Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with - and perished from - for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. From the Persian Queen Atossa, whose Greek slave cut off her malignant breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee’s own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive—and to increase our understanding of this iconic disease. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

    Suddenly Clarkston's streets were filled with women wearing the hijab, the smells of cumin and curry, and kids of all colours playing football in any open space they could find. Among them was Luma Mufleh, a Jordanian woman who founded a youth football team to unify Clarkston's refugee children and keep them off the streets. These kids named themselves the Fugees.Outcasts United follows a pivotal season in the life of the Fugees and their charismatic coach. Warren St. John documents the lives of a diverse group of young people as they miraculously coalesce into a band of brothers, while also drawing a fascinating portrait of a fading American town struggling to accommodate its new arrivals. At the centre of the story is fiery Coach Luma, who relentlessly drives her players to success on the football field while holding together their lives—and the lives of their families—in the face of a series of daunting challenges.This fast-paced chronicle of a single season is a complex and inspiring tale of a small town becoming a global community—and an account of the ingenious and complicated ways we create a home in a changing world.

    All four of the girls have grown up in the United States, all four want to make it into college and succeed, but only two have immigration papers. Meanwhile, after a Mexican immigrant shoots and kills a local police officer, Colorado becomes the place where national argu- ments over immigration rage most fiercely. As the girls’ lives play out against this backdrop of intense debate over whether they have any right to live here, readers will gain remarkable insight into both the power players and the most vulnerable members of society as they grapple with understanding one of the most complicated social issues of our times.Moving, timely, and passionately told, Just Like Us is a riv- eting story about girlhood, friendship, identity, and survival.

    But is it possible America's most troubling impact on the globalizing world has yet to be accounted for? In "Crazy Like Us," Ethan Watters reveals that the most devastating consequence of the spread of American culture has not been our golden arches or our bomb craters but our bulldozing of the human psyche itself: We are in the process of homogenizing the way the world goes mad. America has been the world leader in generating new mental health treatments and modern theories of the human psyche. We export our psychopharmaceuticals packaged with the certainty that our biomedical knowledge will relieve the suffering and stigma of mental illness. We categorize disorders, thereby defining mental illness and health, and then parade these seemingly scientific certainties in front of the world. The blowback from these efforts is just now coming to light: It turns out that we have not only been changing the way the world talks about and treats mental illness -- we have been changing the mental illnesses themselves.For millennia, local beliefs in different cultures have shaped the experience of mental illness into endless varieties." Crazy Like Us" documents how American interventions have discounted and worked to change those indigenous beliefs, often at a dizzying rate. Over the last decades, mental illnesses popularized in America have been spreading across the globe with the speed of contagious diseases. Watters travels from China to Tanzania to bring home the unsettling conclusion that the virus is us: As we introduce Americanized ways of treating mental illnesses, we are in fact spreading the diseases.In post-tsunami Sri Lanka, Watters reports on the Western trauma counselors who, in their rush to help, inadvertently trampled local expressions of grief, suffering, and healing. In Hong Kong, he retraces the last steps of the teenager whose death sparked an epidemic of the American version of anorexia nervosa. Watters reveals the truth about a multi-million-dollar campaign by one of the world's biggest drug companies to change the Japanese experience of depression -- literally marketing the disease along with the drug.But this book is not just about the damage we've caused in faraway places. Looking at our impact on the psyches of people in other cultures is a gut check, a way of forcing ourselves to take a fresh look at our own beliefs about mental health and healing. When we examine our assumptions from a farther shore, we begin to understand how our own culture constantly shapes and sometimes creates the mental illnesses of our time. By setting aside our role as the world's therapist, we may come to accept that we have as much to learn from other cultures' beliefs about the mind as we have to teach.

    Tender, generous and often religiously devout, they speak with eloquence and honesty about the poverty and racial isolation that have wounded but not hardened them. The book does not romanticize or soften the effects of violence and sickness. One fourth of the child-bearing women in the neighborhoods where these children live test positive for HIV. Pediatric AIDs, life-consuming fires and gang rivalries take a high toll. Several children die during the year in which this narrative takes place.A gently written work, Amazing Grace asks questions that are at once political and theological. What is the value of a child's life? What exactly do we plan to do with those whom we appear to have defined as economically and humanly superfluous? How cold -- how cruel, how tough -- do we dare be?

