An epic, first-of-its-kind book, entwining leading-edge scientific discovery with the intimate stories of four individual lives, by the Pulitzer Prize–winning New York Times journalist.A terminal cancer patient rises from the grave. A medical marvel defies HIV. Two women with autoimmunity discover their own bodies have turned against them. Matt Richtel's An Elegant Defense uniquely entwines these intimate stories with science’s centuries-long quest to unlock the mysteries of sickness and health, and illuminates the immune system as never before.The immune system is our body’s essential defense network, a guardian vigilantly fighting illness, healing wounds, maintaining order and balance, and keeping us alive. Its legion of microscopic foot soldiers—from T cells to “natural killers”—patrols our body, linked by a nearly instantaneous communications grid. It has been honed by evolution over millennia to face an almost infinite array of threats.For all its astonishing complexity, however, the immune system can be easily compromised by fatigue, stress, toxins, advanced age, and poor nutrition—hallmarks of modern life—and even by excessive hygiene. Paradoxically, it is a fragile wonder weapon that can turn on our own bodies with startling results, leading today to epidemic levels of autoimmune disorders.Richtel effortlessly guides readers on a scientific detective tale winding from the Black Plague to twentieth-century breakthroughs in vaccination and antibiotics, to the cutting-edge laboratories that are revolutionizing immunology—perhaps the most extraordinary and consequential medical story of our time. The foundation that Richtel builds makes accessible revelations about cancer immunotherapy, the microbiome, and autoimmune treatments that are changing millions of lives. An Elegant Defense also captures in vivid detail how these powerful therapies, along with our behavior and environment, interact with the immune system, often for the good but always on a razor’s edge that can throw this remarkable system out of balance.Drawing on his groundbreaking reporting for the New York Times and based on extensive new interviews with dozens of world-renowned scientists, Matt Richtel has produced a landmark book, equally an investigation into the deepest riddles of survival and a profoundly human tale that is movingly brought to life through the eyes of his four main characters, each of whom illuminates an essential facet of our “elegant defense.”

    In a sex-positive incantation that retextures what it is to write a queer life amidst troubled times, Garcia writes boldly of citizenship, family, and Adam Rippon’s butt. Detailing a childhood spent undocumented, one speaker recalls nights when “because we cannot sleep / we dream with open eyes.” Garcia delves with both English and Spanish into how one survives a country’s long love affair with anti-immigrant cruelty. Rendering a family working to the very end to hold each other, he writes the kind of family you both survive and survive with.With language that arrives equal parts regal and raucous, Thrown in the Throat shines brilliant with sweat and an iridescent voice. “Sometimes even a diamond was once alive” writes Garcia in a collection that National Poetry Series judge Kazim Ali says “has deadly superpowers.” And indeed these poems arrive to our hands through touch-me-nots and the slight cruelty of mothers, through closets both real and metaphorical. These are poems complex, unabashed, and needed as survival. Garcia’s debut is nothing less than exactly the ode our history and present and our future call for: brash and unmistakably alive.

      Along the way, he reveals the untold story of Hans Asperger, the father of Asperger’s syndrome, whose “little professors” were targeted by the darkest social-engineering experiment in human history; exposes the covert campaign by child psychiatrist Leo Kanner to suppress knowledge of the autism spectrum for fifty years; and casts light on the growing movement of "neurodiversity" activists seeking respect, support, technological innovation, accommodations in the workplace and in education, and the right to self-determination for those with cognitive differences.

    How does the antique taxidermy in a natural science museum relate to the living birds outside the window? How do the opals found by campers, stored in mineral oil to conserve the water trapped inside, relate to the water table? “My practice is observation. How do relationships illuminate?” Using such models as Joseph Cornell’s box constructions, crazy quilts, and specimen displays, Tevis places fragments in relationship to each other in order to puzzle out lost histories, particularly those of women. Throughout The Wet Collection, the narrator navigates the peril and excitement of an outward journey complicated by an inward longing for home.

    In Life of the Party, she weaves together her own coming of age with an investigation into our culture's romanticization of violence against women. In precise, searing language—at times blistering and riotous, at times soulful and exuberant—she explores the boundary between what is real and what is imagined in a life saturated with fear. How does one grow from a girl to a woman in a world wracked by violence? Where is the line between perpetrator and victim? What is the meaning of bravery? Visceral and haunting, this multifaceted collection illustrates that what happens to our bodies makes us who we are.

