Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings? A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.

    Part 1 is about the purpose and importance of having principles in general, having nothing to do with mine. Part 2 explains my most fundamental life principles that apply to everything I do. Part 3, explains my management principles as they are being lived out at Bridgewater. Since my management principles are simply my most fundamental life principles applied to management, reading Part 2 will help you to better understand Part 3, but it’s not required—you can go directly to Part 3 to see what my management principles are and how Bridgewater has been run. One day I’d like to write a Part 4 on my investment principles. If you are looking to get the most bang for your buck (i.e., understanding for the effort), I suggest that you read Parts 1 and 2, and the beginning of Part 3 (through the Summary and Table of Principles) which will give you nearly the whole picture. It’s only about 55 pages of a normal size book. Above all else, I want you to think for yourself—to decide 1) what you want, 2) what is true and 3) what to do about it. I want you to do that in a clear-headed thoughtful way, so that you get what you want. I wrote this book to help you do that. I am going to ask only two things of you—1) that you be open-minded and 2) that you honestly answer some questions about what you want, what is true and what you want to do about it. If you do these things, I believe that you will get a lot out of this book. If you can’t do these things, you should reflect on why that is, because you probably have discovered one of your greatest impediments to getting what you want out of life.

    Their days are defined by a relentless barrage of incoming messages and back-and-forth digital conversations--a state of constant, anxious chatter in which nobody can disconnect, and so nobody has the cognitive bandwidth to perform substantive work. There was a time when tools like email felt cutting edge, but a thorough review of current evidence reveals that the hyperactive hive mind workflow they helped create has become a productivity disaster, reducing profitability and perhaps even slowing overall economic growth. Equally worrisome, it makes us miserable. Humans are simply not wired for constant digital communication.We have become so used to an inbox-driven workday that it's hard to imagine alternatives. But they do exist. Drawing on years of investigative reporting, author and computer science professor Cal Newport makes the case that our current approach to work is broken, then lays out a series of principles and concrete instructions for fixing it. In A World without Email, he argues for a workplace in which clear processes--not haphazard messaging--define how tasks are identified, assigned and reviewed. Each person works on fewer things (but does them better), and aggressive investment in support reduces the ever-increasing burden of administrative tasks. Above all else, important communication is streamlined, and inboxes and chat channels are no longer central to how work unfolds.The knowledge sector's evolution beyond the hyperactive hive mind is inevitable. The question is not whether a world without email is coming (it is), but whether you'll be ahead of this trend. If you're a CEO seeking a competitive edge, an entrepreneur convinced your productivity could be higher, or an employee exhausted by your inbox, A World Without Email will convince you that the time has come for bold changes, and will walk you through exactly how to make them happen.

    

    How can we catch schools that cheat on standardized tests? How does Netflix know which movies you’ll like? What is causing the rising incidence of autism? As best-selling author Charles Wheelan shows us in Naked Statistics, the right data and a few well-chosen statistical tools can help us answer these questions and more.For those who slept through Stats 101, this book is a lifesaver. Wheelan strips away the arcane and technical details and focuses on the underlying intuition that drives statistical analysis. He clarifies key concepts such as inference, correlation, and regression analysis, reveals how biased or careless parties can manipulate or misrepresent data, and shows us how brilliant and creative researchers are exploiting the valuable data from natural experiments to tackle thorny questions.And in Wheelan’s trademark style, there’s not a dull page in sight. You’ll encounter clever Schlitz Beer marketers leveraging basic probability, an International Sausage Festival illuminating the tenets of the central limit theorem, and a head-scratching choice from the famous game show Let’s Make a Deal—and you’ll come away with insights each time. With the wit, accessibility, and sheer fun that turned Naked Economics into a bestseller, Wheelan defies the odds yet again by bringing another essential, formerly unglamorous discipline to life.

