Indeed, these tiny structures inside our cells are important beyond imagining. Without mitochondria, we would have no cell suicide, no sculpting of embryonic shape, no sexes, no menopause, no aging.In this fascinating and thought-provoking book, Nick Lane brings together the latest research in this exciting field to show how our growing insight into mitochondria has shed light on how complex life evolved, why sex arose (why don't we just bud?), and why we age and die. These findings are of fundamental importance, both in understanding life on Earth, but also in controlling our own illnesses, and delaying our degeneration and death. Readers learn that two billion years ago, mitochondria were probably bacteria living independent lives and that their capture within larger cells was a turning point in the evolution of life, enabling the development of complex organisms. Lane describes how mitochondria have their own DNA and that its genes mutate much faster than those in the nucleus. This high mutation rate lies behind our aging and certain congenital diseases. The latest research suggests that mitochondria play a key role in degenerative diseases such as cancer. We also discover that mitochondrial DNA is passed down almost exclusively via the female line. That's why it has been used by some researchers to trace human ancestry daughter-to-mother, to "Mitochondrial Eve," giving us vital information about our evolutionary history.Written by Nick Lane, a rising star in popular science, Power, Sex, Suicide is the first book for general readers on the nature and function of these tiny, yet fascinating structures.

    Gut, an international bestseller, gives the alimentary canal its long-overdue moment in the spotlight. With quirky charm, rising science star Giulia Enders explains the gut’s magic, answering questions like: Why does acid reflux happen? What’s really up with gluten and lactose intolerance? How does the gut affect obesity and mood? Communication between the gut and the brain is one of the fastest-growing areas of medical research—on par with stem-cell research. Our gut reactions, we learn, are intimately connected with our physical and mental well-being. Enders’s beguiling manifesto will make you finally listen to those butterflies in your stomach: they’re trying to tell you something important.

    Hayes describes it with more depth and clarity than ever before.-Mark Manson, #1 New York Times best-selling author of The Subtle Art of Not Giving a F*ck Life is not a problem to be solved. ACT shows how we can live full and meaningful lives by embracing our vulnerability and turning toward what hurts. In this landmark book, the originator and pioneering researcher into Acceptance and Commitment Therapy (ACT) lays out the psychological flexibility skills that make it one of the most powerful approaches research has yet to offer. These skills have been shown to help even where other approaches have failed. Science shows that they are useful in virtually every area--mental health (anxiety, depression, substance abuse, eating disorders, PTSD); physical health (chronic pain, dealing with diabetes, facing cancer); social processes (relationship issues, prejudice, stigma, domestic violence); and performance (sports, business, diet, exercise).How does psychological flexibility help? We struggle because the problem-solving mind tells us to run from what causes us fear and hurt. But we hurt where we care. If we run from a sense of vulnerability, we must also run from what we care about. By learning how to liberate ourselves, we can live with meaning and purpose, along with our pain when there is pain.Although that is a simple idea, it resists our instincts and programming. The flexibility skills counter those ingrained tendencies. They include noticing our thoughts with curiosity, opening to our emotions, attending to what is in the present, learning the art of perspective taking, discovering our deepest values, and building habits based around what we deeply want.Beginning with the epiphany Steven Hayes had during a panic attack, this book is a powerful narrative of scientific discovery filled with moving stories as well as advice for how we can put flexibility skills to work immediately. Hayes shows how allowing ourselves to feel fully and think freely moves us toward commitment to what truly matters to us. Finally, we can live lives that reflect the qualities we choose.

    But in the inevitable condition of aging and death, the goals of medicine seem too frequently to run counter to the interest of the human spirit. Nursing homes, preoccupied with safety, pin patients into railed beds and wheelchairs. Hospitals isolate the dying, checking for vital signs long after the goals of cure have become moot. Doctors, committed to extending life, continue to carry out devastating procedures that in the end extend suffering.Gawande, a practicing surgeon, addresses his profession's ultimate limitation, arguing that quality of life is the desired goal for patients and families. Gawande offers examples of freer, more socially fulfilling models for assisting the infirm and dependent elderly, and he explores the varieties of hospice care to demonstrate that a person's last weeks or months may be rich and dignified.

