At the time, Watson was only 24, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science's greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions & bitter rivalries. With humility unspoiled by false modesty, Watson relates his & Crick's desperate efforts to beat Linus Pauling to the Holy Grail of life sciences, the identification of the basic building block of life. Never has a scientist been so truthful in capturing in words the flavor of his work.

    The Human Genome Project finished sequencing human DNA. It seemed it was only a matter of time until we had all the answers to the secrets of life on this planet. The cutting-edge of biology, however, is telling us that we still don't even know all of the questions. How is it that, despite each cell in your body carrying exactly the same DNA, you don't have teeth growing out of your eyeballs or toenails on your liver? How is it that identical twins share exactly the same DNA and yet can exhibit dramatic differences in the way that they live and grow? It turns out that cells read the genetic code in DNA more like a script to be interpreted than a mould that replicates the same result each time. This is epigenetics and it's the fastest-moving field in biology today. The Epigenetics Revolution traces the thrilling path this discipline has taken over the last twenty years. Biologist Nessa Carey deftly explains such diverse phenomena as how queen bees and ants control their colonies, why tortoiseshell cats are always female, why some plants need a period of cold before they can flower, why we age, develop disease and become addicted to drugs, and much more. Most excitingly, Carey reveals the amazing possibilities for humankind that epigenetics offers for us all - and in the surprisingly near future.

    

    Indeed, these tiny structures inside our cells are important beyond imagining. Without mitochondria, we would have no cell suicide, no sculpting of embryonic shape, no sexes, no menopause, no aging.In this fascinating and thought-provoking book, Nick Lane brings together the latest research in this exciting field to show how our growing insight into mitochondria has shed light on how complex life evolved, why sex arose (why don't we just bud?), and why we age and die. These findings are of fundamental importance, both in understanding life on Earth, but also in controlling our own illnesses, and delaying our degeneration and death. Readers learn that two billion years ago, mitochondria were probably bacteria living independent lives and that their capture within larger cells was a turning point in the evolution of life, enabling the development of complex organisms. Lane describes how mitochondria have their own DNA and that its genes mutate much faster than those in the nucleus. This high mutation rate lies behind our aging and certain congenital diseases. The latest research suggests that mitochondria play a key role in degenerative diseases such as cancer. We also discover that mitochondrial DNA is passed down almost exclusively via the female line. That's why it has been used by some researchers to trace human ancestry daughter-to-mother, to "Mitochondrial Eve," giving us vital information about our evolutionary history.Written by Nick Lane, a rising star in popular science, Power, Sex, Suicide is the first book for general readers on the nature and function of these tiny, yet fascinating structures.

    After all, we ourselves are the product of evolution, and we can tackle many of our gravest challenges –– from lethal resurgence of antiobiotic–resistant diseases to the wave of extinctions that looms before us –– with a sound understanding of the science.

     Carl Sagan is considered one of the greatest scientific minds of our time. His remarkable ability to explain science in terms easily understandable to the layman in bestselling books such as Cosmos, The Dragons of Eden, and The Demon-Haunted World won him a Pulitzer Prize and placed him firmly next to Isaac Asimov, Stephen Jay Gould, and Oliver Sachs as one of the most important and enduring communicators of science. In December 2006 it will be the tenth anniversary of Sagan's death, and Ann Druyan, his widow and longtime collaborator, will mark the occasion by releasing Sagan's famous "Gifford Lectures in Natural Theology," The Varieties of Scientific Experience: A Personal View of the Search for God. The chance to give the Gifford Lectures is an honor reserved for the most distinguished scientists and philosophers of our civilization. In 1985, on the grand occasion of the centennial of the lectureship, Carl Sagan was invited to give them. He took the opportunity to set down in detail his thoughts on the relationship between religion and science as well as to describe his own personal search to understand the nature of the sacred in the vastness of the cosmos. The Varieties of Scientific Experience, edited, updated and with an introduction by Ann Druyan, is a bit like eavesdropping on a delightfully intimate conversation with the late great astronomer and astrophysicist. In his charmingly down-to-earth voice, Sagan easily discusses his views on topics ranging from manic depression and the possibly chemical nature of transcendance to creationism and so-called intelligent design to the likelihood of intelligent life on other planets to the likelihood of nuclear annihilation of our own to a new concept of science as "informed worship." Exhibiting a breadth of intellect nothing short of astounding, he illuminates his explanations with examples from cosmology, physics, philosophy, literature, psychology, cultural anthropology, mythology, theology, and more. Sagan's humorous, wise, and at times stunningly prophetic observations on some of the greatest mysteries of the cosmos have the invigorating effect of stimulating the intellect, exciting the imagination, and reawakening us to the grandeur of life in the cosmos.