    So begins Yusef Salaam telling his story. No one's life is the sum of the worst things that happened to them, and during Yusef Salaam's seven years of wrongful incarceration as one of the Central Park Five, he grew from child to man, and gained a spiritual perspective on life. Yusef learned that we're all "born on purpose, with a purpose." Despite having confronted the racist heart of America while being "run over by the spiked wheels of injustice," Yusef channeled his energy and pain into something positive, not just for himself but for other marginalized people and communities.Better Not Bitter is the first time that one of the now Exonerated Five is telling his individual story, in his own words. Yusef writes his narrative: growing up Black in central Harlem in the '80s, being raised by a strong, fierce mother and grandmother, his years of incarceration, his reentry, and exoneration. Yusef connects these stories to lessons and principles he learned that gave him the power to survive through the worst of life's experiences. He inspires readers to accept their own path, to understand their own sense of purpose. With his intimate personal insights, Yusef unpacks the systems built and designed for profit and the oppression of Black and Brown people. He inspires readers to channel their fury into action, and through the spiritual, to turn that anger and trauma into a constructive force that lives alongside accountability and mobilizes change.This memoir is an inspiring story that grew out of one of the gravest miscarriages of justice, one that not only speaks to a moment in time or the rage-filled present, but reflects a 400-year history of a nation's inability to be held accountable for its sins. Yusef Salaam's message is vital for our times, a motivating resource for enacting change. Better, Not Bitter has the power to soothe, inspire and transform. It is a galvanizing call to action.

    Looking at life through the eyes of Sloth, Bear, Koala, and even Blob Fish, these animals tell the stories of the raw beauty of life on our planet, encouraging us to let go of fear, stick our fingers/paws up at societal pressure, and love ourselves and one another with abandon.

    After oil was discovered beneath their land, the Osage rode in chauffeured automobiles, built mansions, and sent their children to study in Europe.Then, one by one, they began to be killed off. One Osage woman, Mollie Burkhart, watched as her family was murdered. Her older sister was shot. Her mother was then slowly poisoned. And it was just the beginning, as more Osage began to die under mysterious circumstances.In this last remnant of the Wild West—where oilmen like J. P. Getty made their fortunes and where desperadoes such as Al Spencer, “the Phantom Terror,” roamed – virtually anyone who dared to investigate the killings were themselves murdered. As the death toll surpassed more than twenty-four Osage, the newly created F.B.I. took up the case, in what became one of the organization’s first major homicide investigations. But the bureau was then notoriously corrupt and initially bungled the case. Eventually the young director, J. Edgar Hoover, turned to a former Texas Ranger named Tom White to try to unravel the mystery. White put together an undercover team, including one of the only Native American agents in the bureau. They infiltrated the region, struggling to adopt the latest modern techniques of detection. Together with the Osage they began to expose one of the most sinister conspiracies in American history.A true-life murder mystery about one of the most monstrous crimes in American history.

     A riveting, powerful telling of the story of the grassroots movement of activists, many of them in a life-or-death struggle, who seized upon scientific research to help develop the drugs that turned HIV from a mostly fatal infection to a manageable disease. Ignored by public officials, religious leaders, and the nation at large, and confronted with shame and hatred, this small group of men and women chose to fight for their right to live by educating themselves and demanding to become full partners in the race for effective treatments. Around the globe, 16 million people are alive today thanks to their efforts. Not since the publication of Randy Shilts's classic And the Band Played On has a book measured the AIDS plague in such brutally human, intimate, and soaring terms. In dramatic fashion, we witness the founding of ACT UP and TAG (Treatment Action Group), and the rise of an underground drug market in opposition to the prohibitively expensive (and sometimes toxic) AZT. We watch as these activists learn to become their own researchers, lobbyists, drug smugglers, and clinicians, establishing their own newspapers, research journals, and laboratories, and as they go on to force reform in the nation s disease-fighting agencies. With his unparalleled access to this community David France illuminates the lives of extraordinary characters, including the closeted Wall Street trader-turned-activist, the high school dropout who found purpose battling pharmaceutical giants in New York, the South African physician who helped establish the first officially recognized buyers club at the height of the epidemic, and the public relations executive fighting to save his own life for the sake of his young daughter. Expansive yet richly detailed, this is an insider's account of a pivotal moment in the history of American civil rights. Powerful, heart-wrenching, and finally exhilarating, How to Survive a Plague is destined to become an essential part of the literature of AIDS.

