But for most of human history, practically no one slept this way. Tracing sleep's transformation since the dawn of the industrial age, Reiss weaves together insights from literature, social and medical history, and cutting-edge science to show how and why we have tried and failed to tame sleep. In lyrical prose, he leads readers from bedrooms and laboratories to factories and battlefields to Henry David Thoreau's famous cabin at Walden Pond, telling the stories of troubled sleepers, hibernating peasants, sleepwalking preachers, cave-dwelling sleep researchers, slaves who led nighttime uprisings, rebellious workers, spectacularly frazzled parents, and utopian dreamers. We are hardly the first people, Reiss makes clear, to chafe against our modern rules for sleeping.A stirring testament to sleep's diversity, Wild Nights offers a profound reminder that in the vulnerability of slumber we can find our shared humanity. By peeling back the covers of history, Reiss recaptures sleep's mystery and grandeur and offers hope to weary readers: as sleep was transformed once before, so too can it change today.

    The Atlas of Disease is the first book to tell these stories in a new an innovative way, interweaving new maps with contemporary illustrations to chart some of the world's most deadly pandemics and epidemics.   In The Atlas of Disease, Sandra Hempel reveals how maps have uncovered insightful information about the history of disease, from the seventeenth century plague maps that revealed the radical idea that diseases might be carried and spread by humans, to cholera maps in the 1800s showing the disease was carried by water, right up to the AIDs epidemic in the 1980s, and the recent devastating ebola outbreak.    Crucially, The Atlas of Disease will also explore how cartographic techniques have been used to combat epidemics by revealing previously hidden patterns. These discoveries have changed the course of history, affected human evolution, stimulated advances in medicine and saved countless lives.

    Richard Rhodes follows virus hunters on three continents as they track the emergence of a deadly new brain disease that first kills cannibals in New Guinea, then cattle and young people in Britain and France—and that has already been traced to food animals in the United States. In a new afterword for the paperback, Rhodes reports the latest US and worldwide developments of a burgeoning global threat.

    This hidden army is our immune system, and without it we could not survive the eternal war between us and our microscopic enemies.Immune explores the incredible arsenal that lives within us how it knows what to attack and what to defend, and how it kills everything from the common cold to the plague bacterium. We see what happens when the immune system turns on us, and conversely how impossible life is without its protection. We learn how diseases try to evade the immune system, how they exploit vulnerabilities and even subvert it to their own advantage, and we discover how scientists are designing new drugs to harness the power of the system to advance medicine in the 21st century.Some of the topics explored include why are so many people allergic to cats, but so few to hamsters? Do transplants ever reject their new bodies? What is pus? How does your body develop new weapons for new enemies? Why is cancer so hard for our immune system to fight? How does our immune system remember? Why did the 1918 flu pandemic kill mainly young, healthy people? Why did the 2009 swine flu outbreak lead to a spike in sleep disorders? Can we smell someone else's immune system? And does that help us subconsciously decide who we fall in love with?Immune provides an entertaining, intriguing and accessible account of the body's defenses against disease. Drawing on everything from ancient Egyptian medical texts to cutting-edge medical science, the book takes readers on an adventure packed with weird and wonderful facts about their own defense mechanisms, making this both informative and great fun to read.

    Yet, despite the astonishing discoveries of science, we still have only the vaguest idea of how the brain works. In The Idea of the Brain, scientist and historian Matthew Cobb traces how our conception of the brain has evolved over the centuries. Although it might seem to be a story of ever-increasing knowledge of biology, Cobb shows how our ideas about the brain have been shaped by each era's most significant technologies. Today we might think the brain is like a supercomputer. In the past, it has been compared to a telegraph, a telephone exchange, or some kind of hydraulic system. What will we think the brain is like tomorrow, when new technology arises? The result is an essential read for anyone interested in the complex processes that drive science and the forces that have shaped our marvelous brains.

