Operations on the brain carry grave risks. Every day, leading neurosurgeon Henry Marsh must make agonizing decisions, often in the face of great urgency and uncertainty.If you believe that brain surgery is a precise and exquisite craft, practiced by calm and detached doctors, this gripping, brutally honest account will make you think again. With astonishing compassion and candor, Marsh reveals the fierce joy of operating, the profoundly moving triumphs, the harrowing disasters, the haunting regrets, and the moments of black humor that characterize a brain surgeon's life.Do No Harm provides unforgettable insight into the countless human dramas that take place in a busy modern hospital. Above all, it is a lesson in the need for hope when faced with life's most difficult decisions.

    Randall never gave sleep much thought. That is, until he began sleepwalking. One midnight crash into a hallway wall sent him on an investigation into the strange science of sleep.In Dreamland, Randall explores the research that is investigating those dark hours that make up nearly a third of our lives. Taking readers from military battlefields to children’s bedrooms, Dreamland shows that sleep isn't as simple as it seems. Why did the results of one sleep study change the bookmakers’ odds for certain Monday Night Football games? Do women sleep differently than men? And if you happen to kill someone while you are sleepwalking, does that count as murder?This book is a tour of the often odd, sometimes disturbing, and always fascinating things that go on in the peculiar world of sleep. You’ll never look at your pillow the same way again.

    Applying the same objective criteria to legal and illegal substances, an argument is made that legality is not a clear measure for harm. Tackling a variety of questions, such as Which is more harmful—Ecstasy or alcohol? Can addiction be cured? and Does the "War on Drugs" have serious unintended effects that can hurt children?, this analysis equips readers with the ability to make educated decisions regarding drugs both personally and in their communities. Broadening the scope of the discussion, a framework is explored for formulating national drug policies that will minimize a myriad of harms—social, medical, criminal, financial, and environmental.

    Sapolsky's storytelling concept is delightful but it also has a powerful intrinsic logic: he starts by looking at the factors that bear on a person's reaction in the precise moment a behavior occurs, and then hops back in time from there, in stages, ultimately ending up at the deep history of our species and its evolutionary legacy.And so the first category of explanation is the neurobiological one. A behavior occurs--whether an example of humans at our best, worst, or somewhere in between. What went on in a person's brain a second before the behavior happened? Then Sapolsky pulls out to a slightly larger field of vision, a little earlier in time: What sight, sound, or smell caused the nervous system to produce that behavior? And then, what hormones acted hours to days earlier to change how responsive that individual is to the stimuli that triggered the nervous system? By now he has increased our field of vision so that we are thinking about neurobiology and the sensory world of our environment and endocrinology in trying to explain what happened.Sapolsky keeps going: How was that behavior influenced by structural changes in the nervous system over the preceding months, by that person's adolescence, childhood, fetal life, and then back to his or her genetic makeup? Finally, he expands the view to encompass factors larger than one individual. How did culture shape that individual's group, what ecological factors millennia old formed that culture? And on and on, back to evolutionary factors millions of years old.The result is one of the most dazzling tours d'horizon of the science of human behavior ever attempted, a majestic synthesis that harvests cutting-edge research across a range of disciplines to provide a subtle and nuanced perspective on why we ultimately do the things we do...for good and for ill. Sapolsky builds on this understanding to wrestle with some of our deepest and thorniest questions relating to tribalism and xenophobia, hierarchy and competition, morality and free will, and war and peace. Wise, humane, often very funny, Behave is a towering achievement, powerfully humanizing, and downright heroic in its own right.

    Today, mental disturbance is most commonly viewed through a medical lens, but societies have also sought to make sense of it through religion or the supernatural, or by constructing psychological or social explanations in an effort to tame the demons of unreason. Madness in Civilization traces the long and complex history of this affliction and our attempts to treat it.Beautifully illustrated throughout, Madness in Civilization takes readers from antiquity to today, painting a vivid and often harrowing portrait of the different ways that cultures around the world have interpreted and responded to the seemingly irrational, psychotic, and insane. From the Bible to Sigmund Freud, from exorcism to mesmerism, from Bedlam to Victorian asylums, from the theory of humors to modern pharmacology, the book explores the manifestations and meanings of madness, its challenges and consequences, and our varied responses to it. It also looks at how insanity has haunted the imaginations of artists and writers and describes the profound influence it has had on the arts, from drama, opera, and the novel to drawing, painting, and sculpture.Written by one of the world’s preeminent historians of psychiatry, Madness in Civilization is a panoramic history of the human encounter with unreason.

