But if we are supposedly evolution’s greatest creation, why do we have such bad knees? Why do we catch head colds so often—two hundred times more often than a dog does? How come our wrists have so many useless bones? Why is the vast majority of our genetic code pointless? And are we really supposed to swallow and breathe through the same narrow tube? Surely there’s been some kind of mistake. As professor of biology Nathan H. Lents explains in Human Errors, our evolutionary history is nothing if not a litany of mistakes, each more entertaining and enlightening than the last. The human body is one big pile of compromises. But that is also a testament to our greatness: as Lents shows, humans have so many design flaws precisely because we are very, very good at getting around them.   A rollicking, deeply informative tour of humans’ four billion year long evolutionary saga, Human Errors both celebrates our imperfections and offers an unconventional accounting of the cost of our success.

    This discovery prompted a complete reevaluation of previous evidence for human origins.In the years since this dramatic discovery Johanson has continued to scour East Africa's Great rift Valley for the earliest evidence of human origins. In 1975 this team unearthed the "First Family", an unparalleled fossil assemblage of 13 individuals dating back to 3.2 million years ago; and in 1986 at the Rift's most famous location, Olduvai Gorge, this same team discovered a 1.8 million-year-old partial adult skeleton that necessitated a reassessment of the earliest members of our own genus Homo.Johanson's fieldwork continues unabated and recently more fossil members of Lucy's family have been found, including the 1992 discovery of the oldest, most complete skull of her species, with future research now planned for 1996 in the virtually unexplored regions of the most northern extension of the Rift Valley in Eritrea.From Lucy to Language is a summing up of this remarkable career and a stunning documentary of human life through time on Earth. It is a combination of the vital experience of field work and the intellectual rigor of primary research. It is the fusion of two great writing talents: Johanson and Blake Edgar, an accomplished science writer, editor of the California Academy of Sciences' Pacific Discovery, and co-author of Johanson's last book, Ancestors.From Lucy to Language is one of the greatest stories ever told, bracketing the timeline between bipedalism and human language. Part I addresses the central issues facing anyone seeking to decipher the mystery of human origins. In this section the authors provide answers to the basics -- "What are our closest living relatives?" -- tackle the controversial -- "What is race?" -- and contemplate the imponderables -- "Why did consciousness evolve?"From Lucy to Language is an encounter with the evidence. Early human fossils are hunted, discovered, identified, excavated, collected, preserved, labeled, cleaned, reconstructed, drawn, fondled, photographed, cast, compared, measured, revered, pondered, published, and argued over endlessly. Fossils like Lucy have become a talisman of sorts, promising to reveal the deepest secrets of our existence. In Part II the authors profile over fifty of the most significant early human fossils ever found. Each specimen is displayed in color and at actual size, most of them in multiple views. With them the authors present the cultural accoutrements associated with the fossils: stone tools which evidence increasing sophistication over time, the earliest stone, clay, and ivory art objects, and the culminating achievement of the dawn of human consciousness -- the magnificent rock and cave paintings of Europe, Africa, Australia, and the Americas.In the end From Lucy to Language is a reminder and a challenge. Like no species before us, we now seem poised to control vast parts of the planet and its life. We possess the power to influence, if not govern, evolution. For that reason, we must not forget our link to the natural world and our debt to natural selection. We need to "think deep", to add a dose of geologic time and evolutionary history to our perspective of who we are, where we came from, and where we are headed. This is the most poignant lesson this book has to offer.

    Science has seen its fair share of punch-ups over the years, but one debate, in the field of biology, has become notorious for its intensity. Over the last twenty years, Richard Dawkins and Stephen Jay Gould have engaged in a savage battle over evolution, which continues to rage even after Gould's death in 2002. Kim Sterelny moves beyond caricature to expose the real differences between the conceptions of evolution of these two leading scientists. He shows that the conflict extends beyond evolution to their very beliefs in science itself; and, in Gould?s case, to domains in which science plays no role at all.

    Building a house would entail no more work than planting a seed in the ground. These scenarios may seem far-fetched, but pioneering geneticist George Church and science writer Ed Regis show that synthetic biology is bringing us ever closer to making such visions a reality. In Regenesis, Church and Regis explore the possibilities—and perils—of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. Until now, nature has been the exclusive arbiter of life, death, and evolution; with synthetic biology, we now have the potential to write our own biological future. Indeed, as Church and Regis show, it even enables us to revisit crucial points in the evolution of life and, through synthetic biological techniques, choose different paths from those nature originally took. Such exploits will involve far more than just microbial tinkering. Full-blown genomic engineering will make possible incredible feats, from resurrecting woolly mammoths and other extinct organisms to creating mirror life forms with a molecular structure the opposite of our own. These technologies—far from the out-of-control nightmare depicted in science fiction—have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span. A breathtaking look at the potential of this world-changing technology, Regenesis is nothing less than a guide to the future of life.

    It develops an understanding of function and evolution into the discussion of anatomy of the various systems.

    His simple but staggering theory of quantum evolution shows how quantum mechanics gives living organisms the ability to initiate specific actions, including new mutations. As Paul Davies exclaims, "if these ideas are right, they will transform our understanding of the relationship between physics and biology" and may radically revise the notion of random evolution and the debate over consciousness and free will.

    In One Renegade Cell, Weinberg presents a state-of-the-art account of how cancer begins and how, one day, it will be cured.

