This was the world of medicine when Thomas Dent Mütter began his trailblazing career as a plastic surgeon in Philadelphia during the middle of the nineteenth century.Although he died at just forty-eight, Mütter was an audacious medical innovator who pioneered the use of ether as anesthesia, the sterilization of surgical tools, and a compassion-based vision for helping the severely deformed, which clashed spectacularly with the sentiments of his time.   Brilliant, outspoken, and brazenly handsome, Mütter was flamboyant in every aspect of his life. He wore pink silk suits to perform surgery, added an umlaut to his last name just because he could, and amassed an immense collection of medical oddities that would later form the basis of Philadelphia’s Mütter Museum. Cristin O’Keefe Aptowicz chronicles how Mütter’s efforts helped establish Philadelphia as a global mecca for medical innovation—despite intense resistance from his numerous rivals.

    From distressed small communities in Central Appalachia to wealthy suburbs; from disparate cities to once-idyllic farm towns; it's a heartbreaking trajectory that illustrates how this national crisis has persisted for so long and become so firmly entrenched. Beginning with a single dealer who lands in a small Virginia town and sets about turning high school football stars into heroin overdose statistics, Macy endeavors to answer a grieving mother's question-why her only son died-and comes away with a harrowing story of greed and need. From the introduction of OxyContin in 1996, Macy parses how America embraced a medical culture where overtreatment with painkillers became the norm. In some of the same distressed communities featured in her bestselling book Factory Man, the unemployed use painkillers both to numb the pain of joblessness and pay their bills, while privileged teens trade pills in cul-de-sacs, and even high school standouts fall prey to prostitution, jail, and death.Through unsparing, yet deeply human portraits of the families and first responders struggling to ameliorate this epidemic, each facet of the crisis comes into focus. In these politically fragmented times, Beth Macy shows, astonishingly, that the only thing that unites Americans across geographic and class lines is opioid drug abuse. But in a country unable to provide basic healthcare for all, Macy still finds reason to hope-and signs of the spirit and tenacity necessary in those facing addiction to build a better future for themselves and their families.

     Drawing from a lifetime of lessons learned, seven-time Emmy winner Betty White's wit and wisdom take center stage as she tackles topics like friendship, romantic love, aging, television, fans, love for animals, and the brave new world of celebrity. If You Ask Me mixes her thoughtful observations with humorous stories from a seven- decade career in Hollywood. Longtime fans and new fans alike will relish Betty's candid take on everything from her rumored crush on Robert Redford (true) to her beauty regimen ("I have no idea what color my hair is and I never intend to find out") to the Facebook campaign that helped persuade her to host Saturday Night Live despite her having declined the hosting job three times already. Featuring all-new material, with a focus on the past fifteen years of her life, If You Ask Me is funny, sweet, and to the point-just like Betty White.

    Now, Amy Schumer has written a refreshingly candid and uproariously funny collection of (extremely) personal and observational essays. In The Girl with the Lower Back Tattoo, Amy mines her past for stories about her teenage years, her family, relationships, and sex and shares the experiences that have shaped who she is - a woman with the courage to bare her soul to stand up for what she believes in, all while making us laugh.Ranging from the raucous to the romantic, the heartfelt to the harrowing, this highly entertaining and universally appealing collection is the literary equivalent of a night out with your best friends - an unforgettable and fun adventure that you wish could last forever. Whether she's experiencing lust-at-first-sight while in the airport security line, sharing her own views on love and marriage, admitting to being an introvert, or discovering her cross-fit instructor's secret bad habit, Amy Schumer proves to be a bighearted, brave, and thoughtful storyteller that will leave you nodding your head in recognition, laughing out loud, and sobbing uncontrollably - but only because it's over.