    But, for the uninitiated, most of this information can be indecipherable. The Basics of Bitcoins and Blockchains aims to provide an accessible guide to this new currency and the revolutionary technology that powers it.Bitcoin, Ethereum, and other cryptocurrencies: Gain an understanding of a broad spectrum of Bitcoin topics. The Basics of Bitcoins and Blockchains covers topics such as the history of Bitcoin, the Bitcoin blockchain, and Bitcoin buying, selling, and mining. It also answers how payments are made and how transactions are kept secure. Other cryptocurrencies and cryptocurrency pricing are examined, answering how one puts a value on cryptocurrencies and digital tokens.Blockchain technology: Blockchain technology underlies all cryptocurrencies and cryptocurrency transactions. But what exactly is a blockchain, how does it work, and why is it important? The Basics of Bitcoins and Blockchains will answer these questions and more. Learn about notable blockchain platforms, smart contracts, and other important facets of blockchains and their function in the changing cyber-economy.Things to know before buying cryptocurrencies: The Basics of Bitcoins and Blockchains offers trustworthy and balanced insights to those interested in Bitcoin investing or investing in other cryptocurrency. Discover the risks and mitigations, learn how to identify scams, and understand cryptocurrency exchanges, digital wallets, and regulations with this book.Readers will learn about: Bitcoin and other cryptocurrencies Blockchain technology and how it works The workings of the cryptocurrency market The evolution and potential impacts of Bitcoin and blockchains on global businesses Dive into the world of cryptocurrency with confidence with this comprehensive introduction.

    A Vintage Original.Hope Jahren is an award-winning geobiologist, a brilliant writer, and one of the seven billion people with whom we share this earth. The Story of More is her impassioned open letter to humanity as we stand at the crossroads of survival and extinction. Jahren celebrates the long history of our enterprising spirit--which has tamed wild crops, cured diseases, and sent us to the moon--but also shows how that spirit has created excesses that are quickly warming our planet to dangerous levels. In short, highly readable chapters, she takes us through the science behind the key inventions--from electric power to large-scale farming and automobiles--that, even as they help us, release untenable amounts of carbon dioxide. She explains the current and projected consequences of greenhouse gases--from superstorms to rising sea levels--and the science-based tools that could help us fight back. At once an explainer on the mechanisms of warming and a capsule history of human development, The Story of More illuminates the link between our consumption habits and our endangered earth, showing us how we can use less and share more. It is the essential pocket primer on climate change that will leave an indelible impact on everyone who reads it.

    From his youth as the son of a French Canadian blacksmith to the thrilling, ambitious climbing expeditions that inspired his innovative designs for the sport's equipment, Let My People Go Surfing is the story of a man who brought doing good and having grand adventures into the heart of his business life-a book that will deeply affect entrepreneurs and outdoor enthusiasts alike.

    Like many others, I feel like I have learned more in the last couple of years studying Bitcoin than I have during two decades of formal education. The following lessons are a distillation of what I’ve learned. First published as an article series titled “What I’ve Learned From Bitcoin,” what follows can be seen as a third edition of the original series. Like Bitcoin, these lessons aren’t a static thing. I plan to work on them periodically, releasing updated versions and additional material in the future.Bitcoin is an inexhaustible teacher, which is why I do not claim that these lessons are all-encompassing or complete. They are a reflection of my personal journey down the rabbit hole. There are many more lessons to be learned, and every person will learn something different from entering the world of Bitcoin. I hope that you will find these lessons useful and that the process of learning them by reading won’t be as arduous and painful as learning them firsthand.

    We will always have exactly as much water on Earth as we have ever had. Water cannot be destroyed, and it can always be made clean enough for drinking again. In fact, water can be made so clean that it actually becomes toxic. As Charles Fishman brings vibrantly to life in this delightful narrative excursion, water runs our world in a host of awe-inspiring ways, which is both the promise and the peril of our unexplored connections to it. Taking listeners from the wet moons of Saturn to the water-obsessed hotels of Las Vegas, and from a rice farm in the Australian outback to a glimpse into giant vats of soup at Campbell's largest factory, he reveals that our relationship to water is conflicted and irrational, neglected and mismanaged. Whether we will face a water scarcity crisis has little to do with water and everything to do with how we think about water-how we use it, connect with it, and understand it.Portraying and explaining both the dangers-in 2008, Atlanta came just ninety days from running completely out of drinking water-and the opportunities, such as advances in rainwater harvesting and businesses that are making huge breakthroughs in water productivity, The Big Thirst will forever change the way we think about water, our crucial relationship to it, and the creativity we can bring to ensuring we always have plenty of it.