    He offers compelling evidence that religious experiences have a nonmaterial origin, making a convincing case for what many in scientific fields are loath to consider—that it is God who creates our spiritual experiences, not the brain.Beauregard and O'Leary explore recent attempts to locate a "God gene" in some of us and claims that our brains are "hardwired" for religion—even the strange case of one neuroscientist who allegedly invented an electromagnetic "God helmet" that could produce a mystical experience in anyone who wore it. The authors argue that these attempts are misguided and narrow-minded, because they reduce spiritual experiences to material phenomena.Many scientists ignore hard evidence that challenges their materialistic prejudice, clinging to the limited view that our experiences are explainable only by material causes, in the obstinate conviction that the physical world is the only reality. But scientific materialism is at a loss to explain irrefutable accounts of mind over matter, of intuition, willpower, and leaps of faith, of the "placebo effect" in medicine, of near-death experiences on the operating table, and of psychic premonitions of a loved one in crisis, to say nothing of the occasional sense of oneness with nature and mystical experiences in meditation or prayer. Traditional science explains away these and other occurrences as delusions or misunderstandings, but by exploring the latest neurological research on phenomena such as these, The Spiritual Brain gets to their real source.

    Research psychologist Sonja Lyubomirsky's pioneering concept of the 40% solution shows you how Drawing on her own groundbreaking research with thousands of men and women, research psychologist and University of California professor of psychology Sonja Lyubomirsky has pioneered a detailed yet easy-to-follow plan to increase happiness in our day-to-day lives-in the short term and over the long term. The How of Happiness is a different kind of happiness book, one that offers a comprehensive guide to understanding what happiness is, and isn't, and what can be done to bring us all closer to the happy life we envision for ourselves. Using more than a dozen uniquely formulated happiness-increasing strategies, The How of Happiness offers a new and potentially life- changing way to understand our innate potential for joy and happiness as well as our ability to sustain it in our lives. Beginning with a short diagnostic quiz that helps readers to first quantify and then to understand what she describes as their "happiness set point," Lyubomirsky reveals that this set point determines just 50 percent of happiness while a mere 10 percent can be attributed to differences in life circumstances or situations. This leaves a startling, and startlingly underdeveloped, 40 percent of our capacity for happiness within our power to change. Lyubomirsky's "happiness strategies" introduce readers to the concept of intentional activities, mindful actions that they can use to achieve a happier life. These include exercises in practicing optimism when imagining the future, instruction in how best to savor life's pleasures in the here and now, and a thoroughgoing explanation of the importance of staying active to being happy. Helping readers find the right fit between the goals they set and the activities she suggests, Lyubomirsky also helps readers understand the many obstacles to happiness as well as how to harness individual strengths to overcome them. Always emphasizing how much of our happiness is within our control, Lyubomirsky addresses the "scientific how" of her happiness research, demystifying the many myths that unnecessarily complicate its pursuit. Unlike those of many self-help books, all her recommendations are supported by scientific research. The How of Happiness is both a powerful contribution to the field of positive psychology and a gift to all those who have questioned their own well- being and sought to take their happiness into their own hands.

    Author Dr. Bruce Lipton is a former medical school professor and research scientist. His experiments, and that of other leading-edge scientists, have examined in great detail the processes by which cells receive information. The implications of this research radically change our understanding of life. It shows that genes and DNA do not control our biology; that instead DNA is controlled by signals from outside the cell, including the energetic messages emanating from our positive and negative thoughts. Dr. Lipton's profoundly hopeful synthesis of the latest and best research in cell biology and quantum physics is being hailed as a major breakthrough showing that our bodies can be changed as we retrain our thinking.

