The Art of Game Design: A Book of Lenses shows that the same basic principles of psychology that work for board games, card games and athletic games also are the keys to making top-quality video games. Good game design happens when you view your game from many different perspectives, or lenses. While touring through the unusual territory that is game design, this book gives the reader one hundred of these lenses—one hundred sets of insightful questions to ask yourself that will help make your game better. These lenses are gathered from fields as diverse as psychology, architecture, music, visual design, film, software engineering, theme park design, mathematics, writing, puzzle design, and anthropology. Anyone who reads this book will be inspired to become a better game designer—and will understand how to do it.

    The Eighth Edition has been thoroughly revised and updated and is available in both print and e-book formats.Janeway s Immunobiology continues to set the standard for currency and authority with its clear writing style and organization, uniform art program, and scientific accuracy. It presents a consistent point of view throughout that of the host s interaction with an environment containing many species of potentially harmful microorganisms. The full-color art program is conceptually coherent and illustrates the processes and mechanisms underlying the concepts in the text. The 16 chapters in this readable, accessible textbook are organized and presented in such a way as to help deliver a complete one-semester immunology course, beginning with innate immunity, then moving to adaptive immunity, and ending with applied clinical immunology.Discussion questions are provided at the end of Chapters 2 to 16. These questions can be used for review, or as the basis for discussion in class or in informal study groups. Summaries conclude each section and each chapter. As in previous editions, a caduceus icon in the margins indicates topics which are correlated to Case Studies in Immunology, Sixth Edition by Geha and Notarangelo.New in the Eighth EditionInnate immunity has been updated and expanded and is now presented in two separate chapters (Chapters 2 and 3), as well as being further emphasized in the rest of the textbook. Chapter 2 covers antimicrobial peptides and the complement system, and Chapter 3 deals with cellular innate receptors and cell-mediated innate immunity (e.g. TLRs, phagocytosis, NK cells, interferon production, innate-like lymphocytes). The section on complement has been reworked and reconceived explaining the lectin pathway first making it easier to teach by placing it into the context of innate recognition. Evolution is now incorporated throughout the text, helping students see similar strategies used by different organisms. The text and figures of Chapter 7 Signaling Through Immune System Receptors have been revised to present a cohesive synthesis of signaling for immunology, focusing on improved illustration of antigen recognition signaling and lymphocyte activation. Signaling through other receptors is dealt with wherever appropriate throughout the book. Updated chapter on B-cell immune responses (Chapter 10), especially on trafficking of B cells in peripheral lymphoid organs (e.g. lymph nodes) and the locations at which they encounter antigen. Coverage of mucosal immunity (Chapter 12) has been brought up to date, including responses to the commensal microbiota and the role of specialized dendritic cells and the regulatory T cells in maintaining tolerance to food antigens and commensal bacteria. Chapter 13, Failures of Host Defense Mechanisms, has been reorganized and revised to structure an understanding of primary immunodeficiencies in the context of developmental pathways. Chapter 16, Manipulation of the Immune Response, has been heavily revised to include a greater emphasis on clinical issues and a complete update of immunotherapeutics and vaccines. Many new and revised figures illustrate the processes and mechanisms underlying the concepts presented in the text. The icons used have been updated and expanded to incorporate a new emphasis on signaling pathways. New references have been added throughout the text.

    Objects are introduced early, right after control structures and before arrays and pointers. The STL string class is used throughout. As with all Gaddis books, there is a strong emphasis on problem solving and program design, a careful step-by-step introduction of each new topic, clear and easy to read code listings, concise and practical real world examples, and an abundance of exercises in each chapter.

    If you use Python, even as a beginner, this book will teach you practical ways to build your own machine learning solutions. With all the data available today, machine learning applications are limited only by your imagination.You'll learn the steps necessary to create a successful machine-learning application with Python and the scikit-learn library. Authors Andreas Muller and Sarah Guido focus on the practical aspects of using machine learning algorithms, rather than the math behind them. Familiarity with the NumPy and matplotlib libraries will help you get even more from this book.With this book, you'll learn:Fundamental concepts and applications of machine learningAdvantages and shortcomings of widely used machine learning algorithmsHow to represent data processed by machine learning, including which data aspects to focus onAdvanced methods for model evaluation and parameter tuningThe concept of pipelines for chaining models and encapsulating your workflowMethods for working with text data, including text-specific processing techniquesSuggestions for improving your machine learning and data science skills

    The R language is recognised as one of the most powerful and flexible statistical software packages, and it enables the user to apply many statistical techniques that would be impossible without such software to help implement such large data sets.

