It intersects with Darwin’s theory of evolution, and collides with the horrors of Nazi eugenics in the 1940s. The gene transforms post-war biology. It reorganizes our understanding of sexuality, temperament, choice and free will. This is a story driven by human ingenuity and obsessive minds – from Charles Darwin and Gregor Mendel to Francis Crick, James Watson and Rosalind Franklin, and the thousands of scientists still working to understand the code of codes.This is an epic, moving history of a scientific idea coming to life, by the author of The Emperor of All Maladies. But woven through The Gene, like a red line, is also an intimate history – the story of Mukherjee’s own family and its recurring pattern of mental illness, reminding us that genetics is vitally relevant to everyday lives. These concerns reverberate even more urgently today as we learn to “read” and “write” the human genome – unleashing the potential to change the fates and identities of our children.Majestic in its ambition, and unflinching in its honesty, The Gene gives us a definitive account of the fundamental unit of heredity – and a vision of both humanity’s past and future.

    In the 70s and 80s, it was punk rock and modern art. But for the 1990s, it was all about the fashion—and Kate Moss, Marc Jacobs, and Alexander McQueen were the trio of rebel geniuses who made it great.Veteran style and pop culture journalist Maureen Callahan takes you back to the 90s, to the moment when supermodel glamazons gave way to heroin chic, the alternative became the mainstream, and fashion became the cradle for the most exciting artistic and cultural innovations of the age. Packed with dishy stories of some of the most celebrated personalities of the day, Champagne Supernovas gives you the inside scoop from designers like Anna Sui and Isaac Mizrahi; scenesters like Kim Gordon of Sonic Youth and Sassy magazine's Jane Pratt; plus a bevy of supermodels, stylists, editors, photographers, confidantes, club kids, and scenesters. They'll discuss why Kate Moss and Johnny Depp broke up, how Marc Jacobs came through the crucible of the AIDS crisis, and what really drove Alexander McQueen to suicide.Steeped in the creative brew of art, decadence, and genius that defined the era, Champagne Supernovas gives you front-row tickets to a gloriously debauched soap opera about the losers and freaks who became It Girls and Boys, and changed the world in spite of themselves.

    His assignment is to program the complex lunar landing phase in the Lunar Module's onboard computer. As he masters his art the reader learns about the computer, the mission, and a bit about spacecraft navigation and meets a cast of interesting characters along the way. As Apollo 11 approaches, the author flies lunar landings in simulators and meets the astronauts who will fly the LM for real. He explains the computer alarms that almost prevented Neil Armstrong from landing and describes a narrow escape from another dangerous problem. He helps Pete Conrad achieve a pinpoint landing on Apollo 12, and works with Apollo 16 commander John Young on a technique for landing even more precisely. On Apollo 14 he devises a workaround when a faulty pushbutton threatens Alan Shepard's mission, earning a NASA award, a story in Rolling Stone, and a few lines in the history books. Along the way the author hits the high points of his eclectic personal life, as he enters adulthood in the 1960s. He writes for students of the Apollo project, for whom the development of the flight software is still largely unexplored territory, but also for the young coders of the current digital culture, who will get the author's observations on the art of programming and who may identify as he explores sex, drugs, and the other excitements of the era. The underlying thesis is that the American space program in the 1960s was successful not in spite of, but in large measure because of the idealism, the freedom of thought, and the sense of exploration, inner and outer, that prevailed in the culture during that period. The memoir concludes in a party atmosphere at the spectacular night launch of Apollo 17 before a glittery crowd an occasion that marked the high water mark, so far, of human space exploration.

