That her mother died of the disease, that her own chance of inheriting it was fifty-fifty, that her sister and father directed much of the extraordinary biomedical research to find the gene and a cure, make Wexler's story both astonishingly intimate and scientifically compelling.Alice Wexler's graceful and eloquent account goes beyond the specifics of Huntington's disease to explore the dynamics of family secrets, of living at risk, and the drama and limits of biomedical research. Mapping Fate will be a touchstone for anyone with questions about genetic illness and the possibilities and perils of genetic testing.

    A scathingly funny reinterpretation of the Ten Commandments from the larger, louder half of world-famous magic duo Penn and Teller reveals an atheist's experience in the world: from performing on the Vegas strip with Siegfried and Roy to children and fatherhood to his ongoing dialogue with proselytizers of the Christian Right and the joys of sex while scuba-diving, Penn has an outrageous sense of humor and a brilliantly entertaining opinion on, well, anything you care to think of.

    Through the eyes of her naive and inexperienced younger self, Byron shares remarkable stories inspired by the people she had the privilege to treat. Gripping, poignant, and full of daring black humor, this book reveals the frightening and challenging induction all mental health staff face and highlights their incredible commitment to their patients. It shares the tales of ordinary people with an amazing resilience to life's challenges.

    Over the course of the next five seasons Patsy will see Heather through the loss of both babies and their father. She will also care for her longtime patient Nila, pregnant for the eighth time and trying to make a new life without her abusive husband. And Patsy will try to find some comfort to offer Holly, whose teenage daughter struggles with bulimia. She will help Rebba learn to find pleasure in her body and help Kaz transition into a new body. She will do noisy battle with the IRS in the very few moments she has to spare, and wage her own private battle with uterine cancer.Patricia Harman, a nurse-midwife, manages a women's health clinic with her husband, Tom, an ob-gyn, in West Virginia--a practice where patients open their hearts, where they find care and sometimes refuge. Patsy's memoir juxtaposes the tales of these women with her own story of keeping a small medical practice solvent and coping with personal challenges. Her patients range from Appalachian mothers who haven't had the opportunity to attend secondary school to Ph.D.'s on cell phones. They come to Patsy's small, windowless exam room and sit covered only by blue cotton gowns, and their infinitely varied stories are in equal parts heartbreaking and uplifting. The nurse-midwife tells of their lives over the course of a year and a quarter, a time when her outwardly successful practice is in deep financial trouble, when she is coping with malpractice threats, confronting her own serious medical problems, and fearing that her thirty-year marriage may be on the verge of collapse. In the words of Jacqueline Mitchard, this memoir, "utterly true and lyrical as any novel . . . should be a little classic."

    Dark, humorous, honest, and compassionate, this memoir illustrates the incredible work nurses do and the many challenges they face. A tribute to the wonderfully brave people Chambers met during her career, this book portrays both joyous and difficult experiences.

    But by itself, DNA is just an inert blueprint for life. It is the ribosome--an enormous molecular machine made up of a million atoms--that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases. But this is also a human story of Ramakrishnan's unlikely journey, from his first fumbling experiments in a biology lab to being the dark horse in a fierce competition with some of the world's best scientists. In the end, Gene Machine is a frank insider's account of the pursuit of high-stakes science.

    Organized around the central themes of altruism, knowledge, skill, and duty, the book includes contributions from well-known authors, doctors, nurses, practitioners, and patients. Provocative and moving pieces address what it means to care for a life in a century of unprecedented scientific advances, examining issues of hope and healing from both ends of the stethoscope.

    Overnight, these women were transformed from military spouses into American royalty. They had tea with Jackie Kennedy, appeared on the cover of Life magazine, and quickly grew into fashion icons.Annie Glenn, with her picture-perfect marriage, was the envy of the other wives; JFK made it clear that platinum-blonde Rene Carpenter was his favorite; and licensed pilot Trudy Cooper arrived with a secret that needed to stay hidden from NASA. Together with the other wives they formed the Astronaut Wives Club, providing one another with support and friendship, coffee and cocktails.As their celebrity rose-and as divorce and tragedy began to touch their lives-the wives continued to rally together, forming bonds that would withstand the test of time, and they have stayed friends for over half a century. THE ASTRONAUT WIVES CLUB tells the story of the women who stood beside some of the biggest heroes in American history.

    . . but rarely acknowledging.Filled with insights and observations that instantly ring true—and could have come only from Nora Ephron—I Remember Nothing is pure joy.

