The Human Genome Project finished sequencing human DNA. It seemed it was only a matter of time until we had all the answers to the secrets of life on this planet. The cutting-edge of biology, however, is telling us that we still don't even know all of the questions. How is it that, despite each cell in your body carrying exactly the same DNA, you don't have teeth growing out of your eyeballs or toenails on your liver? How is it that identical twins share exactly the same DNA and yet can exhibit dramatic differences in the way that they live and grow? It turns out that cells read the genetic code in DNA more like a script to be interpreted than a mould that replicates the same result each time. This is epigenetics and it's the fastest-moving field in biology today. The Epigenetics Revolution traces the thrilling path this discipline has taken over the last twenty years. Biologist Nessa Carey deftly explains such diverse phenomena as how queen bees and ants control their colonies, why tortoiseshell cats are always female, why some plants need a period of cold before they can flower, why we age, develop disease and become addicted to drugs, and much more. Most excitingly, Carey reveals the amazing possibilities for humankind that epigenetics offers for us all - and in the surprisingly near future.

    Throughout our life, we look for ways to keep our mind sharp and effortlessly productive. Now, globetrotting neurosurgeon Dr. Sanjay Gupta offers insights from top scientists all over the world, whose cutting-edge research can help you heighten and protect brain function and maintain cognitive health at any age. Keep Sharp debunks common myths about aging and cognitive decline, explores whether there’s a “best” diet or exercise regimen for the brain, and explains whether it’s healthier to play video games that test memory and processing speed, or to engage in more social interaction. Discover what we can learn from “super-brained” people who are in their eighties and nineties with no signs of slowing down—and whether there are truly any benefits to drugs, supplements, and vitamins. Dr. Gupta also addresses brain disease, particularly Alzheimer’s, answers all your questions about the signs and symptoms, and shows how to ward against it and stay healthy while caring for a partner in cognitive decline. He likewise provides you with a personalized twelve-week program featuring practical strategies to strengthen your brain every day. Keep Sharp is the only owner’s manual you’ll need to keep your brain young and healthy regardless of your age!

    Departing from the South Bronx and turning his sensitive eye to his own life and legacy, The Theft of Memory is Kozol's most personal book to date, as it explores the life of his father, Harry. Dr. Harry L. Kozol was a nationally-renowned neurologist whose work helped establish the emerging fields of forensic psychiatry and neuropsychiatry. He was a remarkable clinician with unusual capacity to diagnose and identify neurological and psychotic illnesses in highly complicated and sophisticated people, including well-known artists, writers, and intellectuals. Notably, in Eugene O'Neill's last years, the playwright moved to Boston so that he could live close to Kozol's father's office.In addition to his successful private practice in Boston, Kozol operated in a grim arena marked by extreme violence. But while his role as a forensic expert placed him in the public eye for high-profile criminal defendants such as Albert DeSalvo (the Boston Strangler) and Patty Hearst, he was--as his son articulates--"a healer of tormented people, not their judge, not their interrogator."With the same lyricism and clarity that have defined Kozol's acclaimed work on education for decades,The Theft of Memory intimately describes Harry's vibrant life, the challenges following his self-diagnosis of Alzheimer's, and the evolution of their relationship throughout.This unique biography will have a long shelf life as a moving portrait of an extraordinary man, a window into the heart of one of our nation's foremost education activists, and a frank examination of how we come to terms with caregiving.

