It could be an oddball researcher’s genius insight, a catalyzing moment in geopolitical history, a new breakthrough technology, or an unexpected but welcome side effect discovered during clinical trials. Piece together these stories, as Thomas Hager does in this remarkable, century-spanning history, and you can trace the evolution of our culture and the practice of medicine.  ​Beginning with opium, the “joy plant,” which has been used for 10,000 years, Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.

    Seven days. One big secret. The author of The Coincidence of Coconut Cake unfolds a mother-daughter story told by three women whose time to reckon with a life-altering secret is running out.Gina Zoberski wants to make it through one day without her fastidious mother, Lorraine, cataloguing all her faults, and her sullen teenage daughter, May, snubbing her. Too bad there’s no chance of that. Her relentlessly sunny disposition annoys them both, no matter how hard she tries. Instead, Gina finds order and comfort in obsessive list-making and her work at Grilled G’s, the gourmet grilled cheese food truck built by her late husband.But when Lorraine suffers a sudden stroke, Gina stumbles upon a family secret Lorraine's kept hidden for forty years. In the face of her mother’s failing health and her daughter’s rebellion, this optimist might find that piecing together the truth is the push she needs to let go...

    As body armor and advanced trauma care helped save the lives—if not the limbs—of American soldiers fighting in Afghanistan and Iraq, Walter Reed quickly became the world leader in amputee rehabilitation. But no matter the injury, physical therapy began the moment the soldiers emerged from surgery. Days at Walter Reed were intense, chaotic, consuming, and heartbreaking, but they were also filled with camaraderie and humor. Working in a glassed-in fishbowl gymnasium, Levine, her colleagues, and their combat-injured patients were on display at every moment to tour groups, politicians, and celebrities. Some would shudder openly at the sight—but inside the glass and out of earshot, the PTs and the patients cracked jokes, played pranks, and compared stumps. With dazzling storytelling, Run, Don’t Walk introduces a motley array of oddball characters including:  Jim, a retired lieutenant-colonel who stays up late at night baking cake after cake, and the militant dietitian who is always after him; a surgeon who only speaks in farm analogies; a therapy dog gone rogue; —and Levine’s toughest patient, the wild, defiant Cosmo, who comes in with one leg amputated and his other leg shattered. Entertaining, engrossing, and ultimately inspiring, Run, Don’t Walk is a fascinating look into a hidden world.

    People in this middle place have sustained traumatic brain injuries or are the victims of stroke or degenerative diseases, such as Alzheimer’s and Parkinson’s. Many are oblivious to the outside world, and their doctors believe they are incapable of thought. But a sizeable number are experiencing something different: intact minds adrift deep within damaged brains and bodies. Following Owen’s journey of exciting medical discovery, Into the Gray Zone asks some tough and terrifying questions, such as: What is life like for these patients? What can their families and friends do to help them? What are the ethical implications for religious organizations, politicians, the Right to Die movement, and even insurers? And perhaps most intriguing of all: in defining what a life worth living is, are we too concerned with the physical and not giving enough emphasis to the power of thought? What, truly, defines a satisfying life?

    She is assured that 90 percent of Bell’s palsy patients see spontaneous improvement and experience a full recovery. Like Ruhl’s own mother. But Sarah is in the unlucky ten percent. And for a woman, wife, mother, and artist working in theater, the paralysis and the disconnect between the interior and exterior brings significant and specific challenges. So Ruhl begins an intense decade-long search for a cure while simultaneously grappling with the reality of her new face—one that, while recognizably her own—is incapable of accurately communicating feelings or intentions. In a series of piercing, witty, and lucid meditations, Ruhl chronicles her journey as a patient, wife, mother, and artist. She explores the struggle of a body yearning to match its inner landscape, the pain of postpartum depression, the story of a marriage, being a playwright and working mom to three small children, and the desire for a resilient spiritual life in the face of illness. Brimming with insight, humility, and levity, Smile is a triumph by one of America’s leading playwrights. It is an intimate examination of loss and reconciliation, and above all else, the importance of perseverance and hope in the face of adversity.

