Connectome: How the Brain's Wiring Makes Us Who We Are


Sebastian Seung - 2012
    Is it in our genes? The structure of our brains? Our genome may determine our eye color and even aspects of our personality. But our friendships, failures, and passions also shape who we are. The question is: how?Sebastian Seung, a dynamic professor at MIT, is on a quest to discover the biological basis of identity. He believes it lies in the pattern of connections between the brain’s neurons, which change slowly over time as we learn and grow. The connectome, as it’s called, is where our genetic inheritance intersects with our life experience. It’s where nature meets nurture.Seung introduces us to the dedicated researchers who are mapping the brain’s connections, neuron by neuron, synapse by synapse. It is a monumental undertaking—the scientific equivalent of climbing Mount Everest—but if they succeed, it could reveal the basis of personality, intelligence, memory, and perhaps even mental disorders. Many scientists speculate that people with anorexia, autism, and schizophrenia are "wired differently," but nobody knows for sure. The brain’s wiring has never been clearly seen.In sparklingly clear prose, Seung reveals the amazing technological advances that will soon help us map connectomes. He also examines the evidence that these maps will someday allow humans to "upload" their minds into computers, achieving a kind of immortality.Connectome is a mind-bending adventure story, told with great passion and authority. It presents a daring scientific and technological vision for at last understanding what makes us who we are. Welcome to the future of neuroscience.

Complications: A Surgeon's Notes on an Imperfect Science


Atul Gawande - 2002
    Complications lays bare a science not in its idealized form but as it actually is--uncertain, perplexing, and profoundly human.Complications is a 2002 National Book Award Finalist for Nonfiction.

When the Air Hits Your Brain: Tales of Neurosurgery


Frank T. Vertosick Jr. - 1996
    In other words, by all of us."--Dr. Bernie Siegel, author of Love, Medicine and MiraclesRule One for the neurologist in residence: "You ain't never the same when the air hits your brain." In this fascinating book, Dr. Frank Vertosick brings that fact to life through intimate portraits of patients and unsparing yet gripping descriptions of brain surgery.With insight, humor, and poignancy, Dr. Vertosick chronicles his remarkable evolution from naive young intern to world-class neurosurgeon, where he faced, among other challenges, a six week-old infant with a tumor in her brain, a young man struck down in his prime by paraplegia, and a minister with a .22 caliber bullet lodged in his skull. In candid detail, WHEN THE AIR HITS YOUR BRAIN illuminates both the mysteries of the mind and the realities of the operating room."Riveting."--Publishers Weekly

Do No Harm: Stories of Life, Death and Brain Surgery


Henry Marsh - 2014
    Operations on the brain carry grave risks. Every day, leading neurosurgeon Henry Marsh must make agonizing decisions, often in the face of great urgency and uncertainty.If you believe that brain surgery is a precise and exquisite craft, practiced by calm and detached doctors, this gripping, brutally honest account will make you think again. With astonishing compassion and candor, Marsh reveals the fierce joy of operating, the profoundly moving triumphs, the harrowing disasters, the haunting regrets, and the moments of black humor that characterize a brain surgeon's life.Do No Harm provides unforgettable insight into the countless human dramas that take place in a busy modern hospital. Above all, it is a lesson in the need for hope when faced with life's most difficult decisions.

The Upward Spiral: Using Neuroscience to Reverse the Course of Depression, One Small Change at a Time


Alex Korb - 2015
    Based in the latest research in neuroscience, this audiobook offers dozens of little things you can do every day to rewire your brain and create an upward spiral towards a happier, healthier life.Depression doesn't happen all at once. It starts gradually and builds momentum over time. If you go through a difficult experience, you may stop taking care of yourself. You may stop exercising and eating healthy, which will end up making you feel even worse as time goes on. You are caught in a downward spiral, but you may feel too tired, too overwhelmed, and too scared to try and pull yourself back up. The good news is that just one small step can be a step in the right direction.In The Upward Spiral, neuroscientist Alex Korb demystifies the neurological processes in the brain that cause depression and offers effective ways to get better "one little step at a time". In the book, you'll discover that there isn't "one big solution" that will solve your depression. Instead, there are dozens of small, practical things you can do to alleviate your symptoms and start healing. Some are as simple as relaxing certain muscles to reduce feelings of anxiety, while others involve making small efforts toward more positive social interactions. Small steps in the right direction can have profound effects giving you the power to literally "reshape" your brain.Like most people, you probably didn't wake up one day and find yourself completely depressed. Instead, it probably happened over time, as a series of reactions to difficult situations and negative thinking. But if you are ready to reverse the trajectory of your depression and find lasting happiness, this book will show you how.

