That all changed in less than a generation with the discovery and development of a new category of medicine known as antibiotics. By 1955, the age-old evolutionary relationship between humans and microbes had been transformed, trivializing once-deadly infections. William Rosen captures this revolution with all its false starts, lucky surprises, and eccentric characters. He explains why, given the complex nature of bacteria—and their ability to rapidly evolve into new forms—the only way to locate and test potential antibiotic strains is by large-scale, systematic, trial-and-error experimentation. Organizing that research needs large, well-funded organizations and businesses, and so our entire scientific-industrial complex, built around the pharmaceutical company, was born. Timely, engrossing, and eye-opening, Miracle Cure is a must-read science narrative—a drama of enormous range, combining science, technology, politics, and economics to illuminate the reasons behind one of the most dramatic changes in humanity’s relationship with nature since the invention of agriculture ten thousand years ago.

    Beautifully presented, it introduces the formation and function of blood cells and diseases that arise from dysfunction and disruption of these processes. Basic science, diagnostic tests and clinical features and management are all easily explained. The 5th edition has been reorganized to increase the focus on discrete disorders to show the increased understanding of the causation of blood disorders and improved diagnostic techniques and clinical management. A new standardized approach to describing disease and management has also been introduced. The authors' engaging style and inviting presentation continue to make Essential Haematology the perfect learning and reference text.Fully supported with downloadable figures from the book, along with a PDF of the captions, at www.wiley.com/go/essentialhaematology

    Transue began chronicling her experiences in her memoir of residency, On Call, and she continues her education here but the source of her knowledge about love, loss, hope and healing are not medical texts or professors but the patients she treats and gets to know – those she helps to wellness and those she must let go.

    It is more concise and easier to read than some, yet it covers the breadth of emergency medicine practice more comprehensively than others. The bottom line is that I like this book. Just as previous editions did, the seventh presents all of the most pertinent and up-to-date information in a well-organized format that is comprehensive yet easy to read. That and many of the attractive new features in this current edition will ensure its place on my bookshelf for years to come."--JAMAWith 418 contributors representing over 120 medical centers around the world, Tintinalli’s Emergency Medicine is the most practical and clinically rigorous reference of its kind. It covers everything from prehospital care, disaster preparedness, and basic resuscitative techniques, to all the major diseases requiring emergency treatment, such as pulmonary emergencies, renal and GU disorders, and hemophilia. This authoritative, in-depth coverage makes this classic text indispensible not only in emergency departments, but also for residents and practitioners when studying or preparing for any exam they may face.While continuing to provide the most current information for acute conditions, the Seventh Edition of Tintinalli’s Emergency Medicine has been substantially revised and updated to cover all of the conditions for which patients seek emergency department care in a concise and easy-to-read-manner.NEW Features• Full-color design with more figures and tables than ever• Reader-friendly chapter presentation makes it easy to find important material.• Updated tables covering drugs and important clinical information• Patient safety considerations and injury prevention are integrated into chapters, as appropriate• Total revision of the dermatology section enables diagnosis by lesion description and body area affected, and provides current treatment• Organ systems sections reorganized to reflect considerations for actual clinical practice.• New chapters: New adult chapters include Natural Disasters, Aneurysms of the Aorta and Major Arteries; Hip and Knee Pain, Aortic Dissection; Acute Urinary Retention; Subarachnoid Hemorrhage and Intracranial Bleeding; Clotting Disorders; Community –acquired Pneumonia and Noninfectious Pulmonary Infiltrates; Type I Diabetes; Type II Diabetes; Anemia; Tests of Hemostasis; Clotting Disorders; Head Injury in Adults and Children; the Transplant Patient; Grief, Death and Dying; and Legal Issues in Emergency Medicine. Twelve new pediatric chapters including The Diabetic Child, Hematologic-Oncologic Emergencies, Ear and Mastoids, Eye Problems in Infants and Children, Neck Masses, GI Bleeding, Nose and Sinuses, Urologic and Gynecologic Procedures in children, Renal emergencies in children, Behavioral and Psychiatric Disorders in children, Pediatric Procedures, Pediatric ECG Interpretation• Greater coverage of procedures throughout for the most common conditions seen in the emergency department.• Companion DVD features an additional 17 chapters, such as Hyperbaric Oxygen Therapy, Principles of Imaging, Prison Medicine, Military Medicine, The Violent Patient, Forensics, Wound Ballistics, and Drug Interactions.• Companion DVD also features videos and animations for teaching and learning performance of important procedures, especially Ultrasound-Guided Procedures