    Rich Stevens describes more than 200 system calls and functions; since he believes the best way to learn code is to read code, a brief example accompanies each description.Building upon information presented in the first 15 chapters, the author offers chapter-long examples teaching you how to create a database library, a PostScript printer driver, a modem dialer, and a program that runs other programs under a pseudo terminal. To make your analysis and understanding of this code even easier, and to allow you to modify it, all of the code in the book is available via UUNET.A 20-page appendix provides detailed function prototypes for all the UNIX, POSIX, and ANSI C functions that are described in the book, and lists the page on which each prototype function is described in detail. Additional tables throughout the text and a thorough index make Advanced Programming in the UNIX Environment an invaluable reference tool that all UNIX programmers - beginners to experts - w

    Subsequent sections deal with integrating factors; dilution and accretion problems; linearization of first order systems; Laplace Transforms; Newton's Interpolation Formulas, more.

    Not only does this Bible give you a quick refresher on the structure of open-source Linux software, it also shows you how to bypass the hefty graphical user interface on Linux systems and start interacting the fast and efficient way?with command lines and automated scripts. You'll learn how to manage files on the filesystem, start and stop programs, use databases, even do Web programming?without a GUI?with this one-stop resource.

    With countless satisfied developers, tens of thousands of freely available libraries, and continual improvements to the language and its ecosystem, modern Perl development can be easy, reliable, and fun. To take advantage of the full power of Perl 5--to become a true expert, capable of solving any problem put before you--you must understand the language. Modern Perl explains Perl 5 from theory to implementation, including Perl 5.12.

    It's available on almost every OS--if you master the techniques in this book, you'll never need another text editor. Practical Vim shows you 120 vim recipes so you can quickly learn the editor's core functionality and tackle your trickiest editing and writing tasks. Vim, like its classic ancestor vi, is a serious tool for programmers, web developers, and sysadmins. No other text editor comes close to Vim for speed and efficiency; it runs on almost every system imaginable and supports most coding and markup languages. Learn how to edit text the "Vim way:" complete a series of repetitive changes with The Dot Formula, using one keystroke to strike the target, followed by one keystroke to execute the change. Automate complex tasks by recording your keystrokes as a macro. Run the same command on a selection of lines, or a set of files. Discover the "very magic" switch, which makes Vim's regular expression syntax more like Perl's. Build complex patterns by iterating on your search history. Search inside multiple files, then run Vim's substitute command on the result set for a project-wide search and replace. All without installing a single plugin! You'll learn how to navigate text documents as fast as the eye moves--with only a few keystrokes. Jump from a method call to its definition with a single command. Use Vim's jumplist, so that you can always follow the breadcrumb trail back to the file you were working on before. Discover a multilingual spell-checker that does what it's told.Practical Vim will show you new ways to work with Vim more efficiently, whether you're a beginner or an intermediate Vim user. All this, without having to touch the mouse.What You Need: Vim version 7

