She was a poor Southern tobacco farmer who worked the same land as her enslaved ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine. The first “immortal” human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, they’d weigh more than 50 million metric tons—as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions.Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave.Now Rebecca Skloot takes us on an extraordinary journey, from the “colored” ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henrietta’s small, dying hometown of Clover, Virginia — a land of wooden quarters for enslaved people, faith healings, and voodoo — to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells.Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family — past and present — is inextricably connected to the history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of.Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah, who was devastated to learn about her mother’s cells. She was consumed with questions: Had scientists cloned her mother? Did it hurt her when researchers infected her cells with viruses and shot them into space? What happened to her sister, Elsie, who died in a mental institution at the age of fifteen? And if her mother was so important to medicine, why couldn’t her children afford health insurance?Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.

    of photos.

    The disintegration of this group, a process that has been slowly occurring now for more than forty years, has been reported with growing frequency and alarm, but has never before been written about as searingly from the inside. J. D. Vance tells the true story of what a social, regional, and class decline feels like when you were born with it hung around your neck.The Vance family story begins hopefully in postwar America. J. D.’s grandparents were “dirt poor and in love,” and moved north from Kentucky’s Appalachia region to Ohio in the hopes of escaping the dreadful poverty around them. They raised a middle-class family, and eventually one of their grandchildren would graduate from Yale Law School, a conventional marker of success in achieving generational upward mobility. But as the family saga of Hillbilly Elegy plays out, we learn that J.D.'s grandparents, aunt, uncle, sister, and, most of all, his mother struggled profoundly with the demands of their new middle-class life, never fully escaping the legacy of abuse, alcoholism, poverty, and trauma so characteristic of their part of America. With piercing honesty, Vance shows how he himself still carries around the demons of his chaotic family history.A deeply moving memoir, with its share of humor and vividly colorful figures, Hillbilly Elegy is the story of how upward mobility really feels. And it is an urgent and troubling meditation on the loss of the American dream for a large segment of this country.

    In my case, blinking my left eyelid is my only means of communication.’In December 1995, Jean-Dominique Bauby, editor-in-chief of French ‘Elle’ and the father of two young children, suffered a massive stroke and found himself paralysed and speechless, but entirely conscious, trapped by what doctors call ‘locked-in syndrome’. Using his only functioning muscle – his left eyelid – he began dictating this remarkable story, painstakingly spelling it out letter by letter.His book offers a haunting, harrowing look inside the cruel prison of locked-in syndrome, but it is also a triumph of the human spirit.

    Now, acclaimed biographer David Michaelis gives us the first full-length biography of Schulz: at once a creation story, a portrait of a hidden American genius, and a chronicle contrasting the private man with the central role he played in shaping the national imagination. The son of a barber, Schulz was born in Minnesota to modest, working class roots. In 1943, just three days after his mother′s tragic death from cancer, Schulz, a private in the army, shipped out for boot camp and the war in Europe. The sense of shock and separation never left him. And these early experiences would shape his entire life.With Peanuts, Schulz embedded adult ideas in a world of small children to remind the reader that character flaws and childhood wounds are with us always. It was the central truth of his own life, that as the adults we′ve become and as the children we always will be, we can free ourselves, if only we can see the humour in the predicaments of funny-looking kids. Schulz′s Peanuts profoundly influenced the country in the second half of the 20th century. But the strip was anchored in the collective experience and hardships of Schulz′s generation-the generation that survived the Great Depression and liberated Europe and the Pacific and came home to build the post-war world.

    But in this extraordinary autobiography, Shania reveals that she is so much more. She is Eilleen Twain, one of five children born into poverty in rural Canada, where her family often didn't have enough food to send her to school with lunch. She's the teenage girl who helped her mother and young siblings escape to a battered woman's shelter to put an end to the domestic violence in her family home. And she's the courageous twenty-two-year-old who sacrificed to keep her younger siblings together after her parents were tragically killed in a car accident.Shania Twain's life has evolved from a series of pivotal moments, and in unflinching, heartbreaking prose, Shania spares no details as she takes us through the events that have made her who she is. She recounts her difficult childhood, her parents' sudden death and its painful aftermath, her dramatic rise to stardom, her devastating betrayal by a trusted friend, and her joyful marriage to the love of her life. From these moments, she offers profound, moving insights into families, personal tragedies, making sense of one's life, and the process of healing. Shania Twain is a singular, remarkable woman who has faced enormous odds and downfalls, and her extraordinary story will provide wisdom, inspiration, and hope for almost anyone.

