After 3.8 billion years humankind is about to start evolving by new rules...From leading geopolitical expert and technology futurist Jamie Metzl comes a groundbreaking exploration of the many ways genetic-engineering is shaking the core foundations of our lives -- sex, war, love, and death.At the dawn of the genetics revolution, our DNA is becoming as readable, writable, and hackable as our information technology. But as humanity starts retooling our own genetic code, the choices we make today will be the difference between realizing breathtaking advances in human well-being and descending into a dangerous and potentially deadly genetic arms race.Enter the laboratories where scientists are turning science fiction into reality. Look towards a future where our deepest beliefs, morals, religions, and politics are challenged like never before and the very essence of what it means to be human is at play. When we can engineer our future children, massively extend our lifespans, build life from scratch, and recreate the plant and animal world, should we?

    Into this crisis stepped Walter Freeman, M.D., who saw a solution in lobotomy, a brain operation intended to reduce the severity of psychotic symptoms. Drawing on Freeman’s documents and interviews with Freeman's family, Jack El-Hai takes a penetrating look at the life and work of this complex scientific genius.The Lobotomist explores one of the darkest chapters of American medicine: the desperate attempt to treat the hundreds of thousands of psychiatric patients in need of help during the middle decades of the twentieth century. Into this crisis stepped Walter Freeman, M.D., who saw a solution in lobotomy, a brain operation intended to reduce the severity of psychotic symptoms. Although many patients did not benefit from the thousands of lobotomies Freeman performed, others believed their lobotomies changed them for the better. Drawing on a rich collection of documents Freeman left behind and interviews with Freeman's family, Jack El-Hai takes a penetrating look into the life of this complex scientific genius and traces the physician's fascinating life and work.

    From the research biologist who stung himself with every conceivable insect to the world's most murderous mammals, this book explores oft-ignored but alluring facets of biology, anatomy, space exploration, nature, and more. Featuring interviews with leading researchers in the field and a large dose of wit, the author reveals the most intriguing real-world applications of science in all their glory.

    As conscientious objectors during World War II, these men were eager to help in the war effort but restricted from combat by their pacifist beliefs. So, instead, they volunteered to become guinea pigs in one of the most unusual experiments in medical history -- one that required a year of systematic starvation. Dr. Ancel Keys was already famous for inventing the K ration when the War Department asked for his help with feeding the starving citizens of Europe and the Far East at the war's end. Fascists and Communists, it was feared, could gain a foothold in war-ravaged areas. "Starved people," Keys liked to say, "can't be taught Democracy." The government needed to know the best way to rehabilitate those people who had been severely underfed during the long war. To study rehabilitation, Keys first needed to create a pool of starving test subjects. Gathered in a cutting-edge lab underneath the football stadium at the University of Minnesota, Dr. Keys' test subjects forsook most food and were monitored constantly so that Dr. Keys and his scientists could study the effects of starvation on otherwise healthy people. While the weight loss of the men followed a neat mathematical curve, the psychological deterioration was less predictable. Some men drank quarts and quarts of water to fill their empty stomachs. One man chewed as many as forty packs of gum a day. One man mutilated himself to escape the experiment. Ultimately only four of the men were expelled from the experiment for cheating -- a testament to the volunteers' determination and toughness. To prevent atrocities of the kind committed by the Nazi doctors, international law now prevents this kind of experimentation on healthy people. But in this remarkable book, Todd Tucker captures a lost sliver of American history -- a time when cold scientific principles collided with living, breathing human beings. Tucker depicts the agony and endurance of a group of extraordinary men whose lives were altered not only for the year they participated in the experiment, but forever.

    In her long and varied life, she was to travel in Central America, Russia and Europe, find work as a inn-keeper and as a doctress during the Crimean War, and become a famed heroine, the author of her own biography, in Britain. As this autobiography shows, Mary Seacole had a sharp instinct for hypocrisy as well as a ripe taste for sarcasm. Frequently we see her joyfully rise to mock the limitations artificially imposed on her as a black woman. She emerges from her writings as an individual with a most un-Victorian zest for travel, adventure and independence.

