Just a half century ago, this idea was revolutionary. In April 1953, James Watson and Francis Crick published in Nature their groundbreaking work revealing the double helix structure of DNA. While this discovery received wide attention from both mainstream media and the academic community, it was just one part of the bigger story in this history of molecular biology. By the mid-1950s, the scientific community confirmed that genes were indeed comprised of DNA; they just needed to crack the genetic code—and the race was on. Life’s Greatest Secret is the full and rich history of this challenge and the characters—many of whom were not biologists—whose work contributed to this grand scientific endeavor: mathematician and father of cybernetics Norbert Wiener, physicist Erwin Schrödinger, information theorist Claude Shannon, and biologists Jacques Monod and Marshall Nirenberg.In Life’s Greatest Secret, science historian and zoologist Matthew Cobb shows that the race to crack the genetic code was mostly a matter of craft—individuals or small groups struggling with ideas and concepts as much as they were with facts, trying to find the right experiment to answer the right questions, even if they didn’t know what the questions were, and finding that, even when the most definitive answer served mostly to reveal more ignorance, whether in 1953, with Watson and Crick, or in 1961, when Nirenberg and Matthaei showed how DNA codes for specific amino acids, and again and again thereafter, or in 2000, with the first publication of a human genome. Each discovery was a leap forward in our understanding of the natural world and our place within in, akin to the discoveries of Galileo and Einstein in the realm of physics, or the publication of Darwin’s On the Origin of Species. And each served to show how much bigger the problem was that anyone had previously imagined, a trend that continues, as Cobb shows, even today, whether we are discussing gene regulation, epigenetics, or GMOs.Life’s Greatest Secret is a story of ideas and of experimentation, of ingenuity, insight, and dead-ends, in the hunt to make the greatest discovery of twentieth century biology. Ultimately, though, this is a story of humans exploring what it is that makes us human.

    Evo Devo Evolutionary Developmental Biology is the new science that has finally cracked open the box. Within the pages of his rich and riveting book, Sean B. Carroll explains how we are discovering that complex life is ironically much simpler than anyone ever expected.

    Life remains the only way to make life. Are we still missing a vital ingredient in its creation?      Like Richard Dawkins' The Selfish Gene, which provided a new perspective on how evolution works, Life on the Edge alters our understanding of our world's fundamental dynamics. Bringing together first-hand experience at the cutting edge of science with unparalleled gifts of explanation, Jim Al-Khalili and Johnjoe Macfadden reveal that missing ingredient to be quantum mechanics; the phenomena that lie at the heart of this most mysterious of sciences. Drawing on recent ground-breaking experiments around the world, each chapter in Life on the Edge engages by illustrating one of life's puzzles: How do migrating birds know where to go? How do we really smell the scent of a rose? How do our genes copy themselves with such precision? Life on the Edge accessibly reveals how quantum mechanics can answer these probing questions of the universe. Guiding the reader through the rapidly unfolding discoveries of the last few years, Al-Khalili and McFadden communicate the excitement of the explosive new field of quantum biology and its potentially revolutionary applications, while offering insights into the biggest puzzle of all: what is life? As they brilliantly demonstrate in these groundbreaking pages, life exists on the quantum edge.

