Albert-László Barabási, the nation’s foremost expert in the new science of networks and author of Bursts, takes us on an intellectual adventure to prove that social networks, corporations, and living organisms are more similar than previously thought. Grasping a full understanding of network science will someday allow us to design blue-chip businesses, stop the outbreak of deadly diseases, and influence the exchange of ideas and information. Just as James Gleick and the Erdos–Rényi model brought the discovery of chaos theory to the general public, Linked tells the story of the true science of the future and of experiments in statistical mechanics on the internet, all vital parts of what would eventually be called the Barabási–Albert model.

    A new mother is admitted with incessant visions of harming her child. A recent graduate, dressed in a tunic and declaring that love emanates from everything around him, is brought to A&E by his alarmed girlfriend. These are among the patients new physician Christine Montross meets during rounds at her hospital’s locked inpatient ward – and who we meet as she struggles to understand the mysteries of the mind, most especially when the tools of modern medicine are failing us. Beautifully written and deeply felt, Falling into the Fire is an intimate portrait of psychiatry and a moving reminder, in the words of the New York Times, of 'our fragile, shared humanity'

    If America could send a man to the moon, shouldn’t the best surgeons in the world be able to build an artificial heart? In Ticker, Texas Monthly executive editor and two time National Magazine Award winner Mimi Swartz shows just how complex and difficult it can be to replicate one of nature’s greatest creations. Part investigative journalism, part medical mystery, Ticker is a dazzling story of modern innovation, recounting fifty years of false starts, abysmal failures and miraculous triumphs, as experienced by one the world’s foremost heart surgeons, O.H. “Bud” Frazier, who has given his life to saving the un-savable. His journey takes him from a small town in west Texas to one of the country’s most prestigious medical institutions, The Texas Heart Institute, from the halls of Congress to the animal laboratories where calves are fitted with new heart designs. The roadblocks to success —medical setbacks, technological shortcomings, government regulations – are immense. Still, Bud and his associates persist, finding inspiration in the unlikeliest of places. A field beside the Nile irrigated by an Archimedes screw. A hardware store in Brisbane, Australia. A seedy bar on the wrong side of Houston. Until post WWII, heart surgery did not exist. Ticker provides a riveting history of the pioneers who gave their all to the courageous process of cutting into the only organ humans cannot live without. Heart surgeons Michael DeBakey and Denton Cooley, whose feud dominated the dramatic beginnings of heart surgery. Christian Barnaard, who changed the world overnight by performing the first heart transplant. Inventor Robert Jarvik, whose artificial heart made patient Barney Clark a worldwide symbol of both the brilliant promise of technology and the devastating evils of experimentation run amuck. Rich in supporting players, Ticker introduces us to Bud’s brilliant colleagues in his quixotic quest to develop an artificial heart: Billy Cohn, the heart surgeon and inventor who devotes his spare time to the pursuit of magic and music; Daniel Timms, the Brisbane biomedical engineer whose design of a lightweight, pulseless heart with but a single moving part offers a new way forward. And, as government money dries up, the unlikeliest of backers, Houston’s furniture king, Mattress Mack. In a sweeping narrative of one man’s obsession, Swartz raises some of the hardest questions of the human condition. What are the tradeoffs of medical progress? What is the cost, in suffering and resources, of offering patients a few more months, or years of life? Must science do harm to do good? Ticker takes us on an unforgettable journey into the power and mystery of the human heart.

    Like Jared Diamond's Guns, Germs and Steel, Mapping Human History is a groundbreaking synthesis of science and history. Drawing on a wide range of sources, including the latest genetic research, linguistic evidence, and archaeological findings, Olson reveals the surprising unity among modern humans and "demonstrates just how naive some of our ideas about our human ancestry have been" (Discover).Olson offers a genealogy of all humanity, explaining, for instance, why everyone can claim Julius Caesar and Confucius as forebears. Olson also provides startling new perspectives on the invention of agriculture, the peopling of the Americas, the origins of language, the history of the Jews, and more. An engaging and lucid account, Mapping Human History will forever change how we think about ourselves and our relations with others.

