The Code Breaker: Jennifer Doudna, Gene Editing, and the Future of the Human Race


Walter Isaacson - 2021
    As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned ​a curiosity ​of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020.

Futureproof: 9 Rules for Humans in the Age of Automation


Kevin Roose - 2021
    After decades of sci-fi fantasies and hype, artificial intelligence has leapt out of research labs and Silicon Valley engineering departments and into the center of our lives. Algorithms shape everything around us, from the news we see to the products we buy and the relationships we form. And while the debate over whether or not automation will destroy jobs rages on, a much more important question is being ignored:What does it mean to be a human in a world that is increasingly built by and for machines?In Futureproof: 9 Rules for Humans in the Age of Automation, New York Times technology columnist Kevin Roose lays out a hopeful, pragmatic vision of how people can succeed in the machine age by making themselves irreplaceably human. He shares the secrets of people and organizations that have survived technological change, and explains how we can protect our own futures, with lessons like- Do work that is surprising, social, and scarce (the types of work machines can't do). - Demote your phone. - Work near other people. - Treat A.I. like an army of chimpanzees. - Add more friction to your life.Roose rejects the conventional wisdom that in order to compete with machines, we have to become more like them--hyper-efficient, data-driven, code-writing workhorses. Instead, he says, we should let machines be machines, and focus on doing the kinds of creative, inspiring, and meaningful things only humans can do.

Smarter Than You Think: How Technology is Changing Our Minds for the Better


Clive Thompson - 2013
    But is it for the better? Amid a chorus of doomsayers, Clive Thompson delivers a resounding "yes." The Internet age has produced a radical new style of human intelligence, worthy of both celebration and analysis. We learn more and retain it longer, write and think with global audiences, and even gain an ESP-like awareness of the world around us. Modern technology is making us smarter, better connected, and often deeper—both as individuals and as a society. In Smarter Than You Think Thompson shows that every technological innovation—from the written word to the printing press to the telegraph—has provoked the very same anxieties that plague us today. We panic that life will never be the same, that our attentions are eroding, that culture is being trivialized. But as in the past, we adapt—learning to use the new and retaining what’s good of the old. Thompson introduces us to a cast of extraordinary characters who augment their minds in inventive ways. There's the seventy-six-year old millionaire who digitally records his every waking moment—giving him instant recall of the events and ideas of his life, even going back decades. There's a group of courageous Chinese students who mounted an online movement that shut down a $1.6 billion toxic copper plant. There are experts and there are amateurs, including a global set of gamers who took a puzzle that had baffled HIV scientists for a decade—and solved it collaboratively in only one month. Smarter Than You Think isn't just about pioneers. It's about everyday users of technology and how our digital tools—from Google to Twitter to Facebook and smartphones—are giving us new ways to learn, talk, and share our ideas. Thompson harnesses the latest discoveries in social science to explore how digital technology taps into our long-standing habits of mind—pushing them in powerful new directions. Our thinking will continue to evolve as newer tools enter our lives. Smarter Than You Think embraces and extols this transformation, presenting an exciting vision of the present and the future.

Dragons of Eden: Speculations on the Evolution of Human Intelligence


Carl Sagan - 1977
    Dr Carl Sagan takes us on a great reading adventure, offering his vivid and startling insights into the brains of humans & beasts, the origin of human intelligence, the function of our most haunting legends and their amazing links to recent discoveries.

The Ascent of Man


Jacob Bronowski - 1973
    Bronowski's exciting, illustrated investigation offers a perspective not just on science, but on civilization itself. Lower than the angelsForewordThe harvest of the seasons The grain in the stoneThe hidden structure The music of the spheresThe starry messanger The majestic clockworkThe drive for power The ladder of creation World within world Knowledge or certainty Generation upon generationThe long childhoodBibliographyIndex

Quantum: Einstein, Bohr and the Great Debate About the Nature of Reality


Manjit Kumar - 2007
    And yet for many years it was equally baffling for scientists themselves. Manjit Kumar gives a dramatic and superbly-written history of this fundamental scientific revolution, and the divisive debate at its heart.For 60 years most physicists believed that quantum theory denied the very existence of reality itself. Yet Kumar shows how the golden age of physics ignited the greatest intellectual debate of the twentieth century.Quantum sets the science in the context of the great upheavals of the modern age. In 1925 the quantum pioneers nearly all hailed from upper-middle-class academic families; most were German; and their average age was 24. But it was their irrational, romantic spirit, formed in reaction to the mechanised slaughter of the First World War that inspired their will to test science to its limits.The essential read for anyone fascinated by this complex and thrilling story and by the band of young men at its heart.

Napoleon's Buttons: How 17 Molecules Changed History


Penny Le Couteur - 1991
    When temperatures drop below 56°F, tin crumbles into powder. Were the soldiers of the Grande Armée acutee fatally weakened by cold because the buttons of their uniforms fell apart? How different our world might be if tin did not disintegrate at low temperatures and the French had continued their eastward expansion! This fascinating book tells the stories of seventeen molecules that, like the tin of those buttons, greatly influenced the course of history. These molecules provided the impetus for early exploration and made possible the ensuing voyages of discovery. They resulted in grand feats of engineering and spurred advances in medicine; lie behind changes in gender roles, in law, and in the environment; and have determined what we today eat, drink, and wear. Showing how a change as small as the position of an atom can lead to enormous differences in the properties of a substance, the authors reveal the astonishing chemical connections among seemingly unrelated events. Napoleon's Buttons offers a novel way to understand how our contemporary world works and how our civilization has been shaped over time.

