underlie economic success (or lack of it). Korea, to take just one of their fascinating examples, is a remarkably homogeneous nation, yet the people of North Korea are among the poorest on earth while their brothers and sisters in South Korea are among the richest. The south forged a society that created incentives, rewarded innovation, and allowed everyone to participate in economic opportunities. The economic success thus spurred was sustained because the government became accountable and responsive to citizens and the great mass of people. Sadly, the people of the north have endured decades of famine, political repression, and very different economic institutions—with no end in sight. The differences between the Koreas is due to the politics that created these completely different institutional trajectories. Based on fifteen years of original research Acemoglu and Robinson marshall extraordinary historical evidence from the Roman Empire, the Mayan city-states, medieval Venice, the Soviet Union, Latin America, England, Europe, the United States, and Africa to build a new theory of political economy with great relevance for the big questions of today, including:    - China has built an authoritarian growth machine. Will it continue to grow at such high speed and overwhelm the West?    - Are America’s best days behind it? Are we moving from a virtuous circle in which efforts by elites to aggrandize power are resisted to a vicious one that enriches and empowers a small minority?    - What is the most effective way to help move billions of people from the rut of poverty to prosperity? More philanthropy from the wealthy nations of the West? Or learning the hard-won lessons of Acemoglu and Robinson’s breakthrough ideas on the interplay between inclusive political and economic institutions? Why Nations Fail will change the way you look at—and understand—the world.

    Dozens died of radiation poisoning, fallout contaminated half the continent, and thousands fell ill.In Chernobyl, Serhii Plokhy draws on new sources to tell the dramatic stories of the firefighters, scientists, and soldiers who heroically extinguished the nuclear inferno. He lays bare the flaws of the Soviet nuclear industry, tracing the disaster to the authoritarian character of the Communist party rule, the regime's control over scientific information, and its emphasis on economic development over all else.Today, the risk of another Chernobyl looms in the mismanagement of nuclear power in the developing world. A moving and definitive account, Chernobyl is also an urgent call to action.

    A preeminent scholar, writer, and teacher, he has had a profound influence on millions of people. To him, mythology was the "song of the universe, the music of the spheres." With Bill Moyers, one of America's most prominent journalists, as his thoughtful and engaging interviewer, The Power Of Myth touches on subjects from modern marriage to virgin births, from Jesus to John Lennon, offering a brilliant combination of intelligence and wit.

    Weaving together the cosmos' history and our own in an expanding intellectual adventure story, Dark Matter and the Dinosaurs takes us from the mysteries of dark matter and our cosmic environment to the conditions for life on Earth.Sixty-six million years ago, an object the size of a city descended from space to crash into Earth, creating a cataclysm that killed off the dinosaurs, along with three-quarters of the other species on the planet. What was its origin? Randall proposes it was a comet that was dislodged from its orbit as the Solar System passed through a disk of dark matter that is embedded in the plane of the Milky Way. Her research challenges the usual assumptions about the simple nature of dark matter and demonstrates how scientists formulate and establish new ideas. In a sense, it might have been dark matter that killed the dinosaurs.With her unique and wide-ranging perspective, Randall connects dark matter to the history of the world in the broadest terms. Bringing in pop culture and social and political viewpoints, she shares with us the latest findings—established and speculative—regarding dark matter, the cosmos, the galaxy, asteroids, comets, and impacts, as well as life's development and extinctions. Randall makes clear how connected the planet is to the makeup of the Universe, but also how fragile our place in the Universe, which evolved over billions of years, might be.In this brilliant and fresh exploration of our cosmic environment, Professor Randall explains the underlying science of our world in the breathtaking tale of a Universe in which the small and the large, the visible and the hidden are intimately related. Dark Matter and the Dinosaurs illuminates the deep relationships that are critical to our world as well as the astonishing beauty of the structures and connections that surround us. It's impossible to read this book and look at either Earth or sky again in the same way.

    More than 3 billion miles from Earth, a small NASA spacecraft called New Horizons screamed past Pluto at more than 32,000 miles per hour, focusing its instruments on the long mysterious icy worlds of the Pluto system, and then, just as quickly, continued on its journey out into the beyond.Nothing like this has occurred in a generation--a raw exploration of new worlds unparalleled since NASA's Voyager missions to Uranus and Neptune--and nothing like it is planned to happen ever again. The photos that New Horizons sent back to Earth graced the front pages of newspapers on all 7 continents, and NASA's website for the mission received more than 2 billion hits in the days surrounding the flyby. At a time when so many think our most historic achievements are in the past, the most distant planetary exploration ever attempted not only succeeded but made history and captured the world's imagination.How did this happen? Chasing New Horizons is the story of the men and women behind the mission: of their decades-long commitment; of the political fights within and outside of NASA; of the sheer human ingenuity it took to design, build, and fly the mission; and of the plans for New Horizons' next encounter, 1 billion miles past Pluto. Told from the insider's perspective of Dr. Alan Stern--the man who led the mission--Chasing New Horizons is a riveting story of scientific discovery, and of how far humanity can go when people focused on a dream work together toward their incredible goal.