    You'll never find a wiser advisor with a bigger heart.” -- Malachi Rempen: Filmmaker, cartoonist, author and self-described ruffian This book grew out of a series of letters to my daughter concerning various things—mostly about money and investing—she was not yet quite ready to hear. Since money is the single most powerful tool we have for navigating this complex world we’ve created, understanding it is critical. “But Dad,” she once said, “I know money is important. I just don’t want to spend my life thinking about it.” This was eye-opening. I love this stuff. But most people have better things to do with their precious time. Bridges to build, diseases to cure, treaties to negotiate, mountains to climb, technologies to create, children to teach, businesses to run. Unfortunately, benign neglect of things financial leaves you open to the charlatans of the financial world. The people who make investing endlessly complex, because if it can be made complex it becomes more profitable for them, more expensive for us, and we are forced into their waiting arms. Here’s an important truth: Complex investments exist only to profit those who create and sell them. Not only are they more costly to the investor, they are less effective. The simple approach I created for her and present now to you, is not only easy to understand and implement, it is more powerful than any other. Together we’ll explore: Debt: Why you must avoid it and what to do if you have it. The importance of having F-you Money. How to think about money, and the unique way understanding this is key to building your wealth. Where traditional investing advice goes wrong and what actually works. What the stock market really is and how it really works. Why the stock market always goes up and why most people still lose money investing in it. How to invest in a raging bull, or bear, market. Specific investments to implement these strategies. The Wealth Building and Wealth Preservation phases of your investing life and why they are not always tied to your age. How your asset allocation is tied to those phases and how to choose it. How to simplify the sometimes confusing world of 401(k), 403(b), TSP, IRA and Roth accounts. TRFs (Target Retirement Funds), HSAs (Health Savings Accounts) and RMDs (Required Minimum Distributions). What investment firm to use and why the one I recommend is so far superior to the competition. Why you should be very cautious when engaging an investment advisor and whether you need to at all. Why and how you can be conned, and how to avoid becoming prey. Why I don’t recommend dollar cost averaging. What financial independence looks like and how to have your money support you. What the 4% rule is and how to use it to safely spend your wealth. The truth behind Social Security.

    Early Retirement Extreme shows how I did it and how anyone can formulate their own plan for financial independence. The book provides the principles and framework for a systems theoretical strategy for attaining that independence in 5-10 years. It teaches how a shift in focus from consuming to producing can help people out of the consumer trap, and offers a path to achieving the freedom necessary to pursue interests other than working for a living. The principles in Early Retirement Extreme show how to break the financial chains that hold people back from doing what they truly want to do. The framework has been used by many people over the last few years to accomplish a variety of goals. It provides people a means to achieve almost any goal, whether it's debt-free living, extended travel, a sabbatical, a career change, time off to raise a child, a traditional retirement, or simply a desire for a more resilient and self-sufficient lifestyle. The book was initially written for people in their 20s and 30s, but its ideas aren't limited to early retirees. Middle-aged people in the grips of consumerism can use the principles to take back control of their lives. People closer to retirement age who don't feel adequately prepared can use it to set themselves up for a comfortable retirement in a relatively short period of time. Anyone worried about their financial future can use the principles in Early Retirement Extreme to make their future more secure.

    In a "witty, erudite, and entertaining" (Esquire) style, Simon Garfield explains how the experimental mishap that produced an odd shade of purple revolutionized fashion, as well as industrial applications of chemistry research. Occasionally honored in certain colleges and chemistry clubs, Perkin until now has been a forgotten man.

    From body lotion to tonic water, the popular new element shines bright in the otherwise dark years of the First World War.Meanwhile, hundreds of girls toil amidst the glowing dust of the radium-dial factories. The glittering chemical covers their bodies from head to toe; they light up the night like industrious fireflies. With such a coveted job, these "shining girls" are the luckiest alive—until they begin to fall mysteriously ill.But the factories that once offered golden opportunities are now ignoring all claims of the gruesome side effects, and the women's cries of corruption. And as the fatal poison of the radium takes hold, the brave shining girls find themselves embroiled in one of the biggest scandals of America's early 20th century, and in a groundbreaking battle for workers' rights that will echo for centuries to come.Written with a sparkling voice and breakneck pace, The Radium Girls fully illuminates the inspiring young women exposed to the "wonder" substance of radium, and their awe-inspiring strength in the face of almost impossible circumstances. Their courage and tenacity led to life-changing regulations, research into nuclear bombing, and ultimately saved hundreds of thousands of lives.

    Gates says, "we can work on a local, national, and global level to build the technologies, businesses, and industries to avoid the worst impacts of climate change." His interest in climate change is a natural outgrowth of the efforts by his foundation to reduce poverty and disease. Climate change, according to Gates, will have the biggest impact on the people who have done the least to cause it. As a technologist, he has seen first-hand how innovation can change the world. By investing in research, inventing new technologies, and by deploying them quickly at large scale, Gates believes climate change can be addressed in meaningful ways. According to Gates, "to prevent the worst effects of climate change, we have to get to net-zero emissions of greenhouse gases. This problem is urgent, and the debate is complex, but I believe we can come together to invent new carbon-zero technologies, deploy the ones we have, and ultimately avoid a climate catastrophe."

