But nowhere is this drive to do better more important than in medicine, where lives are on the line with every decision. In his new book, Atul Gawande explores how doctors strive to close the gap between best intentions and best performance in the face of obstacles that sometimes seem insurmountable. Gawande's gripping stories of diligence, ingenuity, and what it means to do right by people take us to battlefield surgical tents in Iraq, to labor and delivery rooms in Boston, to a polio outbreak in India, and to malpractice courtrooms around the country. He discusses the ethical dilemmas of doctors participation in lethal injections, examines the influence of money on modern medicine, and recounts the astoundingly contentious history of hand washing. And as in all his writing, Gawande gives us an inside look at his own life as a practicing surgeon, offering a searingly honest firsthand account of work in a field where mistakes are both unavoidable and unthinkable. At once unflinching and compassionate, Better is an exhilarating journey narrated by arguably the best nonfiction doctor-writer around (Salon). Gawande's investigation into medical professionals and how they progress from merely good to great provides rare insight into the elements of success, illuminating every area of human endeavor.

    Mixing memoir with mendacity, Slater examines memories of her youth, when after being diagnosed with a strange illness she developed seizures and neurological disturbances—and the compulsion to lie. Openly questioning the reliability of memoir itself, Slater presents the mesmerizing story of a young woman who discovers not only what plagues her but also what cures her—the birth of her sensuality, her creativity as an artist, and storytelling as an act of healing.

    What propels this chronicle of her recovery is Sebold's indomitable spirit - as she struggles for understanding ("After telling the hard facts to anyone, from lover to friend, I have changed in their eyes"); as her dazed family and friends sometimes bungle their efforts to provide comfort and support; and as, ultimately, she triumphs, managing through grit and coincidence to help secure her attacker's arrest and conviction. In a narrative by turns disturbing, thrilling, and inspiring, Alice Sebold illuminates the experience of trauma victims even as she imparts wisdom profoundly hard-won: "You save yourself or you remain unsaved."

    It is a poignant observation about the relationship between Mira, her sister, and their mentally ill mother. Before she was struck with schizophrenia at the age of nineteen, beautiful piano protégé Norma Herr had been the most vibrant personality in the room. She loved her daughters and did her best to raise them well, but as her mental state deteriorated, Norma spoke less about Chopin and more about Nazis and her fear that her daughters would be kidnapped, murdered, or raped. When the girls left for college, the harassment escalated--Norma called them obsessively, appeared at their apartments or jobs, threatened to kill herself if they did not return home. After a traumatic encounter, Mira and her sister were left with no choice but to change their names and sever all contact with Norma in order to stay safe. But while Mira pursued her career as an artist--exploring the ancient romance of Florence, the eerie mysticism of northern Norway, and the raw desert of Israel--the haunting memories of her mother were never far away. Then one day, Mira’s life changed forever after a debilitating car accident. As she struggled to recover from a traumatic brain injury, she was confronted with a need to recontextualize her life--she had to relearn how to paint, read, and interact with the outside world. In her search for a way back to her lost self, Mira reached out to the homeless shelter where she believed her mother was living and discovered that Norma was dying. Mira and her sister traveled to Cleveland, where they shared an extraordinary reconciliation with their mother that none of them had thought possible. At the hospital, Mira discovered a set of keys that opened a storage unit Norma had been keeping for seventeen years. Filled with family photos, childhood toys, and ephemera from Norma’s life, the storage unit brought back a flood of previous memories that Mira had thought were lost to her forever. The Memory Palace is a breathtaking literary memoir about the complex meaning of love, truth, and the capacity for forgiveness among family. Through stunning prose and original art created by the author in tandem with the text, The Memory Palace explores the connections between mother and daughter that cannot be broken no matter how much exists--or is lost--between them.

    She believes that by shedding our armor, we can stop hiding, competing, striving for the mirage of perfection, and making motherhood, marriage, and friendship harder by pretending they’re not hard. In this one woman trying to love herself and others, readers find a wise and witty friend who will inspire them to forgive their own imperfections, make the most of their gifts, and commit to small acts of love that will change the world.