The Idea of the Brain: The Past and Future of Neuroscience


Matthew Cobb - 2020
    Yet, despite the astonishing discoveries of science, we still have only the vaguest idea of how the brain works. In The Idea of the Brain, scientist and historian Matthew Cobb traces how our conception of the brain has evolved over the centuries. Although it might seem to be a story of ever-increasing knowledge of biology, Cobb shows how our ideas about the brain have been shaped by each era's most significant technologies. Today we might think the brain is like a supercomputer. In the past, it has been compared to a telegraph, a telephone exchange, or some kind of hydraulic system. What will we think the brain is like tomorrow, when new technology arises? The result is an essential read for anyone interested in the complex processes that drive science and the forces that have shaped our marvelous brains.

Sleights of Mind: What the Neuroscience of Magic Reveals about Our Everyday Deceptions


Stephen L. Macknik - 2010
    This book is the result of the authors' yearlong, world-wide exploration of magic and how its principles apply to our behavior. Magic tricks fool us because humans have hardwired processes of attention and awareness that are hackable—a good magician uses your mind's own intrinsic properties against you in a form of mental jujitsu. Now magic can reveal how our brains work in everyday situations. For instance, if you've ever bought an expensive item you'd sworn you'd never buy, the salesperson was probably a master at creating the "illusion of choice," a core technique of magic. The implications of neuromagic go beyond illuminating our behavior; early research points to new approaches for everything from the diagnosis of autism to marketing techniques and education. Sleights of Mind makes neuroscience fun and accessible by unveiling the key connections between magic and the mind.

The Mind of a Mnemonist


Alexander R. Luria - 1965
    From his intimate knowledge of S., the mnemonist, gained from conversations and testing over a period of almost thirty years, A. R. Luria is able to reveal in rich detail not only the obvious strengths of S.’s astonishing memory but also his surprising weaknesses: his crippling inability to forget, his pattern of reacting passively to life, and his uniquely handicapped personality.

Train Your Mind, Change Your Brain: How a New Science Reveals Our Extraordinary Potential to Transform Ourselves


Sharon Begley - 2007
    In late 2004, leading Western scientists joined the Dalai Lama at his home in Dharamsala, India, to address this very question–and in the process brought about a revolution in our understanding of the human mind. In this fascinating and far-reaching book, Wall Street Journal science writer Sharon Begley reports on how cutting-edge science and the ancient wisdom of Buddhism have come together to show how we all have the power to literally change our brains by changing our minds. These findings hold exciting implications for personal transformation.For decades, the conventional wisdom of neuroscience held that the hardware of the brain is fixed and immutable–that we are stuck with what we were born with. As Begley shows, however, recent pioneering experiments in neuroplasticity, a new science that investigates whether and how the brain can undergo wholesale change, reveal that the brain is capable not only of altering its structure but also of generating new neurons, even into old age. The brain can adapt, heal, renew itself after trauma, and compensate for disability. Begley documents how this fundamental paradigm shift is transforming both our understanding of the human mind and our approach to deep-seated emotional, cognitive, and behavioral problems. These breakthroughs show that it is possible to reset our happiness meter, regain the use of limbs disabled by stroke, train the mind to break cycles of depression and OCD, and reverse age-related changes in the brain. They also suggest that it is possible to teach and learn compassion, a key step in the Dalai Lama’s quest for a more peaceful world. But as we learn from studies performed on Buddhist monks, an important component in changing the brain is to tap the power of mind and, in particular, focused attention. This is the classic Buddhist practice of mindfulness, a technique that has become popular in the West and that is immediately available to everyone. With her extraordinary gift for making science accessible, meaningful, and compelling, Sharon Begley illuminates a profound shift in our understanding of how the brain and the mind interact. This tremendously hopeful book takes us to the leading edge of a revolution in what it means to be human.