    But is it possible America's most troubling impact on the globalizing world has yet to be accounted for? In "Crazy Like Us," Ethan Watters reveals that the most devastating consequence of the spread of American culture has not been our golden arches or our bomb craters but our bulldozing of the human psyche itself: We are in the process of homogenizing the way the world goes mad. America has been the world leader in generating new mental health treatments and modern theories of the human psyche. We export our psychopharmaceuticals packaged with the certainty that our biomedical knowledge will relieve the suffering and stigma of mental illness. We categorize disorders, thereby defining mental illness and health, and then parade these seemingly scientific certainties in front of the world. The blowback from these efforts is just now coming to light: It turns out that we have not only been changing the way the world talks about and treats mental illness -- we have been changing the mental illnesses themselves.For millennia, local beliefs in different cultures have shaped the experience of mental illness into endless varieties." Crazy Like Us" documents how American interventions have discounted and worked to change those indigenous beliefs, often at a dizzying rate. Over the last decades, mental illnesses popularized in America have been spreading across the globe with the speed of contagious diseases. Watters travels from China to Tanzania to bring home the unsettling conclusion that the virus is us: As we introduce Americanized ways of treating mental illnesses, we are in fact spreading the diseases.In post-tsunami Sri Lanka, Watters reports on the Western trauma counselors who, in their rush to help, inadvertently trampled local expressions of grief, suffering, and healing. In Hong Kong, he retraces the last steps of the teenager whose death sparked an epidemic of the American version of anorexia nervosa. Watters reveals the truth about a multi-million-dollar campaign by one of the world's biggest drug companies to change the Japanese experience of depression -- literally marketing the disease along with the drug.But this book is not just about the damage we've caused in faraway places. Looking at our impact on the psyches of people in other cultures is a gut check, a way of forcing ourselves to take a fresh look at our own beliefs about mental health and healing. When we examine our assumptions from a farther shore, we begin to understand how our own culture constantly shapes and sometimes creates the mental illnesses of our time. By setting aside our role as the world's therapist, we may come to accept that we have as much to learn from other cultures' beliefs about the mind as we have to teach.

    When first published in 1963 this landmark of investigative journalism became a runaway bestseller and resulted in legislation to protect grieving families from the unscrupulous sales practices of those in "the dismal trade."Just before her death in 1996, Mitford thoroughly revised and updated her classic study. The American Way of Death Revisited confronts new trends, including the success of the profession's lobbyists in Washington, inflated cremation costs, the telemarketing of pay-in-advance graves, and the effects of monopolies in a death-care industry now dominated by multinational corporations. With its hard-nosed consumer activism and a satiric vision out of Evelyn Waugh's novel The Loved One, The American Way of Death Revisited will not fail to inform, delight, and disturb.

    But Burma's connection to George Orwell is not merely metaphorical; it is much deeper and more real. Orwell's mother was born in Burma, at the height of the British raj, and Orwell was fundamentally shaped by his experiences in Burma as a young man working for the British Imperial Police. When Orwell died, the novel-in-progress on his desk was set in Burma. It is the place George Orwell's work holds in Burma today, however, that most struck Emma Larkin. She was frequently told by Burmese acquaintances that Orwell did not write one book about their country - his first novel, Burmese Days - but in fact he wrote three, the "trilogy" that included Animal Farm and Nineteen Eighty-Four. When Larkin quietly asked one Burmese intellectual if he knew the work of George Orwell, he stared blankly for a moment and then said, "Ah, you mean the prophet!"In one of the most intrepid political travelogues in recent memory, Emma Larkin tells of the year she spent traveling through Burma using the life and work of George Orwell as her compass. Going from Mandalay and Rangoon to poor delta backwaters and up to the old hill-station towns in the mountains of Burma's far north, Larkin visits the places where Orwell worked and lived, and the places his books live still. She brings to vivid life a country and a people cut off from the rest of the world, and from one another, by the ruling military junta and its vast network of spies and informers. Using Orwell enables her to show, effortlessly, the weight of the colonial experience on Burma today, the ghosts of which are invisible and everywhere. More important, she finds that the path she charts leads her to the people who have found ways to somehow resist the soul-crushing effects of life in this most cruel police state. And George Orwell's moral clarity, hatred of injustice, and keen powers of observation serve as the author's compass in another sense too: they are qualities she shares and they suffuse her book - the keenest and finest reckoning with life in this police state that has yet been written.

    . . when it comes to the legacy of this country's war on drugs, we should all share his outrage." --The New York Times Book Review From one of the world's foremost experts on the subject, a powerful argument that the greatest damage from drugs flows from their being illegal, and a hopeful reckoning with the possibility of their use as part of a responsible and happy lifeDr. Carl L. Hart, Ziff Professor at Columbia University and former chair of the Department of Psychology, is one of the world's preeminent experts on the effects of so-called recreational drugs on the human mind and body. Dr. Hart is open about the fact that he uses drugs himself, in a happy balance with the rest of his full and productive life as a colleague, husband, father, and friend. In Drug Use for Grown-Ups, he draws on decades of research and his own personal experience to argue definitively that the criminalization and demonization of drug use--not drugs themselves--have been a tremendous scourge on America, not least in reinforcing this country's enduring structural racism.Dr. Hart did not always have this view. He came of age in one of Miami's most troubled neighborhoods at a time when many ills were being laid at the door of crack cocaine. His initial work as a researcher was aimed at proving that drug use caused bad outcomes. But one problem kept cropping up: the evidence from his research did not support his hypothesis. From inside the massively well-funded research arm of the American war on drugs, he saw how the facts did not support the ideology. The truth was dismissed and distorted in order to keep fear and outrage stoked, the funds rolling in, and Black and brown bodies behind bars.Drug Use for Grown-Ups will be controversial, to be sure: the propaganda war, Dr. Hart argues, has been tremendously effective. Imagine if the only subject of any discussion about driving automobiles was fatal car crashes. Drug Use for Grown-Ups offers a radically different vision: when used responsibly, drugs can enrich and enhance our lives. We have a long way to go, but the vital conversation this book will generate is an extraordinarily important step.

