Our intimate connection with the world, skin protects us while advertising our health, our identity, and our individuality. This dazzling synthetic overview, written with a poetic touch and taking many intriguing side excursions, is a complete guidebook to the pliable covering that makes us who we are. Skin: A Natural History celebrates the evolution of three unique attributes of human skin: its naked sweatiness, its distinctive sepia rainbow of colors, and its remarkable range of decorations. Jablonski begins with a look at skin's structure and functions and then tours its three-hundred-million-year evolution, delving into such topics as the importance of touch and how the skin reflects and affects emotions. She examines the modern human obsession with age-related changes in skin, especially wrinkles. She then turns to skin as a canvas for self-expression, exploring our use of cosmetics, body paint, tattooing, and scarification. Skin: A Natural History places the rich cultural canvas of skin within its broader biological context for the first time, and the result is a tremendously engaging look at ourselves.

    As gripping as CSI and as eye-opening as Mary Roach’s Stiff, Carney’s The Red Market sheds a blazing new light on the disturbing, billion-dollar business of trading in human body parts, bodies, and child trafficking, raising issues and exposing corruptions almost too bizarre and shocking to imagine.

    That scientist, David Hungerford, had no way of knowing that he had stumbled upon the starting point of modern cancer research—the Philadelphia chromosome. This book charts not only that landmark discovery, but also—for the first time, all in one place—the full sequence of scientific and medical discoveries that brought about the first-ever successful treatment of a lethal cancer at the genetic level.The significance of this mutant chromosome would take more than three decades to unravel; in 1990, it was recognized as the sole cause of a deadly blood cancer, chronic myeloid leukemia, or CML. This dramatic discovery launched a race involving doctors and researchers around the world, who recognized that in principle it might be possible to target CML at its genetic source.Science journalist Jessica Wapner brings extensive original reporting to this book, including interviews with more than thirty-five people with a direct role in this story. Wapner reconstructs more than forty years of crucial breakthroughs, clearly explains the science behind them, and pays tribute to the dozens of researchers, doctors, and patients whose curiosity and determination restored the promise of a future to the more than 70,000 people worldwide who are diagnosed with CML each year. Chief among them is researcher and oncologist Dr. Brian Druker, whose dedication to his patients fueled his quest to do everything within his power to save them.The Philadelphia Chromosome helps us to fully understand and appreciate just how pathbreaking, hard-won, and consequential are the achievements it recounts—and to understand the principles behind much of today’s most important cancer research, as doctors and scientists race to uncover and treat the genetic roots of a wide range of cancers.

    "I was born in the month of July, and my horoscope sign is a disease (Cancer). The symbol for Cancer? A crab (the sexually transmitted critter). Not only that, my parents named me Shawn Timothy Decker, which makes my initials S.T.D. Shawn Decker isn't quite the all-American boy. Sure, he gets caught shoplifting copies of Penthouse, is crazy about pro wrestling, especially "The Nature Boy" Ric Flair, and never has a problem getting dates. But he's also a hemophiliac who discovers, at age eleven, that he has contracted HIV from tainted blood products. Instead of becoming self-pitying and dying (as first predicted), Shawn develops a twisted sense of humor, meets Depeche Mode through the Make-A-Wish Foundation, and writes on blogs and in Poz magazine about what it's like being hetero and HIV-positive in rural Virginia. He also turns to gay men for advice on dating women and, almost twenty years after getting HIV, marries Gwenn Barringer, who is HIV-negative and a former competitor for the title of Miss Virginia. Together Shawn and Gwenn travel the country, speaking to high school and college kids about how to live and love with HIV (and how to avoid getting it).