    And that's what Furiously Happy is all about."Jenny’s readings are standing room only, with fans lining up to have Jenny sign their bottles of Xanax or Prozac as often as they are to have her sign their books. Furiously Happy appeals to Jenny's core fan base but also transcends it. There are so many people out there struggling with depression and mental illness, either themselves or someone in their family—and in Furiously Happy they will find a member of their tribe offering up an uplifting message (via a taxidermied roadkill raccoon). Let's Pretend This Never Happened ostensibly was about embracing your own weirdness, but deep down it was about family. Furiously Happy is about depression and mental illness, but deep down it's about joy—and who doesn't want a bit more of that?

    Forced to remain inside until they'd "proven" themselves sane, all eight emerged with alarming diagnoses and even more troubling stories of their treatment. Rosenhan's study broke open the field of psychiatry, closing down institutions and changing mental health diagnosis forever. But, as Cahalan's new research shows, very little in this saga is exactly as it seems. What really happened behind those closed asylum doors, and what does it mean for our understanding of mental illness today?

    In her book Self-Inflicted Wounds, comedian, actress, and cohost of CBS’s daytime hit show The Talk, Aisha Tyler recounts a series of epic mistakes and hilarious stories of crushing personal humiliation, and the personal insights and authentic wisdom she gathered along the way. The essays in Self-Inflicted Wounds are refreshingly and sometimes brutally honest, surprising, and laugh-out-loud funny, vividly translating the brand of humor Tyler has cultivated through her successful standup career, as well as the strong voice and unique point of view she expresses on her taste-making comedy podcast Girl on Guy. Riotous, revealing, and wonderfully relatable, Aisha Tyler’s Self-Inflicted Wounds: Heartwarming Tales of Epic Humiliation is about the power of calamity to shape life, learning, and success.

    His assailant ran down the street, jumped into an SUV, and vanished, hoping to join the vast majority of killers in American cities who are never arrested for their crimes. But as soon as the case was assigned to Detective John Skaggs, the odds shifted. Here is the kaleidoscopic story of the quintessential American murder--one young black man slaying another--and a determined crew of detectives whose creed was to pursue justice at all costs for its forgotten victims. Ghettoside is a fast-paced narrative of a devastating crime, an intimate portrait of detectives and a community bonded in tragedy, and a surprising new lens into the great subject of murder in America--why it happens and how the plague of killings might yet be stopped.

    But when she least expects it, her reckless past catches up with her; convicted and sentenced to fifteen months at an infamous women's prison in Connecticut, Piper becomes inmate #11187-424. From her first strip search to her final release, she learns to navigate this strange world with its arbitrary rules and codes, its unpredictable, even dangerous relationships. She meets women from all walks of life, who surprise her with tokens of generosity, hard truths and simple acts of acceptance.

    Or, rather, to welcome him back. It had been thirty years since the Revolutionary War hero the Marquis de Lafayette had last set foot in the United States, and he was so beloved that 80,000 people showed up to cheer for him. The entire population of New York at the time was 120,000. Lafayette's arrival in 1824 coincided with one of the most contentious presidential elections in American history, Congress had just fought its first epic battle over slavery, and the threat of a Civil War loomed. But Lafayette, belonging to neither North nor South, to no political party or faction, was a walking, talking reminder of the sacrifices and bravery of the revolutionary generation and what they wanted this country to be. His return was not just a reunion with his beloved Americans, it was a reunion for Americans with their own astonishing singular past. Lafayette in the Somewhat United States is a humorous and insightful portrait of the famed Frenchman, the impact he had on our young country, and his ongoing relationship with some of the instrumental Americans of the time, including George Washington, Alexander Hamilton, Thomas Jefferson, and many more.

