“This is Steve Jobs. I saw your picture in a magazine a few years ago and thought we’d work together someday.” After Steve Jobs was unceremoniously dismissed from Apple, he bought a little-known graphics company called Pixar. One day, out of the blue, Jobs called Lawrence Levy, a Harvard-trained lawyer and executive to whom he had never spoken before, to persuade Levy to help him get Pixar off the ground. What Levy found was a company on the verge of failure. To Pixar and Beyond is the story of what happened next: how, working closely with Jobs, Levy produced and implemented a highly improbable plan that transformed Pixar into one of Hollywood’s greatest success stories. Set in the worlds of Silicon Valley and Hollywood, the book takes readers inside Pixar, Disney, law firms, and investment banks. It provides an up-close, firsthand account of Pixar’s ascent, how it made creative choices, Levy’s enduring collaboration and friendship with Jobs, and how Levy came to see in Pixar deeper lessons that can apply to many aspects of our lives.

    Brian Arthur puts forth the first complete theory of the origins and evolution of technology, in a major work that achieves for the invention of new technologies what Darwin’s theory achieved for the emergence of new species. Brian Arthur is a pioneer of complexity theory and the discoverer of the highly influential "theory of increasing returns," which took Silicon Valley by storm, famously explaining why some high-tech companies achieve breakaway success. Now, in this long-awaited and ground-breaking book, he solves the great outstanding puzzle of technology—where do transformative new technologies come from?—putting forth the first full theory of how new technologies emerge and offering a definitive answer to the mystery of why some cultures—Silicon Valley, Cambridge, England in the 1920s—are so extraordinarily inventive. He has discovered that rather than springing from insight moments of individual genius, new technologies arise in a process akin to evolution. Technology evolves by creating itself out of itself, much as a coral reef builds itself from activities of small organisms. Drawing on a wealth of examples, from the most ancient to cutting-edge inventions of today, Arthur takes readers on a delightful intellectual journey, bringing to life the wonders of this process of technological evolution. The Nature of Technology is the work of one of our greatest thinkers at the top of his game, composing a classic for our times that is sure to generate wide acclaim.

    It draws on all the latest knowledge from anthropology and archaeology, via genetics and evolution, to psychology and medicine. It tackles issues such as hereditary genes in criminal behaviour and homosexuality.

    With the help of visionary businessman Steve Jobs and animating genius John Lasseter, Pixar has become the gold standard of animated filmmaking, beginning with a short special effects shot made at Lucasfilm in 1982 all the way up through the landmark films Toy Story, Finding Nemo, Wall-E, and others. David A. Price goes behind the scenes of the corporate feuds between Lasseter and his former champion, Jeffrey Katzenberg, as well as between Steve Jobs and Michael Eisner. And finally he explores Pixar's complex relationship with the Walt Disney Company as it transformed itself into the $7.4 billion jewel in the Disney crown.

    In June 1962, a young biologist in Philadelphia, using tissue extracted from an aborted fetus from Sweden, produced safe, clean cells that allowed the creation of vaccines against rubella and other common childhood diseases. Two years later, in the midst of a devastating German measles epidemic, his colleague developed the vaccine that would one day wipe out homegrown rubella. The rubella vaccine and others made with those fetal cells have protected more than 150 million people in the United States, the vast majority of them preschoolers. The new cells and the method of making them also led to vaccines that have protected billions of people around the world from polio, rabies, chicken pox, measles, hepatitis A, shingles and adenovirus. Meredith Wadman’s masterful account recovers not only the science of this urgent race, but also the political roadblocks that nearly stopped the scientists. She describes the terrible dilemmas of pregnant women exposed to German measles and recounts testing on infants, prisoners, orphans, and the intellectually disabled, which was common in the era. These events take place at the dawn of the battle over using human fetal tissue in research, during the arrival of big commerce in campus labs, and as huge changes take place in the laws and practices governing who “owns” research cells and the profits made from biological inventions. It is also the story of yet one more unrecognized woman whose cells have been used to save countless lives. With another frightening virus imperiling pregnant women on the rise today, no medical story could have more human drama, impact, or urgency today than The Vaccine Race.