    Despite her flapping arms and shaking legs, she continued to speak clearly and was able to finish her speech. It was as if she had suddenly become two people: a calm orator and a shuddering wreck. Then the seizures happened again and again. The Shaking Woman tracks Hustvedt’s search for a diagnosis, one that takes her inside the thought processes of several scientific disciplines, each one of which offers a distinct perspective on her paroxysms but no ready solution. In the process, she finds herself entangled in fundamental questions: What is the relationship between brain and mind? How do we remember? What is the self?During her investigations, Hustvedt joins a discussion group in which neurologists, psychiatrists, psychoanalysts, and brain scientists trade ideas to develop a new field: neuropsychoanalysis. She volunteers as a writing teacher for psychiatric in-patients at the Payne Whitney clinic in New York City and unearths precedents in medical history that illuminate the origins of and shifts in our theories about the mind-body problem. In The Shaking Woman, Hustvedt synthesizes her experience and research into a compelling mystery: Who is the shaking woman? In the end, the story she tells becomes, in the words of George Makari, author of Revolution in Mind, “a brilliant illumination for us all.”

    Writer, M.D. celebrates this rich tradition with a collection of fiction and nonfiction by today’s most beloved physician-writers, including,• Abraham Verghese, on the lost art of the physical exam• Pauline Chen, on the bond between a med student and her first cadaver• Atul Gawande, on the ethical dilemmas of a young surgical intern• Danielle Ofri, on the devastation of losing a patient• Ethan Canin, on love, poetry, and growing oldThese essays and stories illuminate the inner lives of men and women who deal with trauma, illness, mortality, and grief on a daily basis. Read together, they provide a candid, moving, one-of-a-kind glimpse behind the doctor’s mask.

    He chronicles the torture of finding a job before the internet when you had to talk on the phone all the time, and fantasizes, as we all do, about who to tell off when he finally wins an Oscar. As Gary himself says, "These are essays from my childhood and young adulthood about things that still annoy me."Original, brazen, and laugh out loud funny, Do You Mind if I Cancel? is something not to be missed.

    Months later, several health professionals faced criminal allegations that they deliberately injected numerous patients with drugs to hasten their deaths. Five Days at Memorial, the culmination of six years of reporting, unspools the mystery of what happened in those days, bringing the reader into a hospital fighting for its life and into a conversation about the most terrifying form of health care rationing.In a voice at once involving and fair, masterful and intimate, Fink exposes the hidden dilemmas of end-of-life care and reveals just how ill-prepared we are in America for the impact of large-scale disasters—and how we can do better. A remarkable book, engrossing from start to finish, Five Days at Memorial radically transforms your understanding of human nature in crisis.

    Her marriage of more than thirty years was suffering, and she was virtually immobilized by fear and anxiety. As the daughter of parents who both died before she was thirty, Stern was terrified of illness and death, and despite the fact that her acclaimed career as a food and travel writer required her to spend a great deal of time on airplanes, she suffered from a persistent fear of flying and severe claustrophobia. But a strange thing happened one day on a plane that was grounded at the Minneapolis airport for six horrible, foodless, airless hours. A young man on a trip with his classmates suddenly became dizzy and pale because he hadn’t eaten in many hours, and there was no food left on the plane. Without thinking about it, Jane gave him the candy bar that she had in her purse. A short time later the color had returned to his cheeks, the boy was laughing again with his friends, and Jane realized that this one small act of kindness—helping another person who was suffering—had provided her with comfort and a sense of well-being.It was shortly thereafter that this fifty-two-year-old writer decided to become an emergency medical technician, eventually coming to be known as Ambulance Girl. Stern tells her story with great humor and poignancy, creating a wonderful portrait of a middle-aged, Woody Allen–ish woman who was “deeply and neurotically terrified of sick and dead people,” but who went out into the world to save other people’s lives as a way of saving her own. Her story begins with the boot camp of EMT training: 140 hours at the hands of a dour ex-marine who took delight in presenting a veritable parade of amputations, hideous deformities, and gross disasters. Jane—overweight and badly out of shape—had to surmount physical challenges like carrying a 250-pound man seated in a chair down a dark flight of stairs. After class she did rounds in the emergency room of a local hospital, where she attended to a schizophrenic kickboxer who had tried to kill his mother that morning and a stockbroker who was taken off the commuter train to Manhattan with delirium tremens so bad it killed him.Each call Stern describes is a vignette of human nature, often with a life in the balance. From an AIDS hospice to town drunks, yuppie wife beaters to psychopaths, Jane comes to see the true nature and underlying mysteries of a town she had called home for twenty years. Throughout the book we follow her as she gets her sea legs and finally bonds with the burly, handsome firefighters who become her colleagues. At the end, she is named the first woman officer of the department—a triumph we joyously share with her.Ambulance Girl is an inspiring story by a woman who found, somewhat late in life, that “in helping others I learned to help myself.” It is a book to be treasured and shared.

    But when she least expects it, her reckless past catches up with her; convicted and sentenced to fifteen months at an infamous women's prison in Connecticut, Piper becomes inmate #11187-424. From her first strip search to her final release, she learns to navigate this strange world with its arbitrary rules and codes, its unpredictable, even dangerous relationships. She meets women from all walks of life, who surprise her with tokens of generosity, hard truths and simple acts of acceptance.