As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned ​a curiosity ​of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020.

    The result is an explosive book that takes us, for the first time, deep inside a shadowy, fascinating, and surreal world of unscrupulous doctors, anything-goes team directors, and athletes so relentlessly driven to succeed that they would do anything—and take any risk, physical, mental, or moral—to gain the edge they need to win.Tyler Hamilton was once one of the world’s best-liked and top-ranked cyclists—a fierce competitor renowned among his peers for his uncanny endurance and epic tolerance for pain. In the 2003 Tour de France, he finished fourth despite breaking his collarbone in the early stages—and grinding eleven of his teeth down to the nerves along the way. He started his career with the U.S. Postal Service team in the 1990s and quickly rose to become Lance Armstrong’s most trusted lieutenant, and a member of his inner circle. For the first three of Armstrong’s record seven Tour de France victories, Hamilton was by Armstrong’s side, clearing his way. But just weeks after Hamilton reached his own personal pinnacle—winning the gold medal at the 2004 Olympics—his career came to a sudden, ignominious end: He was found guilty of doping and exiled from the sport.From the exhilaration of his early, naïve days in the peloton, Hamilton chronicles his ascent to the uppermost reaches of this unforgiving sport. In the mid-1990s, the advent of a powerful new blood-boosting drug called EPO reshaped the world of cycling, and a relentless, win-at-any-cost ethos took root. Its psychological toll would drive many of the sport’s top performers to substance abuse, depression, even suicide. For the first time ever, Hamilton recounts his own battle with clinical depression, speaks frankly about the agonizing choices that go along with the decision to compete at a world-class level, and tells the story of his complicated relationship with Lance Armstrong.A journey into the heart of a never-before-seen world, The Secret Race is a riveting, courageous act of witness from a man who is as determined to reveal the hard truth about his sport as he once was to win the Tour de France.

    Nonna's writings tell the remarkable tale of how a Russian girl, born into a family that had known wealth and privileges, was exposed to the concentration camps and learned the value of human life and the importance of forgiveness.

    Her recording of Prince's Nothing Compares 2 U made her a global icon. She outraged millions when she tore up a photograph of Pope John Paul II on American television.O'Connor was unapologetic and impossible to ignore, calling out hypocrisy wherever she saw it.She has remained that way for three decades.Now, in Rememberings, O'Connor tells her story - the heartache of growing up in a family falling apart; her early forays into the Dublin music scene; her adventures and misadventures in the world of sex, drugs and rock'n'roll; the fulfilment of being a mother; her ongoing spiritual quest - and through it all, her abiding passion for music.Rememberings is intimate, replete with candid anecdotes and full of hard-won insights. It is a unique and remarkable chronicle by a unique and remarkable artist.

    When I almost died it was just after midday.When the Taliban took control of the Swat Valley in Pakistan, one girl spoke out. Malala Yousafzai refused to be silenced and fought for her right to an education.On Tuesday, October 9, 2012, when she was fifteen, she almost paid the ultimate price. She was shot in the head at point-blank range while riding the bus home from school, and few expected her to survive. Instead, Malala's miraculous recovery has taken her on an extraordinary journey from a remote valley in northern Pakistan to the halls of the United Nations in New York. At sixteen, she has become a global symbol of peaceful protest and the youngest-ever Nobel Peace Prize laureate.I Am Malala is the remarkable tale of a family uprooted by global terrorism, of the fight for girls' education, of a father who, himself a school owner, championed and encouraged his daughter to write and attend school, and of brave parents who have a fierce love for their daughter in a society that prizes sons.

    This is Maya Angelou talking from the heart, down to earth and real, but also inspiring. This is a book to treasured, a book about being in all ways a woman, about living well, about the power of the word, and about the power do spirituality to move and shape your life. Passionate, lively, and lyrical, Maya Angelou's latest unforgettable work offers a gem of truth on every page. "From the Paperback edition."

    Once married, however, she acquired a persistent pain that led to destructive drugs and patronizing psychiatry, ending in an ineffective but irrevocable surgery. There would be no children; in herself she found instead one novel, and then another.

    Early marriage and motherhood seemed to put even that dream out of reach, but fifteen years later she was a distinguished law professor with a deep understanding of why people go bankrupt. Then came the phone call that changed her life: could she come to Washington DC to help advise Congress on rewriting the bankruptcy laws?Thus began an impolite education into the bare-knuckled, often dysfunctional ways of Washington. She fought for better bankruptcy laws for ten years and lost. She tried to hold the federal government accountable during the financial crisis but became a target of the big banks. She came up with the idea for a new agency designed to protect consumers from predatory bankers and was denied the opportunity to run it. Finally, at age 62, she decided to run for elective office and won the most competitive—and watched—Senate race in the country. In this passionate, funny, rabble-rousing book, Warren shows why she has chosen to fight tooth and nail for the middle class—and why she has become a hero to all those who believe that America's government can and must do better for working families.

    But in this extraordinary autobiography, Shania reveals that she is so much more. She is Eilleen Twain, one of five children born into poverty in rural Canada, where her family often didn't have enough food to send her to school with lunch. She's the teenage girl who helped her mother and young siblings escape to a battered woman's shelter to put an end to the domestic violence in her family home. And she's the courageous twenty-two-year-old who sacrificed to keep her younger siblings together after her parents were tragically killed in a car accident.Shania Twain's life has evolved from a series of pivotal moments, and in unflinching, heartbreaking prose, Shania spares no details as she takes us through the events that have made her who she is. She recounts her difficult childhood, her parents' sudden death and its painful aftermath, her dramatic rise to stardom, her devastating betrayal by a trusted friend, and her joyful marriage to the love of her life. From these moments, she offers profound, moving insights into families, personal tragedies, making sense of one's life, and the process of healing. Shania Twain is a singular, remarkable woman who has faced enormous odds and downfalls, and her extraordinary story will provide wisdom, inspiration, and hope for almost anyone.