    It’s time we stand face-to-digital-face with the true powers and limitations of the algorithms that already automate important decisions in healthcare, transportation, crime, and commerce. Hello World is indispensable preparation for the moral quandaries of a world run by code, and with the unfailingly entertaining Hannah Fry as our guide, we’ll be discussing these issues long after the last page is turned.

    How did we end up in this mess?In this masterful new history, Andreas Malm claims it all began in Britain with the rise of steam power. But why did manufacturers turn from traditional sources of power, notably water mills, to an engine fired by coal? Contrary to established views, steam offered neither cheaper nor more abundant energy—but rather superior control of subordinate labour. Animated by fossil fuels, capital could concentrate production at the most profitable sites and during the most convenient hours, as it continues to do today. Sweeping from nineteenth-century Manchester to the emissions explosion in China, from the original triumph of coal to the stalled shift to renewables, this study hones in on the burning heart of capital and demonstrates, in unprecedented depth, that turning down the heat will mean a radical overthrow of the current economic order.

    P. Putnam--a feat that would not be duplicated for another forty years. Likewise, while many remember the oil embargo of the 1970s, few are aware that it led to a corresponding explosion in green-technology research that was only derailed when energy prices later dropped.In other words: We've been here before. Although we may have failed, America has had the chance to put our world on a more sustainable path. Americans have, in fact, been inventing green for more than a century.Half compendium of lost opportunities, half hopeful look toward the future, Powering the Dream tells the stories of the brilliant, often irascible inventors who foresaw our current problems, tried to invent cheap and energy renewable solutions, and drew the blueprint for a green future.

    It is also an attempt to predict how, under cover of shocks and crises, it could get a lot worse. And it’s a plan for how, if we keep our heads, we might just be able to flip the script and arrive at a radically better future.”–From the Introduction Donald Trump’s takeover of the White House is a dangerous escalation in a world of cascading crises. His reckless agenda—including a corporate coup in government, aggressive scapegoating and warmongering, and sweeping aside climate science to set off a fossil fuel frenzy—will generate waves of disasters and shocks to the economy, national security, and the environment. Acclaimed journalist, activist, and bestselling author Naomi Klein has spent two decades studying political shocks, climate change, and “brand bullies.” From this unique perspective, she argues that Trump is not an aberration but a logical extension of the worst, most dangerous trends of the past half-century—the very conditions that have unleashed a rising tide of white nationalism the world over. It is not enough, she tells us, to merely resist, to say “no.” Our historical moment demands more: a credible and inspiring “yes,” a roadmap to reclaiming the populist ground from those who would divide us—one that sets a bold course for winning the fair and caring world we want and need. This timely, urgent book from one of our most influential thinkers offers a bracing positive shock of its own, helping us understand just how we got here, and how we can, collectively, come together and heal.

    Along the way, she meets biologists who are trying to preserve the world's rarest fish, which lives in a single tiny pool in the middle of the Mojave; engineers who are turning carbon emissions to stone in Iceland; Australian researchers who are trying to develop a super coral that can survive on a hotter globe; and physicists who are contemplating shooting tiny diamonds into the stratosphere to cool the earth.One way to look at human civilization, says Kolbert, is as a ten-thousand-year exercise in defying nature. In The Sixth Extinction, she explored the ways in which our capacity for destruction has reshaped the natural world. Now she examines how the very sorts of interventions that have imperiled our planet are increasingly seen as the only hope for its salvation.