In my case, blinking my left eyelid is my only means of communication.’In December 1995, Jean-Dominique Bauby, editor-in-chief of French ‘Elle’ and the father of two young children, suffered a massive stroke and found himself paralysed and speechless, but entirely conscious, trapped by what doctors call ‘locked-in syndrome’. Using his only functioning muscle – his left eyelid – he began dictating this remarkable story, painstakingly spelling it out letter by letter.His book offers a haunting, harrowing look inside the cruel prison of locked-in syndrome, but it is also a triumph of the human spirit.

    Styron is perhaps the first writer to convey the full terror of depression's psychic landscape, as well as the illuminating path to recovery.

    Even as a reporter, Sheila Hamilton missed the signs as her husband David's mental illness unfolded before her. By the time she had pieced together the puzzle, it was too late. Her once brilliant and passionate partner was dead within six weeks of a diagnosis of bipolar disorder, leaving his wife and nine-year-old daughter without so much as a note to explain his actions, a plan to help them recover from their profound grief, or a solution for the hundreds of thousands of dollars in debt that they would inherit from him.All the Things We Never Knew takes readers on a breathtaking journey, from David and Sheila's early romance through the last three months of their life together and into the year after his death. It details their unsettling spiral from ordinary life into the world of mental illness, examines the fragile line between reality and madness, and reveals the true power of love and forgiveness.

    During that year of physical recovery, Runyon began to question what he’d done, undertaking the complicated journey from near-death back to high school, and from suicide back to the emotional mainstream of life.In the tradition of Running with Scissors and Girl, Interrupted, The Burn Journals is a truly remarkable book about teenage despair and recovery.

    No food for ten. And a ward full of soon-to-be mothers… Welcome to the life of a midwife. Life on the NHS front line, working within a system at breaking point, is more extreme than you could ever imagine. From the bloody to the beautiful, from moments of utter vulnerability to remarkable displays of strength, from camaraderie to raw desperation, from heart-wrenching grief to the pure, perfect joy of a new-born baby, midwife Leah Hazard has seen it all.Through her eyes, we meet Eleanor, whose wife is a walking miracle of modern medicine, their baby a feat of reproductive science; Crystal, pregnant at just fifteen, the precarious, flickering life within her threatening to come far too soon; Star, birthing in a room heady with essential oils and love until an enemy intrudes and Pei Hsuan, who has carried her tale of exploitation and endurance thousands of miles to somehow find herself at the open door of Leah’s ward.Moving, compassionate and intensely candid, Hard Pushed is a love letter to new mothers and to Leah’s fellow midwives – there for us at some of the most challenging, empowering and defining moments of our lives.

    A NATURAL WOMAN chronicles King's extraordinary life, drawing readers into her musical world, including her phenomenally successful #1 album Tapestry, and into her journey as a performer, mother, wife and present-day activist. Deeply personal, King's long-awaited memoir offers readers a front-row seat to the woman behind the legend. The book will include dozens of photos from King's childhood, her own family, and behind-the-scenes images from her performances.

    As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned ​a curiosity ​of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020.

    Our stories are marbled into their marrow.Drawing upon her years of research and a wealth of remarkable experience, the world-renowned forensic anthropologist Professor Dame Sue Black takes us on a journey of revelation. From skull to feet, via the face, spine, chest, arms, hands, pelvis and legs, she shows that each part of us has a tale to tell. What we eat, where we go, everything we do leaves a trace, a message that waits patiently for months, years, sometimes centuries, until a forensic anthropologist is called upon to decipher it.Some of this information is easily understood, some holds its secrets tight and needs scientific cajoling to be released. But by carefully piecing together the evidence, the facts of a life can be rebuilt. Limb by limb, case by case – some criminal, some historical, some unaccountably bizarre – Sue Black reconstructs with intimate sensitivity and compassion the hidden stories in what we leave behind.

    She was a poor Southern tobacco farmer who worked the same land as her enslaved ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine. The first “immortal” human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, they’d weigh more than 50 million metric tons—as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions.Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave.Now Rebecca Skloot takes us on an extraordinary journey, from the “colored” ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henrietta’s small, dying hometown of Clover, Virginia — a land of wooden quarters for enslaved people, faith healings, and voodoo — to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells.Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family — past and present — is inextricably connected to the history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of.Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah, who was devastated to learn about her mother’s cells. She was consumed with questions: Had scientists cloned her mother? Did it hurt her when researchers infected her cells with viruses and shot them into space? What happened to her sister, Elsie, who died in a mental institution at the age of fifteen? And if her mother was so important to medicine, why couldn’t her children afford health insurance?Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.