    Frances Mayes offers her readers a deeply personal memoir of her present-day life in Tuscany, encompassing both the changes she has experienced since Under the Tuscan Sun and Bella Tuscany appeared, and sensuous, evocative reflections on the timeless beauty and vivid pleasures of Italian life. Among the themes Mayes explores are how her experience of Tuscany dramatically expanded when she renovated and became a part-time resident of a 13th century house with a stone roofin the mountains above Cortona, how life in the mountains introduced her to a "wilder" side of Tuscany--and with it a lively engagement with Tuscany's mountain people. Throughout, she reveals the concrete joys of life in her adopted hill town, with particular attention tolife in the piazza, the art of Luca Signorelli (Renaissance painter from Cortona), and the pastoral pleasures of feasting from her garden.Moving always toward a deeper engagement, Mayes writes of Tuscan icons thathave become for her storehouses of memory, of crucible moments from which bigger ideas emerged, andof the writing life she has enjoyed in the room where Under the Tuscan Sun began. With more on the pleasures of life at Bramasole, the delights and challenges of living in Italy day-to-day and favorite recipes, Every Day in Tuscany is a passionate and inviting account of the richness and complexity of Italian life."

    James Rebanks' isn't. The first son of a shepherd, who was the first son of a shepherd himself, he and his family have lived and worked in and around the Lake District for generations. Their way of life is ordered by the seasons and the work they demand, and has been for hundreds of years. A Viking would understand the work they do: sending the sheep to the fells in the summer and making the hay; the autumn fairs where the flocks are replenished; the gruelling toil of winter when the sheep must be kept alive, and the light-headedness that comes with spring, as the lambs are born and the sheep get ready to return to the fells.

    In 1905 an unknown 26-year-old clerk at the Swiss Patent Office, who had supposedly failed math in school, burst on to the scientific scene and swept away the hidebound theories of the day. The clerk, Albert Einstein, introduced a new and unexpected understanding of the universe and launched the two great revolutions of twentieth-century physics, relativity and quantum mechanics. The obscure origin and wide-ranging brilliance of the work recalled Isaac Newton’s “annus mirabilis” (miracle year) of 1666, when as a 23-year-old seeking safety at his family manor from an outbreak of the plague, he invented calculus and laid the foundations for his theory of gravity. Like Newton, Einstein quickly became a scientific icon--the image of genius and, according to Time magazine, the Person of the Century.The actual story is much more interesting. Einstein himself once remarked that “science as something coming into being ... is just as subjectively, psychologically conditioned as are all other human endeavors.” In this profile, the historian of science L. Randles Lagerstrom takes you behind the myth and into the very human life of the young Einstein. From family rifts and girlfriend troubles to financial hardships and jobless anxieties, Einstein’s early years were typical of many young persons. And yet in the midst of it all, he also saw his way through to profound scientific insights. Drawing upon correspondence from Einstein, his family, and his friends, Lagerstrom brings to life the young Einstein and enables the reader to come away with a fuller and more appreciative understanding of Einstein the person and the origins of his revolutionary ideas.About the cover image: While walking to work six days a week as a patent clerk in Bern, Switzerland, Einstein would pass by the famous "Zytglogge" tower and its astronomical clocks. The daily juxtaposition was fitting, as the relative nature of time and clock synchronization would be one of his revolutionary discoveries in the miracle year of 1905.

    Marieb and Katja Hoehn have produced the most accessible, comprehensive, up-to-date, and visually stunning anatomy & physiology textbook on the market. Marieb draws on her career as an A&P professor and her experience as a part-time nursing student, while Hoehn relies on her medical education and classroom experience to explain concepts and processes in a meaningful and memorable way. The most significant revision to date, the Eighth Edition makes it easier for you to learn key concepts in A&P. The new edition features a whole new art program that is not only more visually dynamic and vibrant than in previous editions but is also much more pedagogically effective for today's students, including new Focus figures, which guide you through the toughest concepts in A&P. The text has been edited to make it easier than ever to study from and navigate, with integrated objectives, new concept check questions, and a new design program.

    Visiting it almost daily for one year to trace nature’s path through the seasons, he brings the forest and its inhabitants to vivid life.Each of this book’s short chapters begins with a simple observation: a salamander scuttling across the leaf litter; the first blossom of spring wildflowers. From these, Haskell spins a brilliant web of biology and ecology, explaining the science that binds together the tiniest microbes and the largest mammals and describing the ecosystems that have cycled for thousands—sometimes millions—of years. Each visit to the forest presents a nature story in miniature as Haskell elegantly teases out the intricate relationships that order the creatures and plants that call it home.Written with remarkable grace and empathy, The Forest Unseen is a grand tour of nature in all its profundity. Haskell is a perfect guide into the world that exists beneath our feet and beyond our backyards.