    Now in full color for easier referencing, this New Edition continues the tradition, incorporating a wealth of exciting updates and changes-ensuring you have access to today's authoritative knowledge to best diagnose and treat every pediatric patient you see. Whether you're treating patients in the office or in the hospital, or preparing for the boards, Nelson Textbook of Pediatrics, 18th Edition is your comprehensive guide to providing the best possible care.Get an enhanced focus on general pediatrics with editorial contributions from new editor Dr. Bonita F. Stanton.Treat your inpatient and ambulatory patients more effectively with the absolute latest on new topics such as quality improvement and patient care safety . school violence and bullying . preventive measures . vitamin deficiencies . adolescent rape . effect of war on children . and more.Improve your therapeutic skills with the newest knowledge on the principles of antibiotic therapy . antiviral therapy . antiparasitic therapy . antimycobacterial therapy . and others.Understand the principles of therapy and which drugs and dosages to prescribe for every disease.Locate key content more easily and identify clinical conditions quicker thanks to a new full-color design and full-color photographs.Get an enhanced focus on general pediatrics with editorial contributions from new editor Dr. Bonita F. Stanton.Treat your inpatient and ambulatory patients more effectively with the absolute latest on new topics such as quality improvement and patient care safety *school violence and bullying * preventive measures * vitamin deficiencies * adolescent rape * effect of war on children * and more.Improve your therapeutic skills with the newest knowledge on the principles of antibiotic therapy * antiviral therapy * antiparasitic therapy * antimycobacterial therapy * and others.Understand the principles of therapy and which drugs and dosages to prescribe for every disease.Locate key content more easily and identify clinical conditions quicker thanks to a new full-color design and full-color photographs.

    Part One presents the general principles of pathophysiology and discusses the influence of the environment and the role of genetics in the development of disease. Part Two, organized by body system, examines normal anatomy and physiology, alterations of function in adults, and alterations of function in children.

    But sometimes we don't know what to say or do and don't feel comfortable asking. With sensitive insights and thoughtful anecdotes, Help Me Live provides a personal yet thoroughly researched account of words and actions that are most helpful.

    Residency--and especially the first year, called internship--is legendary for its brutality. Working eighty hours or more per week, most new doctors spend their first year asking themselves why they wanted to be doctors in the first place.Jauhar's internship was even more harrowing than most: he switched from physics to medicine in order to follow a more humane calling--only to find that medicine put patients' concerns last. He struggled to find a place among squadrons of cocky residents and doctors. He challenged the practices of the internship in The New York Times, attracting the suspicions of the medical bureaucracy. Then, suddenly stricken, he became a patient himself--and came to see that today's high-tech, high-pressure medicine can be a humane science after all.Now a thriving cardiologist, Jauhar has all the qualities you'd want in your own doctor: expertise, insight, a feel for the human factor, a sense of humor, and a keen awareness of the worries that we all have in common. His beautifully written memoir explains the inner workings of modern medicine with rare candor and insight. "In Jauhar's wise memoir of his two-year ordeal of doubt and sleep deprivation at a New York hospital, he takes readers to the heart of every young physician's hardest test: to become a doctor yet remain a human being." ― Time

    But as renowned Yale surgeon and medical historian Sherwin B. Nuland shows in this brilliant collection of linked life portraits, the theory bears little resemblance to the truth. Through the centuries, the men and women who have shaped the world of medicine have been not only very human, but also very much the products of their own times and places. Presenting compelling studies of great medical innovators and pioneers, Doctors gives us a fascinating history of modern medicine. Ranging from the legendary Father of Medicine, Hippocrates, to Andreas Vesalius, whose Renaissance masterwork on anatomy offered invaluable new insight into the human body, to Helen Taussig, founder of pediatric cardiology and co-inventor of the original blue baby operation, here is a volume filled with the spirit of ideas and the thrill of discovery.