    She had killed someone with a thought, spread untold disease, and ogled the bodies of other children. Only by performing an exhausting series of secret routines could she make up for what she’d done. But no matter how intricate or repetitive, no act of penance was ever enough.Beautifully written and astonishingly intimate, Because We Are Bad recounts a childhood consumed by obsessive compulsive disorder. As a child, Bailey created a second personality inside herself—"I" became "we"—to help manifest compulsions that drove every minute of every day of her young life. Now she writes about the forces beneath her skin, and how they ordered, organized, and urged her forward. Lily charts her journey, from checking on her younger sister dozens of times a night, to "normalizing" herself at school among new friends as she grew older, and finally to her young adult years, learning—indeed, breaking through—to make a way for herself in a big, wide world that refuses to stay in check.Charming and raw, harrowing and redemptive, Because We Are Bad is an illuminating and uplifting look into the mind and soul of an extraordinary young woman, and a startling portrait of OCD that allows us to see and understand this condition as never before.

    She witnesses nurses drawing straws to see who would tend to the patient inside, all of them reluctant to enter the room. Out of impulse, Ruth herself enters the quarantined space and immediately begins to care for the young man who cries for his mother in the last moments of his life. Before she can even process what she's done, word spreads in the community that Ruth is the only person willing to help these young men afflicted by AIDS, and is called upon to nurse them. As she forges deep friendships with the men she helps, she works tirelessly to find them housing and jobs, even searching for funeral homes willing to take their bodies - often in the middle of the night. She cooks meals for tens of people out of discarded food found in the dumpsters behind supermarkets, stores rare medications for her most urgent patients, teaches sex-ed to drag queens after hours at secret bars, and becomes a beacon of hope to an otherwise spurned group of ailing gay men on the fringes of a deeply conservative state.Throughout the years, Ruth defies local pastors and nurses to help the men she cares for: Paul and Billy, Angel, Chip, Todd and Luke. Emboldened by the weight of their collective pain, she fervently advocates for their safety and visibility, ultimately advising Governor Bill Clinton on the national HIV-AIDS crisis.This deeply moving and elegiac memoir honors the extraordinary life of Ruth Coker Burks and the beloved men who fought valiantly for their lives with AIDS during a most hostile and misinformed time in America.

    Six years later she made her first suicide attempt, then wandered the streets of New York City dressed in ragged clothes, tormenting voices crying out in her mind. Lori Schiller had entered the horrifying world of full-blown schizophrenia. She began an ordeal of hospitalizations, halfway houses, relapses, more suicide attempts, and constant, withering despair. But against all odds, she survived. Now in this personal account, she tells how she did it, taking us not only into her own shattered world, but drawing on the words of the doctors who treated her and family members who suffered with her.In this new edition, Lori Schiller recounts the dramatic years following the original publication -- a period involving addiction, relapse, and ultimately, love and recovery.Moving, harrowing, and ultimately uplifting, THE QUIET ROOM is a classic testimony to the ravages of mental illness and the power of perseverance and courage.