    But things didn't turn out that way. For a start, we turned out to have far fewer genes than originally thought - just over 20,000, the same sort of number as a fruit fly or worm. What's more, the proportionof DNA consisting of genes coding for proteins was a mere 2%. So, was the rest of the genome accumulated 'junk'?Things have changed since those early heady days of the Human Genome Project. But the emerging picture is if anything far more exciting. In this book, John Parrington explains the key features that are coming to light - some, such as the results of the international ENCODE programme, still much debated and controversial in their scope. He gives an outline of the deeper genome, involving layers of regulatory elements controlling and coordinating the switching on and off of genes; the impact ofits 3D geometry; the discovery of a variety of new RNAs playing critical roles; the epigenetic changes influenced by the environment and life experiences that can make identical twins different and be passed on to the next generation; and the clues coming out of comparisons with the genomes ofNeanderthals as well as that of chimps about the development our species. We are learning more about ourselves, and about the genetic aspects of many diseases. But in its complexity, flexibility, and ability to respond to environmental cues, the human genome is proving to be far more subtle than we ever imagined.

    In doing so, the authors synthesize information from astronomy, biology, and paleontology, and apply it to what we know about the rise of life on Earth and to what could possibly happen elsewhere in the universe. Everyone who has been thrilled by the recent discoveries of extrasolar planets and the indications of life on Mars and the Jovian moon Europa will be fascinated by Rare Earth, and its implications for those who look to the heavens for companionship.

    In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field—the study of life’s diversity and relatedness at the molecular level—is horizontal gene transfer (HGT), or the movement of genes across species lines. It turns out that HGT has been widespread and important. For instance, we now know that roughly eight percent of the human genome arrived not through traditional inheritance from directly ancestral forms, but sideways by viral infection—a type of HGT.David Quammen chronicles these discoveries through the lives of the researchers who made them—such as Carl Woese, the most important little-known biologist of the twentieth century; Lynn Margulis, the notorious maverick whose wild ideas about “mosaic” creatures proved to be true; and Tsutomu Wantanabe, who discovered that the scourge of antibiotic-resistant bacteria is a direct result of horizontal gene transfer, bringing the deep study of genome histories to bear on a global crisis in public health.

      Leonard Mlodinow takes us on a passionate and inspiring tour through the exciting history of human progress and the key events in the development of science. In the process, he presents a fascinating new look at the unique characteristics of our species and our society that helped propel us from stone tools to written language and through the birth of chemistry, biology, and modern physics to today’s technological world.   Along the way he explores the cultural conditions that influenced scientific thought through the ages and the colorful personalities of some of the great philosophers, scientists, and thinkers: Galileo, who preferred painting and poetry to medicine and dropped out of university; Isaac Newton, who stuck needlelike bodkins into his eyes to better understand changes in light and color; and Antoine Lavoisier, who drank nothing but milk for two weeks to examine its effects on his body. Charles Darwin, Albert Einstein, Werner Heisenberg, and many lesser-known but equally brilliant minds also populate these pages, each of their stories showing how much of human achievement can be attributed to the stubborn pursuit of simple questions (why? how?), bravely asked.  The Upright Thinkers is a book for science lovers and for anyone interested in creative thinking and in our ongoing quest to understand our world. At once deeply informed, accessible, and infused with the author’s trademark wit, this insightful work is a stunning tribute to humanity’s intellectual curiosity.  (With black-and-white illustrations throughout.)

    Increased emphasis on gene activity, signal transduction and the emphasis on the roles of paracrine factors in development.

    But in The Music of Life, world renowned physiologist Denis Noble argues that, to truly understand life, we must look beyondthe selfish gene to consider life on a much wider variety of levels. Life, Noble asserts, is a kind of music, a symphonic interplay between genes, cells, organs, body, and environment. He weaves this musical metaphor throughout this personal and deeply lyrical work, illuminating ideas that might otherwise be daunting to non-scientists. In elegant prose, Noblesets out a cutting-edge alternative to the gene's eye view, offering a radical switch of perception in which genes are seen as prisoners and the organism itself is a complex system of many interacting levels. In his more expansive view, life emerges as a process, the ebb and flow of activity in anintricate web of connections. He introduces readers to the realm of systems biology, a field that has been growing in strength in the past decade. Noble, himself one of the founders of this field, argues modern systems biology may be the view we need to adopt to gain a deeper understanding of thenature of life. Drawing on his experiences in his research on the heartbeat, and on evolutionary biology, development, medicine, philosophy, linguistics, and Chinese culture, Noble presents us with a profound and very modern reflection on the nature of life.

    So how does chemistry give rise to biology? What could have led the first replicating molecules up such a path? Now, developments in the emerging field of 'systems chemistry' are unlocking the problem. Addy Pross shows how the different kind of stability that operates among replicating molecules results in a tendency for chemical systems to become more complex and acquire the properties of life. Strikingly, he demonstrates that Darwinian evolution is the biological expression of a deeper, well-defined chemical concept: the whole story from replicating molecules to complex life is one continuous process governed by an underlying physical principle. The gulf between biology and the physical sciences is finally becoming bridged.

    Now, faced with the threat of nuclear weapons and the effects of climate change, it seems our innate tendencies for violence and invention have led us to a crucial fork in our road. Where did these traits come from? Are they part of our species immutable destiny? Or is there hope for our species’ future if we change? With fascinating facts and his unparalleled readability, Diamond intended his book to improve the world that today’s young people will inherit. Triangle Square’s The Third Chimpanzee for Young People is a book for future generation and the future they’ll help build.