    Operations on the brain carry grave risks. Every day, leading neurosurgeon Henry Marsh must make agonizing decisions, often in the face of great urgency and uncertainty.If you believe that brain surgery is a precise and exquisite craft, practiced by calm and detached doctors, this gripping, brutally honest account will make you think again. With astonishing compassion and candor, Marsh reveals the fierce joy of operating, the profoundly moving triumphs, the harrowing disasters, the haunting regrets, and the moments of black humor that characterize a brain surgeon's life.Do No Harm provides unforgettable insight into the countless human dramas that take place in a busy modern hospital. Above all, it is a lesson in the need for hope when faced with life's most difficult decisions.

    The case exemplifies how the death penalty in America is a direct descendant of lynching — a system that treats the rich and guilty better than the poor and innocent.

    James McBride, journalist, musician and son, explores his mother's past, as well as his own upbringing and heritage, in a poignant and powerful debut, The Color Of Water: A Black Man's Tribute to His White Mother. The son of a black minister and a woman who would not admit she was white, James McBride grew up in "orchestrated chaos" with his eleven siblings in the poor, all-black projects of Red Hook, Brooklyn. "Mommy," a fiercely protective woman with "dark eyes full of pep and fire," herded her brood to Manhattan's free cultural events, sent them off on buses to the best (and mainly Jewish) schools, demanded good grades and commanded respect. As a young man, McBride saw his mother as a source of embarrassment, worry, and confusion--and reached thirty before he began to discover the truth about her early life and long-buried pain. In The Color of Water, McBride retraces his mother's footsteps and, through her searing and spirited voice, recreates her remarkable story. The daughter of a failed itinerant Orthodox rabbi, she was born Rachel Shilsky (actually Ruchel Dwara Zylska) in Poland on April 1, 1921. Fleeing pogroms, her family emigrated to America and ultimately settled in Suffolk, Virginia, a small town where anti-Semitism and racial tensions ran high. With candor and immediacy, Ruth describes her parents' loveless marriage; her fragile, handicapped mother; her cruel, sexually-abusive father; and the rest of the family and life she abandoned. At seventeen, after fleeing Virginia and settling in New York City, Ruth married a black minister and founded the all-black New Brown Memorial Baptist Church in her Red Hook living room. "God is the color of water," Ruth McBride taught her children, firmly convinced that life's blessings and life's values transcend race. Twice widowed, and continually confronting overwhelming adversity and racism, Ruth's determination, drive and discipline saw her dozen children through college--and most through graduate school. At age 65, she herself received a degree in social work from Temple University. Interspersed throughout his mother's compelling narrative, McBride shares candid recollections of his own experiences as a mixed-race child of poverty, his flirtations with drugs and violence, and his eventual self-realization and professional success. The Color of Water touches readers of all colors as a vivid portrait of growing up, a haunting meditation on race and identity, and a lyrical valentine to a mother from her son.

    Communities where heroin had never been seen before—from Charlotte, NC and Huntington, WVA, to Salt Lake City and Portland, OR—were overrun with it. Local police and residents were stunned. How could heroin, long considered a drug found only in the dense, urban environments along the East Coast, and trafficked into the United States by enormous Colombian drug cartels, be so incredibly ubiquitous in the American heartland? Who was bringing it here, and perhaps more importantly, why were so many townspeople suddenly eager for the comparatively cheap high it offered?With the same dramatic drive of El Narco and Methland, Sam Quinones weaves together two classic tales of American capitalism: The stories of young men in Mexico, independent of the drug cartels, in search of their own American Dream via the fast and enormous profits of trafficking cheap black-tar heroin to America’s rural and suburban addicts; and that of Purdue Pharma in Stamford, Connecticut, determined to corner the market on pain with its new and expensive miracle drug, Oxycontin; extremely addictive in its own right. Quinones illuminates just how these two stories fit together as cause and effect: hooked on costly Oxycontin, American addicts were lured to much cheaper black tar heroin and its powerful and dangerous long-lasting high. Embroiled alongside the suppliers and buyers are DEA agents, local, small-town sheriffs, and the US attorney from eastern Virginia whose case against Purdue Pharma and Oxycontin made him an enemy of the Bush-era Justice Department, ultimately stalling and destroying his career in public service.Dreamland is a scathing and incendiary account of drug culture and addiction spreading to every part of the American landscape.

