But things didn't turn out that way. For a start, we turned out to have far fewer genes than originally thought - just over 20,000, the same sort of number as a fruit fly or worm. What's more, the proportionof DNA consisting of genes coding for proteins was a mere 2%. So, was the rest of the genome accumulated 'junk'?Things have changed since those early heady days of the Human Genome Project. But the emerging picture is if anything far more exciting. In this book, John Parrington explains the key features that are coming to light - some, such as the results of the international ENCODE programme, still much debated and controversial in their scope. He gives an outline of the deeper genome, involving layers of regulatory elements controlling and coordinating the switching on and off of genes; the impact ofits 3D geometry; the discovery of a variety of new RNAs playing critical roles; the epigenetic changes influenced by the environment and life experiences that can make identical twins different and be passed on to the next generation; and the clues coming out of comparisons with the genomes ofNeanderthals as well as that of chimps about the development our species. We are learning more about ourselves, and about the genetic aspects of many diseases. But in its complexity, flexibility, and ability to respond to environmental cues, the human genome is proving to be far more subtle than we ever imagined.

    The word conjures up images of horrific diseases sweeping the globe and killing everyone in their path. But such highly lethal illnesses almost never create pandemics. The reality is deadly serious but far more subtle.In Pandemics: What Everyone Needs to Know�, Peter Doherty, who won the Nobel Prize for his work on how the immune system recognizes virus-infected cells, offers an essential guide to one of the truly life-or-death issues of our age. In concise, question-and-answer format, he explains the causes of pandemics, how they can be counteracted with vaccines and drugs, and how we can better prepare for them in the future. Doherty notes that the term "pandemic" refers not to a disease's severity but to its ability to spread rapidly over a wide geographical area. Extremely lethal pathogens are usually quickly identified and confined. Nevertheless, the rise of high-speed transportation networks and the globalization of trade and travel have radically accelerated the spread of diseases. A traveler from Africa arrived in New York in 1999 carrying the West Nile virus; one mosquito bite later, it was loose in the ecosystem. Doherty explains how the main threat of a pandemic comes from respiratory viruses, such as influenza and SARS, which disseminate with incredible speed through air travel. The climate disruptions of global warming, rising population density, and growing antibiotic resistance all complicate efforts to control pandemics. But Doherty stresses that pandemics can be fought effectively. Often simple health practices, especially in hospitals, can help enormously. And research into the animal reservoirs of pathogens, from SARS in bats to HIV in chimpanzees, show promise for our prevention efforts.Calm, clear, and authoritative, Peter Doherty's Pandemics is one of the most critically important additions to the What Everyone Needs to Know� series.What Everyone Needs to Know� is a registered trademark of Oxford University Press.

    This book is a provocative yet balanced work that addresses a wide range of topics, from the value of human life to sexual mortality, to racial extermination.

    Its contributors—some of the most brilliant young scientists working today—provide not only an introduction to their cutting-edge research, but discuss the social, ethical, and philosophical ramifications of their work. With essays covering fields as diverse as astrophysics, paleoanthropology, climatology, and neuroscience, What's Next? is a lucid and informed guide to the new frontiers of science.

    The text, under the editorship of Stephen Jay Gould, provides a thorough understanding of the latest research and is accompanied by paintings prepared especially for this book. Never before has our planet's evolution been so clearly, so ingeniously explained. History is marked by disaster. The Book of Lifeexplains how mammals, having survived at least one of these disasters—the impact of a massive comet—luckily inherited the earth. Next came the rise of modern humans, who would shape the world as no creature has. As this fascinating history unfolds, gorgeous illustrations allow us to observe climate changes, tectonic plate movement, the spread of plant life, and the death of the dinosaurs. We discover the chains of animal survival, the causes and consequences of adaptation, and finally the environmental impact of human life.

    Its full-colour illustration program includes many novel, visually effective features to help students learn.

    Richard Dawkins, for example, jolted us into realizing that we are just survival mechanisms for our own genes, sophisticated robots in service of huge colonies of replicators to whom concepts of rationality, intelligence, agency, and even the human soul are irrelevant.Accepting and now forcefully responding to this decentering and disturbing idea, Keith Stanovich here provides the tools for the "robot's rebellion," a program of cognitive reform necessary to advance human interests over the limited interest of the replicators and define our own autonomous goals as individual human beings. He shows how concepts of rational thinking from cognitive science interact with the logic of evolution to create opportunities for humans to structure their behavior to serve their own ends. These evaluative activities of the brain, he argues, fulfill the need that we have to ascribe significance to human life. We may well be robots, but we are the only robots who have discovered that fact. Only by recognizing ourselves as such, argues Stanovich, can we begin to construct a concept of self based on what is truly singular about humans: that they gain control of their lives in a way unique among life forms on Earth—through rational self-determination.

    and a Professor of Life Sciences at UCLA who is immersed in the debate on religion. In Anarchy Evolution, Graffin puts forth his bold ideas about “naturalism” and the connection between science religion and art. In this provocative and timely book, Graffin tackles head on the “intellectual dishonestly” of creationism; he also shares compelling stories about his childhood and how science saved him when he ran into trouble as a teenager. Anarchy Evolution will appeal to the fans of Bad Religion (which as sold over 2.8 million albums) as well as readers of Richard Dawkins and Christopher Hitchens. The book coincides with a major national Bad Religion reunion tour that will start in October of 2010.

    Gitt maintains that God is not bound by the laws of nature, but instead uses them for His own purposes.

    A highly regarded scientist’s examination of the battle between evolution and intelligent design, and its implications for how science is practiced in America.

    Pulitzer Prize–winning author Siddhartha Mukherjee, a leading cancer physician and researcher, selects the year’s top science and nature writing from journalists who dive into their fields with curiosity and passion, delivering must-read articles from a wide array of fields.

    To understand the universe in the far future, we must first describe its present state and structure on the grand scale, and how its present properties arose. Dr Islam explains these topics in an accessible way in the first part of the book. From this background he speculates about the future evolution of the universe and predicts the major changes that will occur. The author has largely avoided mathematical formalism and therefore the book is well suited to general readers with a modest background knowledge of physics and astronomy.

    It says what most scientists and politicians are afraid to say about what research can and, perhaps more importantly, cannot deliver on topics ranging from sexuality, race and genetic modification to stem cells, cloning, modern medicine, fertility treatment, creationism and bioterrorism.Having worked at the heart of government science, at the most prestigious science publishing company in the world, and in one of the world's leading biology institutions the author has a unique view of the politics, culture and reach of science. He illustrates how we are facing dangerous times where political agendas and public misunderstanding are hobbling truly novel work and hence calls for wide reaching changes in science education, funding, publishing and promulgation.

    This is a book about how many of the 'big' philosophical and religious questions that have puzzled mankind for centuries can be answered by recent breakthroughs in science.

    Keith Mathison tackles a topic that has long been a subject of debate, aiming to enable believers to approach questions pertaining to science and Scripture with grace, humility, and patience.