Life's Greatest Secret: The Race to Crack the Genetic Code


Matthew Cobb - 2015
    Just a half century ago, this idea was revolutionary. In April 1953, James Watson and Francis Crick published in Nature their groundbreaking work revealing the double helix structure of DNA. While this discovery received wide attention from both mainstream media and the academic community, it was just one part of the bigger story in this history of molecular biology. By the mid-1950s, the scientific community confirmed that genes were indeed comprised of DNA; they just needed to crack the genetic code—and the race was on. Life’s Greatest Secret is the full and rich history of this challenge and the characters—many of whom were not biologists—whose work contributed to this grand scientific endeavor: mathematician and father of cybernetics Norbert Wiener, physicist Erwin Schrödinger, information theorist Claude Shannon, and biologists Jacques Monod and Marshall Nirenberg.In Life’s Greatest Secret, science historian and zoologist Matthew Cobb shows that the race to crack the genetic code was mostly a matter of craft—individuals or small groups struggling with ideas and concepts as much as they were with facts, trying to find the right experiment to answer the right questions, even if they didn’t know what the questions were, and finding that, even when the most definitive answer served mostly to reveal more ignorance, whether in 1953, with Watson and Crick, or in 1961, when Nirenberg and Matthaei showed how DNA codes for specific amino acids, and again and again thereafter, or in 2000, with the first publication of a human genome. Each discovery was a leap forward in our understanding of the natural world and our place within in, akin to the discoveries of Galileo and Einstein in the realm of physics, or the publication of Darwin’s On the Origin of Species. And each served to show how much bigger the problem was that anyone had previously imagined, a trend that continues, as Cobb shows, even today, whether we are discussing gene regulation, epigenetics, or GMOs.Life’s Greatest Secret is a story of ideas and of experimentation, of ingenuity, insight, and dead-ends, in the hunt to make the greatest discovery of twentieth century biology. Ultimately, though, this is a story of humans exploring what it is that makes us human.

Nonsense on Stilts: How to Tell Science from Bunk


Massimo Pigliucci - 2008
    More and more parents are refusing to vaccinate their children for fear it causes autism, though this link can been consistently disproved. And about 40 percent of Americans believe that the threat of global warming is exaggerated, despite near consensus in the scientific community that manmade climate change is real.Why do people believe bunk? And what causes them to embrace such pseudoscientific beliefs and practices? Noted skeptic Massimo Pigliucci sets out to separate the fact from the fantasy in this entertaining exploration of the nature of science, the borderlands of fringe science, and—borrowing a famous phrase from philosopher Jeremy Bentham—the nonsense on stilts. Presenting case studies on a number of controversial topics, Pigliucci cuts through the ambiguity surrounding science to look more closely at how science is conducted, how it is disseminated, how it is interpreted, and what it means to our society. The result is in many ways a “taxonomy of bunk” that explores the intersection of science and culture at large.No one—not the public intellectuals in the culture wars between defenders and detractors of science nor the believers of pseudoscience themselves—is spared Pigliucci’s incisive analysis. In the end, Nonsense on Stilts is a timely reminder of the need to maintain a line between expertise and assumption. Broad in scope and implication, it is also ultimately a captivating guide for the intelligent citizen who wishes to make up her own mind while navigating the perilous debates that will affect the future of our planet.

Cro-Magnon: How the Ice Age Gave Birth to the First Modern Humans


Brian M. Fagan - 2010
    The prolonged encounter between the Cro-Magnons and the archaic Neanderthals and between 45,000 and 30,000 years ago was one of the defining moments of history. The Neanderthals survived for some 15,000 years in the face of the newcomers, but were finally pushed aside by the Cro-Magnons' vastly superior intellectual abilities and cutting-edge technologies, which allowed them to thrive in the intensely challenging climate of the Ice Age.What do we know about this remarkable takeover? Who were the first modern Europeans and what were they like? How did they manage to thrive in such an extreme environment? And what legacy did they leave behind them after the cold millennia? The age of the Cro-Magnons lasted some 30,000 years?longer than all of recorded history. Cro-Magnon is the story of a little known, yet seminal, chapter of human experience.

Life After Death, Powerful Evidence You Will Never Die


Stephen Hawley Martin - 2015
    He spent two years gathering information that demonstrates this and along the way interviewed more than a hundred experts in a number of different fields. Among them were parapsychologists, medical doctors, psychologists, psychiatrists, quantum physicists, and researchers into the true nature of reality. Specific examples are presented that indicate what happens when we die, for example that memories can be formed and retained despite a subject’s brain having been shutdown and the blood drained from it. Questions such as whether or not you will be able to communicate with living loved ones after death are addressed, if it is possible to be reborn, and what might be missing from reproductive theory to explain the various phenomena indicated in the many case histories and scientific investigations presented. All of us will someday cross the border to what Shakespeare called "The undiscovered country." As long as we must make that trip, wouldn’t it be smart to find out where we are going and what to expect when we get there?