    This book can be cut, drawn in, folded into shapes and will even take you to the fourth dimension. So join stand-up mathematician Matt Parker on a journey through narcissistic numbers, optimal dating algorithms, at least two different kinds of infinity and more.

    David Starr Jordan was a taxonomist, a man possessed with bringing order to the natural world. In time, he would be credited with discovering nearly a fifth of the fish known to humans in his day. But the more of the hidden blueprint of life he uncovered, the harder the universe seemed to try to thwart him. His specimen collections were demolished by lightning, by fire, and eventually by the 1906 San Francisco earthquake—which sent more than a thousand of his discoveries, housed in fragile glass jars, plummeting to the floor. In an instant, his life’s work was shattered. Many might have given up, given in to despair. But Jordan? He surveyed the wreckage at his feet, found the first fish he recognized, and confidently began to rebuild his collection. And this time, he introduced one clever innovation that he believed would at last protect his work against the chaos of the world. When NPR reporter Lulu Miller first heard this anecdote in passing, she took Jordan for a fool—a cautionary tale in hubris, or denial. But as her own life slowly unraveled, she began to wonder about him. Perhaps instead he was a model for how to go on when all seemed lost. What she would unearth about his life would transform her understanding of history, morality, and the world beneath her feet. Part biography, part memoir, part scientific adventure, Why Fish Don’t Exist reads like a fable about how to persevere in a world where chaos will always prevail.

    In 1903, while on a three-day camping trip with President Theodore Roosevelt, he convinced the president of the importance of a national conservation program, and he is widely recognized for saving the Grand Canyon and Arizona's Petrified Forest. Muir's writing, based on journals he kept throughout his life, gives our generation a picture of an America still wild and unsettled only one hundred years ago. In The Wildernesss World of John Muir Edwin Way Teale has selected the best of Muir's writing from all of his major works—including My First Summer in the Sierra and Travels in Alaska—to provide a singular collection that provides to be "magnificent, thrilling, exciting, breathtaking, and awe-inspiring" (Kirkus Reviews).

    A writer for The New Yorker and The Atlantic Monthly, Carl Elliott ventures into the uncharted dark side of medicine, shining a light on the series of social and legislative changes that have sacrificed old-style doctoring to the values of consumer capitalism. Along the way, he introduces us to the often shifty characters who work the production line in Big Pharma: from the professional guinea pigs who test-pilot new drugs and the ghostwriters who pen “scientific” articles for drug manufacturers to the PR specialists who manufacture “news” bulletins. We meet the drug reps who will do practically anything to make quota in an ever-expanding arms race of pharmaceutical gift-giving; the “thought leaders” who travel the world to enlighten the medical community about the wonders of the latest release; even, finally, the ethicists who oversee all that commercialized medicine has to offer from their pharma-funded perches.   Taking the pulse of the medical community today, Elliott discovers the culture of deception that has become so institutionalized many people do not even see it as a problem. Head-turning stories and a rogue’s gallery of colorful characters become his springboard for exploring larger ethical issues surrounding money. Are there certain things that should not be bought and sold? In what ways do the ethics of business clash with the ethics of medical care? And what is wrong with medical consumerism anyway? Elliott asks all these questions and more as he examines the underbelly of medicine.

    Cohen show us that the antidote to our ever-growing rates of obesity and chronic diseases, such as heart disease and diabetes, lies not in our medical care system or in more health education but rather in how our environment affects our behavior.

    From his intimate knowledge of S., the mnemonist, gained from conversations and testing over a period of almost thirty years, A. R. Luria is able to reveal in rich detail not only the obvious strengths of S.’s astonishing memory but also his surprising weaknesses: his crippling inability to forget, his pattern of reacting passively to life, and his uniquely handicapped personality.