    The Cell: a Molecular Approach meets this challenge by providing students with not only the current information, but also with an introduction to the experimental nature of contemporary research. Designed for use in introductory cell biology courses, The Cell presents current, comprehensive science in a readable and cohesive text that students can master in the course of one semester. The new third edition of The Cell retains the organization, themes, and special features of earlier editions, but is updated to reflect scientific advances since publication of the second edition, including progress in genome sequencing, advances in understanding transcriptional regulation and mRNA processing, use of DNA microarrays in global studies of gene expression and cancer diagnostics, advances in nuclear transport and protein trafficking, progress in understanding the regulation of programmed cell death, potential medical applications of embryonic cells, and development of oncogene-targeted treatments. Key Experimental boxes in each chapter describe seminal experiments in modern cell biology, showing the detail and background to give students a sense of doing science. Molecular Medicine boxes relate basic science to clinical practice or potential and show the excitement of molecular discovery and solutions to disease. Chapter summaries are organized in outline form corresponding to the major sections and subsections of each chapter. This section-by-section format is coupled with a list of the key terms introduced in eachsection, providing a succinct but comprehensive review of the material. The full-color art program is both pedagogically and scientifically outstanding. In addition, each chapter includes a brief chapter outline, boldfaced key terms (also defined in the glossary), and many new chapter-end questions with answers in the back of the book. With a clear focus on cell biology as an integrative theme, topics such as developmental biology, plant biology, the immune system, the nervous system, and muscle physiology are covered in their broader biological context. The book can be bundled for purchase with a special edition of Molecules, Cells, and Genes, a CD-ROM keyed to the textbook and combining the essential features of a Study Guide and Problems book.

    With step-by-step instructions, complete scripts, and expert tips to guide readers, this work gets right down to business - after grounding readers with separate discussions of first the scripting language (PHP) and then the database program (MySQL), it goes on to cover security, sessions and cookies, and using additional Web tools.

    Not only will you learn about the enterprise class features in the 9.2 release, you’ll also discover that PostgeSQL is more than just a database system—it’s also an impressive application platform.With numerous examples throughout this book, you’ll learn how to achieve tasks that are difficult or impossible in other databases. If you’re an existing PostgreSQL user, you’ll pick up gems you may have missed along the way.Learn basic administration tasks, such as role management, database creation, backup, and restoreApply the psql command-line utility and the pgAdmin graphical administration toolExplore PostgreSQL tables, constraints, and indexesLearn powerful SQL constructs not generally found in other databasesUse several different languages to write database functionsTune your queries to run as fast as your hardware will allowQuery external and variegated data sources with Foreign Data WrappersLearn how to replicate data, using built-in replication features

    With this hands-on book, you’ll learn Flask from the ground up by developing a complete social blogging application step-by-step. Author Miguel Grinberg walks you through the framework’s core functionality, and shows you how to extend applications with advanced web techniques such as database migration and web service communication.Rather than impose development guidelines as other frameworks do, Flask leaves the business of extensions up to you. If you have Python experience, this book shows you how to take advantage of that creative freedom.- Learn Flask’s basic application structure and write an example app- Work with must-have components—templates, databases, web forms, and email support- Use packages and modules to structure a large application that scales- Implement user authentication, roles, and profiles- Build a blogging feature by reusing templates, paginating item lists, and working with rich text- Use a Flask-based RESTful API to expose app functionality to smartphones, tablets, and other third-party clients- Learn how to run unit tests and enhance application performance- Explore options for deploying your web app to a production server

    This staggering amount of information—unprecedented in history—can tell us a great deal about who we are—the fears, desires, and behaviors that drive us, and the conscious and unconscious decisions we make. From the profound to the mundane, we can gain astonishing knowledge about the human psyche that less than twenty years ago, seemed unfathomable.Everybody Lies offers fascinating, surprising, and sometimes laugh-out-loud insights into everything from economics to ethics to sports to race to sex, gender and more, all drawn from the world of big data. What percentage of white voters didn’t vote for Barack Obama because he’s black? Does where you go to school effect how successful you are in life? Do parents secretly favor boy children over girls? Do violent films affect the crime rate? Can you beat the stock market? How regularly do we lie about our sex lives and who’s more self-conscious about sex, men or women?Investigating these questions and a host of others, Seth Stephens-Davidowitz offers revelations that can help us understand ourselves and our lives better. Drawing on studies and experiments on how we really live and think, he demonstrates in fascinating and often funny ways the extent to which all the world is indeed a lab. With conclusions ranging from strange-but-true to thought-provoking to disturbing, he explores the power of this digital truth serum and its deeper potential—revealing biases deeply embedded within us, information we can use to change our culture, and the questions we’re afraid to ask that might be essential to our health—both emotional and physical. All of us are touched by big data everyday, and its influence is multiplying. Everybody Lies challenges us to think differently about how we see it and the world.