    Every new reader's brain possesses the extraordinary capacity to rearrange itself beyond its original abilities in order to understand written symbols. But how does the brain learn to read? As world-renowned cognitive neuroscientist and scholar of reading Maryanne Wolf explains in this impassioned book, we taught our brain to read only a few thousand years ago, and in the process changed the intellectual evolution of our species.Wolf tells us that the brain that examined tiny clay tablets in the cuneiform script of the Sumerians is configured differently from the brain that reads alphabets or of one literate in today's technology.There are critical implications to such an evolving brain. Just as writing reduced the need for memory, the proliferation of information and the particular requirements of digital culture may short-circuit some of written language's unique contributions—with potentially profound consequences for our future.Turning her attention to the development of the individual reading brain, Wolf draws on her expertise in dyslexia to investigate what happens when the brain finds it difficult to read. Interweaving her vast knowledge of neuroscience, psychology, literature, and linguistics, Wolf takes the reader from the brains of a pre-literate Homer to a literacy-ambivalent Plato, from an infant listening to Goodnight Moon to an expert reader of Proust, and finally to an often misunderstood child with dyslexia whose gifts may be as real as the challenges he or she faces.As we come to appreciate how the evolution and development of reading have changed the very arrangement of our brain and our intellectual life, we begin to realize with ever greater comprehension that we truly are what we read. Ambitious, provocative, and rich with examples, Proust and the Squid celebrates reading, one of the single most remarkable inventions in history. Once embarked on this magnificent story of the reading brain, you will never again take for granted your ability to absorb the written word.

    With more than one in every five people over the age of fourteen addicted, drug abuse has been called the most formidable health problem worldwide. If we are not victims ourselves, we all know someone struggling with the merciless compulsion to alter their experience by changing how their brain functions.Drawing on years of research--as well as personal experience as a recovered addict--researcher and professor Judy Grisel has reached a fundamental conclusion: for the addict, there will never be enough drugs. The brain's capacity to learn and adapt is seemingly infinite, allowing it to counteract any regular disruption, including that caused by drugs. What begins as a normal state punctuated by periods of being high transforms over time into a state of desperate craving that is only temporarily subdued by a fix, explaining why addicts are unable to live either with or without their drug. One by one, Grisel shows how different drugs act on the brain, the kind of experiential effects they generate, and the specific reasons why each is so hard to kick.Grisel's insights lead to a better understanding of the brain's critical contributions to addictive behavior, and will help inform a more rational, coherent, and compassionate response to the epidemic in our homes and communities.

    You're not stuck with the brain you're born with. Here are just a few of neuropsychiatrist Dr. Daniel Amen's surprising--and effective--"brain prescriptions" that can help heal your brain and change your life:To Quell Anxiety and Panic: ¸  Use simple breathing techniques to immediately calm inner turmoilTo Fight Depression: ¸  Learn how to kill ANTs (automatic negative thoughts)To Curb Anger: ¸  Follow the Amen anti-anger diet and learn the nutrients that calm rageTo Conquer Impulsiveness and Learn to Focus: ¸  Develop total focus with the "One-Page Miracle"To Stop Obsessive Worrying: ¸  Follow the "get unstuck" writing exercise and learn other problem-solving exercises

    In 1828, when New York City purchased this narrow, two-mile-long island in the East River, it was called Blackwell’s Island. There, over the next hundred years, the city would send its insane, indigent, sick, and criminal. Told through the gripping voices of Blackwell’s inhabitants, as well as the period’s city officials, reformers, and journalists (including the famous Nellie Bly), Stacy Horn has crafted a compelling and chilling narrative.  Damnation Island recreates what daily life was like on the island, what politics shaped it, and what constituted charity and therapy in the nineteenth century. Throughout the book, we return to the extraordinary Blackwell’s missionary Reverend French, champion of the forgotten, as he ministers to these inmates, battles the bureaucratic mazes of the Corrections Department and a corrupt City Hall, testifies at salacious trials, and in his diary wonders about man’s inhumanity to man.   For history fans, and for anyone interested in the ways we care for the least fortunate among us, Damnation Island is an eye-opening look at a closed and secretive world. With a tale that is exceedingly relevant today, Horn shows us how far we’ve come—and how much work still remains.

