The Eighth Edition has been thoroughly revised and updated and is available in both print and e-book formats.Janeway s Immunobiology continues to set the standard for currency and authority with its clear writing style and organization, uniform art program, and scientific accuracy. It presents a consistent point of view throughout that of the host s interaction with an environment containing many species of potentially harmful microorganisms. The full-color art program is conceptually coherent and illustrates the processes and mechanisms underlying the concepts in the text. The 16 chapters in this readable, accessible textbook are organized and presented in such a way as to help deliver a complete one-semester immunology course, beginning with innate immunity, then moving to adaptive immunity, and ending with applied clinical immunology.Discussion questions are provided at the end of Chapters 2 to 16. These questions can be used for review, or as the basis for discussion in class or in informal study groups. Summaries conclude each section and each chapter. As in previous editions, a caduceus icon in the margins indicates topics which are correlated to Case Studies in Immunology, Sixth Edition by Geha and Notarangelo.New in the Eighth EditionInnate immunity has been updated and expanded and is now presented in two separate chapters (Chapters 2 and 3), as well as being further emphasized in the rest of the textbook. Chapter 2 covers antimicrobial peptides and the complement system, and Chapter 3 deals with cellular innate receptors and cell-mediated innate immunity (e.g. TLRs, phagocytosis, NK cells, interferon production, innate-like lymphocytes). The section on complement has been reworked and reconceived explaining the lectin pathway first making it easier to teach by placing it into the context of innate recognition. Evolution is now incorporated throughout the text, helping students see similar strategies used by different organisms. The text and figures of Chapter 7 Signaling Through Immune System Receptors have been revised to present a cohesive synthesis of signaling for immunology, focusing on improved illustration of antigen recognition signaling and lymphocyte activation. Signaling through other receptors is dealt with wherever appropriate throughout the book. Updated chapter on B-cell immune responses (Chapter 10), especially on trafficking of B cells in peripheral lymphoid organs (e.g. lymph nodes) and the locations at which they encounter antigen. Coverage of mucosal immunity (Chapter 12) has been brought up to date, including responses to the commensal microbiota and the role of specialized dendritic cells and the regulatory T cells in maintaining tolerance to food antigens and commensal bacteria. Chapter 13, Failures of Host Defense Mechanisms, has been reorganized and revised to structure an understanding of primary immunodeficiencies in the context of developmental pathways. Chapter 16, Manipulation of the Immune Response, has been heavily revised to include a greater emphasis on clinical issues and a complete update of immunotherapeutics and vaccines. Many new and revised figures illustrate the processes and mechanisms underlying the concepts presented in the text. The icons used have been updated and expanded to incorporate a new emphasis on signaling pathways. New references have been added throughout the text.

    Volume One covers the head, neck, and upper extremities. Volume 2 covers the trunk and lower extremities. Many of the black-and-white illustrations have been converted to color in this edition, and chapter figures include orientational diagrams to give students much needed structural references.

     Four interwoven themes support the major recent developments in the rapidly changing field of biopsychology. Thousands of new references and dozens of new topics have been added to this edition, making Pinel's discussion of and focus on the human element easy and interesting to read. For those interested in physiological and biological psychology.

    In that short time, many doctors decide on the likely diagnosis and best treatment. Often, decisions made this way are correct, but at crucial moments they can also be wrong -- with catastrophic consequences. In this myth-shattering book, Jerome Groopman pinpoints the forces and thought processes behind the decisions doctors make. Groopman explores why doctors err and shows when and how they can -- with our help -- avoid snap judgments, embrace uncertainty, communicate effectively, and deploy other skills that can profoundly impact our health. This book is the first to describe in detail the warning signs of erroneous medical thinking and reveal how new technologies may actually hinder accurate diagnoses. How Doctors Think offers direct, intelligent questions patients can ask their doctors to help them get back on track.Groopman draws on a wealth of research, extensive interviews with some of the country’s best doctors, and his own experiences as a doctor and as a patient. He has learned many of the lessons in this book the hard way, from his own mistakes and from errors his doctors made in treating his own debilitating medical problems.How Doctors Think reveals a profound new view of twenty-first-century medical practice, giving doctors and patients the vital information they need to make better judgments together.

    Encompassing recent advances in molecular pharmacology and brain imaging, Drugs, The Brain and Behavior offers a unique breadth of coverage from historical accounts of drug use, through clinical and preclinical behavioural studies, to the latest research on drug effects in transgenic mouse models.

    The chapters are organized by test type and each chapter begins with a list of the tests covered within the test type, as well as an overview of that category including specimen collection techniques. The tests are presented in a consistent format that includes normal findings, indications, contraindications, potential complications, interfering factors, procedure and patient care, test results and clinical significance, and related tests. This full-color book is easy to use and covers virtually every clinically significant test, including more than 50 new to this edition.