The Gene: An Intimate History


Siddhartha Mukherjee - 2016
    It intersects with Darwin’s theory of evolution, and collides with the horrors of Nazi eugenics in the 1940s. The gene transforms post-war biology. It reorganizes our understanding of sexuality, temperament, choice and free will. This is a story driven by human ingenuity and obsessive minds – from Charles Darwin and Gregor Mendel to Francis Crick, James Watson and Rosalind Franklin, and the thousands of scientists still working to understand the code of codes.This is an epic, moving history of a scientific idea coming to life, by the author of The Emperor of All Maladies. But woven through The Gene, like a red line, is also an intimate history – the story of Mukherjee’s own family and its recurring pattern of mental illness, reminding us that genetics is vitally relevant to everyday lives. These concerns reverberate even more urgently today as we learn to “read” and “write” the human genome – unleashing the potential to change the fates and identities of our children.Majestic in its ambition, and unflinching in its honesty, The Gene gives us a definitive account of the fundamental unit of heredity – and a vision of both humanity’s past and future.

The Billion-Dollar Molecule: The Quest for the Perfect Drug


Barry Werth - 1994
    You will be hooked from start to finish, as you go from the labs, where obsessive, fiercely competitive scientists struggle for a breakthrough, to Wall Street, where the wheeling and dealing takes on a life of its own, as Boger courts investors and finally decides to take Vertex public. Here is a fascinating no-holds-barred account of the business of science, which includes an updated epilogue about the most recent developments in the quest for a drug to cure AIDS.

Complexity: The Emerging Science at the Edge of Order and Chaos


M. Mitchell Waldrop - 1992
    The science of complexity studies how single elements, such as a species or a stock, spontaneously organize into complicated structures like ecosystems and economies; stars become galaxies, and snowflakes avalanches almost as if these systems were obeying a hidden yearning for order. Drawing from diverse fields, scientific luminaries such as Nobel Laureates Murray Gell-Mann and Kenneth Arrow are studying complexity at a think tank called The Santa Fe Institute. The revolutionary new discoveries researchers have made there could change the face of every science from biology to cosmology to economics. M. Mitchell Waldrop's groundbreaking bestseller takes readers into the hearts and minds of these scientists to tell the story behind this scientific revolution as it unfolds.

Future Crimes


Marc Goodman - 2015
    Hackers can activate baby monitors to spy on families, thieves are analyzing social media posts to plot home invasions, and stalkers are exploiting the GPS on smart phones to track their victims’ every move. We all know today’s criminals can steal identities, drain online bank accounts, and wipe out computer servers, but that’s just the beginning. To date, no computer has been created that could not be hacked—a sobering fact given our radical dependence on these machines for everything from our nation’s power grid to air traffic control to financial services.      Yet, as ubiquitous as technology seems today, just over the horizon is a tidal wave of scientific progress that will leave our heads spinning. If today’s Internet is the size of a golf ball, tomorrow’s will be the size of the sun. Welcome to the Internet of Things, a living, breathing, global information grid where every physical object will be online. But with greater connections come greater risks. Implantable medical devices such as pacemakers can be hacked to deliver a lethal jolt of electricity and a car’s brakes can be disabled at high speed from miles away. Meanwhile, 3-D printers can produce AK-47s, bioterrorists can download the recipe for Spanish flu, and cartels are using fleets of drones to ferry drugs across borders.     With explosive insights based upon a career in law enforcement and counterterrorism, Marc Goodman takes readers on a vivid journey through the darkest recesses of the Internet. Reading like science fiction, but based in science fact, Future Crimes explores how bad actors are primed to hijack the technologies of tomorrow, including robotics, synthetic biology, nanotechnology, virtual reality, and artificial intelligence. These fields hold the power to create a world of unprecedented abundance and prosperity. But the technological bedrock upon which we are building our common future is deeply unstable and, like a house of cards, can come crashing down at any moment.     Future Crimes provides a mind-blowing glimpse into the dark side of technological innovation and the unintended consequences of our connected world. Goodman offers a way out with clear steps we must take to survive the progress unfolding before us. Provocative, thrilling, and ultimately empowering, Future Crimes will serve as an urgent call to action that shows how we can take back control over our own devices and harness technology’s tremendous power for the betterment of humanity—before it’s too late.From the Hardcover edition.

The Master Algorithm: How the Quest for the Ultimate Learning Machine Will Remake Our World


Pedro Domingos - 2015
    In The Master Algorithm, Pedro Domingos lifts the veil to give us a peek inside the learning machines that power Google, Amazon, and your smartphone. He assembles a blueprint for the future universal learner--the Master Algorithm--and discusses what it will mean for business, science, and society. If data-ism is today's philosophy, this book is its bible.

Endless Forms Most Beautiful: The New Science of Evo Devo and the Making of the Animal Kingdom


Sean B. Carroll - 2005
    Evo Devo Evolutionary Developmental Biology is the new science that has finally cracked open the box. Within the pages of his rich and riveting book, Sean B. Carroll explains how we are discovering that complex life is ironically much simpler than anyone ever expected.

Connections


James Burke - 1978
    He untangles the pattern of interconnecting events, the accidents of time, circumstance, and place that gave rise to major inventions of the world. Says Burke, "My purpose is to acquaint the reader with some of the forces that have caused change in the past, looking in particular at eight innovations - the computer, the production line, telecommunications, the airplane, the atomic bomb, plastics, the guided rocket, and television - which may be most influential in structuring our own futures.... Each one of these is part of a family of similar devices, and is the result of a sequence of closely connected events extending from the ancient world until the present day. Each has enormous potential for humankind's benefit - or destruction."

The Double Helix


James D. Watson - 1968
    At the time, Watson was only 24, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science's greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions & bitter rivalries. With humility unspoiled by false modesty, Watson relates his & Crick's desperate efforts to beat Linus Pauling to the Holy Grail of life sciences, the identification of the basic building block of life. Never has a scientist been so truthful in capturing in words the flavor of his work.