    Each clique of scientists has a part of the story correct, but new evidence shows they are all fundamentally wrong.On the one side, we have academics highlighting the astonishing fossil record of China with multiple sites now producing modern human fossils aged between 80 - 120 thousand years, or older. Several extremely ancient fossil finds in China, including Dali, Maba and Jinniushan, place archaic Homo sapiens in this region up to 260,000 years ago.On the other side, we have scientists pointing to Africa's impressive fossil record with its evidence of potential ancestors going back around 6 million years. The evidence of extreme genetic diversity among Africans and the discovery of 300,000-year-old archaic Homo sapiens fossils in Morocco tends to further support the idea that humans came out from Africa. We can understand why both sides are so sure of their positions, and why the debate continues. While leading academics focussed on their own agendas, they overlooked significant evidence. Between the two poles of Out of Africa and Out of Asia Theory, exists a 'Middle Way'. The Forgotten Exodus: The Into Africa Theory of Human Evolution, reveals that within the known fossil record, the current genetic studies and recent paleoclimate models there is compelling evidence for a superior theory of human origins, representing a paradigm displacement.The Into Africa Theory does not dispute the evidence placing the earliest hominins in Africa.However, it does not agree with the consensus view that Homo sapiens emerged there first and later migrated to Eurasia.The Into Africa Theory recognises the extraordinary evidence for critical stages in our development occurring in East and Southeast Asia. It is abundantly clear that as a new concerted effort to gather and evaluate fossil evidence begins in earnest we see astonishing new discoveries. The Into Africa Theorydisputes the claims of Out of Africa and Out of Asia(or Europe) adherents over the starting point for the migration which populated Eurasia approximately 60,000 years ago and identifies the actual location.Amazing facts that you will encounter:-Homo heidelbergensis was not ancestral to modern humans -Denisovan fossils in Siberia carried DNAfrom Australian Aboriginals-An Indonesian supervolcano brought about the end for multiple hominin species-Climate catastrophe locked humans in Africa from 73,000 to 59,000 years ago-There is no African fossil DNA over 10,000 years in age-While supposedly isolated, Aboriginal Australians interbred with Denisovans 44,000 years agoYou will gain access to a long-forgotten conversation involving the famous evolutionary scientists Allan Wilson and Rebecca Cann, in which they admitted that their data suggested Aboriginal Australians were ancestral to all modern humans.Learn why the appearance of the haplogroups foundational to Eurasians, L3 and CT, had to come from a population incursion rather than an in-situ mutation.Explore the cutting-edge scientific findings of 2016 and 2017 alongside a broad range of anomalies long suppressed or ignored in academic circles.The Forgotten Exodus' author Bruce R. Fenton began his journey towards a new understanding of human origins after an expedition to a mysterious megalithic complex in the Ecuadorian Amazon. The Information Systems professional and lifelong scholar of ancient cultures, found himself tracing the threads of the human story across six continents and through 6,000,000 years of history. You will come away with a unique view of humanity and a sense of excitement for revelations still set to arrive. This book reminds all of us that we have a collective ability to overcome enormous obstacles.

    Tedford have spent the past 20 years studying the evolutionary history of the family Canidae. Both are well known for having established the modern framework for the evolutionary relationship of canids. Combining their research with Mauricio Ant�n's impeccable reconstructions of both extinct and extant species, Wang and Tedford present a remarkably detailed and nuanced portrait of the origin and evolution of canids over the past 40 million years.The authors cull their history from the most recent scientific research conducted on the vast collections of the American Museum of Natural History and other leading institutions. The fossil record of the Canidae, particularly those from their birth place in North America, are the strongest of their kind among known groups of carnivorans. Such a wonderfully detailed evolutionary history provides access to a natural history that is not possible with many other groups of carnivorans.With their rich fossil record, diverse adaptations to various environments, and different predatory specializations, canids are an ideal model organism for the mapping of predator behavior and morphological specializations. They also offer an excellent contrast to felids, which remain entrenched in extreme predatory specializations. The innovative illustrated approach in this book is the perfect accompaniment to an extremely important branch of animal and fossil study. It transforms the science of paleontology into a thrilling visual experience and provides an unprecedented reference for anyone fascinated by dogs.

    Many new or revised figures and photographs, study questions and a glossary of key terms have been added.

    The first volume in this annual series of the best writing by Americans, meticulously selected by bestselling author James Gleick, one of the foremost chronicles of scientific social history, debuts with a stellar collection of writers and thinkers.  Many of these cutting-edge essays offer glimpses of new realms of discovery and thought, exploring territory that is unfamiliar to most of us, or finding the unexpected in the midst of the familiar.  Nobel Laureate physicist Steven Weinberg challenges the idea of whether the universe has a designer; Pulitzer Prize winner Natalie Angier reassesses caveman (and-woman) couture; bestselling author and Darwinian theorist Stephen Jay Gould makes a claim for the man whose ideas Darwin discredited; Timothy Ferris proposes a realistic alternative to wrap-speed interseller travel; neurologist and bestselling author Oliver Sacks reminisces about his first loves-chemistry and math.  This diverse, stimulating and accessible collection is required reading for anyone who wants to travel to the frontier of knowledge.