    Bad choices were my specialty, and if something honest and decent came along, I would shun it or run the other way.”With striking intimacy and candor, Eric Clapton tells the story of his eventful and inspiring life in this poignant and honest autobiography. More than a rock star, he is an icon, a living embodiment of the history of rock music. Well known for his reserve in a profession marked by self-promotion, flamboyance, and spin, he now chronicles, for the first time, his remarkable personal and professional journeys. Born illegitimate in 1945 and raised by his grandparents, Eric never knew his father and, until the age of nine, believed his actual mother to be his sister. In his early teens his solace was the guitar, and his incredible talent would make him a cult hero in the clubs of Britain and inspire devoted fans to scrawl “Clapton is God” on the walls of London’s Underground. With the formation of Cream, the world's first supergroup, he became a worldwide superstar, but conflicting personalities tore the band apart within two years. His stints in Blind Faith, in Delaney and Bonnie and Friends, and in Derek and the Dominos were also short-lived but yielded some of the most enduring songs in history, including the classic “Layla.” During the late sixties he played as a guest with Jimi Hendrix and Bob Dylan, as well as the Beatles, the Rolling Stones, and longtime friend George Harrison. It was while working with the latter that he fell for George’s wife, Pattie Boyd, a seemingly unrequited love that led him to the depths of despair, self-imposed seclusion, and drug addiction. By the early seventies he had overcome his addiction and released the bestselling album 461 Ocean Boulevard, with its massive hit “I Shot the Sheriff.” He followed that with the platinum album Slowhand, which included “Wonderful Tonight,” the touching love song to Pattie, whom he finally married at the end of 1979. A short time later, however, Eric had replaced heroin with alcohol as his preferred vice, following a pattern of behavior that not only was detrimental to his music but contributed to the eventual breakup of his marriage. In the eighties he would battle and begin his recovery from alcoholism and become a father. But just as his life was coming together, he was struck by a terrible blow: His beloved four-year-old son, Conor, died in a freak accident. At an earlier time Eric might have coped with this tragedy by fleeing into a world of addiction. But now a much stronger man, he took refuge in music, responding with the achingly beautiful “Tears in Heaven.”Clapton is the powerfully written story of a survivor, a man who has achieved the pinnacle of success despite extraordinary demons. It is one of the most compelling memoirs of our time.

    He tells of his childhood in Ontario, where his father instilled in him a love for the written word; his first brush with mortality when he contracted polio at the age of five; struggling to pay rent during his early days with the Squires; traveling the Canadian prairies in Mort, his 1948 Buick hearse; performing in a remote town as a polar bear prowled beneath the floorboards; leaving Canada on a whim in 1966 to pursue his musical dreams in the pot-filled boulevards and communal canyons of Los Angeles; the brief but influential life of Buffalo Springfield, which formed almost immediately after his arrival in California. He recounts their rapid rise to fame and ultimate break-up; going solo and overcoming his fear of singing alone; forming Crazy Horse and writing “Cinnamon Girl,” “Cowgirl in the Sand,” and “Down by the River” in one day while sick with the flu; joining Crosby, Stills & Nash, recording the landmark CSNY album, Déjà vu, and writing the song, “Ohio;” life at his secluded ranch in the redwoods of Northern California and the pot-filled jam sessions there; falling in love with his wife, Pegi, and the birth of his three children; and finally, finding the contemplative paradise of Hawaii. Astoundingly candid, witty, and as uncompromising and true as his music, Waging Heavy Peace is Neil Young’s journey as only he can tell it.

    It has been out of print since at least 1977 and was never published outside the USA.

    After she suffers a brief but serious illness at the age of ninety-one, they resolve to change their relationship by beginning a year-long conversation unlike any they had ever had before. The result is a correspondence of surprising honesty and depth in which they discuss their lives, the things that matter to them, and what they still want to learn about each other.Both a son’s love letter to his mother and an unconventional mom’s life lessons for her grown son, The Rainbow Comes and Goes offers a rare window into their close relationship and fascinating life stories, including their tragedies and triumphs. In these often humorous and moving exchanges, they share their most private thoughts and the hard-earned truths they’ve learned along the way. In their words their distinctive personalities shine through—Anderson’s journalistic outlook on the world is a sharp contrast to his mother’s idealism and unwavering optimism.An appealing memoir with inspirational advice, The Rainbow Comes and Goes is a beautiful and affectionate celebration of the universal bond between a parent and a child, and a thoughtful reflection on life, reminding us of the precious insight that remains to be shared, no matter our age.