    We like to imagine that it’s based on evidence and the results of fair tests. In reality, those tests are often profoundly flawed. We like to imagine that doctors are familiar with the research literature surrounding a drug, when in reality much of the research is hidden from them by drug companies. We like to imagine that doctors are impartially educated, when in reality much of their education is funded by industry. We like to imagine that regulators let only effective drugs onto the market, when in reality they approve hopeless drugs, with data on side effects casually withheld from doctors and patients.All these problems have been protected from public scrutiny because they’re too complex to capture in a sound bite. But Dr. Ben Goldacre shows that the true scale of this murderous disaster fully reveals itself only when the details are untangled. He believes we should all be able to understand precisely how data manipulation works and how research misconduct on a global scale affects us. In his own words, “the tricks and distortions documented in these pages are beautiful, intricate, and fascinating in their details.” With Goldacre’s characteristic flair and a forensic attention to detail, Bad Pharma reveals a shockingly broken system and calls for something to be done. This is the pharmaceutical industry as it has never been seen before.

    With the authority of a scholar and the sparkle of an old-time storyteller, Dr. Volney Steele takes the reader from rotgut whiskey to modern anesthetics, from castor oil to antibiotics, and from barroom surgery to modern hospital operations. Dr. Steele wrote Bleed, Blister, and Purge "to shed light on and celebrate the dedication and humanitarianism of those many physicians, nurses, shamans, and people of sound practical sense who saw their patients--often friends and family--through the adversities that bedeviled them."

    Complications lays bare a science not in its idealized form but as it actually is--uncertain, perplexing, and profoundly human.Complications is a 2002 National Book Award Finalist for Nonfiction.

    of Maryland School of Medicine), offers case histories of the health problems of a dozen long-dead famous figures diagnosed from modern medical perspectives. Illustrations depict patients including the odd-looking Pharaoh Akhenaten, C

    This trusted classic delivers comprehensive coverage of the field's must-know basic science and clinical topics in a clear, easy-to-understand presentation. Indispensable for coursework, exam review, and as a clinical refresher, this trusted text has been extensively updated to reflect the latest research and developments.Here's why Clinical Anesthesiology is the best anesthesiology resource:NEW full-color presentationNEW chapters on the most pertinent topics in anesthesiology, including anesthesia outside of the operating room and a revamped peripheral nerve blocks chapter that details ultrasound-guided regional anesthesiaUp-to-date discussion of all relevant areas within anesthesiology, including equipment, pharmacology, regional anesthesia, pathophysiology, pain management, and critical careCase discussions promote application of the concepts to real-world practiceNumerous tables and figures encapsulate important information and facilitate memorization

    Michael Mosley'This book is marvellous: buy it, share it, recommend it.... We are fortunate to have dedicated, caring and humble folks such as Doc Morgan on the Critical Care front line. We are even better off when a writer can capture all that this exciting, mad, glorious and even exasperating job means. If you work in healthcare, know somebody that does, or simply inhabit a body then this book is for you: in fact it's critical.' Peter Brindley, Professor of Critical Care Medicine, Anesthesiology, Medical Ethics University of Alberta'Just wonderful. I love the exploration of what it means to survive, at what cost and so on. Such an important factor and it's a real problem with what we do. An old surgeon once told me ‘just because we can, doesn’t mean we should. Operating is the easiest thing in the world, not doing so is incredibly challenging’. A lovely book.' Dr Nikki Stamp FRACS Cardiothoracic and Transplant Surgeon and author of Can You Die of a Broken Heart?‘An illuminating, compassionate insight into the fascinating world of intensive care.’ Leah Hazzard, author of Hard PushedCritical is an intelligent, compelling and profoundly insightful journey into the world of intensive care medicine and the lives of people who have forever been changed by it. Being critically ill means one or more of your vital organs have failed – this could be your lungs, your heart, your kidneys, gut or even your brain. Starting with the first recognised case in which a little girl was saved by intensive care in 1952 in Copenhagen, Matt writes brilliantly about the fascinating history, practices and technology in this newest of all the major medical specialties. Matt guides us around the ICU by guiding us around the body and the different organs, and in this way, we learn not only the stories of many of the patients he’s treated over the years, but also about the various functions different parts of the body.   He draws on his time spent with real patients, on the brink of death, and explains how he and his colleagues fight against the odds to help them live. Happily many of his cases have happy endings, but Matt also writes movingly about those cases which will always remain with him – the cases where the mysteries of the body proved too hard to solve, or diagnoses came too late or made no difference to the outcome.