Shrinks: The Untold Story of Psychiatry


Jeffrey A. Lieberman - 2015
    Lieberman traces the field from its birth as a mystic pseudo-science through its adolescence as a cult of "shrinks" to its late blooming maturity — beginning after World War II — as a science-driven profession that saves lives. With fascinating case studies and portraits of the luminaries of the field — from Sigmund Freud to Eric Kandel — Shrinks is a gripping and illuminating read, and an urgent call-to-arms to dispel the stigma of mental illnesses by treating them as diseases rather than unfortunate states of mind.“A lucid popular history...At once skeptical and triumphalist. It shows just how far psychiatry has come.” —Julia M. Klein, Boston Globe

Idiot Brain: What Your Head Is Really Up To


Dean Burnett - 2016
    But it’s also messy, fallible, and about 50,000 years out of date. We cling to superstitions, remember faces but not names, miss things sitting right in front of us, and lie awake at night while our brains endlessly replay our greatest fears. Idiot Brain is for anyone who has ever wondered why their brain appears to be sabotaging their life—and what on earth it is really up to.A Library Journal Science Bestseller and a Finalist for the Goodreads Choice Award in Science Technology.

The Ravenous Brain: How the New Science of Consciousness Explains Our Insatiable Search for Meaning


Daniel Bor - 2012
    Yet consciousness is subjective, personal, and famously difficult to examine: philosophers have for centuries declared this mental entity so mysterious as to be impenetrable to science.In The Ravenous Brain, neuroscientist Daniel Bor departs sharply from this historical view, and builds on the latest research to propose a new model for how consciousness works. Bor argues that this brain-based faculty evolved as an accelerated knowledge gathering tool. Consciousness is effectively an idea factory -- that choice mental space dedicated to innovation, a key component of which is the discovery of deep structures within the contents of our awareness.This model explains our brains"; ravenous appetite for information -- and in particular, its constant search for patterns. Why, for instance, after all our physical needs have been met, do we recreationally solve crossword or Sudoku puzzles? Such behavior may appear biologically wasteful, but, according to Bor, this search for structure can yield immense evolutionary benefits -- it led our ancestors to discover fire and farming, pushed modern society to forge ahead in science and technology, and guides each one of us to understand and control the world around us. But the sheer innovative power of human consciousness carries with it the heavy cost of mental fragility.Bor discusses the medical implications of his theory of consciousness, and what it means for the origins and treatment of psychiatric ailments, including attention-deficit disorder, schizophrenia, manic depression, and autism. All mental illnesses, he argues, can be reformulated as disorders of consciousness -- a perspective that opens up new avenues of treatment for alleviating mental suffering.A controversial view of consciousness, The Ravenous Brain links cognition to creativity in an ingenious solution to one of science's biggest mysteries.

The Seven Sins of Memory: How the Mind Forgets and Remembers


Daniel L. Schacter - 2001
    Schacter explores instances of what we would consider memory failure—absent-mindedness, transience, blocking, misattribution, suggestibility, bias, and persistence—and suggests instead that these miscues are actually indications that memory is functioning as designed. Drawing from vivid scientific research and creative literature, as well as high-profile events in which memory has figured significantly (Bill Clinton's grand jury testimony, for instance), The Seven Sins of Memory provides a more nuanced understanding of how memory and the mind influence each other and shape our lives.

Into the Silent Land: Travels in Neuropsychology


Paul Broks - 2003
    Broks fuses classic cases of neuropsychology with the his own case studies, philosophical debate, and thought provoking riffs and meditations on the nature of neurological impairments and dysfunctions.

The Man Who Wasn't There: Investigations into the Strange New Science of the Self


Anil Ananthaswamy - 2015
    These individuals all lost some part of what we think of as our self, but they then offer remarkable, sometimes heart-wrenching insights into what remains. One man cut off his own leg. Another became one with the universe.We are learning about the self at a level of detail that Descartes (“I think therefore I am”) could never have imagined. Recent research into Alzheimer’s illuminates how memory creates your narrative self by using the same part of your brain for your past as for your future. But wait, those afflicted with Cotard’s syndrome think they are already dead; in a way, they believe that “I think therefore I am not.” Who—or what—can say that? Neuroscience has identified specific regions of the brain that, when they misfire, can cause the self to move back and forth between the body and a doppelgänger, or to leave the body entirely. So where in the brain, or mind, or body, is the self actually located? As Ananthaswamy elegantly reports, neuroscientists themselves now see that the elusive sense of self is both everywhere and nowhere in the human brain.