But what if the person receiving the diagnosis--young, physically fit, poised for a bright future--is himself a doctor?At thirty-one David biro has just completed his residency and joined his father's successful dermatology practice. Struck with a rare blood disease that eventually necessitates a bone marrow transplant, Biro relates with honesty and courage the story of his most transforming journey. He is forthright about the advantages that his status as a physician may have afforded him; and yet no such advantage can protect him from the anxiety and doubt brought on by his debilitating therapies. The pressures that Biro's wild "one hundred days" brings to bear on his heretofore well-established identity as a caregiver are enormous--as is the power of this riveting story of survival.

    It infected nearly one-third of the world’s population and killed ten percent of those it struck. In its wake, schools and businesses closed, hospitals became overwhelmed, and the sick spilled out into makeshift care centers in public spaces. Policemen, public transportation workers, and everyday citizens in face masks were a common—and eerie—sight. Yet, discussion of this global pandemic often takes a backseat to World War I and other contemporary events.

    On the eve of this centenary, journalist Johann Hari set off on an epic three-year, thirty-thousand-mile journey into the war on drugs. What he found is that more and more people all over the world have begun to recognize three startling truths: Drugs are not what we think they are. Addiction is not what we think it is. And the drug war has very different motives to the ones we have seen on our TV screens for so long.In Chasing the Scream, Hari reveals his discoveries entirely through the stories of people across the world whose lives have been transformed by this war. They range from a transsexual crack dealer in Brooklyn searching for her mother, to a teenage hit-man in Mexico searching for a way out. It begins with Hari's discovery that at the birth of the drug war, Billie Holiday was stalked and killed by the man who launched this crusade--and it ends with the story of a brave doctor who has led his country to decriminalize every drug, from cannabis to crack, with remarkable results.Chasing the Scream lays bare what we really have been chasing in our century of drug war--in our hunger for drugs, and in our attempt to destroy them. This book will challenge and change how you think about one of the most controversial--and consequential--questions of our time.

    Jails in New York, Los Angeles, and Chicago each house more people with mental illnesses than any hospital. As many as half of all people in America's jails and prisons have a psychiatric disorder. One in four fatal police shootings involves a person with such disorders.In this revelatory book, journalist Alisa Roth goes deep inside the criminal justice system to show how and why it has become a warehouse where inmates are denied proper treatment, abused, and punished in ways that make them sicker.Through intimate stories of people in the system and those trying to fix it, Roth reveals the hidden forces behind this crisis and suggests how a fairer and more humane approach might look. Insane is a galvanizing wake-up call for criminal justice reformers and anyone concerned about the plight of our most vulnerable.

    Today, mental disturbance is most commonly viewed through a medical lens, but societies have also sought to make sense of it through religion or the supernatural, or by constructing psychological or social explanations in an effort to tame the demons of unreason. Madness in Civilization traces the long and complex history of this affliction and our attempts to treat it.Beautifully illustrated throughout, Madness in Civilization takes readers from antiquity to today, painting a vivid and often harrowing portrait of the different ways that cultures around the world have interpreted and responded to the seemingly irrational, psychotic, and insane. From the Bible to Sigmund Freud, from exorcism to mesmerism, from Bedlam to Victorian asylums, from the theory of humors to modern pharmacology, the book explores the manifestations and meanings of madness, its challenges and consequences, and our varied responses to it. It also looks at how insanity has haunted the imaginations of artists and writers and describes the profound influence it has had on the arts, from drama, opera, and the novel to drawing, painting, and sculpture.Written by one of the world’s preeminent historians of psychiatry, Madness in Civilization is a panoramic history of the human encounter with unreason.

    

    His mother’s cooking. His father’s awkward sense of humor. He remembers air conditioning and warm beds and graduation. But all of that was before the end of the world. Now he is a survivor, one of them – part of a roving clan of killers that combs through the ruined neighborhoods and towns, looking for things to steal, men to butcher, women to enslave and abuse. Then he meets a woman who could kill him without blinking, and together they escape the world that was...

    Enduring half a dozen surgeries, the drugs he received were both miraculous and essential to his recovery. But his most profound suffering came several months later when he went into acute opioid withdrawal while following his physician’s orders. Over the course of four excruciating weeks, Rieder learned what it means to be “dope sick”—the physical and mental agony caused by opioid dependence. Clueless how to manage his opioid taper, Travis’s doctors suggested he go back on the drugs and try again later. Yet returning to pills out of fear of withdrawal is one route to full-blown addiction. Instead, Rieder continued the painful process of weaning himself.Rieder’s experience exposes a dark secret of American pain management: a healthcare system so conflicted about opioids, and so inept at managing them, that the crisis currently facing us is both unsurprising and inevitable. As he recounts his story, Rieder provides a fascinating look at the history of these drugs first invented in the 1800s, changing attitudes about pain management over the following decades, and the implementation of the pain scale at the beginning of the twenty-first century. He explores both the science of addiction and the systemic and cultural barriers we must overcome if we are to address the problem effectively in the contemporary American healthcare system.In Pain in America is not only a gripping personal account of dependence, but a groundbreaking exploration of the intractable causes of America’s opioid problem and their implications for resolving the crisis. Rieder makes clear that the opioid crisis exists against a backdrop of real, debilitating pain—and that anyone can fall victim to this epidemic.