    With black and white illustrations. "Here is a new collection of Gould's unexpected connections between evolution and all manner of subjects, literature high among them. Gathered from his monthly column in "Natural History" magazine, these articles should delight, surprise, and inform his vast readership, as have his six prior volumes of essays. Somehow the light bulb pops on every month as his deadline approaches, some glowing fact pulled out of memory--often a line from Shakespeare or Tennyson--that illumines a generality Gould wishes to discuss. "Nature, red in tooth and claw" (Lord Alfred's line) induces dilations on the extent science can inform moral matters (not much, Gould believes); a remembrance of the infamous Wansee protocol prompts Gould's denunciation of the genocidal looting of evolutionary theory and, by extension, its vulnerability to ignoramuses in general. These two examples of the Gouldian essay method, fortunately, don't foreshadow a gloomy parade of topics: Gould can as easily alight at the fun house where mass culture absorbs ideas about evolution through movies of monsters run amok from Frankenstein to Jurassic Park. In other essays, he plunges directly into matters of evolutionary interpretation but customarily employs a literary twist: who else but Gould could link Edgar Allan Poe with his own area of professional eminence, the paleontology of snails? A discovery awaits in every essay--in every haystack--which solidifies Gould as one of the most eloquent science popularizers writing today."--"Booklist"

    Shubin describes how over the last half-century, scientists have been able to explore how genetic recipes build bodies during embryological development--how these inventions and adaptations occur in a nonprogressive manner in different contexts, at different speeds. Paleontology has been transformed over the last 50 years by tools and techniques of molecular biology--and it is that revolution in our understanding of the evolution of life that Shubin traces here. Each of us is a mosaic of precursors that came about at different times and places, with deep rooted connections across species that Darwin, for all he understood, could never even have imagined.

    He shows how many intellectuals have denied the existence of human nature by embracing three linked dogmas: the Blank Slate (the mind has no innate traits), the Noble Savage (people are born good and corrupted by society), and the Ghost in the Machine (each of us has a soul that makes choices free from biology). Each dogma carries a moral burden, so their defenders have engaged in desperate tactics to discredit the scientists who are now challenging them.Pinker injects calm and rationality into these debates by showing that equality, progress, responsibility, and purpose have nothing to fear from discoveries about a rich human nature. He disarms even the most menacing threats with clear thinking, common sense, and pertinent facts from science and history.Despite its popularity among intellectuals during much of the twentieth century, he argues, the doctrine of the Blank Slate may have done more harm than good. It denies our common humanity and our individual preferences, replaces hardheaded analyses of social problems with feel-good slogans, and distorts our understanding of government, violence, parenting, and the arts.Pinker shows that an acknowledgement of human nature that is grounded in science and common sense, far from being dangerous, can complement insights about the human condition made by millennia of artists and philosophers. All this is done in the style that earned his previous books many prizes and worldwide acclaim: wit, lucidity, and insight into matters great and small.

    However, he is also a card-carrying member of the American Fern Society, and since childhood has been fascinated by these primitive plants and their ability to survive and adapt in many climates. Oaxaca Journal is Sacks's spellbinding account of his trip with a group of fellow fern enthusiasts to the beautiful, history-steeped province of Oaxaca, Mexico. Bringing together Sacks's passion for natural history and the richness of human culture with his sharp eye for detail, Oaxaca Journal is a captivating evocation of a place, its plants, its people, and its myriad wonders.