    It will inspire the necessary and difficult conversations we all need to have with loved ones as it illuminates a path to a better way of death.Like so many of us, award-winning writer Katy Butler always assumed her aging parents would experience healthy, active retire­ments before dying peacefully at home. Then her father suffered a stroke that left him incapable of easily finishing a sentence or showering without assistance. Her mother was thrust into full-time caregiving, and Katy became one of the 24 mil­lion Americans who help care for aging parents. In an effort to correct a minor and non–life threatening heart arrhythmia, doctors outfitted her father with a pacemaker. The device kept his heart beating but did nothing to prevent his slide into dementia, incontinence, near-muteness, and misery. After several years, he asked his wife for help, telling her, "I am living too long." Mother and daughter faced a series of wrench­ing moral questions: When does death cease being a curse and become a blessing? Where is the line between saving life and prolonging a dying? When is the right time to say to a doctor, "Let my loved one go"? When doctors refused to disable the pace­maker, sentencing her father to a protracted and agonizing death, Katy set out to understand why. Her quest had barely begun when her mother faced her own illness, rebelled against her doctors, refused open-heart surgery, and instead met death head-on. Knocking on Heaven's Door, a revolution­ary blend of memoir and investigative reporting, is the fruit of the Butler family's journey. With a reporter's skill, a poet's eye, and a daughter's love, Butler explores what happens when our terror of death collides with the tech­nological imperatives of modern medicine. Her provocative thesis is that advanced medicine, in its single-minded pursuit of maximum longevity, often creates more suffering than it prevents. Butler lays bare the tangled web of technology, medicine, and commerce that modern dying has become and chronicles the rise of Slow Medicine - a growing movement that promotes care over cure. Knocking on Heaven's Door is a visionary map through the labyrinth of a broken and morally adrift medical system. It will inspire the necessary and difficult conversations we all need to have with loved ones as it illuminates a path to a better way of death.

    Yet when it comes to fungi, culinary uses are only the tip of the iceberg. Throughout history fungus has been prized for its diverse properties—medicinal, ecological, even recreational—and hasspawned its own quirky subculture dedicated to exploring the weird biology and celebrating the unique role it plays on earth. In Mycophilia, accomplished food writer and cookbook author Eugenia Bone examines the role of fungi as exotic delicacy, curative, poison, and hallucinogen, and ultimately discovers that a greater understanding of fungi is key to facing many challenges of the 21st century.Engrossing, surprising, and packed with up-to-date science and cultural exploration, Mycophilia is part narrative and part primer for foodies, science buffs, environmental advocates, and anyone interested in learning a lot about one of the least understood and most curious organisms in nature.

    Anatomy matters, Alice Domurat Dreger tells us, because the senses we possess, the muscles we control, and the resources we require to keep our bodies alive limit and guide what we experience in any given context. Her deeply thought-provoking and compassionate work exposes the breadth and depth of that context--the extent of the social frame upon which we construct the normal. In doing so, the book calls into question assumptions about anatomy and normality, and transforms our understanding of how we are all intricately and inextricably joined.

    A vice president of the legendary Explorers Club, as well as surgeon, explorer, and masterful storyteller, Dr. Kenneth Kamler has spent years discovering what happens to the human body in extreme environmental conditions. Divided into six sections—jungle, high seas, desert, underwater, high altitude, and outer space—this book uses firsthand testimony and documented accounts to investigate the science of what a body goes through and explains why people survive—and why they sometimes don’t.

    Based on the latest scientific discoveries, Dr Mosley provides a fascinating and detailed understanding of the secrets of this coronavirus, how it spreads, how it infects your body and how your immune system tries to fight back. With access to leading experts, he reports on the battle to find treatments and a safe and effective vaccine (ultimately, the only way to defeat the virus). Armed with the facts about Covid-19 you'll be in a better position to protect yourself and your family as the world begins to reopen. Eating well, sleeping soundly, exercising and managing stress are all vital for keeping your body and immune system in the best possible shape to fight the virus. These are areas where Dr Mosley, creator of the 5:2 diet, is well known for his science-based and practical approach.