    But while these workers, who leave their rural towns to find jobs in China's cities, are the driving force behind China's growing economy, little is known about their day-to-day lives or the sociological significance of this massive movement. In Factory Girls, Leslie T. Chang tells the story of these workers primarily through the lives of two young women whom she follows over the course of three years. Chang vividly portrays a world where you can lose your boyfriend and your friends with the loss of a cell phone; where lying about your age, your education, and your work experience is often a requisite for getting ahead; where a few computer or English lessons can catapult you into a completely different social class. Throughout this affecting portrait of migrant life, Chang also interweaves the story of her own family's migrations, within China and to the West, providing a historical frame of reference for her investigation. At a time when the Olympics will have shifted the world's focus to China, Factory Girls offers a previously untold story about the immense population of unknown women who work countless hours, often in hazardous conditions, to provide us with the material goods we take for granted. A book of global significance, it demonstrates how the movement from rural villages to cities is remaking individual lives and the fates of families, transforming our world much as immigration to America's shores remade our own society a century ago.

    But wealth and position could not shield Adeline from a childhood of appalling emotional abuse at the hands of a cruel and manipulative Eurasian stepmother. Determined to survive through her enduring faith in family unity, Adeline struggled for independence as she moved from Hong Kong to England and eventually to the United States to become a physician and writer.A compelling, painful, and ultimately triumphant story of a girl's journey into adulthood, Adeline's story is a testament to the most basic of human needs: acceptance, love, and understanding. With a powerful voice that speaks of the harsh realities of growing up female in a family and society that kept girls in emotional chains, Falling Leaves is a work of heartfelt intimacy and a rare authentic portrait of twentieth-century China.

    Everett, then a Christian missionary, arrived among the Pirahã in 1977–with his wife and three young children–intending to convert them. What he found was a language that defies all existing linguistic theories and reflects a way of life that evades contemporary understanding: The Pirahã have no counting system and no fixed terms for color. They have no concept of war or of personal property. They live entirely in the present. Everett became obsessed with their language and its cultural and linguistic implications, and with the remarkable contentment with which they live–so much so that he eventually lost his faith in the God he’d hoped to introduce to them. Over three decades, Everett spent a total of seven years among the Pirahã, and his account of this lasting sojourn is an engrossing exploration of language that questions modern linguistic theory. It is also an anthropological investigation, an adventure story, and a riveting memoir of a life profoundly affected by exposure to a different culture. Written with extraordinary acuity, sensitivity, and openness, it is fascinating from first to last, rich with unparalleled insight into the nature of language, thought, and life itself.

    As Islamic morality squads staged arbitrary raids in Tehran, fundamentalists seized hold of the universities, and a blind censor stifled artistic expression, the girls in Azar Nafisi's living room risked removing their veils and immersed themselves in the worlds of Jane Austen, F. Scott Fitzgerald, Henry James, and Vladimir Nabokov. In this extraordinary memoir, their stories become intertwined with the ones they are reading. Reading Lolita in Tehran is a remarkable exploration of resilience in the face of tyranny and a celebration of the liberating power of literature.

    He writes about families coping with deafness, dwarfism, Down's syndrome, autism, schizophrenia, or multiple severe disabilities; with children who are prodigies, who are conceived in rape, who become criminals, who are transgender. While each of these characteristics is potentially isolating, the experience of difference within families is universal, and Solomon documents triumphs of love over prejudice in every chapter.All parenting turns on a crucial question: to what extent should parents accept their children for who they are, and to what extent they should help them become their best selves. Drawing on ten years of research and interviews with more than three hundred families, Solomon mines the eloquence of ordinary people facing extreme challenges.Elegantly reported by a spectacularly original and compassionate thinker, Far from the Tree explores how people who love each other must struggle to accept each other—a theme in every family’s life.

    Over the next decade he built fifty-five schools—especially for girls—that offer a balanced education in one of the most isolated and dangerous regions on earth. As it chronicles Mortenson’s quest, which has brought him into conflict with both enraged Islamists and uncomprehending Americans, Three Cups of Tea combines adventure with a celebration of the humanitarian spirit.