     "A riveting and absolutely fascinating adventure that will blow your mind wide open!" --Dr. Rudolph E. Tanzi What happens when modern science reaches a crucial turning point that challenges everything we know about reality? In this brilliant, timely, and practical work, Chopra and Kafatos tell us that we've reached just such a point. In the coming era, the universe will be completely redefined as a "human universe" radically unlike the cold, empty void where human life is barely a speck in the cosmos.You Are the Universe literally means what it says--each of us is a co-creator of reality extending to the vastest reaches of time and space. This seemingly impossible proposition follows from the current state of science, where outside the public eye, some key mysteries cannot be solved, even though they are the very issues that define reality itself:- What Came Before the Big Bang?- Why Does the Universe Fit Together So Perfectly?- Where Did Time Come From?- What Is the Universe Made Of?- Is the Quantum World Linked to Everyday Life?- Do We Live in a Conscious Universe?- How Did Life First Begin?"The shift into a new paradigm is happening," the authors write. "The answers offered in this book are not our invention or eccentric flights of fancy. All of us live in a participatory universe. Once you decide that you want to participate fully with mind, body, and soul, the paradigm shift becomes personal. The reality you inhabit will be yours either to embrace or to change." What these two great minds offer is a bold, new understanding of who we are and how we can transform the world for the better while reaching our greatest potential.

    Mirroring his theory, Minsky boldly casts The Society of Mind as an intellectual puzzle whose pieces are assembled along the way. Each chapter -- on a self-contained page -- corresponds to a piece in the puzzle. As the pages turn, a unified theory of the mind emerges, like a mosaic. Ingenious, amusing, and easy to read, The Society of Mind is an adventure in imagination.

    (The somewhat confusing title is from a line in Zorba the Greek in which the title character refers to the ups and downs of family life as "the full catastrophe.") But this book is also a terrific introduction for anyone who has considered meditating but was afraid it would be too difficult or would include religious practices they found foreign. Kabat-Zinn focuses on "mindfulness," a concept that involves living in the moment, paying attention, and simply "being" rather than "doing." While you can practice anything "mindfully," from taking a walk to cleaning your house, Kabat-Zinn presents several meditation techniques that focus the attention most clearly, whether it's on a simple phrase, your breathing, or various parts of your body. The book goes into detail about how hospital patients have either improved their health or simply come to feel better despite their illness by using these techniques, but these meditations can help anyone deal with stress and gain a calmer outlook on life. "When we use the word healing to describe the experiences of people in the stress clinic, what we mean above all is that they are undergoing a profound transformation of view," Kabat-Zinn writes. "Out of this shift in perspective comes an ability to act with greater balance and inner security in the world." --Ben Kallenreissue 2005

    Henry Emmons offers a proven plan to combat anxiety—without medication—that has helped tens of thousands gain inner peace and start enjoying life. The debilitating effects of anxiety can affect your sense of well-being, health, longevity, productivity, and relationships. In The Chemistry of Calm, Dr. Henry Emmons presents his Resilience Training Program—a groundbreaking regimen designed to relieve anxiety and restore physical and mental strength. This step-by-step plan for mental calmness and emotional wisdom focuses on ways to create resilience as a key to resolving anxiety in everyday life, incorporating the latest science on: -Diet—you’ve got to eat good food to feel good -Exercise—it’s proven: moving makes you less anxious -Nutritional Supplements—boosting your natural anxiety resistance -Mindfulness—including meditation techniques to calm your body and brain Using this program, Dr. Emmons has helped countless patients reduce their anxiety and reclaim the resilience that is their birthright. Now, with The Chemistry of Calm, you can be anxiety free too!