    When an epidemic hits, the EIS will be there to crack the case, however mysterious or deadly, saving countless lives in the process. Over the years they have successfully battled polio, cholera, and smallpox, to name a few, and in recent years have turned to the epidemics killing us now--smoking, obesity, and gun violence among them.The successful EIS model has spread internationally: former EIS officers on the staff of the Centers for Disease Control have helped to establish nearly thirty similar programs around the world. EIS veterans have gone on to become leaders in the world of public health in organizations such as the World Health Organization."Inside the Outbreaks" takes readers on a riveting journey through the history of this remarkable organization, following Epidemic Intelligence Service officers on their globetrotting quest to eliminate the most lethal and widespread threats to the world's health.

    Nestled in the Smoky Mountains of eastern Tennessee, the town of Johnson City had always seemed exempt from the anxieties of modern American life. But when the local hospital treated its first AIDS patient, a crisis that had once seemed an urban problem had arrived in the town to stay. Working in Johnson City was Abraham Verghese, a young Indian doctor specializing in infectious diseases. Dr. Verghese became by necessity the local AIDS expert, soon besieged by a shocking number of male and female patients whose stories came to occupy his mind, and even take over his life. Verghese brought a singular perspective to Johnson City: as a doctor unique in his abilities; as an outsider who could talk to people suspicious of local practitioners; above all, as a writer of grace and compassion who saw that what was happening in this conservative community was both a medical and a spiritual emergency."

    Description:- When Breath Becomes Air At the age of thirty-six, on the verge of completing a decade’s training as a neurosurgeon, Paul Kalanithi was diagnosed with inoperable lung cancer. One day he was a doctor treating the dying, the next he was a patient struggling to live. When Breath Becomes Air chronicles Kalanithi’s transformation from a medical student asking what makes a virtuous and meaningful life into a neurosurgeon working in the core of human identity – the brain – and finally into a patient and a new father. Being Mortal: Illness, Medicine and What Matters in the End For most of human history, death was a common, ever-present possibility. It didn't matter whether you were five or fifty - every day was a roll of the dice. But now, as medical advances push the boundaries of survival further each year, we have become increasingly detached from the reality of being mortal. So here is a book about the modern experience of mortality - about what it's like to get old and die, how medicine has changed this and how it hasn't, where our ideas about death have gone wrong. With his trademark mix of perceptiveness and sensitivity, Atul Gawande outlines a story that crosses the globe, as he examines his experiences as a surgeon and those of his patients and family, and learns to accept the limits of what he can do. Where Does it Hurt?: What the Junior Doctor did next He's into his second year of medicine, but this time Max is out of the wards and onto the streets, working for the Phoenix Outreach Project.Fuelled by tea and more enthusiasm than experience, he attempts to locate and treat a wide and colourful range of patients that somehow his first year on the wards didn't prepare him for . . . from Molly the 80-year-old drugs mule and God in a Tesco car park, to middle-class mums addicted to appearances and pain killers in equal measure.

    It was the most extensive reform of America’s health care system since at least the creation of Medicare in 1965, and maybe ever. The ACA was controversial and highly political, and the law faced legal challenges reaching all the way to the Supreme Court; it even precipitated a government shutdown. It was a signature piece of legislation for President Obama’s first term, and also a ball and chain for his second.Ezekiel J. Emanuel, a professor of medical ethics and health policy at the University of Pennsylvania who also served as a special adviser to the White House on health care reform, has written a brilliant diagnostic explanation of why health care in America has become such a divisive social issue, how money and medicine have their own—quite distinct—American story, and why reform has bedeviled presidents of the left and right for more than one hundred years.Emanuel also explains exactly how the ACA reforms are reshaping the health care system now. He forecasts the future, identifying six mega trends in health that will determine the market for health care to 2020 and beyond. His predictions are bold, provocative, and uniquely well-informed. Health care—one of America’s largest employment sectors, with an economy the size of the GDP of France—has never had a more comprehensive or authoritative interpreter.

    Part One presents the general principles of pathophysiology and discusses the influence of the environment and the role of genetics in the development of disease. Part Two, organized by body system, examines normal anatomy and physiology, alterations of function in adults, and alterations of function in children.