    . . . This is an intelligent, thoughtful look into the mind of an artist."--New York Times Book Review Since the release of his first best-selling album Look Sharp in 1979, Joe Jackson has forged a singular career in music through his originality as a composer and his notoriously independent stance toward music-business fashion. He has also been a famously private person, whose lack of interest in his own celebrity has been interpreted by some as aloofness. That reputation is shattered by A Cure for Gravity, Jackson's enormously funny and revealing memoir of growing up musical, from a culturally impoverished childhood in a rough English port town to the Royal Academy of Music, through London's Punk and New Wave scenes, up to the brink of pop stardom. Jackson describes his life as a teenage Beethoven fanatic; his early piano gigs for audiences of glass-throwing skinheads; and his days on the road with long-forgotten club bands. Far from a standard-issue celebrity autobiography, A Cure for Gravity is a smart, passionate book about music, the creative process, and coming of age as an artist.Ralph J. Gleason Music Book Award Finalist

    Just ask anyyone who's ever underestimated him . . . right before he went out and whipped the WWE universe into a frenzy.This is Bryan's behind-the-scenes story told for the first time ever by the "YES!" Man himself---from his beginnings as a child wanting to wrestle to his ten years circling the globe on the independent circuit and his remarkable climb to the upper ranks of WWE.As the biggest week of his life unfolds, Aberdeen, Washington's bearded son reflects in full detail on his incredible path to the top and gives his take on the events that have shaped him. With his Bryan-ized blend of modesty and surprising candor, Daniel pulls no punches (or martial arts kicks) as he reveals his true thoughts on his evolution as a performer, his various roles in WWE versus the independent years, life on the road, at home, and much more.And of course, get the untold story surrounding the "YES!" chant that evolved to full-fledged movement, skyrocketing his career. This book chronicles all the hard work, values, influences, unique life choices, and more, leading to his watershed week at WrestleMania 30. You won't want to miss it. Yes! We're sure about this.

    After a rejection from an elite New York conservatoire—a rejection she always believed stemmed from the color of her skin—she began performing jazz, blues, and classical songs in a bar to fund her music studies. In 1958 her rendition of the Gershwin standard “I Loves You Porgy” became a Top 40 hit, and her subsequent debut album Little Girl Blue launched what would become an extensive singing and songwriting career. Drawing on a wealth of original interviews with Simone’s closest associates, this extraordinary biography follows her sparkling career as well as her passionate belief in racial equality that eventually led her to undergo self-imposed exile from America in 1970. Featuring rare photographs and a review of Simone’s more than 40 albums and numerous hits, this is an extensive look at the complex and extremely talented diva.

    Before Carrie Brownstein codeveloped and starred in the wildly popular TV comedy Portlandia, she was already an icon to young women for her role as a musician in the feminist punk band Sleater-Kinney. The band was a key part of the early riot- grrrl and indie rock scenes in the Pacific Northwest, known for their prodigious guitar shredding and their leftist lyrics against war, traditionalism, and gender roles.Hunger Makes Me a Modern Girl is the deeply personal and revealing narrative of Brownstein's life in music, from ardent fan to pioneering female guitarist to comedic performer and luminary in the independent rock world. Though Brownstein struggled against the music industry's sexist double standards, by 2006 she was the only woman to earn a spot on Rolling Stone readers' list of the "25 Most Underrated Guitarists of All-Time." This book intimately captures what it feels like to be a young woman in a rock-and-roll band, from her days at the dawn of the underground feminist punk-rock movement that would define music and pop culture in the 1990s through today.

    But the writer possessed another side, one which is delightfully exposed in this hilariously charming memoir of her family's life in rural Vermont. Fans of Please Don't Eat the Daisies, Cheaper by the Dozen, and anything Erma Bombeck ever wrote will find much to recognize in Shirley Jackson's home and neighborhood: children who won't behave, cars that won't start, furnaces that break down, a pugnacious corner bully, household help that never stays, and a patient, capable husband who remains lovingly oblivious to the many thousands of things mothers and wives accomplish every single day."Our house," writes Jackson, "is old, noisy, and full. When we moved into it we had two children and about five thousand books; I expect that when we finally overflow and move out again we will have perhaps twenty children and easily half a million books." Jackson's literary talents are in evidence everywhere, as is her trenchant, unsentimental wit. Yet there is no mistaking the happiness and love in these pages, which are crowded with the raucous voices of an extraordinary family living a wonderfully ordinary life.