    When she heard about the shooting at Sandy Hook Elementary School in Newtown, Connecticut, her first thought was, What if my son does that someday? She wrote an emotional response to the tragedy, which the Boise State University online journal posted as I Am Adam Lanza s Mother. The post went viral, receiving 1.2 million Facebook likes, nearly 17,000 tweets, and 30,000 emails.Now, in "The Price of Silence "she takes a devastating look at how we address mental illness, especially in children, who are funneled through a system of education, mental health care, and juvenile detention that leads far too often to prison. In the end she asks one central question: if there s a poster child for cancer, why can t there be one for mental illness? The answer: the stigma. Liza Long is speaking in a way that we cannot help but hear, and she won t stop until something changes."

    Most us have disturbed, restless nights and rely on a cocktail of caffeine and sugar to drag us through the day. Yet the hours we spend in bed shape our mood, motivation and decision-making skills - defining our performance in work, at home and keeping fit.We need a new approach to sleep. One that helps us cope with our ever more demanding days and always be our personal best.Nick Littlehales is the elite sleep coach to some of the world's leading sports stars and teams, across Premiership and international football, British Cycling and Team Sky, rugby and Olympic sports. His groundbreaking practical techniques have transformed the way athletes approach sleep, unlocking higher levels of mental and physical recovery, personal best performances and ultimately a winning mindset.Now he lays bare his strategies for us all to use. From your personal sleep characteristics and cycles, to posture and bedding, he sets out achievable ways to get the highest possible quality of sleep recovery.Read Sleep, learn from the best in sport, and kickstart a more confident, successful and happier you.

    In Missing Microbes, Dr. Martin Blaser invites us into the wilds of the human microbiome where for hundreds of thousands of years bacterial and human cells have existed in a peaceful symbiosis that is responsible for the health and equilibrium of our body. Now, this invisible eden is being irrevocably damaged by some of our most revered medical advances—antibiotics—threatening the extinction of our irreplaceable microbes with terrible health consequences. Taking us into both the lab and deep into the fields where these troubling effects can be witnessed firsthand, Blaser not only provides cutting edge evidence for the adverse effects of antibiotics, he tells us what we can do to avoid even more catastrophic health problems in the future. http://us.macmillan.com/missingmicrob...

    Indeed, the brain's power is being confirmed every day in new studies and research. But there is a brain we don't generally hear about, a brain we might not want to hear about…the "prima donna within."Exposing the mind's deceptions and exploring how the mind defends and glorifies the ego, Dr. Cordelia Fine illustrates the brain's tendency to self-delusion. Whether it be hindsight bias, wishful thinking, unrealistic optimism, or moral excuse-making, each of us has a slew of inborn mind-bugs and ordinary prejudices that prevent us from seeing the truth about the world and ourselves. With fascinating studies to support her arguments, Dr. Fine takes us on an insightful, rip-roaringly funny tour through the brain you never knew you had.

    Peter D'Adamo and Catherine Whitney reveal the simple secret to healthy, vigorous, and disease-free living: basing your diet on your blood type. If you've ever suspected that not everyone should eat the same thing or do the same exercise, you're right. In fact, what foods we absorb well and how our bodies handle stress differ with each blood type. Your blood type reflects your internal chemistry. It is the key that unlocks the mysteries of disease, longevity, fitness, and emotional strength. It determines your susceptibility to illness, the foods you should eat, and ways to avoid the most troubling health problems. In Eat Right 4 Your Type, Dr. D'Adamo draws on over fifteen years of research to reveal: - Which foods, spices, teas, and condiments help maintain optimal health and ideal weight - Which vitamins and supplements to emphasize or avoid - Whether your stress is relieved better through aerobics or meditation - Whether you should walk, swim or play tennis or golf as your mode of exercise - How knowing your blood type can help you avoid many common viruses and infections and fight back against life-threatening diseases - How to slow down the aging process by avoiding factors that cause rapid cell deterioration Whether your blood type is O, A, B, or AB, Eat Right 4 Your Type will help you design a total health program that's perfect for you. MORE THAN 7 MILLION COPIES SOLD WORLDWIDE!