    . . . I want to have words for what my bones know."By age thirty, Stephanie Foo was successful on paper: She had her dream job as an award-winning radio producer at This American Life and a loving boyfriend. But behind her office door, she was having panic attacks and sobbing at her desk every morning. After years of questioning what was wrong with herself, she was diagnosed with complex PTSD--a condition that occurs when trauma happens continuously, over the course of years.Both of Foo's parents abandoned her when she was a teenager, after years of physical and verbal abuse and neglect. She thought she'd moved on, but her new diagnosis illuminated the way her past continued to threaten her health, relationships, and career. She found limited resources to help her, so Foo set out to heal herself, and to map her experiences onto the scarce literature about C-PTSD.In this deeply personal and thoroughly researched account, Foo interviews scientists and psychologists and tries a variety of innovative therapies. She returns to her hometown of San Jose, California, to investigate the effects of immigrant trauma on the community, and she uncovers family secrets in the country of her birth, Malaysia, to learn how trauma can be inherited through generations. Ultimately, she discovers that you don't move on from trauma--but you can learn to move with it.Powerful, enlightening, and hopeful, What My Bones Know is a brave narrative that reckons with the hold of the past over the present, the mind over the body--and examines one woman's ability to reclaim agency from her trauma.

    There have been exhilarating highs and devastating lows, but his love for the practice of neurosurgery has never wavered. Following the publication of his celebrated New York Times bestseller Do No Harm, Marsh retired from his full-time job in England to work pro bono in Ukraine and Nepal. In Admissions, he describes the difficulties of working in these troubled, impoverished countries and the further insights it has given him into the practice of medicine. Marsh also faces up to the burden of responsibility that can come with trying to reduce human suffering. Unearthing memories of his early days as a medical student and the experiences that shaped him as a young surgeon, he explores the difficulties of a profession that deals in probabilities rather than certainties and where the overwhelming urge to prolong life can come at a tragic cost for patients and those who love them. Reflecting on what forty years of handling the human brain has taught him, Marsh finds a different purpose in life as he approaches the end of his professional career and a fresh understanding of what matters to us all in the end.

    Jacobs undergoes a hilarious, heartfelt quest to understand what constitutes family—where it begins and how far it goes—and attempts to untangle the true meaning of the “Family of Humankind.”A.J. Jacobs has received some strange emails over the years, but this note was perhaps the strangest: “You don’t know me, but I’m your eighth cousin. And we have over 80,000 relatives of yours in our database.” That’s enough family members to fill Madison Square Garden four times over. Who are these people, A.J. wondered, and how do I find them? So began Jacobs’s three-year adventure to help build the biggest family tree in history. Jacobs’s journey would take him to all seven continents. He drank beer with a US president, found himself singing with the Mormon Tabernacle Choir, and unearthed genetic links to Hollywood actresses and real-life scoundrels. After all, we can choose our friends, but not our family. “Whether he’s posing as a celebrity, outsourcing his chores, or adhering strictly to the Bible, we love reading about the wacky lifestyle experiments of author A.J. Jacobs” (Entertainment Weekly). Now Jacobs upends, in ways both meaningful and hilarious, our understanding of genetics and genealogy, tradition and tribalism, identity and connection. It’s All Relative is a fascinating look at the bonds that connect us all.

    He wondered at first if some goo or gunk had worked its way into his right eye. But this was no fleeting annoyance, no fixable inconvenience. Overnight, a rare stroke had cut off blood to one of his optic nerves, rendering him functionally blind in that eye—forever. And he soon learned from doctors that the same disorder could ravage his left eye, too. He could lose his sight altogether. In The Beauty of Dusk, Bruni hauntingly recounts his adjustment to this daunting reality, a medical and spiritual odyssey that involved not only reappraising his own priorities but also reaching out to, and gathering wisdom from, longtime friends and new acquaintances who had navigated their own traumas and afflictions. The result is a poignant, probing, and ultimately uplifting examination of the limits that all of us inevitably encounter, the lenses through which we choose to evaluate them and the tools we have for perseverance. Bruni’s world blurred in one sense, as he experienced his first real inklings that the day isn’t forever and that light inexorably fades, but sharpened in another. Confronting unexpected hardship, he felt more blessed than ever before. There was vision lost. There was also vision found.

    But when his mother insisted she was too poor and not good enough, he broke off the engagement. A heartbroken Marya left Poland for Paris, where she would attend the Sorbonne to study chemistry and physics. Eventually Marie Curie would go on to change the course of science forever and be the first woman to win a Nobel Prize.But what if she had made a different choice?What if she had stayed in Poland, married Kazimierz at the age of twenty-four, and never attended the Sorbonne or discovered radium? What if she had chosen a life of domesticity with a constant hunger for knowledge in Russian Poland where education for women was restricted, instead of studying science in Paris and meeting Pierre Curie?Entwining Marie Curie’s real story with Marya Zorawska’s fictional one, Half Life explores loves lost and destinies unfulfilled—and probes issues of loyalty and identity, gender and class, motherhood and sisterhood, fame and anonymity, scholarship and knowledge. Through parallel contrasting versions of Marya’s life, Jillian Cantor’s unique historical novel asks what would have happened if a great scientific mind was denied opportunity and access to education. It examines how the lives of one remarkable woman and the people she loved – as well as the world at large and course of science and history—might have been irrevocably changed in ways both great and small.