    There she saw first-hand how deeply intertwined Silicon Valley was with the federal government, and always had been, and how shallow the common understanding of the secrets of the Valley's success actually was. Now, after almost five years of pioneering research, O'Mara has produced the definitive history of Silicon Valley for our time, the story of mavericks and visionaries, but also of powerful institutions creating the framework for innovation, from the Pentagon to Stanford University. It is also a story of a community that started off remarkably homogeneous and elitist and stayed that way, and whose belief in its own mythology has deepened into a collective hubris that has led to astonishing triumphs as well as devastating second-order effects.Deploying a wonderfully rich and diverse cast of protagonists, from the justly famous to the unjustly obscure, across four generations of explosive growth in the Valley, from the Forties to the present, O'Mara has wrestled into magnificent narrative form one of the most fateful developments in modern American history. She is on the ground with all of the key tech companies, and chronicles the evolution in their offerings through each successive era, and she has a profound fingertip feel for the politics of the sector, and its relation to the larger cultural narrative about tech as it has evolved over the years. Perhaps most impressively, O'Mara has penetrated the inner kingdom of tech venture capital firms, the insular and still remarkably old-boy world that became the cockpit of American capitalism and the crucible for bringing technological innovation to market, or not. The transformation of big tech into the engine room of the American economy and the nexus of so many of our hopes and dreams--and increasingly nightmares--can be understood, in Margaret O'Mara's masterful hands, as the story of one California valley. As her majestic history makes clear, its fate is the fate of us all.

    She spent ten years training and working as an Anatomical Pathology Technologist: where the mortuary slab was her desk, and that day's corpses her task list.Past Mortems tells Carla's stories of those years, as well as investigating the body alongside our attitudes towards death - shedding light on what the living can learn from dead and the toll the work can take on the living souls who carry it out. Fascinating and insightful, Past Mortems reveals the truth about what happens when the mortuary doors swing shut or the lid of the coffin closes . . .

    Martin A. Lee traces the dramatic social history of marijuana from its origins to its emergence in the 1960s as a defining force in a culture war that has never ceased. Lee describes how the illicit marijuana subculture overcame government opposition and morphed into a dynamic, multibillion-dollar industry. In 1996, California voters approved Proposition 215, legalizing marijuana for medicinal purposes. Similar laws have followed in more than a dozen other states, but not without antagonistic responses from federal, state, and local law enforcement. Lee, an award-winning investigative journalist, draws attention to underreported scientific breakthroughs that are reshaping the therapeutic landscape. By mining the plant’s rich pharmacopoeia, medical researchers have developed promising treatments for cancer, heart disease, Alzheimer’s, diabetes, chronic pain, and many other conditions that are beyond the reach of conventional cures.Colorful, illuminating, and at times irreverent, this is a fascinating read for recreational users and patients, students and doctors, musicians and accountants, Baby Boomers and their kids, and anyone who has ever wondered about the secret life of this ubiquitous herb. Smoke Signals is the winner of the American Botanical Council's James A. Duke Excellence in Botanical Literature Award for 2012

    In all the current highly publicized debates about creationism and its descendant "intelligent design," there is an element of the controversy that is rarely mentioned—the "evidence," the empirical truth of evolution by natural selection. Even Richard Dawkins and Stephen Jay Gould, while extolling the beauty of evolution and examining case studies, have not focused on the evidence itself. Yet the proof is vast, varied, and magnificent, drawn from many different fields of science. Scientists are observing species splitting into two and are finding more and more fossils capturing change in the past—dinosaurs that have sprouted feathers, fish that have grown limbs. Why Evolution Is True weaves together the many threads of modern work in genetics, paleontology, geology, molecular biology, and anatomy that demonstrate the "indelible stamp" of the processes first proposed by Darwin. In crisp, lucid prose accessible to a wide audience, Why Evolution Is True dispels common misunderstandings and fears about evolution and clearly confirms that this amazing process of change has been firmly established as a scientific truth.

    She conjures up early operating theaters--no place for the squeamish--and surgeons, working before anesthesia, who were lauded for their speed and brute strength. These medical pioneers knew that the aftermath of surgery was often more dangerous than their patients' afflictions, and they were baffled by the persistent infections that kept mortality rates stubbornly high. At a time when surgery couldn't have been more hazardous, an unlikely figure stepped forward: a young, melancholy Quaker surgeon named Joseph Lister, who would solve the deadly riddle and change the course of history.Fitzharris dramatically recounts Lister's discoveries in gripping detail, culminating in his audacious claim that germs were the source of all infection--and could be countered by antiseptics. Focusing on the tumultuous period from 1850 to 1875, she introduces us to Lister and his contemporaries--some of them brilliant, some outright criminal--and takes us through the grimy medical schools and dreary hospitals where they learned their art, the deadhouses where they studied anatomy, and the graveyards they occasionally ransacked for cadavers.Eerie and illuminating, The Butchering Art celebrates the triumph of a visionary surgeon whose quest to unite science and medicine delivered us into the modern world.