    Now in full color for easier referencing, this New Edition continues the tradition, incorporating a wealth of exciting updates and changes-ensuring you have access to today's authoritative knowledge to best diagnose and treat every pediatric patient you see. Whether you're treating patients in the office or in the hospital, or preparing for the boards, Nelson Textbook of Pediatrics, 18th Edition is your comprehensive guide to providing the best possible care.Get an enhanced focus on general pediatrics with editorial contributions from new editor Dr. Bonita F. Stanton.Treat your inpatient and ambulatory patients more effectively with the absolute latest on new topics such as quality improvement and patient care safety . school violence and bullying . preventive measures . vitamin deficiencies . adolescent rape . effect of war on children . and more.Improve your therapeutic skills with the newest knowledge on the principles of antibiotic therapy . antiviral therapy . antiparasitic therapy . antimycobacterial therapy . and others.Understand the principles of therapy and which drugs and dosages to prescribe for every disease.Locate key content more easily and identify clinical conditions quicker thanks to a new full-color design and full-color photographs.Get an enhanced focus on general pediatrics with editorial contributions from new editor Dr. Bonita F. Stanton.Treat your inpatient and ambulatory patients more effectively with the absolute latest on new topics such as quality improvement and patient care safety *school violence and bullying * preventive measures * vitamin deficiencies * adolescent rape * effect of war on children * and more.Improve your therapeutic skills with the newest knowledge on the principles of antibiotic therapy * antiviral therapy * antiparasitic therapy * antimycobacterial therapy * and others.Understand the principles of therapy and which drugs and dosages to prescribe for every disease.Locate key content more easily and identify clinical conditions quicker thanks to a new full-color design and full-color photographs.

    Molecular Cell Biology stands out from its peers in this course in that it provides a clear introduction to the techniques and experiments of scientists past and present, not just an "encyclopedia" of information.  This experimental emphasis, together with a solid pedagogical framework in the chapters, provides the clearest, most cutting-edge text available.

    Gravetter, and co-author Lori-Ann B. Forzano have written a text for research methods that helps you see how interesting and exciting experimental and non-experimental research can be. Inviting and conversational, RESEARCH METHODS FOR THE BEHAVIORAL SCIENCES, Third Edition, leads you through the research process from start to finish. The text opens with tips and strategies for generating research ideas, moves to selecting measures and participants, and then offers an examination of research strategy and design. This step-by-step approach emphasizes the decisions researchers must make at each stage of the process. The authors avoid a "cookbook" approach to the facts by linking terminology with applied concepts; their "lecture in a book" style emphasizes discussion and explanation of topics. Each chapter ends with a set of exercises and activities.

    It could be an oddball researcher’s genius insight, a catalyzing moment in geopolitical history, a new breakthrough technology, or an unexpected but welcome side effect discovered during clinical trials. Piece together these stories, as Thomas Hager does in this remarkable, century-spanning history, and you can trace the evolution of our culture and the practice of medicine.  ​Beginning with opium, the “joy plant,” which has been used for 10,000 years, Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.

    Terminology and complex medical processes are described in an easy-to-understand manner that is readily accessible to learners of all levels. The Language of Medicine brings medical terms to life with a text/workbook format organized by body systems, offering additional chapters on specific key areas of health care, such as cancer and psychiatry. Anatomy and physiology sections are generously illustrated in full color and reinforced with exercises on combining forms and word parts.

    This work offers accesible coverage of the fundamentals of electrodynamics, enhanced with with discussion points, examples and exercises.

    At the time, Watson was only 24, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science's greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions & bitter rivalries. With humility unspoiled by false modesty, Watson relates his & Crick's desperate efforts to beat Linus Pauling to the Holy Grail of life sciences, the identification of the basic building block of life. Never has a scientist been so truthful in capturing in words the flavor of his work.

    Part One presents the general principles of pathophysiology and discusses the influence of the environment and the role of genetics in the development of disease. Part Two, organized by body system, examines normal anatomy and physiology, alterations of function in adults, and alterations of function in children.

    The physical examination unit is organized by body system, pedagogically and clinically the most logical and efficient way to learn and perform health assessment. Each chapter has five major sections: (1) Structure and Function (A&P); (2) Subjective Data (history); (3) Objective Data (skills, expected findings, and common variations for healthy people and selected abnormal findings); (4) Abnormal Findings (illustrations of related disorders and conditions in atlas format); and (5) Application and Documentation (sample charting, clinical case studies, nursing diagnoses, and critical thinking questions tied to the Saunders video series).