    But American Overdose exposes the powerful forces they were up against, including the pharmaceutical industry's coopting of the Food and Drug Administration and Congress in the drive to push painkillers--resulting in the resurgence of heroin cartels in the American heartland. McGreal tells the story, in terms both broad and intimate, of people hit by a catastrophe they never saw coming. Years in the making, its ruinous consequences will stretch years into the future.

    It was once minimized and misunderstood as forgetfulness in the elderly, but Alzheimer’s is now at the forefront of many medical and scientific agendas, for as the world’s population ages, the disease will kill millions more and touch the lives of virtually everyone. The Forgetting is a scrupulously researched, multilayered analysis of Alzheimer’s and its social, medical, and spiritual implications. David Shenk presents us with much more than a detailed explanation of its causes and effects and the search for a cure. He movingly captures the disease’s impact on its victims and their families, and he looks back through history, explaining how Alzheimer’s most likely afflicted such figures as Jonathan Swift, Ralph Waldo Emerson,and William de Kooning. The result is a searing, powerfully engaging account of Alzheimer’s disease, offering a grim but sympathetic and ultimately encouraging portrait.

    Bruce Knecht, former reporter for The Wall Street Journal and author of The Proving Ground and Hooked, describes the creation of an outsized yacht in a sweeping narrative centered on the men and women who made it happen. DOUG VON ALLMEN, a self-made man who grew up in a landlocked state dreaming of the ocean, was poised to build a 187-foot yacht that would cost $40 million. Lady Linda would not be among the very largest of the burgeoning fleet of oceangoing palaces, but Von Allmen vowed that it would be the best one ever made in the United States. Nothing would be ordinary. The interior walls would be made from rare species of burl wood, the floors paved with onyx and exotic types of marble, the furniture custom made, and the art specially commissioned. But the 2008 economic crisis changed everything. Von Allmen’s lifestyle suddenly became unaffordable. Then it got worse: desperate to reverse his losses, he fell for an audacious Ponzi scheme. Would Von Allmen be able to complete Lady Linda? Would the shipyard and its one thousand employees survive the financial meltdown? The divide between the very rich and everyone else had never been greater, yet the livelihoods of the workers, some of them illegal immigrants, and the yacht owners were inextricably intertwined. In a sweeping, high-stakes narrative, the critically acclaimed author of The Proving Ground and Hooked weaves Von Allmen’s story together with those of the men and women who are building his yacht. As the pursuit of opulence collides with the reality of economic decline, everyone involved in the massive project is forced to rethink the meaning of the American Dream.

    Illnesses such as influenza, diabetes, multiple sclerosis, and coronary heart disease have also been connected to a lack of this vitamin. Until not too long ago, not getting enough Vitamin D (the sunshine vitamin) was only associated with rickets, the childhood bone disease. Now, Soram Khalsa, M.D., sheds new light on the power of this long-forgotten vitamin. He reveals how to recognize signs of Vitamin D deficiency, which has reached epidemic proportions in North America, and then shares insights from his Beverly Hills medical practice, where he normalizes his own patients’ Vitamin D levels for their optimal health.

    This illustrated handbook escorts you through the steps of the brewing process and offers a unique curriculum that supports and enhances your knowledge of brewing basics.Inside, you'll find:- 18 world-class brewers, including Vinnie Cilurzo (Russian River), Sam Calagione (Dogfish Head) and Ken Grossman (Sierra Nevada) as they share their expertise in vivid, engaging interviews- Advice on sourcing the best hops, barley, wheat, and more; farm-to-table and seasonal brewing- Strategies for setting up your homebrewing workshop to master brewing chemistry 101- Methods for tinkering with nontraditional ingredients and extreme brews- Techniques for brewing mead, sour ales, and cider

    Pulitzer Prize–winning author Siddhartha Mukherjee, a leading cancer physician and researcher, selects the year’s top science and nature writing from journalists who dive into their fields with curiosity and passion, delivering must-read articles from a wide array of fields.

    Deliberately hiding from the outside world, they are the unconquered, the last survivors of an ancient culture that predates the arrival of Columbus in the New World.  In this gripping first-person account of adventure and survival, author Scott Wallace chronicles an expedition into the Amazon’s uncharted depths, discovering the rainforest’s secrets while moving ever closer to a possible encounter with one such tribe—the mysterious flecheiros, or “People of the Arrow,” seldom-glimpsed warriors known to repulse all intruders with showers of deadly arrows. On assignment for National Geographic, Wallace joins Brazilian explorer Sydney Possuelo at the head of a thirty-four-man team that ventures deep into the unknown in search of the tribe. Possuelo’s mission is to protect the Arrow People. But the information he needs to do so can only be gleaned by entering a world of permanent twilight beneath the forest canopy.Danger lurks at every step as the expedition seeks out the Arrow People even while trying to avoid them. Along the way, Wallace uncovers clues as to who the Arrow People might be, how they have managed to endure as one of the last unconquered tribes, and why so much about them must remain shrouded in mystery if they are to survive. Laced with lessons from anthropology and the Amazon’s own convulsed history, and boasting a Conradian cast of unforgettable characters—all driven by a passion to preserve the wild, but also wracked by fear, suspicion, and the desperate need to make it home alive—The Unconquered reveals this critical battleground in the fight to save the planet as it has rarely been seen, wrapped in a page-turning tale of adventure.