    Less than 20 years after its founding, it boasts the largest constellation of commercial satellites in orbit, has pioneered reusable rockets, and in 2020 became the first private company to launch human beings into orbit. Half a century after the space race it is private companies, led by SpaceX, standing alongside NASA pushing forward into the cosmos, and laying the foundation for our exploration of other worlds.But before it became one of the most powerful players in the aerospace industry, SpaceX was a fledgling startup, scrambling to develop a single workable rocket before the money ran dry. The engineering challenge was immense; numerous other private companies had failed similar attempts. And even if SpaceX succeeded, they would then have to compete for government contracts with titans such as Lockheed Martin and Boeing, who had tens of thousands of employees and tens of billions of dollars in annual revenue. SpaceX had fewer than 200 employees and the relative pittance of $100 million in the bank.In Liftoff, Eric Berger, senior space editor at Ars Technica, takes readers inside the wild early days that made SpaceX. Focusing on the company’s first four launches of the Falcon 1 rocket, he charts the bumpy journey from scrappy underdog to aerospace pioneer. We travel from company headquarters in El Segundo, to the isolated Texas ranchland where they performed engine tests, to Kwajalein, the tiny atoll in the Pacific where SpaceX launched the Falcon 1. Berger has reported on SpaceX for more than a decade, enjoying unparalleled journalistic access to the company’s inner workings. Liftoff is the culmination of these efforts, drawing upon exclusive interviews with dozens of former and current engineers, designers, mechanics, and executives, including Elon Musk. The enigmatic Musk, who founded the company with the dream of one day settling Mars, is the fuel that propels the book, with his daring vision for the future of space.Filled with never-before-told stories of SpaceX’s turbulent beginning, Liftoff is a saga of cosmic proportions.

    Smallpox. Incurable and horrifying Ebola-related fevers. For two decades, while a fearful world prepared for nuclear winter, an elite team of Russian bioweaponeers began to till a new killing field: a bleak tract sown with powerful seeds of mass destruction—by doctors who had committed themselves to creating a biological Armageddon. Biohazard is the never-before-told story of Russia’s darkest, deadliest, and most closely guarded Cold War secret.   No one knows more about Russia’s astounding experiments with biowarfare than Ken Alibek. Now the mastermind behind Russia’s germ warfare effort reveals two decades of shocking breakthroughs . . . how Moscow’s leading scientists actually reengineered hazardous microbes to make them even more virulent . . . the secrets behind the discovery of an invisible, untraceable new class of biological agents just right for use in political assassinations . . . the startling story behind Russia’s attempt to turn a sample of the AIDS virus into the ultimate bioweapon. And in a chilling work of real-world intrigue, Biohazard offers us all a rare glimpse into a shadowy scientific underworld where doctors manufacture mass destruction, where witnesses to errors are silenced forever, and where ground zero is closer than we ever dared believe.

    Armed with a healthy dose of wit and curiosity, medical journalist Randi Hutter Epstein reveals the “invigorating history” (Nature) of hormones and the age-old quest to control them through the back rooms, basements, and labs where endocrinology began.

    Even before he won the Nobel Prize in 1965, his unorthodox and spellbinding lectures on physics secured his reputation amongst students and seekers around the world. It was his outsized love for life, however, that earned him the status of an American cultural icon - here was an extraordinary intellect devoted to the proposition that the thrill of discovery was matched only by the joy of communicating it to others." In this career-spanning collection of letters, many published here for the first time, we are able to see this side of Feynman like never before. Perfectly Reasonable Deviations from the Beaten Track covers a dazzling array of topics and themes, scientific developments and personal histories. With missives to and from scientific luminaries, as well as letters to and from fans, family, students, crackpots, as well as everyday people eager for Feynman's wisdom and counsel, the result is a de facto guide to life, and eloquent testimony to the human quest for knowledge at all levels.Published in the UK as Don't You Have Time to Think?

    In Dyson's view, science and religion are two windows through which we can look out at the world around us. The book is a revised version of a series of the Gifford Lectures under the title "In Praise of Diversity" given at Aberdeen, Scotland. They allowed Dyson the license to express everything in the universe, which he divided into two parts in polished prose: focusing on the diversity of the natural world as the first, and the diversity of human reactions as the second half.Chapter 1 is a brief explanation of Dyson's attitudes toward religion and science. Chapter 2 is a one–hour tour of the universe that emphasizes the diversity of viewpoints from which the universe can be encountered as well as the diversity of objects which it contains. Chapter 3 is concerned with the history of science and describes two contrasting styles in science: one welcoming diversity and the other deploring it. He uses the cities of Manchester and Athens as symbols of these two ways of approaching science. Chapter 4, concerned with the origin of life, describes the ideas of six illustrious scientists who have struggled to understand the nature of life from various points of view. Chapter 5 continues the discussion of the nature and evolution of life. The question of why life characteristically tends toward extremes of diversity remains central in all attempts to understand life's place in the universe. Chapter 6 is an exercise in eschatology, trying to define possible futures for life and for the universe, from here to infinity. In this chapter, Dyson crosses the border between science and science fiction and he frames his speculations in a slightly theological context.