We like to imagine that it’s based on evidence and the results of fair tests. In reality, those tests are often profoundly flawed. We like to imagine that doctors are familiar with the research literature surrounding a drug, when in reality much of the research is hidden from them by drug companies. We like to imagine that doctors are impartially educated, when in reality much of their education is funded by industry. We like to imagine that regulators let only effective drugs onto the market, when in reality they approve hopeless drugs, with data on side effects casually withheld from doctors and patients.All these problems have been protected from public scrutiny because they’re too complex to capture in a sound bite. But Dr. Ben Goldacre shows that the true scale of this murderous disaster fully reveals itself only when the details are untangled. He believes we should all be able to understand precisely how data manipulation works and how research misconduct on a global scale affects us. In his own words, “the tricks and distortions documented in these pages are beautiful, intricate, and fascinating in their details.” With Goldacre’s characteristic flair and a forensic attention to detail, Bad Pharma reveals a shockingly broken system and calls for something to be done. This is the pharmaceutical industry as it has never been seen before.

    . . .performs with virtuoso flair in THE QUITTER"--THE NEW YORKER"Brutally honest."--ROLLING STONE★"A searingly honest memoir. . . . Pekar's work dignifies the struggle of the average man."--PUBLISHERS WEEKLY, starred In this virtuoso graphic novel, Harvey Pekar -- whose American Book Award-winning series American Splendor was the basis for the celebrated film of the same name -- tells the story of his troubled teen years for the first time, when he would beat up any kid who looked at him wrong just to win the praise of his peers. And when he failed to impress, whether on the football team, in math class, in the Navy or on the job, he simply gave up. A true tour-de-force, THE QUITTER is the universal tale of a young man's search for himself through the frustrations, redemptions and complexities of ordinary life.With gritty, atmospheric artwork by indie-comics luminary Dean Haspiel (American Splendor, Opposable Thumbs), THE QUITTER is both Pekar's funniest and most heart-wrenching work yet, an unforgettable graphic novel for all those, like Pekar, who have tried, failed and lived to quit another day.

    health care system is in a state of disrepair, but the rabbit hole goes deeper than even the staunchest critics may realize. In Primal Prescription, authors Doug McGuff and Robert Murphy combine their expertise in economics and medicine to offer a shocking, disturbing, and ultimately enlightening view into America’s health care system. You’ll discover the real history of what went wrong with U.S. health care and insurance, and why current efforts to clean up the mess are only making things worse.But far from leaving you feeling helpless at the dismal—and sometimes deadly—state of affairs, Primal Prescription equips you with both the knowledge to understand the health care conundrum and the tools for navigating your way out of it. McGuff and Murphy offer an evidence-based “game plan” for taking control of your own medical care, protecting yourself and your loved ones regardless of what the future holds for the rest of the nation.Whether you’re currently tangled in America’s broken health care system or simply trying to avoid its clutches, Primal Prescription is a must-have resource for taking your health into your own hands.

    In a work free of technical language and jargon, Andrew Fisher covers the main ideas that have shaped metaethics from the work of G.E. Moore to the latest thinking. Written specifically for students new to this subject, Metaethics assumes no prior philosophical knowledge. It also highlights ways to avoid common errors, offers hints and tips on learning the subject, includes a glossary of core terms, and provides guidance for further study.

    Drawing on newly available papers of Jonas Salk, Albert Sabin and other key players, Oshinsky paints a suspenseful portrait of the race for the cure, weaving a dramatic tale centered on the furious rivalry between Salk and Sabin. He also tells the story of Isabel Morgan, perhaps the most talented of all polio researchers, who might have beaten Salk to the prize if she had not retired to raise a family.Oshinsky offers an insightful look at the National Foundation for Infantile Paralysis, which was founded in the 1930s by FDR and Basil O'Connor, it revolutionized fundraising and the perception of disease in America. Oshinsky also shows how the polio experience revolutionized the way in which the government licensed and tested new drugs before allowing them on the market, and the way in which the legal system dealt with manufacturers' liability for unsafe products. Finally, and perhaps most tellingly, Oshinsky reveals that polio was never the raging epidemic portrayed by the media, but in truth a relatively uncommon disease. But in baby-booming America--increasingly suburban, family-oriented, and hygiene-obsessed--the specter of polio, like the specter of the atomic bomb, soon became a cloud of terror over daily life.Both a gripping scientific suspense story and a provocative social and cultural history, Polio opens a fresh window onto postwar America.