    Darwin was only too aware of the storm his theory of evolution would provoke but he would surely have raised an incredulous eyebrow at the controversy still raging a century and a half later. Evolution is accepted as scientific fact by all reputable scientists and indeed theologians, yet millions of people continue to question its veracity.In The Greatest Show on Earth Richard Dawkins takes on creationists, including followers of ‘Intelligent Design’ and all those who question the fact of evolution through natural selection. Like a detective arriving on the scene of a crime, he sifts through fascinating layers of scientific facts and disciplines to build a cast-iron case: from the living examples of natural selection in birds and insects; the ‘time clocks’ of trees and radioactive dating that calibrate a timescale for evolution; the fossil record and the traces of our earliest ancestors; to confirmation from molecular biology and genetics. All of this, and much more, bears witness to the truth of evolution.The Greatest Show on Earth comes at a critical time: systematic opposition to the fact of evolution is now flourishing as never before, especially in America. In Britain and elsewhere in the world, teachers witness insidious attempts to undermine the status of science in their classrooms. Richard Dawkins provides unequivocal evidence that boldly and comprehensively rebuts such nonsense. At the same time he shares with us his palpable love of the natural world and the essential role that science plays in its interpretation. Written with elegance, wit and passion, it is hard-hitting, absorbing and totally convincing.

    Gonzalez-Crussi, from the Introduction An international bestseller, translated into eighteen languages, Paul de Kruif’s classic account of the first scientists to see and learn about the microscopic world continues to fascinate new readers. This is a timeless dramatization of the scientists, bacteriologists, doctors, and medical technicians who discovered the microbes and invented the vaccines to counter them. De Kruif writes about how seemingly simple but really fundamental discovers of science—for instance, how a microbe was first viewed in a clear drop of rain water, and when, for the first time, Louis Pasteur discovered that a simple vaccine could save a man from the ravages of rabies by attacking the microbes that cause it.

    When this classic work was first published in 1975, it created a new discipline and started a tumultuous round in the age-old nature versus nurture debate. Although voted by officers and fellows of the international Animal Behavior Society the most important book on animal behavior of all time, Sociobiology is probably more widely known as the object of bitter attacks by social scientists and other scholars who opposed its claim that human social behavior, indeed human nature, has a biological foundation. The controversy surrounding the publication of the book reverberates to the present day.In the introduction to this Twenty-Fifth Anniversary Edition, Edward O. Wilson shows how research in human genetics and neuroscience has strengthened the case for a biological understanding of human nature. Human sociobiology, now often called evolutionary psychology, has in the last quarter of a century emerged as its own field of study, drawing on theory and data from both biology and the social sciences.For its still fresh and beautifully illustrated descriptions of animal societies, and its importance as a crucial step forward in the understanding of human beings, this anniversary edition of Sociobiology: The New Synthesis will be welcomed by a new generation of students and scholars in all branches of learning.

    It intersects with Darwin’s theory of evolution, and collides with the horrors of Nazi eugenics in the 1940s. The gene transforms post-war biology. It reorganizes our understanding of sexuality, temperament, choice and free will. This is a story driven by human ingenuity and obsessive minds – from Charles Darwin and Gregor Mendel to Francis Crick, James Watson and Rosalind Franklin, and the thousands of scientists still working to understand the code of codes.This is an epic, moving history of a scientific idea coming to life, by the author of The Emperor of All Maladies. But woven through The Gene, like a red line, is also an intimate history – the story of Mukherjee’s own family and its recurring pattern of mental illness, reminding us that genetics is vitally relevant to everyday lives. These concerns reverberate even more urgently today as we learn to “read” and “write” the human genome – unleashing the potential to change the fates and identities of our children.Majestic in its ambition, and unflinching in its honesty, The Gene gives us a definitive account of the fundamental unit of heredity – and a vision of both humanity’s past and future.