    It is almost entirely true." Thus begins Esi Edugyan's 2013 Henry Kreisel Memorial Lecture. With the finesse of a writer who is in complete control of the worlds she creates, Esi Edugyan guides readers through her experience of home and belonging. She moves effortlessly from cities in Canada and Germany to the bustle of Accra, Ghana, as she finds her identity in the diaspora. Readers interested in travel, literature, and the post-colonial search for belonging will become her willing travel companions on this journey.

    Where twentiethcentury psychology focused on depression and illness, in the new millennium scientists have begun focusing on "positive psychology"--the study of happiness. Ariel Gore first became intrigued by this subject when she discovered that Positive Psychology was the most popular course on the Harvard campus. As she read deeper into the topic, she noticed something disturbing: everyone in this happy land was a man. Worse still, some of these new "experts" seemed hell-bent on proving that women with traditional values and breadwinning husbands--those who had made "an effort to expect less," according to one sociologist--were more content than women with feminist values. The more she read the more she wondered: Can a woman be smart, empowered, "and "happy? Determined to find out, Gore began her own "study in living"-- a journey into the feminine history, science, and experience of happiness. Her results, chronicled with humor and curiosity in "Bluebird," are by turns fascinating and enriching. A woman's happiness may not come easy, and it may not take the forms prescribed by popular culture. But, as Gore discovers, it is not only possible but necessary. "Bluebird "is a smart, no-nonsense, uplifting study of the "real "secret of joy, and whether it's truly at odds with the goals of modern women.

    Kristof and Sheryl WuDunn as our guides, we undertake an odyssey through Africa and Asia to meet the extraordinary women struggling there, among them a Cambodian teenager sold into sex slavery and an Ethiopian woman who suffered devastating injuries in childbirth. Drawing on the breadth of their combined reporting experience, Kristof and WuDunn depict our world with anger, sadness, clarity, and, ultimately, hope.They show how a little help can transform the lives of women and girls abroad. That Cambodian girl eventually escaped from her brothel and, with assistance from an aid group, built a thriving retail business that supports her family. The Ethiopian woman had her injuries repaired and in time became a surgeon. A Zimbabwean mother of five, counseled to return to school, earned her doctorate and became an expert on AIDS.Through these stories, Kristof and WuDunn help us see that the key to economic progress lies in unleashing women’s potential. They make clear how so many people have helped to do just that, and how we can each do our part. Throughout much of the world, the greatest unexploited economic resource is the female half of the population. Countries such as China have prospered precisely because they emancipated women and brought them into the formal economy. Unleashing that process globally is not only the right thing to do; it’s also the best strategy for fighting poverty.Deeply felt, pragmatic, and inspirational, Half the Sky is essential reading for every global citizen.

    Strongly political, the poem touches on issues of racism, intolerance, and environmental destruction, amongst others.

    Some stories are funny, some poetic, some vulgar, and some are a little disturbing. Each story has been lovingly crafted to amuse and entertain you in six words.Six Word Wonder is a social media sensation, with over 10,000 followers on Instagram @sixwordwonderNow, for the first time, Doug brings his best tiny stories together in one collection. Unlocking the cage, she stepped out.Cupid. Tomorrow, aim for his head.Home alone, but toilet just flushed.Baby loves whining. Mother loves wine.…reader. I’m a very gifted mind…I poured two glasses… then remembered.Take a moment out of your hectic schedule to enjoy a Six Word Wonder.

    As Shaughnessy conjures our potential future, she movingly (and often with humor) envisions an age where cephalopods might rule over humankind, a fate she suggests we may just deserve after destroying their oceans. These heartbreaking, terrified poems are the battle cry of a woman who is fighting for the survival of the world she loves, and a stirring exhibition of who we are as a civilization.