    What happened, how it happened, and what it means to you today. A colorful cast of characters whose discoveries were often driven not only by personal tragedy, curiosity, and hard work, but petty bickering, dumb luck, and a healthy dose of humor. For anyone interested in science, medicine, and beyond... Why are you alive right now? Chances are, you owe your life to one of the remarkable medical discoveries in this book. Maybe it was vaccines. Or antibiotics. Or X-rays. Revolutionary medical breakthroughs like these haven’t just changed the way we treat disease, they’ve transformed how we understand ourselves and the world we live in. In Breakthrough!, Jon Queijo tells the hidden stories behind 10 of history’s most amazing medical discoveries. This isn’t dry history: These are life-and-death mysteries uncovered, tales of passionate, often-mocked individuals who stood their ground and were proven right. From germs to genetics, the ancient Hippocrates to the cutting edge, these are stories that have changed the world—and, quite likely, saved your life.

    "If you want to change the world in some big way," he says, "that's where you should start-biological molecules." The most disruptive force on the planet resides in DNA. Biotech companies and academic researchers are just beginning to unlock the potential of piecing together life from scratch. Champions of synthetic biology believe that turning genetic code into Lego-like blocks to build never-before-seen organisms could solve the thorniest challenges in medicine, energy, and environmental protection. But as the hackers who cracked open the potential of the personal computer and the Internet proved, the most revolutionary discoveries often emerge from out-of-the-way places, forged by brilliant outsiders with few resources besides boundless energy and great ideas. In "Biopunk," Marcus Wohlsen chronicles a growing community of DIY scientists working outside the walls of corporations and universities who are committed to democratizing DNA the way the Internet did information. The "biohacking" movement, now in its early, heady days, aims to unleash an outbreak of genetically modified innovation by making the tools and techniques of biotechnology accessible to everyone. Borrowing their idealism from the worlds of open-source software, artisinal food, Internet startups, and the Peace Corps, biopunks are devoted advocates for open-sourcing the basic code of life. They believe in the power of individuals with access to DNA to solve the world's biggest problems. You'll meet a new breed of hackers who aren't afraid to get their hands wet, from entrepreneurs who aim to bring DNA-based medical tools to the poorest of the poor to a curious tinkerer who believes a tub of yogurt and a jellyfish gene could protect the world's food supply. These biohackers include: -A duo who started a cancer drug company in their kitchen -A team who built an open-source DNA copy machine -A woman who developed a genetic test in her apartment for a deadly disease that had stricken her family Along with the potential of citizen science to bring about disruptive change, Wohlsen explores the risks of DIY bioterrorism, the possibility of genetic engineering experiments gone awry, and whether the ability to design life from scratch on a laptop might come sooner than we think.

    If you or someone you love is struggling with fibromyalgia, her new book, The Fibromyalgia Advocate, offers a wealth of practical suggestions for dealing with an often skeptical medical establishment and getting the help and support you need.

    In Think Smart, the renowned neuropsychiatrist and bestselling author Dr. Richard Restak details how each of us can improve and tone our body's most powerful organ: the brain. As a renowned expert on the brain, Restak knows that in the last five years there have been exciting new scientific discoveries about the brain and its performance. So he's asked his colleagues-many of them the world's leading brain scientists and researchers-one important question: What can I do to help my brain work more efficiently? Their surprising-and remarkably feasible-answers are at the heart of Think Smart. Restak combines advice culled from cutting-edge research with brain-tuning exercises to show how individuals of any age can make their brain work more effectively. In the same accessible prose that made Mozart's Brain and the Fighter Pilot a New York Times bestseller, Restak presents a wide array of practical recommendations about a variety of topics, including the crucial role sleep plays in boosting creativity, the importance of honing sensory memory, and the neuron- firing benefits of certain foods. In Think Smart, the "wise, witty, and ethical Restak" (says the Smithsonian Institution) offers readers helpful suggestions for fighting neurological decline that will put every reader on the path to building a healthier, more limber brain.

