Leeuwenhoek proceeded to examine the microscopic activity of his spittle, teeth plaque, and feces, and as the result of his findings the field of bacteriology was born. Some two hundred years later, Wilhelm Conrad Roentgen, a professor of theoretical physics at the University of Wurzburg, invited his wife to his laboratory, asked her to place her hand on an unexposed photographic plate, turned on an electric current, and showed this terrified woman a picture of the bones of her hand. And so came the discovery of the X-ray.This absorbing book is the first to describe these and eight other monumental medical discoveries throughout history, bringing to life the scientific pioneers responsible for them and the excitement, frustrations, and jealousies that surrounded the final achievements. Two distinguished physicians, Meyer Friedman and Gerald W. Friedland, have drawn on their many years of experience as well as on that of world-renowned antiquarian book dealers, physician collectors of old and new medical publications, and medical school professors to single out these medical breakthroughs from thousands of candidates, and, in several cases, to provide information never before available. Their engrossing stories of the ten most significant discoveries will be read with enjoyment by anyone fascinated by the mysteries of medicine.

    Michael Mosley'This book is marvellous: buy it, share it, recommend it.... We are fortunate to have dedicated, caring and humble folks such as Doc Morgan on the Critical Care front line. We are even better off when a writer can capture all that this exciting, mad, glorious and even exasperating job means. If you work in healthcare, know somebody that does, or simply inhabit a body then this book is for you: in fact it's critical.' Peter Brindley, Professor of Critical Care Medicine, Anesthesiology, Medical Ethics University of Alberta'Just wonderful. I love the exploration of what it means to survive, at what cost and so on. Such an important factor and it's a real problem with what we do. An old surgeon once told me ‘just because we can, doesn’t mean we should. Operating is the easiest thing in the world, not doing so is incredibly challenging’. A lovely book.' Dr Nikki Stamp FRACS Cardiothoracic and Transplant Surgeon and author of Can You Die of a Broken Heart?‘An illuminating, compassionate insight into the fascinating world of intensive care.’ Leah Hazzard, author of Hard PushedCritical is an intelligent, compelling and profoundly insightful journey into the world of intensive care medicine and the lives of people who have forever been changed by it. Being critically ill means one or more of your vital organs have failed – this could be your lungs, your heart, your kidneys, gut or even your brain. Starting with the first recognised case in which a little girl was saved by intensive care in 1952 in Copenhagen, Matt writes brilliantly about the fascinating history, practices and technology in this newest of all the major medical specialties. Matt guides us around the ICU by guiding us around the body and the different organs, and in this way, we learn not only the stories of many of the patients he’s treated over the years, but also about the various functions different parts of the body.   He draws on his time spent with real patients, on the brink of death, and explains how he and his colleagues fight against the odds to help them live. Happily many of his cases have happy endings, but Matt also writes movingly about those cases which will always remain with him – the cases where the mysteries of the body proved too hard to solve, or diagnoses came too late or made no difference to the outcome.

    These chapters, based on his own experience and on researched fact, which were emailed each week to his editors at Random House, are both personal and poignant, hard hitting and controversial, tackling the issues raised by alternative medicine with total candour and his usual wit. The second half of this book features some of the best of Diamond's writing, including a selection of emails to colleagues and friends, articles from "The Times" and the "Jewish Chronicle" and other publications, together with excerpts from his final notebook. For seven years he wrote an immensely popular weekly column in "The Times" which, following his diagnosis with cancer, was given over to following the progress of the disease. As well as gaining him a Columnist of the Year award, it resulted in an avalanche of mail from thousands of his readers.