A Short History of Humanity: A New History of Old Europe


Johannes Krause - 2019
    Krause is a pioneer in the revolutionary new science of archaeogenetics, archaeology augmented by revolutionary DNA sequencing technology, which has allowed scientists to uncover a new version of human history reaching back more than 100,000 years. Using this technology to re-examine human bones from the distant past, Krause has been able to map not only the genetic profiles of the dead, but also their ancient journeys.In this concise narrative he tells us their long-forgotten stories of migration and intersection. It's well known that many human populations carry genetic material from Neanderthals; but, as Krause and his colleagues discovered, we also share DNA with a newly uncovered human form, the Denisovans. We know now that a wave of farmers from Anatolia migrated into Europe 8,000 years ago, essentially displacing the dark-skinned, blue-eyed hunter-gatherers who preceded them. The farmer DNA is one of the core genetic components of contemporary Europeans and European Americans. Though the first people to cross into North and South America have long been assumed to be primarily of East Asian descent, we now know that they also share DNA with contemporary Europeans and European Americans. Genetics has an unfortunate history of smuggling in racist ideologies, but our most cutting-edge science tells us that genetic categories in no way reflect national borders.Krause vividly introduces us to prehistoric cultures such as the Aurignacians, innovative artisans who carved animals, people, and even flutes from bird bones more than 40,000 years ago; the Varna, who buried their loved ones with gold long before the Pharaohs of Egypt; and the Gravettians, big-game hunters who were Europe's most successful early settlers until they perished in the ice age. This informed retelling of the human epic confirms that immigration and genetic mingling have always defined our species and that who we are is a question of culture not genetics.

Sex at Dawn: The Prehistoric Origins of Modern Sexuality


Christopher Ryan - 2010
    Mainstream science--as well as religious and cultural institutions--has maintained that men and women evolved in families in which a man's possessions and protection were exchanged for a woman's fertility and fidelity. But this narrative is collapsing. Fewer and fewer couples are getting married, and divorce rates keep climbing as adultery and flagging libido drag down even seemingly solid marriages.How can reality be reconciled with the accepted narrative? It can't be, according to renegade thinkers Christopher Ryan and Cacilda Jethá. While debunking almost everything we "know" about sex, they offer a bold alternative explanation in this provocative and brilliant book.Ryan and Jethá's central contention is that human beings evolved in egalitarian groups that shared food, child care, and, often, sexual partners. Weaving together convergent, frequently overlooked evidence from anthropology, archaeology, primatology, anatomy, and psychosexuality, the authors show how far from human nature monogamy really is. Human beings everywhere and in every era have confronted the same familiar, intimate situations in surprisingly different ways. The authors expose the ancient roots of human sexuality while pointing toward a more optimistic future illuminated by our innate capacities for love, cooperation, and generosity.With intelligence, humor, and wonder, Ryan and Jethá show how our promiscuous past haunts our struggles over monogamy, sexual orientation, and family dynamics. They explore why long-term fidelity can be so difficult for so many; why sexual passion tends to fade even as love deepens; why many middle-aged men risk everything for transient affairs with younger women; why homosexuality persists in the face of standard evolutionary logic; and what the human body reveals about the prehistoric origins of modern sexuality.In the tradition of the best historical and scientific writing, Sex at Dawn unapologetically upends unwarranted assumptions and unfounded conclusions while offering a revolutionary understanding of why we live and love as we do.

How Nature Works: The Science of Self-Organized Criticality


Per Bak - 1996
    This theory describes how many seemingly desperate aspects of the world, from stock market crashes to mass extinctions, avalanches to solar flares, all share a set of simple, easily described properties."...a'must read'...Bak writes with such ease and lucidity, and his ideas are so intriguing...essential reading for those interested in complex systems...it will reward a sufficiently skeptical reader." -NATURE"...presents the theory (self-organized criticality) in a form easily absorbed by the non-mathematically inclined reader." -BOSTON BOOK REVIEW"I picture Bak as a kind of scientific musketeer; flamboyant, touchy, full of swagger and ready to join every fray... His book is written with panache. The style is brisk, the content stimulating. I recommend it as a bracing experience." -NEW SCIENTIST

Creation or Evolution: Do We Have to Choose?


Denis Alexander - 2008
    What do we mean by creation and evolution? What are the common scientific objections to evolution? Is evolution atheistic? Who were Adam and Eve? Can the concept of the fall be reconciled with evolutionary theory? How could a God of love create a world where animals kill each other? What about intelligent design? Denis Alexander, director of the Faraday Institute for Science and Religion, helps readers sort out the answers to these tricky questions.