    Joel Salinas is a Harvard-trained researcher and neurologist with extraordinary gifts that provide him unique access to his patients and enable him to experience life in an extraordinary way. He has mirror-touch synesthesia, a neurological trait that allows him to feel others’ emotions and physical sensations. Susceptible to the pain and discomfort of his patients—most of whom suffer from strokes, spinal cord injuries, multiple sclerosis, and a host of other painful disorders and extreme injuries—Salinas uses his heightened emphatic ability—what he calls "compulsory mindfulness"—to help understand and better treat their conditions.Using his own experiences as a neurologist and synesthete as a narrative through line, Salinas also shares the remarkable stories of equally remarkable subjects who similarly live in a heightened state of awareness, whether because of a congenital condition, after a seemingly debilitating stroke, or amidst an ecstatic seizure.Written with intelligence and compassion, and anchored by the latest developments in neurology, psychology and psychiatry, Mirror Touch is an enthralling investigation into the power of the brain—one that proves that the mind, in wondrous and mysterious fashion, continues to promise exciting and inexhaustible ways to think, to see, and to be.

    For every one of the cells that make up the vessel that you call your body, there are nine impostor cells hitching a ride. You are not just flesh and blood, muscle and bone, brain and skin, but also bacteria and fungi. Over your lifetime, you will carry the equivalent weight of five African elephants in microbes. You are not an individual but a colony.Until recently, we had thought our microbes hardly mattered, but science is revealing a different story, one in which microbes run our bodies and becoming a healthy human is impossible without them.In this riveting, shocking, and beautifully written book, biologist Alanna Collen draws on the latest scientific research to show how our personal colony of microbes influences our weight, our immune system, our mental health, and even our choice of partner. She argues that so many of our modern diseases—obesity, autism, mental illness, digestive disorders, allergies, autoimmunity afflictions, and even cancer—have their root in our failure to cherish our most fundamental and enduring relationship: that with our personal colony of microbes.Many of the questions about modern diseases left unanswered by the Human Genome Project are illuminated by this new science. And the good news is that unlike our human cells, we can change our microbes for the better. Collen's book is a revelatory and indispensable guide. It is science writing at its most relevant: life—and your body—will never seem the same again.

    With wisdom, humor, and scientific aplomb, medical students and sex educators Nina Brochmann and Ellen Støkken Dahl take readers on a fascinating journey of female sexual organs and sexual health--from the clitoris to contraception to cervical cancer.More than a user's manual, this book is demystification, and tribute to the vagina that we have been waiting for. The Wonder Down Under is filled with astonishing, important, and little-known information--relayed with both medical expertise and genuine empathy. Did you know, for instance, that female and male sex organs are merely variations on the same basic structure? Or that there's no such thing as a virginity test--because a broken hymen is not a meaningful indicator of whether or not someone's had sex?Brochmann and Dahl have written a tour-de-force about the biology, anatomy, and reality of the female body, stopping along the way to explain how misinformation and silence about the vagina have been harmful to women over time. The Wonder Down Under makes crucial contributions to the discussion: the book was an instant bestseller that sold out in its native Norway in just three days. Since then it has been acquired by publishers in more than two dozen countries around the world.The Wonder Down Under is a joyful and indispensable book that will educate readers of all kinds and equip a new generation to make informed choices about their sexual health and happiness.

    Written in the same offbeat, "lecture-style" you're familiar with, the second edition provides a perfect introduction to the essential principles of the immune system, covered in 9 humorous but highly informative "lectures." Perfect as exam-prep review or an enjoyable overview of a difficult subject. This revised edition features: - New updates on the Pathophysiology of immunology - System-based approach that examines immunology as a system - Unique and engaging style for quick and easy learning

