Indeed, these tiny structures inside our cells are important beyond imagining. Without mitochondria, we would have no cell suicide, no sculpting of embryonic shape, no sexes, no menopause, no aging.In this fascinating and thought-provoking book, Nick Lane brings together the latest research in this exciting field to show how our growing insight into mitochondria has shed light on how complex life evolved, why sex arose (why don't we just bud?), and why we age and die. These findings are of fundamental importance, both in understanding life on Earth, but also in controlling our own illnesses, and delaying our degeneration and death. Readers learn that two billion years ago, mitochondria were probably bacteria living independent lives and that their capture within larger cells was a turning point in the evolution of life, enabling the development of complex organisms. Lane describes how mitochondria have their own DNA and that its genes mutate much faster than those in the nucleus. This high mutation rate lies behind our aging and certain congenital diseases. The latest research suggests that mitochondria play a key role in degenerative diseases such as cancer. We also discover that mitochondrial DNA is passed down almost exclusively via the female line. That's why it has been used by some researchers to trace human ancestry daughter-to-mother, to "Mitochondrial Eve," giving us vital information about our evolutionary history.Written by Nick Lane, a rising star in popular science, Power, Sex, Suicide is the first book for general readers on the nature and function of these tiny, yet fascinating structures.

    Taut, brooding, and densely atmospheric, these stories show us the ways in which murder can arise out of boredom, perversity can result from adolescent curiosity, and sheer evil might be the solution to unbearable loneliness. These tales are as horrifying as anything written by Clive Barker or Stephen King, but they are crafted with a lyricism and intensity that compel us to confront our secret kinship with the horrifying.

    He's a Vietnam veteran, a jazz pianist, a college professor, and a prognosticator of the apocalypse (and other things Earth-shattering). But that's neither here no there. Because at Tarkington College—where he teaches—the excrement is about to hit the air-conditioning. And its all Eugene's fault.

    As Professor of Anatomy and Forensic Anthropology, she focuses on mortal remains in her lab, at burial sites, at scenes of violence, murder and criminal dismemberment, and when investigating mass fatalities due to war, accident or natural disaster. In All that Remains she reveals the many faces of death she has come to know, using key cases to explore how forensic science has developed, and what her work has taught her. Do we expect a book about death to be sad? Macabre? Sue’s book is neither. There is tragedy, but there is also humour in stories as gripping as the best crime novel. Our own death will remain a great unknown. But as an expert witness from the final frontier, Sue Black is the wisest, most reassuring, most compelling of guides.

    She knows that her real name is Purity, that she's saddled with $130,000 in student debt, that she's squatting with anarchists in Oakland, and that her relationship with her mother - her only family - is hazardous. But she doesn't have a clue who her father is, why her mother chose to live as a recluse with an invented name, or how she'll ever have a normal life. Enter the Germans. A glancing encounter with a German peace activist leads Pip to an internship in South America with The Sunlight Project, an organization that traffics in all the secrets of the world--including, Pip hopes, the secret of her origins. TSP is the brainchild of Andreas Wolf, a charismatic provocateur who rose to fame in the chaos following the fall of the Berlin Wall. Now on the lam in Bolivia, Andreas is drawn to Pip for reasons she doesn't understand, and the intensity of her response to him upends her conventional ideas of right and wrong. Purity is a grand story of youthful idealism, extreme fidelity, and murder. The author of The Corrections and Freedom has imagined a world of vividly original characters - Californians and East Germans, good parents and bad parents, journalists and leakers - and he follows their intertwining paths through landscapes as contemporary as the omnipresent Internet and as ancient as the war between the sexes. Purity is the most daring and penetrating book yet by one of the major writers of our time.

    It is the history of who you are and how you came to be. It is unique to you, as it is to each of the 100 billion modern humans who have ever drawn breath. But it is also our collective story, because in every one of our genomes we each carry the history of our species births, deaths, disease, war, famine, migration, and a lot of sex. Since scientists first read the human genome in 2001, it has been subject to all sorts of claims, counterclaims, and myths. In fact, as Adam Rutherford explains, our genomes should be read not as instruction manuals, but as epic poems. DNA determines far less than we have been led to believe about us as individuals, but vastly more about us as a species. In this captivating journey through the expanding landscape of genetics, Adam Rutherford reveals what our genes now tell us about history, and what history tells us about our genes. From Neanderthals to murder, from redheads to race, dead kings to plague, evolution to epigenetics, this is a demystifying and illuminating new portrait of who we are and how we came to be."

    One night in winter, Peter Lake, orphan and master-mechanic, attempts to rob a fortress-like mansion on the Upper West Side.Though he thinks the house is empty, the daughter of the house is home. Thus begins the love between Peter Lake, a middle-aged Irish burglar, and Beverly Penn, a young girl, who is dying.Peter Lake, a simple, uneducated man, because of a love that, at first he does not fully understand, is driven to stop time and bring back the dead. His great struggle, in a city ever alight with its own energy and besieged by unprecedented winters, is one of the most beautiful and extraordinary stories of American literature.

    These are today's sins of science—as deplorable as mistaken past ideas about advocating racial purity or using lobotomies as a cure for mental illness. These unwitting errors add up to seven lessons both cautionary and profound, narrated by renowned author and speaker Paul A. Offit. Offit uses these lessons to investigate how we can separate good science from bad, using some of today's most controversial creations—e-cigarettes, GMOs, drug treatments for ADHD—as case studies. For every "Aha!" moment that should have been an "Oh no," this book is an engrossing account of how science has been misused disastrously—and how we can learn to use its power for good.