    Frizzle were a physics student of Stephen Hawking, she might have written THE UNIVERSE IN YOUR HAND, a wild tour through the reaches of time and space, from the interior of a proton to the Big Bang to the rough suburbs of a black hole. It's friendly, excitable, erudite, and cosmic."—Jordan Ellenberg, New York Times besteselling author of How Not To Be WrongQuantum physics, black holes, string theory, the Big Bang, dark matter, dark energy, parallel universes: even if we are interested in these fundamental concepts of our world, their language is the language of math. Which means that despite our best intentions of finally grasping, say, Einstein's Theory of General Relativity, most of us are quickly brought up short by a snarl of nasty equations or an incomprehensible graph.Christophe Galfard's mission in life is to spread modern scientific ideas to the general public in entertaining ways. Using his considerable skills as a brilliant theoretical physicist and successful young adult author, The Universe in Your Hand employs the immediacy of simple, direct language to show us, not explain to us, the theories that underpin everything we know about our universe. To understand what happens to a dying star, we are asked to picture ourselves floating in space in front of it. To get acquainted with the quantum world, we are shrunk to the size of an atom and then taken on a journey. Employing everyday similes and metaphors, addressing the reader directly, and writing stories rather than equations renders these astoundingly complex ideas in an immediate and visceral way.Utterly captivating and entirely unique, The Universe in Your Hand will find its place among other classics in the field.

    Traveling through the dizzying expanse of geologic time—from prehistoric art in Norwegian sea caves, to the blue depths of the Greenland ice cap, to a deep-sunk "hiding place" where nuclear waste will be stored for 100,000 years to come—Underland takes us on an extraordinary journey into our relationship with darkness, burial, and what lies beneath the surface of both place and mind.Global in its geography and written with great lyricism, Underland speaks powerfully to our present moment. At once ancient and urgent, this is a book that will change the way you see the world.

    In this fascinating study, Rozsika Parker traces a hidden history--the shifting notions of femininity and female social roles--by unraveling the history of embroidery from medieval times until today.

    The Only Guide You'll Ever Need for the Right Financial Plan focuses on the art of investing and gives you the information you need to create a strategy that is tailor-made for your particular situation.Designed for savvy investors and professional advisors, this book offers the vital information needed for developing and implementing an overall strategic financial plan. In this essential resource, Swedroe outlines the basics in asset allocation and other investment planning concepts.Addresses how you can design an investment policy statement and an individual asset allocation plan Examines how to maintain your portfolio's risk profile in the most cost-effective and tax-efficient manner Offers insights on integrating risk management and estate planning issues into your plan The Only Guide You'll Ever Need for the Right Financial Plan offers a handy tool to help you make more informed and prudent decisions that will go a long way to ensure a secure financial future.

    But as a new century approached, appetites broadened, and David Fairchild, a young botanist with an insatiable lust to explore and experience the world, set out in search of foods that would enrich the American farmer and enchant the American eater.Kale from Croatia, mangoes from India, and hops from Bavaria. Peaches from China, avocados from Chile, and pomegranates from Malta. Fairchild's finds weren't just limited to food: From Egypt he sent back a variety of cotton that revolutionized an industry, and via Japan he introduced the cherry blossom tree, forever brightening America's capital. Along the way, he was arrested, caught diseases, and bargained with island tribes. But his culinary ambition came during a formative era, and through him, America transformed into the most diverse food system ever created.

    For advanced crafters, this book instructs on features such as modes and functions, and teaches how to create with color, texture, and dimension. A cutting guide teaches the perfect settings to cut every type of material. A separate chapter introduces the new features of Cricut Expression™ 2 and explains how it differs from the original Expression machine. More than 50 creative projects inspire ideas for home décor, gifts, parties, cards, and scrapbook layouts.

    In Tudor, England, when Mary, Queen of Scots, was under house arrest, her needlework carried her messages to the outside world. From the political propaganda of the Bayeux Tapestry, World War I soldiers coping with PTSD, and the maps sewn by schoolgirls in the New World, to the AIDS quilt, Hmong story clothes, and pink pussyhats, women and men have used the language of sewing to make their voices heard, even in the most desperate of circumstances. Threads of Life is a chronicle of identity, protest, memory, power, and politics told through the stories of needlework. Clare Hunter, master of the craft, threads her own narrative as she takes us over centuries and across continents—from medieval France to contemporary Mexico and the United States, and from a POW camp in Singapore to a family attic in Scotland—to celebrate the age-old, universal, and underexplored beauty and power of sewing. Threads of Life is an evocative and moving book about the need we have to tell our story.