Explaining Humans: What Science Can Teach Us about Life, Love and Relationships


Camilla Pang - 2020
    Desperate for a solution, Camilla asked her mother if there was an instruction manual for humans that she could consult. But, without the blueprint to life, she was hoping for, Camilla began to create her own. Now armed with a PhD in biochemistry, Camilla dismantles our obscure social customs and identifies what it really means to be human using her unique expertise and a language she knows best: science.Through a set of scientific principles, this book examines life's everyday interactions including:- Decisions and the route we take to make them;- Conflict and how we can avoid it;- Relationships and how we establish them;- Etiquette and how we conform to it.Explaining Humans is an original and incisive exploration of human nature and the strangeness of social norms, written from the outside looking in. Camilla's unique perspective of the world, in turn, tells us so much about ourselves - about who we are and why we do it - and is a fascinating guide on how to lead a more connected, happier life.

Darwin for Beginners


Jonathan Miller - 1982
    Along the way we meet a fascinating cast of characters: Darwin's scientific predecessors, his contemporaries (including Alfred Russell Wallace, whose anticipation of natural selection forced Darwin to publish), his opponents, and his successors whose work in modern genetics provided necessary modifications to Darwin's own work.Splendidly illustrated, this clever, witty, highly informative book is the perfect introduction to Darwin's life and thought.

Evolution: The First Four Billion Years


Michael RuseBrian Goodwin - 2009
    Spanning evolutionary science from its inception to its latest findings, from discoveries and data to philosophy and history, this book is an authoritative introduction to evolutionary biology.

The Righteous Mind: Why Good People Are Divided by Politics and Religion


Jonathan Haidt - 2012
     His starting point is moral intuition—the nearly instantaneous perceptions we all have about other people and the things they do. These intuitions feel like self-evident truths, making us righteously certain that those who see things differently are wrong. Haidt shows us how these intuitions differ across cultures, including the cultures of the political left and right. He blends his own research findings with those of anthropologists, historians, and other psychologists to draw a map of the moral domain. He then examines the origins of morality, overturning the view that evolution made us fundamentally selfish creatures. But rather than arguing that we are innately altruistic, he makes a more subtle claim—that we are fundamentally groupish. It is our groupishness, he explains, that leads to our greatest joys, our religious divisions, and our political affiliations. In a stunning final chapter on ideology and civility, Haidt shows what each side is right about, and why we need the insights of liberals, conservatives, and libertarians to flourish as a nation.

iGenetics: A Molecular Approach


Peter J. Russell - 2001
    Although molecular topics are presented first, instructors can assign the chapters in any sequence. Pedagogical features such as chapter-opening “Key Questions” and strategically placed “Keynotes” help readers to efficiently master genetic concepts. The Genetics Place Companion Website contains interactive iActivities and narrated animations that help readers visualize and understand processes and concepts that are illustrated in the book. Genetics: An Introduction, DNA: The Genetic Material, DNA Replication, Gene Control of Proteins, Gene Expression: Transcription,Gene Expression: Translation, DNA Mutation, DNA Repair, and Transposable Elements, Structural Genomics, Functional and Comparative Genomics, Recombinant DNA Technology, Mendelian Genetics, Chromosomal Basis of Inheritance, Extensions of and Deviations from Mendelian Genetic Principles, Genetic Mapping in Eukaryotes, Genetics of Bacteria and Bacteriophages, Variations in Chromosome Structure and Number, Regulation of Gene Expression in Bacteria and Bacteriophages, Regulation of Gene Expression in Eukaryotes, Genetic Analysis of Development, Genetics of Cancer, Quantitative Genetics, Population Genetics, Molecular Evolution Intended for those interested in learning the basics of genetics

Natural Selections: Selfish Altruists, Honest Liars, and Other Realities of Evolution


David Philip Barash - 2007
    . . brilliantly integrat[es] science, literature, and pop culture into elegant and insightful commentaries on the most interesting and important questions of our time. A delightful read.”—Michael Shermer, author of The Science of Good and Evil“Entertaining and thought-provoking.”—Steven Pinker, author of The Blank SlateIf we are, in part, a product of our genes, can free will exist? Incisive and engaging, this indispensable tour of evolutionary biology runs the gamut of contemporary debates, from science and religion to our place in the universe.David Barash is the author of The Myth of Monogamy and Madame Bovary’s Ovaries. He lives in Redmond, Washington.

The Complete Book Of Dinosaurs


Dougal Dixon - 2006
    The ultimate reference to 355 dinosaurs from the Triassic, Jurassic and Cretaceous periods, including more than 900 watercolors, maps, timelines and photographs.Includes the best-known non-dinosaurs such as sea-living placodonts, nothosaurs, plesiosaurs, mosasaurs and ichthyosaurs, as well as the airborne pterosaurs.With informative descriptions, technically accurate profiles, anatomical illustrations, depictions of dinosaur habitats, and maps of fossil sites.