    A teenage girl—her father long since disappeared, her mother unwilling to have her in the house—is pregnant, alone herself, with nowhere to go. And out in the country, two brothers, elderly bachelors, work the family homestead, the only world they've ever known.From these unsettled lives emerges a vision of life, and of the town and landscape that bind them together—their fates somehow overcoming the powerful circumstances of place and station, their confusion, curiosity, dignity and humor intact and resonant. As the milieu widens to embrace fully four generations, Kent Haruf displays an emotional and aesthetic authority to rival the past masters of a classic American tradition.Utterly true to the rhythms and patterns of life, Plainsong is a novel to care about, believe in, and learn from.

    Librarian note: an alternate cover for this edition can be found here.Michel Foucault examines the archeology of madness in the West from 1500 to 1800 – from the late Middle Ages, when insanity was still considered part of everyday life and fools and lunatics walked the streets freely, to the time when such people began to be considered a threat, asylums were first built, and walls were erected between the “insane” and the rest of humanity.

    We own radiation-emitting phones, regularly get diagnostic x-rays, such as mammograms, and submit to full-body security scans at airports. We worry and debate about the proliferation of nuclear weapons and the safety of nuclear power plants. But how much do we really know about radiation? And what are its actual dangers? An accessible blend of narrative history and science, Strange Glow describes mankind's extraordinary, thorny relationship with radiation, including the hard-won lessons of how radiation helps and harms our health. Timothy Jorgensen explores how our knowledge of and experiences with radiation in the last century can lead us to smarter personal decisions about radiation exposures today.Jorgensen introduces key figures in the story of radiation--from Wilhelm Roentgen, the discoverer of x-rays, and pioneering radioactivity researchers Marie and Pierre Curie, to Thomas Edison and the victims of the recent Fukushima Daiichi nuclear power plant accident. Tracing the most important events in the evolution of radiation, Jorgensen explains exactly what radiation is, how it produces certain health consequences, and how we can protect ourselves from harm. He also considers a range of practical scenarios such as the risks of radon in our basements, radiation levels in the fish we eat, questions about cell-phone use, and radiation's link to cancer. Jorgensen empowers us to make informed choices while offering a clearer understanding of broader societal issues.Investigating radiation's benefits and risks, Strange Glow takes a remarkable look at how, for better or worse, radiation has transformed our society.

    Patrick Lewis arrives in Toronto in the 1920s and earns his living searching for a vanished millionaire and tunneling beneath Lake Ontario. In the course of his adventures, Patrick's life intersects with those of characters who reappear in Ondaatje's Booker Prize-winning The English Patient. 256 pp.

    Hailed by the Los Angeles Times as the “newest name after Wells, Verne, Huxley, and Orwell,” Callenbach offers a visionary blueprint for the survival of our planet . . . and our future. Ecotopia was founded when northern California, Oregon, and Washington seceded from the Union to create a “stable-state” ecosystem: the perfect balance between human beings and the environment. Now, twenty years later, this isolated, mysterious nation is welcoming its first officially sanctioned American visitor: New York Times-Post reporter Will Weston.Skeptical yet curious about this green new world, Weston is determined to report his findings objectively. But from the start, he’s alternately impressed and unsettled by the laws governing Ecotopia’s earth-friendly agenda: energy-efficient “mini-cities” to eliminate urban sprawl, zero-tolerance pollution control, tree worship, ritual war games, and a woman-dominated government that has instituted such peaceful revolutions as the twenty-hour workweek and employee ownership of farms and businesses. His old beliefs challenged, his cynicism replaced by hope, Weston meets a sexually forthright Ecotopian woman and undertakes a relationship whose intensity will lead him to a critical choice between two worlds.

    Joshua Mezrich creates life from loss, transplanting organs from one body to another. In this intimate, profoundly moving work, he illuminates the extraordinary field of transplantation that enables this kind of miracle to happen every day.When Death Becomes Life is a thrilling look at how science advances on a grand scale to improve human lives. Mezrich examines more than one hundred years of remarkable medical breakthroughs, connecting this fascinating history with the inspiring and heartbreaking stories of his transplant patients. Combining gentle sensitivity with scientific clarity, Mezrich reflects on his calling as a doctor and introduces the modern pioneers who made transplantation a reality—maverick surgeons whose feats of imagination, bold vision, and daring risk taking generated techniques and practices that save millions of lives around the world.Mezrich takes us inside the operating room and unlocks the wondrous process of transplant surgery, a delicate, intense ballet requiring precise timing, breathtaking skill, and at times, creative improvisation. In illuminating this work, Mezrich touches the essence of existence and what it means to be alive. Most physicians fight death, but in transplantation, doctors take from death. Mezrich shares his gratitude and awe for the privilege of being part of this transformative exchange as the dead give their last breath of life to the living. After all, the donors are his patients, too.When Death Becomes Life also engages in fascinating ethical and philosophical debates: How much risk should a healthy person be allowed to take to save someone she loves? Should a patient suffering from alcoholism receive a healthy liver? What defines death, and what role did organ transplantation play in that definition? The human story behind the most exceptional medicine of our time, Mezrich’s riveting book is a beautiful, poignant reminder that a life lost can also offer the hope of a new beginning.

    Numbly, he makes his way back home. On the plane, he encounters the enigmatic Mr Wednesday, who claims to be a refugee from a distant war, a former god and the king of America. Together they embark on a profoundly strange journey across the heart of the USA, whilst all around them a storm of preternatural and epic proportions threatens to break.Scary, gripping and deeply unsettling, American Gods takes a long, hard look into the soul of America. You'll be surprised by what - and who - it finds there...