    It says what most scientists and politicians are afraid to say about what research can and, perhaps more importantly, cannot deliver on topics ranging from sexuality, race and genetic modification to stem cells, cloning, modern medicine, fertility treatment, creationism and bioterrorism.Having worked at the heart of government science, at the most prestigious science publishing company in the world, and in one of the world's leading biology institutions the author has a unique view of the politics, culture and reach of science. He illustrates how we are facing dangerous times where political agendas and public misunderstanding are hobbling truly novel work and hence calls for wide reaching changes in science education, funding, publishing and promulgation.

    He spent two years gathering information that demonstrates this and along the way interviewed more than a hundred experts in a number of different fields. Among them were parapsychologists, medical doctors, psychologists, psychiatrists, quantum physicists, and researchers into the true nature of reality. Specific examples are presented that indicate what happens when we die, for example that memories can be formed and retained despite a subject’s brain having been shutdown and the blood drained from it. Questions such as whether or not you will be able to communicate with living loved ones after death are addressed, if it is possible to be reborn, and what might be missing from reproductive theory to explain the various phenomena indicated in the many case histories and scientific investigations presented. All of us will someday cross the border to what Shakespeare called "The undiscovered country." As long as we must make that trip, wouldn’t it be smart to find out where we are going and what to expect when we get there?

    It includes extensive material on molecular biology, and presents biochemistry from a chemist's perspective.

    They force us to confront a fundamental biological problem: how can something as large and complex as a human body organize itself from the simplicity of a fertilized egg? A convergence of ideas from embryology, genetics, physics, networks, and control theory has begun to provide real answers. Based on the central principle of 'adaptive self-organization, ' it explains how the interactions of many cells, and of the tiny molecular machines that run them, can organize tissue structures vastly larger than themselves, correcting errors as they go along and creating new layers of complexity where there were none before.Life Unfolding tells the story of human development from egg to adult, from this perspective, showing how our whole understanding of how we come to be has been transformed in recent years. Highlighting how embryological knowledge is being used to understand why bodies age and fail, Jamie A. Daviesexplores the profound and fascinating impacts of our newfound knowledge.

    Although molecular topics are presented first, instructors can assign the chapters in any sequence. Pedagogical features such as chapter-opening “Key Questions” and strategically placed “Keynotes” help readers to efficiently master genetic concepts. The Genetics Place Companion Website contains interactive iActivities and narrated animations that help readers visualize and understand processes and concepts that are illustrated in the book. Genetics: An Introduction, DNA: The Genetic Material, DNA Replication, Gene Control of Proteins, Gene Expression: Transcription,Gene Expression: Translation, DNA Mutation, DNA Repair, and Transposable Elements, Structural Genomics, Functional and Comparative Genomics, Recombinant DNA Technology, Mendelian Genetics, Chromosomal Basis of Inheritance, Extensions of and Deviations from Mendelian Genetic Principles, Genetic Mapping in Eukaryotes, Genetics of Bacteria and Bacteriophages, Variations in Chromosome Structure and Number, Regulation of Gene Expression in Bacteria and Bacteriophages, Regulation of Gene Expression in Eukaryotes, Genetic Analysis of Development, Genetics of Cancer, Quantitative Genetics, Population Genetics, Molecular Evolution Intended for those interested in learning the basics of genetics

    Pulitzer Prize–winning author Siddhartha Mukherjee, a leading cancer physician and researcher, selects the year’s top science and nature writing from journalists who dive into their fields with curiosity and passion, delivering must-read articles from a wide array of fields.

    Evolutionists have never been able to completely explain why birdsong is so inventive and why many species devote so many hours to singing. The standard explanations of defending territories and attracting mates don't begin to account for the variety and energy that the commonest birds exhibit. Is it possible that birds sing because they like to? This seemingly naive explanation is starting to look more and more like the truth. Why Birds Sing is a lyric exploration of birdsong that blends the latest scientific research with a deep understanding of musical beauty and form. Drawing on conversations with neuroscientists, ecologists, and composers, it is the first book to investigate the elusive question of why birds sing and what their song means to both avian and human ears. Whether playing his clarinet with the whitecrested laughing thrush in Pittsburgh, or jamming in the Australian winter breeding grounds of the Albert's lyrebird, Rothenberg immerses himself in the heart and soul of birdsong. He approaches the subject as a naturalist, philosopher, musician, and investigator. An intimate look at the mostlovely of natural phenomena, Why Birds Sing is a beautifully written exploration of a phenomenon that's at once familiar and profoundly alien.