Many books on the plague rely on statistics to tell the story: how many people died; how farm output and trade declined. But statistics can’t convey what it was like to sit in Siena or Avignon and hear that a thousand people a day are dying two towns away. Or to have to chose between your own life and your duty to a mortally ill child or spouse. Or to live in a society where the bonds of blood and sentiment and law have lost all meaning, where anyone can murder or rape or plunder anyone else without fear of consequence.In The Great Mortality, author John Kelly lends an air of immediacy and intimacy to his telling of the journey of the plague as it traveled from the steppes of Russia, across Europe, and into England, killing 75 million people—one third of the known population—before it vanished.

    Obsessive and inspired efforts by scientists to solve mysteries and save lives. From The Hot Zone to The Demon in the Freezer and beyond, Richard Preston’s bestselling works have mesmerized readers everywhere by showing them strange worlds of nature they never dreamed of.Panic in Level 4 is a grand tour through the eerie and unforgettable universe of Richard Preston, filled with incredible characters and mysteries that refuse to leave one’s mind. Here are dramatic true stories from this acclaimed and award-winning author, including:• The phenomenon of “self-cannibals,” who suffer from a rare genetic condition caused by one wrong letter in their DNA that forces them to compulsively chew their own flesh–and why everyone may have a touch of this disease.• The search for the unknown host of Ebola virus, an organism hidden somewhere in African rain forests, where the disease finds its way into the human species, causing outbreaks of unparalleled horror.• The brilliant Russian brothers–“one mathematician divided between two bodies”–who built a supercomputer in their apartment from mail-order parts in an attempt to find hidden order in the number pi (π).In fascinating, intimate, and exhilarating detail, Richard Preston portrays the frightening forces and constructive discoveries that are currently roiling and reordering our world, once again proving himself a master of the nonfiction narrative and, as noted in The Washington Post, “a science writer with an uncommon gift for turning complex biology into riveting page-turners.”From the Hardcover edition.

    In three successive waves, from 1918 to 1919, influenza killed more than 50 million people. German soldiers termed it Blitzkatarrh, British soldiers referred to it as Flanders Grippe, but world-wide, the pandemic gained the notorious title of “Spanish Flu." Nowhere on earth escaped: the United States recorded 550,000 deaths (five times its total military fatalities in the war), while European deaths totaled more than two million.Amid the war, some governments suppressed news of the outbreak. Even as entire battalions were decimated, with both the Allies and the Germans suffering massive casualties, the details of many servicemen’s deaths were hidden to protect public morale. Meanwhile, civilian families were being struck down in their homes. Philadelphia ran out of gravediggers and coffins, and mass burial trenches had to be excavated with steam shovels. Spanish flu conjured up the specter of the Black Death of 1348 and the great plague of 1665, while the medical profession, shattered after five terrible years of conflict, lacked the resources to contain and defeat this new enemy. Through primary and archival sources, historian Catharine Arnold gives readers the first truly global account of this terrible epidemic.

    Practical Algebra is an easy andfun-to-use workout program that quickly puts you in command of allthe basic concepts and tools of algebra. With the aid of practical, real-life examples and applications, you'll learn: * The basic approach and application of algebra to problemsolving * The number system (in a much broader way than you have known itfrom arithmetic) * Monomials and polynomials; factoring algebraic expressions; howto handle algebraic fractions; exponents, roots, and radicals;linear and fractional equations * Functions and graphs; quadratic equations; inequalities; ratio, proportion, and variation; how to solve word problems, andmore Authors Peter Selby and Steve Slavin emphasize practical algebrathroughout by providing you with techniques for solving problems ina wide range of disciplines--from engineering, biology, chemistry, and the physical sciences, to psychology and even sociology andbusiness administration. Step by step, Practical Algebra shows youhow to solve algebraic problems in each of these areas, then allowsyou to tackle similar problems on your own, at your own pace.Self-tests are provided at the end of each chapter so you canmeasure your mastery.

    In the highly litigated area of Special Education, it is imperative that professionals in the field understand the legal requirements of providing a free appropriate public education to students with disabilities. This text presents the necessary information for educators to understand the history and development of special education laws and the requirements of these laws. It provides the reader with the necessary skills to locate pertinent information in law libraries, on the Internet, and other sources to keep abreast of the constant changes and developments in the field. The second edition of The Law and Special Education, one of the top special education law books in the field, includes new information on the Individuals with Disabilities Education Act of 2004 and the No Child Left Behind Act of 2001. It has been updated with the latest information on the statutes, regulations, policy guidance, and cases on special education law.