    Improper use of antibiotics. Local warfare. Massive refugee migration. Changing social and environmental conditions around the world have fostered the spread of new and potentially devastating viruses and diseases—HIV, Lassa, Ebola, and others. Laurie Garrett takes you on a fifty-year journey through the world's battles with microbes and examines the worldwide conditions that have culminated in recurrent outbreaks of newly discovered diseases, epidemics of diseases migrating to new areas, and mutated old diseases that are no longer curable. She argues that it is not too late to take action to prevent the further onslaught of viruses and microbes, and offers possible solutions for a healthier future.

    On March 9, 1945, it created an inferno that killed over 87,500 people in Tokyo--more than died in the atomic explosions at Hiroshima or Nagasaki. It went on to incinerate sixty-four of Japan's largest cities. The Bomb got the press, but napalm did the work.After World War II, the incendiary held the line against communism in Greece and Korea--Napalm Day led the 1950 counter-attack from Inchon--and fought elsewhere under many flags. Americans generally applauded, until the Vietnam War. Today, napalm lives on as a pariah: a symbol of American cruelty and the misguided use of power, according to anti-war protesters in the 1960s and popular culture from "Apocalypse Now" to the punk band Napalm Death and British street artist Banksy. Its use by Serbia in 1994 and by the United States in Iraq in 2003 drew condemnation. United Nations delegates judged deployment against concentrations of civilians a war crime in 1980. After thirty-one years, America joined the global consensus, in 2011.Robert Neer has written the first history of napalm, from its inaugural test on the Harvard College soccer field, to a Marine Corps plan to attack Japan with millions of bats armed with tiny napalm time bombs, to the reflections of Phan Thi Kim Phuc, a girl who knew firsthand about its power and its morality.

    In fact, most of the frightening images and stereotypes surrounding fringe religious movements are traceable to the mid-nineteenth century when Mormons, Freemasons, and even Catholics were denounced for supposed ritualistic violence, fraud, and sexual depravity. But America has also been the home of an often hysterical anti-cult backlash. Jenkins offers an insightful new analysis of why cults arouse such fear and hatred both in the secular world and in mainstream churches, many of which were themselves originally regarded as cults. He argues that an accurate historical perspective is urgently needed if we are to avoid the kind of catastrophic confrontation that occurred in Waco or the ruinous prosecution of imagined Satanic cults that swept the country in the 1980s.Without ignoring genuine instances of aberrant behavior, Mystics and Messiahs goes beyond the vast edifice of myth, distortion, and hype to reveal the true characteristics of religious fringe movements and why they inspire such fierce antagonism.

    Puar brings her pathbreaking work on the liberal state, sexuality, and biopolitics to bear on our understanding of disability. Drawing on a stunning array of theoretical and methodological frameworks, Puar uses the concept of “debility”—bodily injury and social exclusion brought on by economic and political factors—to disrupt the category of disability. She shows how debility, disability, and capacity together constitute an assemblage that states use to control populations. Puar's analysis culminates in an interrogation of Israel's policies toward Palestine, in which she outlines how Israel brings Palestinians into biopolitical being by designating them available for injury. Supplementing its right to kill with what Puar calls the right to maim, the Israeli state relies on liberal frameworks of disability to obscure and enable the mass debilitation of Palestinian bodies. Tracing disability's interaction with debility and capacity, Puar offers a brilliant rethinking of Foucauldian biopolitics while showing how disability functions at the intersection of imperialism and racialized capital.

    But as Virginia DeJohn Anderson reveals in this brilliantly original account of colonists in New England and the Chesapeake region, livestockplayed a vitally important role in the settling of the New World. Livestock, Anderson writes, were a central factor in the cultural clash between colonists and Indians as well as a driving force in the expansion west. By bringing livestock across the Atlantic, colonists believed that they provided the means to realize America's potential. It was thoughtthat if the Native Americans learned to keep livestock as well, they would be that much closer to assimilating the colonists' culture, especially their Christian faith. But colonists failed to anticipate the problems that would arise as Indians began encountering free-ranging livestock at almostevery turn, often trespassing in their cornfields. Moreover, when growing populations and an expansive style of husbandry required far more space than they had expected, colonists could see no alternative but to appropriate Indian land. This created tensions that reached the boiling point with KingPhilip's War and Bacon's Rebellion. And it established a pattern that would repeat time and again over the next two centuries. A stunning account that presents our history in a truly new light, Creatures of Empire restores a vital element of our past, illuminating one of the great forces of colonization and the expansion westward.