    These “psychosurgeons,” as they called themselves, occupied a gray zone between medical research and medical practice, and ended up subjecting untold numbers of people to the types of surgical experiments once limited to chimpanzees.The most important test subject to emerge from this largely untold chapter in American history was a twenty-seven-year-old factory worker named Henry Molaison. In 1953, Henry—who suffered from severe epilepsy—received a radical new version of the lobotomy, one that targeted the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry left the operating room profoundly amnesic, unable to create new long-term memories. Over the next sixty years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.Luke Dittrich uses the case of Patient H.M. as a starting point for a kaleidoscopic journey, one that moves from the first recorded brain surgeries in ancient Egypt to the cutting-edge laboratories of MIT. He takes readers inside the old asylums and operating theaters where psychosurgeons conducted their human experiments, and behind the scenes of a bitter custody battle over the ownership of the most important brain in the world. Throughout, Dittrich delves into the enduring mysteries of the mind while exposing troubling stories of just how far we’ve gone in our pursuit of knowledge. It is also, at times, a deeply personal journey. Dittrich’s grandfather was the brilliant, morally complex surgeon who operated on Molaison—and thousands of other patients. The author’s investigation into the dark roots of modern memory science ultimately forces him to confront unsettling secrets in his own family history, and to reveal the tragedy that fueled his grandfather’s relentless experimentation—experimentation that would revolutionize our understanding of ourselves.Patient H.M. combines the best of biography, memoir, and science journalism to create a haunting, endlessly fascinating story, one that reveals the wondrous and devastating things that can happen when hubris, ambition, and human imperfection collide.

    Other bestselling works of neurobiology and the mind have focused on mental illness and abnormal behaviors—like the Oliver Sacks classic, The Man Who Mistook His Wife for a Hat—but The Other Side of Normal is an eye-opening, thought-provoking, utterly fascinating and totally accessible exploration of the universals of human experience. It will change forever our understanding of who we are and what makes us that way.

    Twenty-five centuries later, humans have transformed everything about our world—except our brains, which remain the same powerful yet flawed instruments possessed by our ancestors. What if the solution we seek to the psychological problems of life in the digital age—distraction, anxiety, addiction, loss of deep meaning—had already been worked out by the Buddha in ancient India? Appealing to readers of Eastern wisdom and Jon Kabat-Zinn, as well as to fans of bestsellers by Oliver Sacks and Malcolm Gladwell, acclaimed science writer and practicing Buddhist James Kingsland reveals how scientists are now unlocking the remarkable secrets of Siddhartha’s brain.Moving effortlessly between science and scripture, Kingsland charts Siddhartha’s spiritual journey and explains how new research by leading neuroscientists and clinical psychologists—many of whom are interviewed in these pages—suggests that mindfulness practice reconfigures our brains to make us sharper, smarter, healthier, and happier, and that it can help treat stress, anxiety, depression, chronic pain, hypertension, and substance abuse. There have even been hints that meditation can enhance immune function, slow cellular aging, and keep dementia at bay. Featuring six guided meditations, Siddhartha’s Brain is a practical and inspiring odyssey of mind and spirit.“Our life is shaped by our mind; we become what we think.”—Siddhartha

    It is, in other words, the key to reshaping our very lives.”―Oprah WinfreyThis book is going to change the way you see your life.Have you ever wondered "Why did I do that?" or "Why can't I just control my behavior?" Others may judge our reactions and think, "What's wrong with that person?" When questioning our emotions, it's easy to place the blame on ourselves; holding ourselves and those around us to an impossible standard. It's time we started asking a different question.Through deeply personal conversations, Oprah Winfrey and renowned brain and trauma expert Dr. Bruce Perry offer a groundbreaking and profound shift from asking “What’s wrong with you?” to “What happened to you?” Our earliest experiences shape our lives far down the road, and What Happened to You? provides powerful scientific and emotional insights into the behavioral patterns so many of us struggle to understand.Here, Winfrey shares stories from her own past, understanding through experience the vulnerability that comes from facing trauma and adversity at a young age. Joining forces with Dr. Perry, one of the world’s leading experts on childhood and brain development, Winfrey and Dr. Perry marry the power of storytelling with science to better understand and overcome the effects of our pasts.In conversation throughout the book, the two focus on understanding people, behavior, and ourselves. It’s a subtle but profound shift in our approach to trauma, and it’s one that allows us to understand our pasts in order to clear a path to our future―opening the door to resilience and healing in a proven, powerful way.