    In Decoding the Universe, Charles Seife draws on his gift for making cutting-edge science accessible to explain how this new tool is deciphering everything from the purpose of our DNA to the parallel universes of our Byzantine cosmos. The result is an exhilarating adventure that deftly combines cryptology, physics, biology, and mathematics to cast light on the new understanding of the laws that govern life and the universe.

    Claims that climate change isn't settled science, that evolution is "only a theory," and that scientists are conspiring to keep the truth about vaccines from the public are staples of some politicians' rhetorical repertoire. Defenders of science often point to its discoveries (penicillin! relativity!) without explaining exactly why scientific claims are superior. In this book, Lee McIntyre argues that what distinguishes science from its rivals is what he calls "the scientific attitude"--caring about evidence and being willing to change theories on the basis of new evidence. The history of science is littered with theories that were scientific but turned out to be wrong; the scientific attitude reveals why even a failed theory can help us to understand what is special about science.McIntyre offers examples that illustrate both scientific success (a reduction in childbed fever in the nineteenth century) and failure (the flawed "discovery" of cold fusion in the twentieth century). He describes the transformation of medicine from a practice based largely on hunches into a science based on evidence; considers scientific fraud; examines the positions of ideology-driven denialists, pseudoscientists, and "skeptics" who reject scientific findings; and argues that social science, no less than natural science, should embrace the scientific attitude. McIntyre argues that the scientific attitude--the grounding of science in evidence--offers a uniquely powerful tool in the defense of science.

    Acclaimed technologist and inventor Amir Husain explains how we can live amidst the coming age of sentient machines and artificial intelligence—and not only survive, but thrive.Artificial “machine” intelligence is playing an ever-greater role in our society. We are already using cruise control in our cars, automatic checkout at the drugstore, and are unable to live without our smartphones. The discussion around AI is polarized; people think either machines will solve all problems for everyone, or they will lead us down a dark, dystopian path into total human irrelevance. Regardless of what you believe, the idea that we might bring forth intelligent creation can be intrinsically frightening. But what if our greatest role as humans so far is that of creators? Amir Husain, a brilliant inventor and computer scientist, argues that we are on the cusp of writing our next, and greatest, creation myth. It is the dawn of a new form of intellectual diversity, one that we need to embrace in order to advance the state of the art in many critical fields, including security, resource management, finance, and energy. “In The Sentient Machine, Husain prepares us for a brighter future; not with hyperbole about right and wrong, but with serious arguments about risk and potential” (Dr. Greg Hyslop, Chief Technology Officer, The Boeing Company). He addresses broad existential questions surrounding the coming of AI: Why are we valuable? What can we create in this world? How are we intelligent? What constitutes progress for us? And how might we fail to progress? Husain boils down complex computer science and AI concepts into clear, plainspoken language and draws from a wide variety of cultural and historical references to illustrate his points. Ultimately, Husain challenges many of our societal norms and upends assumptions we hold about “the good life.”

    Guyton & Hall's Textbook of Medical Physiology covers all of the major systems in the human body, while emphasizing system interaction, homeostasis, and pathophysiology. This very readable, easy-to-follow, and thoroughly updated, 11th Edition features a new full-color layout, short chapters, clinical vignettes, and shaded summary tables that allow for easy comprehension of the material.The smart way to study!Elsevier titles with STUDENT CONSULT will help you master difficult concepts and study more efficiently in print and online! Perform rapid searches. Integrate bonus content from other disciplines. Download text to your handheld device. And a lot more. Each STUDENT CONSULT title comes with full text online, a unique image library, case studies, USMLE style questions, and online note-taking to enhance your learning experience.Presents short, easy-to-read chapters in keeping with the Guyton and Hall tradition.Provides shaded summary tables for easy reference.Includes clinical vignettes, which allow readers to see core concepts applied to real-life situations.Offers specific discussions of pathophysiology in most clinical areas of medicine.Ensures a strong grasp of physiology concepts through well-illustrated discussions of the most essential principles.Now in full color! Offers access to the full text and other valuable features online via the STUDENT CONSULT website.Uses full-color illustrations throughout, including 486 figures, 277 charts and graphs, 100 brand-new line drawings, and 36 ECGs.Features a new full-color design that makes information more engaging and even easier to read.Updated throughout to reflect the latest knowledge in the field.