    It presents positioning and projection information in an easy-to-read, bulleted format on one side of the page spread, with corresponding positioning photos, radiographic images and anatomical drawings on the other side. Expert content covers pathology, geriatric and pediatric patient populations, survey information, and 100 new positioning photographs for the latest in radiographic positioning. The 6th edition contains a new chapter on digital imaging, and digital imaging information is incorporated where appropriate throughout the book. New photographs and redrawn illustrations create a consistent, visual appearance throughout the book.- Characterized by a clear, easy-to-follow organization that features one projection per page. Positioning and projection information is presented in an easy-to-read bulleted format on the left side of the page, and positioning photos, radiographic images and anatomical drawings are aligned on the right. This show and tell style helps students visualize anatomy and understand positioning.- Includes about 200 of the most commonly requested projections. Competency in performing these projections is necessary for all entry-level practitioners. By contrast, Merrill's Atlas includes over 400 projections and much more information on advanced imaging.- Critique Radiographs provide the basis of classroom or lab discussion. The WB/LM contains questions specific to these radiographs.- Pathologic Indications in appropriate chapters - Introducing pathology with positioning helps students understand the whole patient and improves their ability to produce radiographs that make diagnosis easy for the physician.- Pediatric Applications in appropriate chapters prepare technologists to deal competently with the special needs of their pediatric patients.- Geriatric Applications in appropriate chapters - Important information for technologists to understand the varying needs of their patient base.- Alternative Modalities or procedures inform students of which projections can better demonstrate certain anatomical parts or pathology, or which may be necessary if patient is unable to cooperate fully.- Radiographic Criteria on positioning pages help students develop a routine for evaluating radiographic quality.- Pathology Demonstrated provides students with a larger frame of reference, and therefore a greater understanding, of each projectionA new chapter on digital imaging discusses basic principles, applications, and image quality - digital imaging information essential for making appropriate positioning adjustments - to ensure readers are prepared to encounter new technology in clinical practice.Content updates include a totally new section on surgical radiography, new sections in all chapters on digital imaging considerations, an expanded section on bone densitometry, and a new introduction to positron emission tomography (PET).Updated and revised chapters cover angiography and interventional procedures, and computed tomography.More than 150 new positioning photos, in addition to many updated images, complement the new material.

    Yet despite a century of medical progress, viral and bacterial disasters continue to take us by surprise, inciting panic and dominating news cycles. From the Spanish flu to the 1924 outbreak of pneumonic plague in Los Angeles to the 1930 “parrot fever” pandemic, through the more recent SARS, Ebola, and Zika epidemics, the last one hundred years have been marked by a succession of unanticipated pandemic alarms.In The Pandemic Century, a lively account of scares both infamous and less known, Mark Honigsbaum combines reportage with the history of science and medical sociology to artfully reconstruct epidemiological mysteries and the ecology of infectious diseases. We meet dedicated disease detectives, obstructive or incompetent public health officials, and brilliant scientists often blinded by their own knowledge of bacteria and viruses. We also see how fear of disease often exacerbates racial, religious, and ethnic tensions—even though, as the epidemiologists Malik Peiris and Yi Guan write, “‘nature’ remains the greatest bioterrorist threat of all.”Like man-eating sharks, predatory pathogens are always present in nature, waiting to strike; when one is seemingly vanquished, others appear in its place. These pandemics remind us of the limits of scientific knowledge, as well as the role that human behavior and technologies play in the emergence and spread of microbial diseases.

    It could be an oddball researcher’s genius insight, a catalyzing moment in geopolitical history, a new breakthrough technology, or an unexpected but welcome side effect discovered during clinical trials. Piece together these stories, as Thomas Hager does in this remarkable, century-spanning history, and you can trace the evolution of our culture and the practice of medicine.  ​Beginning with opium, the “joy plant,” which has been used for 10,000 years, Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.

     Douglas Montgomery arms readers with the most effective approach for learning how to design, conduct, and analyze experiments that optimize performance in products and processes. He shows how to use statistically designed experiments to obtain information for characterization and optimization of systems, improve manufacturing processes, and design and develop new processes and products. You will also learn how to evaluate material alternatives in product design, improve the field performance, reliability, and manufacturing aspects of products, and conduct experiments effectively and efficiently. Discover how to improve the quality and efficiency of working systems with this highly-acclaimed book. This 6th Edition: Places a strong focus on the use of the computer, providing output from two software products: Minitab and DesignExpert. Presents timely, new examples as well as expanded coverage on adding runs to a fractional factorial to de-alias effects. Includes detailed discussions on how computers are currently used in the analysis and design of experiments. Offers new material on a number of important topics, including follow-up experimentation and split-plot design. Focuses even more sharply on factorial and fractional factorial design.