    Their father had gone to sea the previous Friday, the boys told their neighbours, and their mother was visiting her family in Liverpool. Over the next ten days Robert and Nattie spent extravagantly, pawning their parents' valuables to fund trips to the theatre and the seaside. But as the sun beat down on the Coombes house, a strange smell began to emanate from the building. When the police were finally called to investigate, the discovery they made sent the press into a frenzy of horror and alarm, and Robert and Nattie were swept up in a criminal trial that echoed the outrageous plots of the 'penny dreadful' novels that Robert loved to read. In The Wicked Boy, Kate Summerscale has uncovered a fascinating true story of murder and morality - it is not just a meticulous examination of a shocking Victorian case, but also a compelling account of its aftermath, and of man's capacity to overcome the past.

    Forced to remain inside until they'd "proven" themselves sane, all eight emerged with alarming diagnoses and even more troubling stories of their treatment. Rosenhan's study broke open the field of psychiatry, closing down institutions and changing mental health diagnosis forever. But, as Cahalan's new research shows, very little in this saga is exactly as it seems. What really happened behind those closed asylum doors, and what does it mean for our understanding of mental illness today?

    It is a gripping story about the consequences of a trivial robbery gone terribly wrong in a remote village of western Kansas.But what if robbery was not the motive at all, but something more sinister? And why would the Kansas Bureau of Investigation press the Attorney General to launch a ruthless four-year legal battle to prevent fresh details of the State’s most famous crime from being made public, so many years after the case had been solved?Based on stunning new details discovered in the personal journals and archives of former KBI Director Harold Nye—and corroborated by letters written by Richard Hickock, one of the killers on Death Row—“And Every Word Is True” meticulously lays out a vivid and startling new view of the investigation, one that will keep readers on the edge of their seats as they pick up where Capote left off. Even readers new to the story will find themselves drawn into a spellbinding forensic investigation that reads like a thriller, adding new perspectives to the classic tale of an iconic American crime.

    He had gone to medical school in Israel and spent time there as a teenager; now he was going to give something back to the land he loved. But in the wake of a financial crisis at the hospital, Waldman, with considerable regret, left Hadassah in 2014 and returned to the United States. This Narrow Space is his poignant memoir of seven years that were filled with a deep sense of accomplishment but also with frustration when regional politics got in the way of his patients' care, and with tension over the fine line he had to walk when the religious traditions of some of his patients' families made it difficult for him to give those children the care he felt they deserved. Navigating the baffling Israeli bureaucracy, the ever-present threat of full-scale war, and the cultural clashes that sometimes spilled into his clinic, Waldman learned to be content with small victories: a young patient whose disease went into remission, brokenhearted parents whose final hours with their child were made meaningful and comforting.Waldman also struggled with his own questions of identity and belief, and with the intractable conflict between Israelis and Palestinians that had become a fact of his daily life. What he learned about himself, about the complex country that he was now a part of, and about the brave and endearing children he cared for--whether they were from Rehavia, Me'ah She'arim, Ramallah, or Gaza City--will move and challenge readers everywhere.

    After college, armed with a backpack, her personal mission statement, and a wad of traveler’s checks, she took off for Australia to see things and do things and Become Interesting.  But it didn’t turn out the way she pictured it. In a matter of months, her savings shot, she had a choice: get a job or go home. That’s how Kelly met John Tanner, a newly widowed father of two looking for a live-in nanny. They chatted for an hour, discussed timing and pay, and a week later, Kelly moved in. And there, in that house in a suburb north of Sydney, 10,000 miles from the house where she was raised, her mother’s voice was suddenly everywhere, nudging and advising, cautioning and directing, escorting her through a terrain as foreign as any she had ever trekked. Every day she spent with the Tanner kids was a day spent reconsidering her relationship with her mother, turning it over in her hands like a shell, straining to hear whatever messages might be trapped in its spiral.   This is a book about the difference between travel and life experience, stepping out and stepping up, fathers and mothers. But mostly it’s about who you admire and why, and how that changes over time.