    Horton's experiences being thrown into heavy combat after just a few months of training. Recommended reading for all. Survival against all odds - in the trenches of Vietnam - I still can't believe they get out of there alive - couldn't put it down. This first person narrative of hand-to-hand combat in the trenches of Vietnam left me scared, glad to be alive and eternally grateful to those who died for my freedom Could not put it down - A friend had mentioned this book to me. Once I received it I could not put it down. Jerry Horton joined the army to simply be able to afford to go to college. 40 years later he has a PHD and multiple degrees but they were earned at a heavy price for this patriot. Jerry shares his experiences in Vietnam in an articulate, honest and direct assessment of his time in Vietnam, the men he served with and the horrors of war. Incredible story of leadership and survival. Shake N Bake Sergeant aka Instant NCO - Jerry Horton absolutely nailed the life of a "Shake 'n Bake" Sergeant when he tells the story of dedicated soldiers trained at Fort Benning, GA and then follows them to Vietnam. This book is not only absolutely dead on accurate but gives the reader every aspect of what it was like to experience the war as a Shake 'n Bake Sergeant. Instant NCO's were trained for only one reason - to lead United States soldiers into combat and they did it with heroic efficiency and effectiveness with limited resources. This book is not just a home run - it is a Grand Slam. Interesting, accurate, full of suspense and you can't put it down. This book should be required reading for everyone so they can understand that Freedom is not Free. There is a cost and sometimes that cost is heavy. Horton brings it all across in a nonstop action format. It is a great read! If you really want to know what it was like...This has to be the most realistic 'must read' book to come out of the VN war. If you ever read any book about this war - this is the one to read. You won't put it down and you won't ever forget it! From the book's review by the late COL(R) David Hackworth (most-decorated Vietnam veteran): "In 1968, the U.S. Army was running out of sergeants in Vietnam. Throughout military history, as least as far back as the Revolutionary War, sergeants were the backbone of the Army. This shortage of sergeants meant disaster in Vietnam. The NCO candidate school was created to solve this serious problem by doing one thing - train soldiers to lead men in combat. It was modeled after the Officer's candidate school but streamlined to meet this critical need for leaders in half the time. Graduates were known by most as "Shake 'n Bake Sergeants" or "Instant NCOs" since they got their rank fast from going to school. This book is the first time this important part of American history has ever been published. It is the first time anyone has given credit to Shake 'n Bake Sergeants - a credit that they so greatly deserved. At the time there were many who said they would fail. It seemed many did not respect them even though all were destined for front line positions. The book documents how they proved their worth over and over again as front line infantry leaders even though for thirty some years their sacrifices have been unknown." An unforgettable mixture of vivid realism, poignant sadness and unexpected humor. Once you begin reading The Shake 'n Bake Sergeant, you will find it hard to put it down. See www.shakenbakesergeant.com.

    O'Connell’s collection of stories and essays, written during thirty years of caring for homeless persons in Boston, gently illuminates the humanity and raw courage of those who struggle to survive and find meaning and hope while living on the streets.

    Bill Bass, one of the world's leading forensic anthropologists, gained international attention when he built a forensic lab like no other: The Body Farm. Now, this master scientist unlocks the gates of his lab to reveal his most intriguing cases-and to revisit the Lindbergh kidnapping and murder, fifty years after the fact.

    Judy Melinek’s Working Stiff, an account of the hair-raising and heartbreaking cases handled by the coroner of Marin County, California throughout his four decades on the job—from high-profile deaths to serial killers, to Golden Gate Bridge suicides.Marin County, California is a study in contradictions. Its natural beauty attracts thousands of visitors every year, yet the county also is home to San Quentin Prison, one of the oldest and largest penitentiaries in the country. Marin ranks in the top one percent of counties nationwide in terms of affluence and overall health, yet it is far above the norm in drug overdoses and alcoholism, and comprises a large percentage of suicides from the Golden Gate Bridge. Ken Holmes worked in the Marin County Coroner’s Office for thirty-six years, starting as a death investigator and ending as the three-term, elected coroner. As he grew into the job—which is different from what is depicted on television—Holmes learned a variety of skills, from finding hidden clues at death scenes, interviewing witnesses effectively, managing bystanders and reporters, preparing testimony for court to notifying families of a death with sensitivity and compassion. He also learned about different kinds of firearms, all types of drugs—prescription and illegal—and about certain unexpected and potentially fatal phenomena such as autoeroticism. Complete with poignant anecdotes, The Education of a Coroner provides a firsthand and fascinating glimpse into the daily life of a public servant whose work is dark and mysterious yet necessary for society to function.

    Christine Gleason, one of today's most prominent pediatricians, is also a born storyteller who takes readers into life and death situations encountered in the neonatal intensive care unit.

    Carol North was diagnosed with schizophrenia in college. The story of her life is traced from her early life in a middle class small-town family in the Midwest. For many years, Carol struggled against overwhelming odds to achieve in school in spite of her illness and was finally admitted to medical school to pursue her hopes and dreams of becoming a doctor. In medical school, however, she slid further into psychosis and finally succumbed the inexorable incapacitation so often characteristic of the illness. Carol was fortunate enough, however, to find a skilled psychiatrist who understood her dedication to becoming a physician and who worked with her to stay well enough to remain in school. When all hope seemed lost, her doctor enrolled her in an experimental dialysis program, similar to the treatment given to patients with kidney failure. With this treatment, her illness went away and she no longer required medication for it. This engrossing and ultimately triumphant story of courageous struggle against mental illness will inspire anyone who has ever had to battle for achievement against overwhelming odds. After recovering from her illness, Carol returned to school and received her medical degree from Washington University School of Medicine in St. Louis, Missouri in 1983. She then completed her internship and residency at Barnes Hospital/Washington University, and subsequently obtained a masters degree in psychiatric epidemiology (the study of psychiatric disorders in populations) while simultaneously pursuing a NIMH fellowship in psychiatric epidemiology at Washington University. Dr. Carol North is currently a board-certified psychiatrist and full Professor of Psychiatry at Washington University School of Medicine. She treats patients with schizophrenia and a range of psychiatric illness, trains young physicians and psychiatrists, and pursues federally funded research in psychiatric epidemiology. She is the recipient of numerous national awards and has appeared on many national television and radio programs.