    At age thirteen, he is mentally and developmentally between one and three years old and will need constant care for the rest of his life. Brown travels the globe, meeting with genetic scientists and neurologists as well as parents, to solve the questions Walker’s doctors can’t answer. In his journey, he offers an insightful critique of society’s assumptions about the disabled, and he discovers a connected community of families living with this illness. As Brown gradually lets go of his self-blame and hope for a cure, he learns to accept the Walker he loves, just as he is. Honest, intelligent, and deeply moving, The Boy in the Moon explores the value of a single human life.

    This New York Times bestselling memoir of a young man’s addiction to methamphetamine tells a raw, harrowing, and ultimately hopeful tale of the road from relapse to recovery.Nic Sheff was drunk for the first time at age eleven. In the years that followed, he would regularly smoke pot, do cocaine and Ecstasy, and develop addictions to crystal meth and heroin. Even so, he felt like he would always be able to quit and put his life together whenever he needed to. It took a violent relapse one summer in California to convince him otherwise. In a voice that is raw and honest, Nic spares no detail in telling us the compelling, heartbreaking, and true story of his relapse and the road to recovery. As we watch Nic plunge into the mental and physical depths of drug addiction, he paints a picture for us of a person at odds with his past, with his family, with his substances, and with himself. It's a harrowing portrait—but not one without hope.

    These beautifully rendered tales illuminate the fundamental pathways of life from birth to death.A woman finds herself daydreaming as she returns home from a business trip; a young man loses his wallet. We learn, too, from more extreme examples: the patient who points an unloaded gun at a police officer, the compulsive liar who convinces his wife he's dying of cancer. The stories invite compassionate understanding, suggesting answers to the questions that compel and disturb us most about love and loss, parents and children, work and change. The resulting journey will spark new ideas about who we are and why we do what we do.

     A Million Little Pieces was the first Oprah Book Club pick by a living author in over two years. It instantly became a #1 New York Times bestseller, a #1 USA Today bestseller, and a #1 Publishers Weekly bestseller, with over 1.7 million copies in print. My Friend Leonard picks up right where Pieces leaves off. A New York Times bestseller in its own right before the Oprah pick, My Friend Leonard is James Frey's story of his friendship with Leonard, the larger-than-life mobster who "adopted" James as he left rehab. Leonard, who offers James lucrative-if illegal, mysterious, and slightly dangerous-employment when he needs it. Leonard, of the secret deals, of the surprising passions that belie his violent career choice, of fantastic generosity and ferocious loyalty. Leonard, who has been holding on to some remarkable secrets, and who has invested in their friendship more than James could ever imagine. My Friend Leonard is, at its core, about the responsibility that comes with loving someone and going out on any number of limbs to care for them. And it is a book that proves that one of the most provocative literary voices of his generation is also one of the most emphatically human.

    But he was alive and trapped inside his own body for ten years.In January 1988 Martin Pistorius, aged twelve, fell inexplicably sick. First he lost his voice and stopped eating. Then he slept constantly and shunned human contact. Doctors were mystified. Within eighteen months he was mute and wheelchair-bound. Martin's parents were told an unknown degenerative disease left him with the mind of a baby and less than two years to live.Martin was moved to care centers for severely disabled children. The stress and heartache shook his parents’ marriage and their family to the core. Their boy was gone. Or so they thought.Ghost Boy is the heart-wrenching story of one boy’s return to life through the power of love and faith. In these pages, readers see a parent’s resilience, the consequences of misdiagnosis, abuse at the hands of cruel caretakers, and the unthinkable duration of Martin’s mental alertness betrayed by his lifeless body.We also see a life reclaimed—a business created, a new love kindled—all from a wheelchair. Martin's emergence from his own darkness invites us to celebrate our own lives and fight for a better life for others.