    Lobster rolls containing no lobster at all. Extra-virgin olive oil that isn’t. Fake foods are in our supermarkets, our restaurants, and our kitchen cabinets. Award-winning food journalist and travel writer Larry Olmsted exposes this pervasive and dangerous fraud perpetrated on unsuspecting Americans.     Real Food/Fake Food brings readers into the unregulated food industry, revealing that this shocking deception extends from high-end foods like olive oil, wine, and Kobe beef to everyday staples such as coffee, honey, juice, and cheese. It’s a massive bait and switch where counterfeiting is rampant and where the consumer ultimately pays the price. But Olmsted does more than show us what foods to avoid. A bona fide gourmand, he travels to the sources of the real stuff, to help us recognize what to look for, eat, and savor: genuine Parmigiano-Reggiano from Italy, fresh-caught grouper from Florida, authentic port from Portugal. Real foods that are grown, raised, produced, and prepared with care by masters of their craft.   Part cautionary tale, part culinary crusade, Real Food/Fake Food is addictively readable, mouth-wateringly enjoyable, and utterly relevant. Larry Olmsted convinces us why real food matters.

    Dr. Wilson explains that healthy functioning of your adrenal glands is essential to virtually all aspects of your health as well as to your ability to handle stress. For this reason, stress and adrenal function often also play a role in many health conditions, such as frequent infections, chemical sensitivities, allergies, autoimmune diseases like fibromyalgia and rheumatoid arthritis, menopause and PMS, thyroid function imbalances, chronic fatigue syndrome, low libido, chronic anxiety, and mild depression. All of these problems and more may be aggravated by the effects stress can have on your adrenal glands.Under certain circumstances, stress can fatigue your adrenals. It is estimated that most North Americans experience some form of stress-related adrenal fatigue at some time. Although many people realize that stress is a problem in their lives, few understand the actual physical ways stress acts on the body and mind through the adrenal glands – or more importantly, what to do about it. Unfortunately, even most doctors still do not recognize the common health picture produced by adrenal fatigue. This leaves a lot of people suffering without anywhere to turn for help. That's where Adrenal Fatigue: The 21st Century Stress Syndrome comes in.In Adrenal Fatigue: The 21st Century Stress Syndrome, Dr. Wilson explains not only how stress affects your health but what you can do to un-fatigue your adrenals, protect your health and become more stress hardy. He has written this book in an entertaining, easy-to-follow style that is designed to guide you through everything you need to know about stress, adrenal fatigue and your health. It contains the questionnaire Dr. Wilson developed and used in his practice plus simple self-tests to help you determine if you are experiencing adrenal fatigue and how much it may be affecting you. Dozens of cartoons, illustrations, charts and fascinating case histories from Dr. Wilson's files make this book hard to put down. From beginning to end it will take you step-by-step to reclaim your life from the negative effects of stress.

    But Plato’s role in shaping philosophy was pivotal. On her way to considering the place of philosophy in our ongoing intellectual life, Goldstein tells a new story of its origin, re-envisioning the extraordinary culture that produced the man who produced philosophy. But it is primarily the fate of philosophy that concerns her. Is the discipline no more than a way of biding our time until the scientists arrive on the scene? Have they already arrived? Does philosophy itself ever make progress? And if it does, why is so ancient a figure as Plato of any continuing relevance? Plato at the Googleplex is Goldstein’s startling investigation of these conundra. She interweaves her narrative with Plato’s own choice for bringing ideas to life—the dialogue. Imagine that Plato came to life in the twenty-first century and embarked on a multicity speaking tour. How would he handle the host of a cable news program who denies there can be morality without religion?  How would he mediate a debate between a Freudian psychoanalyst and a tiger mom on how to raise the perfect child? How would he answer a neuroscientist who, about to scan Plato’s brain, argues that science has definitively answered the questions of free will and moral agency? What would Plato make of Google, and of the idea that knowledge can be crowd-sourced rather than reasoned out by experts? With a philosopher’s depth and a novelist’s imagination and wit, Goldstein probes the deepest issues confronting us by allowing us to eavesdrop on Plato as he takes on the modern world.(With black-and-white photographs throughout.)