    But humans are not machines. When we are ill, we experience our illness: we become scared, distressed, tired, weary. Our illnesses are not just biological conditions, but human ones. It was Arthur Kleinman, a Harvard psychiatrist and anthropologist, who saw this truth when most of his fellow doctors did not. Based on decades of clinical experience studying and treating chronic illness, The Illness Narratives makes a case for interpreting the illness experience of patients as a core feature of doctoring.Before Being Mortal, there was The Illness Narratives. It remains today a prescient and passionate case for bridging the gap between patient and practitioner.

    Essentially, you make an initial guess, and then get more data to improve it. Bayes Theorem, or Bayes Rule, has a ton of real world applications, from estimating your risk of a heart attack to making recommendations on Netflix But It Isn't That Complicated This book is a short introduction to Bayes Theorem. It is only 15 pages long, and is intended to show you how Bayes Theorem works as quickly as possible. The examples are intentionally kept simple to focus solely on Bayes Theorem without requiring that the reader know complicated probability distributions. If you want to learn the basics of Bayes Theorem as quickly as possible, with some easy to duplicate examples, this is a good book for you.

    She was repeatedly hospitalized in excruciating pain, but the doctors insisted it was a urinary tract infection and sent her home with antibiotics. Unable to get out of bed, much less attend class, Norman dropped out of college and embarked on what would become a years-long journey to discover what was wrong with her. It wasn't until she took matters into her own hands--securing a job in a hospital and educating herself over lunchtime reading in the medical library--that she found an accurate diagnosis of endometriosis.In Ask Me About My Uterus, Norman describes what it was like to have her pain dismissed, to be told it was all in her head, only to be taken seriously when she was accompanied by a boyfriend who confirmed that her sexual performance was, indeed, compromised. Putting her own trials into a broader historical, sociocultural, and political context, Norman shows that women's bodies have long been the battleground of a never-ending war for power, control, medical knowledge, and truth. It's time to refute the belief that being a woman is a preexisting condition.

    This practical text reviews basic microbiology and how to approach the pharmacotherapy of a patient with a presumed infection. It also contains concise Drug Class Reviews with an explanation of the characteristics of various classes of antibacterial drugs and antifungal drugs. Antibiotics Simplified, Third Edition simplifies learning infectious disease pharmacotherapy and condenses the many facts that are taught about antibiotics into one quick reference guide. This guide will help students learn the characteristics of antibiotics and why an antibiotic is useful for an indication. With an understanding of the characteristics of the antibiotics, students will be able to make a logical choice to treat an infection more easily. With helpful figures and flow charts, Drug Class Reviews, a Spectra of Activity chart, and an index for reference, this is an ideal handbook for students as well as practicing pharmacists, physicians, and other clinicians!

    Ballet dancers and rock musicians, professors and thieves-"anyone who had fallen, or, often, leapt, onto hard times" and needed extended medical care-ended up here. So did Victoria Sweet, who came for two months and stayed for twenty years. Laguna Honda, lower tech but human paced, gave Sweet the opportunity to practice a kind of attentive medicine that has almost vanished. Gradually, the place transformed the way she understood her work. Alongside the modern view of the body as a machine to be fixed, her extraordinary patients evoked an older idea, of the body as a garden to be tended. God's Hotel tells their story and the story of the hospital itself, which, as efficiency experts, politicians, and architects descended, determined to turn it into a modern "health care facility," revealed its own surprising truths about the essence, cost, and value of caring for body and soul.

    The Human Genome Project finished sequencing human DNA. It seemed it was only a matter of time until we had all the answers to the secrets of life on this planet. The cutting-edge of biology, however, is telling us that we still don't even know all of the questions. How is it that, despite each cell in your body carrying exactly the same DNA, you don't have teeth growing out of your eyeballs or toenails on your liver? How is it that identical twins share exactly the same DNA and yet can exhibit dramatic differences in the way that they live and grow? It turns out that cells read the genetic code in DNA more like a script to be interpreted than a mould that replicates the same result each time. This is epigenetics and it's the fastest-moving field in biology today. The Epigenetics Revolution traces the thrilling path this discipline has taken over the last twenty years. Biologist Nessa Carey deftly explains such diverse phenomena as how queen bees and ants control their colonies, why tortoiseshell cats are always female, why some plants need a period of cold before they can flower, why we age, develop disease and become addicted to drugs, and much more. Most excitingly, Carey reveals the amazing possibilities for humankind that epigenetics offers for us all - and in the surprisingly near future.