    Long past the years of diapers, homework, and recitals, Roger and Ginny-Boppo and Mimi to the kids-quickly reaccustomed themselves to the world of small children: bedtime stories, talking toys, playdates, nonstop questions, and nonsequential thought. Though still reeling from Amy's death, they carried on, reconstructing a family, sustaining one another, and guiding three lively, alert, and tenderhearted children through the pains and confusions of grief. As he marveled at the strength of his son-in-law, a surgeon, and the tenacity and skill of his wife, a former kindergarten teacher, Roger attended each day to 'the one household duty I have mastered'-preparing the morning toast perfectly to each child's liking. With the wit, heart, precision, and depth of understanding that has characterized his work, Roger Rosenblatt peels back the layers on this most personal of losses to create both a tribute to his late daughter and a testament to familial love. The day Amy died, Harris told Ginny and Roger, "It's impossible". Roger's story tells how a family makes the possible of the impossible.

    But through self-discipline, mental toughness, and hard work, Goggins transformed himself from a depressed, overweight young man with no future into a U.S. Armed Forces icon and one of the world's top endurance athletes. The only man in history to complete elite training as a Navy SEAL, Army Ranger, and Air Force Tactical Air Controller, he went on to set records in numerous endurance events, inspiring Outside magazine to name him "The Fittest (Real) Man in America."In Can't Hurt Me, he shares his astonishing life story and reveals that most of us tap into only 40% of our capabilities. Goggins calls this The 40% Rule, and his story illuminates a path that anyone can follow to push past pain, demolish fear, and reach their full potential.

     Michael Oher is the young man at the center of the true story depicted in "The Blind Side" movie (and book) that swept up awards and accolades. Though the odds were heavily stacked against him, Michael had a burning desire deep within his soul to break out of the Memphis inner-city ghetto and into a world of opportunity. While many people are now familiar with Oher's amazing journey, this is the first time he shares his account of his story in his own words, revealing his thoughts and feelings with details that only he knows, and offering his point of view on how anyone can achieve a better life. Looking back on how he went from being a homeless child in Memphis to playing in the NFL, Michael talks about the goals he had for himself in order to break out of the cycle of poverty, addiction, and hopelessness that trapped his family for so long. He recounts poignant stories growing up in the projects and running from child services and foster care over and over again in search of some familiarity. Eventually he grasped onto football as his ticket out of the madness and worked hard to make his dream into a reality. But Oher also knew he would not be successful alone. With his adoptive family, the Touhys, and other influential people in mind, he describes the absolute necessity of seeking out positive role models and good friends who share the same values to achieve one's dreams. Sharing untold stories of heartache, determination, courage, and love, "I Beat the Odds" is an incredibly rousing tale of one young man's quest to achieve the American dream.

    In 1969, her father, Robert Nichols, moved to Sellerstown, North Carolina, to serve as a pastor. There he found a small community eager to welcome him--with one exception. Glaring at him from pew number seven was a man obsessed with controlling the church. Determined to get rid of anyone who stood in his way, he unleashed a plan of terror that was more devastating and violent than the Nichols family could have ever imagined. Refusing to be driven away by acts of intimidation, Rebecca's father stood his ground until one night when an armed man walked into the family's kitchen . . . And Rebecca's life was shattered. If anyone had a reason to harbor hatred and seek personal revenge, it would be Rebecca. Yet The Devil in Pew Number Seven tells a different story. It is the amazing true saga of relentless persecution, one family's faith and courage in the face of it, and a daughter whose parents taught her the power of forgiveness.

    She had fallen in love and moved to Paris to pursue her dream of becoming a war correspondent. The real world she found, however, would take her into a very different kind of conflict zone.It started with an itch—first on her feet, then up her legs, like a thousand invisible mosquito bites. Next came the exhaustion, and the six-hour naps that only deepened her fatigue. Then a trip to the doctor and, a few weeks shy of her twenty-third birthday, a diagnosis: leukemia, with a 35 percent chance of survival. Just like that, the life she had imagined for herself had gone up in flames. By the time Jaouad flew home to New York, she had lost her job, her apartment, and her independence. She would spend much of the next four years in a hospital bed, fighting for her life and chronicling the saga in a column for The New York Times.When Jaouad finally walked out of the cancer ward—after three and a half years of chemo, a clinical trial, and a bone marrow transplant—she was, according to the doctors, cured. But as she would soon learn, a cure is not where the work of healing ends; it’s where it begins. She had spent the past 1,500 days in desperate pursuit of one goal—to survive. And now that she’d done so, she realized that she had no idea how to live.How would she reenter the world and live again? How could she reclaim what had been lost? Jaouad embarked—with her new best friend, Oscar, a scruffy terrier mutt—on a 100-day, 15,000-mile road trip across the country. She set out to meet some of the strangers who had written to her during her years in the hospital: a teenage girl in Florida also recovering from cancer; a teacher in California grieving the death of her son; a death-row inmate in Texas who’d spent his own years confined to a room. What she learned on this trip is that the divide between sick and well is porous, that the vast majority of us will travel back and forth between these realms throughout our lives. Between Two Kingdoms is a profound chronicle of survivorship and a fierce, tender, and inspiring exploration of what it means to begin again.

    Rousey shares hard-won lessons on how to be the best at what you do, including how to find fulfillment in the sacrifices, how to turn limitations into opportunities, and how to be the best on your worst day.Packed with raw emotion, drama, and wisdom this is an unforgettable book by one of the most remarkable women in the world.