    Only one has told her story.three years after giving up alcohol, Jowita Bydlowska found herself throwing back a glass of champagne like it was lemonade. 'It's a special occasion,' she said to her boyfriend. And indeed it was. It was a party celebrating the birth of their first child. It also marked Jowita's immediate, full-blown return to alcoholism and all that entails for a new mother who is at first determined to keep her problem a secret. Her trips to bottle shops stores are in-and-out missions. Perhaps she's being paranoid, but she thinks people tend to notice the stroller. Walking home, she stays behind buildings, in alleyways, taking discreet sips from a bottle she's stored in the nappy bag. She know she's become a villain: a mother who drinks; a mother who endangers her child. She drinks to forget this. And then the trouble really starts. Jowita Bydlowska's memoir of her relapse into addiction is an extraordinary achievement. the writing is raw and immediate. It places you in the moment - saddened and appalled but never able to look away. With brutal honesty, DRUNK MUM takes us through the binges and blackouts, the self-deception and less successful attempts to deceive others, the humiliations and extraordinary risk-taking. She shines a light on the endless hunger of wanting just one more drink, and one more again, while dealing with motherhood, anxiety, depression - and rehab. Advance Praise for Drunk Mom: 'Jowita is matter of fact, funny, fearless, and irreverent as she lifts the veil to chronicle what it means to be a young mother when both baby and mother have their own bottles - the shame and the inner voices, as well as the joy and relief. this book is for anyone who has ever struggled to make it through a day.' - Laura Albert, a.k.a. Jt LeRoy, author of Sarah, the Heart Is Deceitful Above All things and Harold's End 'Drunk Mom is a stunning, harrowing read. Why harrowing? Not just because of the dramatic story, of a new mother at the edge of her tether. And not only because of Jowita Bydlowska's skill as a writer, and the crisp, original way she tells it. What's most harrowing about Drunk Mom is that you can't stop reading it-this, the dark, now-told tale that lurks in the shadow of every seemingly normal family.' - Ian Brown, author of the Boy in the Moon 'A brave, brilliant and scathing self-portrait. Full of energy and insight. If Frida Kahlo had been a writer, she might have been compared to Jowita Bydlowska.' - Patricia Pearson, author of A Brief History of Anxiety - Yours and Mine. 'Fearless and troubling, and so very humane, Bydlowska explodes the cutesy momoir genre. You'll read it in one sitting.' - Katrina Onstad, author of Everybody Has Everything.

    She had fallen in love and moved to Paris to pursue her dream of becoming a war correspondent. The real world she found, however, would take her into a very different kind of conflict zone.It started with an itch—first on her feet, then up her legs, like a thousand invisible mosquito bites. Next came the exhaustion, and the six-hour naps that only deepened her fatigue. Then a trip to the doctor and, a few weeks shy of her twenty-third birthday, a diagnosis: leukemia, with a 35 percent chance of survival. Just like that, the life she had imagined for herself had gone up in flames. By the time Jaouad flew home to New York, she had lost her job, her apartment, and her independence. She would spend much of the next four years in a hospital bed, fighting for her life and chronicling the saga in a column for The New York Times.When Jaouad finally walked out of the cancer ward—after three and a half years of chemo, a clinical trial, and a bone marrow transplant—she was, according to the doctors, cured. But as she would soon learn, a cure is not where the work of healing ends; it’s where it begins. She had spent the past 1,500 days in desperate pursuit of one goal—to survive. And now that she’d done so, she realized that she had no idea how to live.How would she reenter the world and live again? How could she reclaim what had been lost? Jaouad embarked—with her new best friend, Oscar, a scruffy terrier mutt—on a 100-day, 15,000-mile road trip across the country. She set out to meet some of the strangers who had written to her during her years in the hospital: a teenage girl in Florida also recovering from cancer; a teacher in California grieving the death of her son; a death-row inmate in Texas who’d spent his own years confined to a room. What she learned on this trip is that the divide between sick and well is porous, that the vast majority of us will travel back and forth between these realms throughout our lives. Between Two Kingdoms is a profound chronicle of survivorship and a fierce, tender, and inspiring exploration of what it means to begin again.

    In her first foray into nonfiction, she takes the raw stuff of her personal life and spins into a collection of essays on modern womanhood as uproariously funny and moving as the best of Tina Fey, Fran Lebowitz, and Nora Ephron.Jennifer grew up as an outsider in her picturesque Connecticut hometown (“a Lane Bryant outtake in an Abercrombie & Fitch photo shoot”) and at her Ivy League college, but finally found her people in newsrooms in central Pennsylvania and Philadelphia, and her voice as a novelist, activist, and New York Times columnist.No subject is off-limits in this intimate and honest essay collection: sex, weight, envy, money, her mom’s newfound lesbianism, and her estranged father’s death. From lonely adolescence to modern childbirth to hearing her six-year-old daughter’s use of the f-word—fat­­—for the first time, Jennifer Weiner goes there, with the wit and candor that have endeared her to readers all over the world.By turns hilarious and deeply touching, this collection shows that the woman behind treasured novels like Good in Bed and Best Friends Forever is every bit as winning, smart, and honest in real life as she is in her fiction.