    In Nobody’s Normal, anthropologist Roy Richard Grinker chronicles the progress and setbacks in the struggle against mental-illness stigma—from the eighteenth century, through America’s major wars, and into today’s high-tech economy.Grinker infuses the book with the personal history of his family’s four generations of involvement in psychiatry, including his grandfather’s analysis with Sigmund Freud, his own daughter’s experience with autism, and culminating in his research on neurodiversity. Drawing on cutting-edge science, historical archives, and cross-cultural research in Africa and Asia, Nobody’s Normal explains how we are transforming mental illness and offers a path to end the shadow of stigma. The preeminent historian of medicine, Sander Gilman, calls Nobody’s Normal “the most important work on stigma in more than half a century.”

    The Netherlands are a tiny nation that punch above their weight on the world stage, where prostitutes are entitled to sick pay and prisons are closing due to lack of demand. After a chance encounter, Ben Coates left behind life in London to move to the Netherlands, where he learned the language, worked for Dutch company and married a Dutch wife. He takes readers into the heart of his adopted country, going beyond the usual tourist attractions and cliches to explore what it is that makes the Dutch the Dutch, Holland not the Netherlands and the colour orange so important. A travelogue, a history and a personal account of a changing country - Ben Coates tells the tale of an Englishman who went Dutch and liked it.

    A few years ago, Mark Adams made a strange discovery: Everything we know about the lost city of Atlantis comes from the work of one man, the Greek philosopher Plato. Then he made a second, stranger discovery: Amateur explorers are still actively searching for this sunken city all around the world, based entirely on the clues Plato left behind. Exposed to the Atlantis obsession, Adams decides to track down these people and determine why they believe it’s possible to find the world’s most famous lost city and whether any of their theories could prove or disprove its existence. He visits scientists who use cutting-edge technology to find legendary civilizations once thought to be fictional. He examines the numerical and musical codes hidden in Plato’s writings, and with the help of some charismatic sleuths traces their roots back to Pythagoras, the sixth-century BC mathematician. He learns how ancient societies transmitted accounts of cataclysmic events—and how one might dig out the “kernel of truth” in Plato’s original tale.Meet Me in Atlantis is Adams’s enthralling account of his quest to solve one of history’s greatest mysteries; a travelogue that takes readers to fascinating locations to meet irresistible characters; and a deep, often humorous look at the human longing to rediscover a lost world.

    He learned the tricks of master trail-builders, hunted down long-lost Cherokee trails, and traced the origins of our road networks and the Internet. In each chapter, Moor interweaves his adventures with findings from science, history, philosophy, and nature writing—combining the nomadic joys of Peter Matthiessen with the eclectic wisdom of Lewis Hyde’s The Gift.Throughout, Moor reveals how this single topic—the oft-overlooked trail—sheds new light on a wealth of age-old questions: How does order emerge out of chaos? How did animals first crawl forth from the seas and spread across continents? How has humanity’s relationship with nature and technology shaped world around us? And, ultimately, how does each of us pick a path through life?Moor has the essayist’s gift for making new connections, the adventurer’s love for paths untaken, and the philosopher’s knack for asking big questions. With a breathtaking arc that spans from the dawn of animal life to the digital era, On Trails is a book that makes us see our world, our history, our species, and our ways of life anew.

      We swim in freezing Arctic waters and piranha-infested rivers to test our limits. We swim for pleasure, for exercise, for healing. But humans, unlike other animals that are drawn to water, are not natural-born swimmers. We must be taught. Our evolutionary ancestors learned for survival; now, in the twenty-first century, swimming is one of the most popular activities in the world.Why We Swim is propelled by stories of Olympic champions, a Baghdad swim club that meets in Saddam Hussein’s palace pool, modern-day Japanese samurai swimmers, and even an Icelandic fisherman who improbably survives a wintry six-hour swim after a shipwreck. New York Times contributor Bonnie Tsui, a swimmer herself, dives into the deep, from the San Francisco Bay to the South China Sea, investigating what about water—despite its dangers—seduces us and why we come back to it again and again.

    Spurred by the realization that they had nearly completed high school without hearing any substantive discussion about racism in school, the two young women deferred college admission for a year to collect first-person accounts of how racism plays out in this country every day--and often in unexpected ways.In Tell Me Who You Are, Guo and Vulchi reveal the lines that separate us based on race or other perceived differences and how telling our stories--and listening deeply to the stories of others--are the first and most crucial steps we can take towards negating racial inequity in our culture. Featuring interviews with over 150 Americans accompanied by their photographs, this intimate toolkit also offers a deep examination of the seeds of racism and strategies for effecting change.This groundbreaking book will inspire readers to join Guo and Vulchi in imagining an America in which we can fully understand and appreciate who we are.