    Although labeled, at times, deaf, retarded, or disturbed, Donna Williams is autistic--afflicted by a baffling condition of heightened sensory perception that imprisons the sufferer in a private, almost hallucinatory universe of patterns and colors. Nobody Nowhere is Donna's story in her own words--a haunting, courageous memoir of the titanic struggles she has endured in her quest to merge "my world" with "the world."

    Her journey there began when, overwhelmed by anxiety as she completed her doctoral studies in London, England, she found relief by dosing herself with alcohol and tranquillizers. She then embarked on what would turn out to be a decades- long psychoanalysis.The analysis dredged up acutely painful memories of an unhappy and confusing childhood back in Saskatoon. As Taylor struggled to cope with these, she would twice be re-admitted to Friern. She took refuge in day-care institutions and a psychiatric hostel, all the while continuing her therapy, which eventually put her on the road to recovery.This searingly honest, beautifully written memoir is the narrative of the author’s madness years, set inside the wider story of our treatment of psychiatric illness: from the great age of asylums to the current era of community care, ‘Big Pharma’, and quick fixes. It is a meditation on her own experience as well as that of millions of others – both in Europe and in North America – who have suffered, are suffering, and will suffer from mental illness.

    But behind the scenes, Kim was dealing with a tragic secret: her mother, Linda, was suffering from a rare form of dementia that slowly crippled her ability to talk, write and eventually recognize people in her own family.  Where the Light Gets In tells the full story of Linda’s illness—called primary progressive aphasia—from her early-onset diagnosis at the age of 62 through the present day. Kim draws a candid picture of the ways her family reacted for better and worse, and how she, her father and two siblings educated themselves, tried to let go of shame and secrecy, made mistakes, and found unexpected humor and grace in the midst of suffering. Ultimately the bonds of family were strengthened, and Kim learned ways to love and accept the woman her mother became. With a moving foreword by actor and advocate Michael J. Fox, Where the Light Gets In is a heartwarming tribute to the often fragile yet unbreakable relationships we have with our mothers.

    When a small vial arrives in her mailbox from "Lewis Carroll," Ayelet Waldman is at a low point. Her mood storms have become intolerably severe; she has tried nearly every medication possible; her husband and children are suffering with her. So she opens the vial, places two drops on her tongue, and joins the ranks of an underground but increasingly vocal group of scientists and civilians successfully using therapeutic microdoses of LSD. As Waldman charts her experience over the course of a month--bursts of productivity, sleepless nights, a newfound sense of equanimity--she also explores the history and mythology of LSD, the cutting-edge research into the drug, and the byzantine policies that control it. Drawing on her experience as a federal public defender, and as the mother of teenagers, and her research into the therapeutic value of psychedelics, Waldman has produced a book that is eye-opening, often hilarious, and utterly enthralling.

    Born to survivalists in the mountains of Idaho, she prepared for the end of the world by stockpiling home-canned peaches and sleeping with her "head-for-the-hills bag". In the summer she stewed herbs for her mother, a midwife and healer, and in the winter she salvaged in her father's junkyard.Her father forbade hospitals, so Tara never saw a doctor or nurse. Gashes and concussions, even burns from explosions, were all treated at home with herbalism. The family was so isolated from mainstream society that there was no one to ensure the children received an education and no one to intervene when one of Tara's older brothers became violent.Then, lacking any formal education, Tara began to educate herself. She taught herself enough mathematics and grammar to be admitted to Brigham Young University, where she studied history, learning for the first time about important world events like the Holocaust and the civil rights movement. Her quest for knowledge transformed her, taking her over oceans and across continents, to Harvard and to Cambridge. Only then would she wonder if she'd traveled too far, if there was still a way home.Educated is an account of the struggle for self-invention. It is a tale of fierce family loyalty and of the grief that comes with severing the closest of ties. With the acute insight that distinguishes all great writers, Westover has crafted a universal coming-of-age story that gets to the heart of what an education is and what it offers: the perspective to see one's life through new eyes and the will to change it.