    Many books on the plague rely on statistics to tell the story: how many people died; how farm output and trade declined. But statistics can’t convey what it was like to sit in Siena or Avignon and hear that a thousand people a day are dying two towns away. Or to have to chose between your own life and your duty to a mortally ill child or spouse. Or to live in a society where the bonds of blood and sentiment and law have lost all meaning, where anyone can murder or rape or plunder anyone else without fear of consequence.In The Great Mortality, author John Kelly lends an air of immediacy and intimacy to his telling of the journey of the plague as it traveled from the steppes of Russia, across Europe, and into England, killing 75 million people—one third of the known population—before it vanished.

    Yet despite a century of medical progress, viral and bacterial disasters continue to take us by surprise, inciting panic and dominating news cycles. From the Spanish flu to the 1924 outbreak of pneumonic plague in Los Angeles to the 1930 “parrot fever” pandemic, through the more recent SARS, Ebola, and Zika epidemics, the last one hundred years have been marked by a succession of unanticipated pandemic alarms.In The Pandemic Century, a lively account of scares both infamous and less known, Mark Honigsbaum combines reportage with the history of science and medical sociology to artfully reconstruct epidemiological mysteries and the ecology of infectious diseases. We meet dedicated disease detectives, obstructive or incompetent public health officials, and brilliant scientists often blinded by their own knowledge of bacteria and viruses. We also see how fear of disease often exacerbates racial, religious, and ethnic tensions—even though, as the epidemiologists Malik Peiris and Yi Guan write, “‘nature’ remains the greatest bioterrorist threat of all.”Like man-eating sharks, predatory pathogens are always present in nature, waiting to strike; when one is seemingly vanquished, others appear in its place. These pandemics remind us of the limits of scientific knowledge, as well as the role that human behavior and technologies play in the emergence and spread of microbial diseases.

    This pamphlet explores two important phases in the male takeover of health care: the suppression of witches in medieval Europe and the rise of the male medical profession in the United States. The authors conclude that despite efforts to exclude them, the resurgence of women as healers should be a long-range goal of the women’s movement.

    It's tempting to blame evil acts on evil people, but that leaves the rest us off the hook. Silence, after all, can perpetuate cruelty. Why We Act draws on the latest developments in psychology and neuroscience to tackle an urgent question: Why do so many of us fail to intervene when we're needed--and what would it take to make us step up?A renowned psychologist who has done pioneering research on social norms, Catherine Sanderson was inspired to write this book when a freshman in her son's dorm died twenty hours after a bad fall while drinking. There were many points along the way when a decision to seek help could have saved his life. Why did no one act sooner?Cutting-edge neuroscience offers part of the answer, showing how deviating from the group activates the same receptors in the brain that are triggered by pain. But Sanderson also points to many ways in which our faulty assumptions about what other people are thinking can paralyze us. And she shares surprisingly effective and simple strategies for resisting the pressure to conform. Moral courage, it turns out, is not innate. Small details and the right training can make a big difference. Inspiring and potentially life transforming, Why We Act reveals that while the urge to do nothing is deeply ingrained, even the most hesitant would-be bystander can learn to be a moral rebel.

    In his first novel in ten years, Dennis Cooper writes about George Miles, love, loss, addiction, suicide, and how fiction can capture these things, and how it fails to capture them. Candid and powerful, I Wished is a radical work of shifting forms. It includes appearances by Santa Claus, land artist James Turrell, sentient prairie dogs, John Wayne Gacy, Nick Drake, and George, the muse for Cooper’s acclaimed novels Closer, Frisk, Try, Guide, and Period, collectively known as “The George Miles Cycle.” In revisiting the inspiration for the Cycle, Dennis has written a masterwork: the most raw, personal, and haunted book of his career.