    Ironically, the "discovery" was really no discovery at all: Ether and nitrous oxide had been known for more than forty years to cause insensitivity to pain, yet, with names like "laughing gas," they were used almost solely for entertainment. Meanwhile, patients still underwent operations during which they saw, heard, and felt every cut the surgeon made. The image of a grim and grisly operating room, like the one in Mary Shelley's Frankenstein, was in fact starkly accurate in portraying the conditions of surgery before anesthesia.With hope for relief seemingly long gone, the breakthrough finally came about by means of a combination of coincidence and character, as a cunning Boston dentist crossed paths with an inventive colleague from Hartford and a brilliant Harvard-trained physician. William Morton, Horace Wells, and Charles Jackson: a con man, a dreamer, and an intellectual. Though Wells was crushed by derision when he tried to introduce anesthetics, Morton prevailed, with help from Jackson. The result was Ether Day, October 16, 1846, celebrated around the world. By that point, though, no honor was enough. Ether Day was not only the dawn of modern surgery, but the beginning of commercialized medicine as well, as Morton patented the discovery.What followed was a battle so bitter that it sent all three men spiraling wildly out of control, at the same time that anesthetics began saving countless lives. Meticulously researched and masterfully written, Ether Day is a riveting look at one of history's most remarkable untold stories.

    From "good vibes only" and "life is good" memes, to endless advice, to "look on the bright side," we're constantly told that the key to happiness is silencing negativity wherever it crops up, in ourselves and in others. Even when faced with illness, loss, breakups, and other challenges, there's little space for talking about our real feelings--and processing them so that we can feel better and move forward.But if all this positivity is the answer, why are so many of us anxious, depressed, and burned out?In this refreshingly honest guide, sought-after therapist Whitney Goodman shares the latest research along with everyday examples and client stories that reveal how damaging toxic positivity is to ourselves and our relationships, and presents simple ways to experience and work through difficult emotions. The result is more authenticity, connection, and growth--and ultimately, a path to showing up as you truly are.

    In the era of Donald Trump, many lower- and middle-class white Americans are drawn to politicians who pledge to make their lives great again. But as Dying of Whiteness shows, the policies that result actually place white Americans at ever-greater risk of sickness and death.Physician Jonathan M. Metzl's quest to understand the health implications of "backlash governance" leads him across America's heartland. Interviewing a range of everyday Americans, he examines how racial resentment has fueled pro-gun laws in Missouri, resistance to the Affordable Care Act in Tennessee, and cuts to schools and social services in Kansas. And he shows these policies' costs: increasing deaths by gun suicide, rising dropout rates, and falling life expectancies. White Americans, Metzl argues, must reject the racial hierarchies that promise to aid them but in fact lead our nation to demise.

    What would you see if you removed the skull from the human brain and then slowly worked your way deeper and deeper into the brain, to the level of an individual neuron? With renowned brain researcher Susan Greenfield as your guide, here is your chance to gain a bird's eye view of the human brain—and to learn more about what the brain is, how it works, what happens when one part of the brain is made dysfunctional through stroke or accident, how brain mood-modifying drugs find their targets.In a particularly fascinating chapter, Greenfield surveys for us how a brain is built and then takes us on a tour of the developing brain from the moment of conception.Throughout Greenfield poses the larger questions all readers want to consider, including: At what stage does individuality creep into the developing brain? How does the collection of circuits of neurons give rise not just to an individual brain but an individual consciousness? What might a fetus be conscious of?

    You'll experience the rush of adrenaline and the pain of loss. You'll go beyond the lights and sirens to witness the instinct of intelligence, the courage and commitment that makes the EMT an unsung hero in one of the most vital and compelling medical dramas of our time.

    If they do it right, they will have a good chance of putting an end to Neil's seizures. If they slice too far to the left or right, they will wipe out essential parts of Neil's memory, or his ability to follow a joke to the punch line, or maybe his ability to recognize his wife's face. In essence, they can erase or alter parts of Neil.Conversations with Neil's Brain takes us inside the operating room and allows us to be part of this eerie process of discovery, using it to provide a unique window on human consciousness and the nature of human identity. The mapping of Neil's brain brings to life as never before the astounding specificity by which the brian operates, making clear why language, memory, and decision making are so complex, and why the cures for such ailments as learning disabilities, mental disorders, Alzheimer's, and strokes continue to elude the world's best medical efforts. In the context of this unique surgical drama, Conversations with Neil's Brain unfolds as an intensely compelling read.