    Right? Wrong, says Alex Rosenberg in How History Gets Things Wrong. Feeling especially well-informed after reading a book of popular history on the best-seller list? Don't. Narrative history is always, always wrong. It's not just incomplete or inaccurate but deeply wrong, as wrong as Ptolemaic astronomy. We no longer believe that the earth is the center of the universe. Why do we still believe in historical narrative? Our attachment to history as a vehicle for understanding has a long Darwinian pedigree and a genetic basis. Our love of stories is hard-wired. Neuroscience reveals that human evolution shaped a tool useful for survival into a defective theory of human nature.Stories historians tell, Rosenberg continues, are not only wrong but harmful. Israel and Palestine, for example, have dueling narratives of dispossession that prevent one side from compromising with the other. Henry Kissinger applied lessons drawn from the Congress of Vienna to American foreign policy with disastrous results. Human evolution improved primate mind reading—the ability to anticipate the behavior of others, whether predators, prey, or cooperators—to get us to the top of the African food chain. Now, however, this hard-wired capacity makes us think we can understand history—what the Kaiser was thinking in 1914, why Hitler declared war on the United States—by uncovering the narratives of what happened and why. In fact, Rosenberg argues, we will only understand history if we don't make it into a story.

    He was five inches shorter and 65 pounds lighter than the suspect described by the victim, but at trial a lab analyst testified that his DNA was found at the crime scene. His case looked like many others -- arrest, swab, match, conviction. But there was just one problem -- Sutton was innocent. We think of DNA forensics as an infallible science that catches the bad guys and exonerates the innocent. But when the science goes rogue, it can lead to a gross miscarriage of justice. Erin Murphy exposes the dark side of forensic DNA testing: crime labs that receive little oversight and produce inconsistent results; prosecutors who push to test smaller and poorer-quality samples, inviting error and bias; law-enforcement officers who compile massive, unregulated, and racially skewed DNA databases; and industry lobbyists who push policies of "stop and spit." DNA testing is rightly seen as a transformative technological breakthrough, but we should be wary of placing such a powerful weapon in the hands of the same broken criminal justice system that has produced mass incarceration, privileged government interests over personal privacy, and all too often enforced the law in a biased or unjust manner. Inside the Cell exposes the truth about forensic DNA, and shows us what it will take to harness the power of genetic identification in service of accuracy and fairness.

    In this much-anticipated book, Michael Tomasello weaves his twenty years of comparative studies of humans and great apes into a compelling argument that cooperative social interaction is the key to our cognitive uniqueness. Once our ancestors learned to put their heads together with others to pursue shared goals, humankind was on an evolutionary path all its own.Tomasello argues that our prehuman ancestors, like today's great apes, were social beings who could solve problems by thinking. But they were almost entirely competitive, aiming only at their individual goals. As ecological changes forced them into more cooperative living arrangements, early humans had to coordinate their actions and communicate their thoughts with collaborative partners. Tomasello's "shared intentionality hypothesis" captures how these more socially complex forms of life led to more conceptually complex forms of thinking. In order to survive, humans had to learn to see the world from multiple social perspectives, to draw socially recursive inferences, and to monitor their own thinking via the normative standards of the group. Even language and culture arose from the preexisting need to work together. What differentiates us most from other great apes, Tomasello proposes, are the new forms of thinking engendered by our new forms of collaborative and communicative interaction.A Natural History of Human Thinking is the most detailed scientific analysis to date of the connection between human sociality and cognition.