    Trading in her home for canvas roof and wheels, Mary, her husband, and their three children set out on the arduous trek westward to California.Shortly into their travels west, it became painfully obvious that Doctor Powers was simply not up to the task of making sure his family "outlasted the trail." Mary had to step in and become the head of the household with its canvas roof and wheels--leaving behind her ideals of femininity along with her beloved possessions.In Outlasting the Trail author Mary Barymeyer O'Brien uses the letters Mary Rockwood Powers wrote to her mother and sister back home as a stepping off point to further illuminate this remarkable woman's story. Based on the dramatic struggle a real family, this novel brings to life a fascinating slice of American history.

    We like to imagine that it’s based on evidence and the results of fair tests. In reality, those tests are often profoundly flawed. We like to imagine that doctors are familiar with the research literature surrounding a drug, when in reality much of the research is hidden from them by drug companies. We like to imagine that doctors are impartially educated, when in reality much of their education is funded by industry. We like to imagine that regulators let only effective drugs onto the market, when in reality they approve hopeless drugs, with data on side effects casually withheld from doctors and patients.All these problems have been protected from public scrutiny because they’re too complex to capture in a sound bite. But Dr. Ben Goldacre shows that the true scale of this murderous disaster fully reveals itself only when the details are untangled. He believes we should all be able to understand precisely how data manipulation works and how research misconduct on a global scale affects us. In his own words, “the tricks and distortions documented in these pages are beautiful, intricate, and fascinating in their details.” With Goldacre’s characteristic flair and a forensic attention to detail, Bad Pharma reveals a shockingly broken system and calls for something to be done. This is the pharmaceutical industry as it has never been seen before.

    In this wise and passionate book, one of our most eminent physicians reacquaints us with a classic notion often overlooked in modern medicine: health care with a human face, in which the time-honored art of healing guides doctors in their approach to patient care and their use of medical technology.Drawing on four decades of practice as a cardiologist and a vast knowledge of literature and medical history, Dr. Lown probes the heart and soul of the doctor-patient relationship. Insightful and accessible to all, The Lost Art of Healing describes how true healers use sympathetic listening and touch to hone their diagnostic skills, how language affects the perception of illness, how doctors and patients can cultivate a relationship of trust, and how patients can obtain the most complete and beneficial care through a combination of healing techniques and conventional practices. As Dr. Lown explains, the art of healing does not mean abandoning the spectacular advances of modern science, but rather incorporating them into a sensitive, humane, enlightened approach to medical care. With its urgent message and poignant, fascinating vignettes, The Lost Art of Healing is a book of vital, universal importance.

    She was a poor Southern tobacco farmer who worked the same land as her enslaved ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine. The first “immortal” human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, they’d weigh more than 50 million metric tons—as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions.Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave.Now Rebecca Skloot takes us on an extraordinary journey, from the “colored” ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henrietta’s small, dying hometown of Clover, Virginia — a land of wooden quarters for enslaved people, faith healings, and voodoo — to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells.Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family — past and present — is inextricably connected to the history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of.Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah, who was devastated to learn about her mother’s cells. She was consumed with questions: Had scientists cloned her mother? Did it hurt her when researchers infected her cells with viruses and shot them into space? What happened to her sister, Elsie, who died in a mental institution at the age of fifteen? And if her mother was so important to medicine, why couldn’t her children afford health insurance?Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.

    I was mentally and physically broken. So fractured, I hadn't eaten properly or slept well, or even changed my expression for months. I sat in a cubicle, behind paper-thin curtains, listening to the rest of the hospital happen around me, and I shook with the effort of not crying. I was an inch away from defeat, from the acceptance of a failure I assumed would be inevitable, but I knew I had to carry on. I had to somehow walk through it.Because I wasn't the patient. I was the doctor."A frank account of mental health from both sides of the doctor-patient divide, from the bestselling author of The Trouble with Goats and Sheep and Three Things About Elsie, based on her own experience as a doctor working on a psychiatric ward.

    This veteran television broadcaster and interviewer turns the camera on himself, taking the reader on an intimate journey. He moves beyond depression, tragedy, and self-doubt and grapples with his greatest decision: not simply whether to live but how to live. If you had only 24 hours left... what would you do?