    Third-degree burns covered 35% of her body, and the prognosis wasn't good. But she survived. Burned and scarred, the impact stayed with her and became an obstacle she was determined to overcome. Feeling like a misfit led to her love of horror. While her sisters played with Barbie dolls, Cassandra built model kits of Frankenstein and Dracula, and idolized Vincent Price.Due to a complicated relationship with her mother, Cassandra left home at 14, and by age 17 she was performing at the famed Dunes Hotel in Las Vegas. Run-ins with the likes of Frank Sinatra, Sammy Davis Jr., and Tom Jones helped her grow up fast. Then a chance encounter with her idol Elvis Presley, changed the course of her life forever, and led her to Europe where she worked in film and traveled Italy as lead singer of an Italian pop band. She eventually made her way to Los Angeles, where she joined the famed comedy improv group, The Groundlings, and worked alongside Phil Hartman and Paul "Pee-wee" Reubens, honing her comedic skills.Nearing age 30, a struggling actress considered past her prime, she auditioned at local LA channel KHJ as hostess for the late night vintage horror movies. Cassandra improvised, made the role her own, and got the job on the spot. Yours Cruelly, Elvira is an unforgettably wild memoir. Cassandra doesn't shy away from revealing exactly who she is and how she overcame seemingly insurmountable odds. Always original and sometimes outrageous, her story is loaded with twists, travails, revelry, and downright shocking experiences. It is the candid, often funny, and sometimes heart-breaking tale of a Midwest farm girl's long strange trip to become the world's sexiest, sassiest Halloween icon.

    Yes, you totally recognize her. And, odds are, you already feel like she’s your friend. In her first book of essays, I Don’t Know What You Know Me From, Greer writes about everything you would hope to hear from your best friend: how a midnight shopping trip to Walgreens can cure all; what it’s like to wake up one day with stepchildren; and how she really feels about fans telling her that she’s prettier in person. Yes, it’s all here—from the hilarious moments to the intimate confessions.But Judy Greer isn’t just a regular friend—she’s a celebrity friend. Want to know which celebs she’s peed next to? Or what the Academy Awards are actually like? Or which hot actor gave her father a Harley-Davidson? Don’t worry; Greer reveals all of that, too. You’ll love her because, besides being laugh-out-loud funny, she makes us genuinely feel like she’s one of us. Because even though she sometimes has a stylist and a makeup artist, she still wears (and hates!) Spanx. Because even after almost twenty years in Hollywood, she still hasn’t figured everything out—except that you should always wash your face before bed. Always.

    Linda Tirado, in her signature brutally honest yet personable voice, takes all of these preconceived notions and smashes them to bits. She articulates not only what it is to be working poor in America (yes, you can be poor and live in a house and have a job, even two), but what poverty is truly like—on all levels. Frankly and boldly, Tirado discusses openly how she went from lower-middle class, to sometimes middle class, to poor and everything in between, and in doing so reveals why “poor people don’t always behave the way middle-class America thinks they should.”

    From the Space Shuttle training toilet to a crash test of NASA’s new space capsule, Mary Roach takes us on the surreally entertaining trip into the science of life in space and space on Earth.

    Louis to his own television show From a young age, Andy Cohen knew one thing: He loved television. Not in the way that most kids do, but in an irrepressible, all-consuming, I-want-to-climb-inside-the-tube kind of way. And climb inside he did. Now presiding over Bravo's reality TV empire, he started out as an overly talkative pop culture obsessive, devoted to "Charlie's Angels" and "All My Children "and to his mother, who received daily letters from Andy at summer camp, usually reminding her to tape the soaps. In retrospect, it's hard to believe that everyone didn't know that Andy was gay; still, he remained in the closet until college. Finally out, he embarked on making a career out of his passion for television.The journey begins with Andy interviewing his all-time idol Susan Lucci for his college newspaper and ends with him in a job where he has a hand in creating today's celebrity icons. In the witty, no-holds-barred style of his show "Watch What Happens Live," Andy tells tales of absurd mishaps during his ten years at CBS News, hilarious encounters with the heroes and heroines of his youth, and the real stories behind "The Real Housewives." Dishy, funny, and full of heart, "Most Talkative" provides a one-of-a-kind glimpse into the world of television, from a fan who grew up watching the screen and is now inside it, both making shows and hosting his own.