But AIDS is just one of the many emerging viruses for which we have, as yet, no cure. Even the old plagues – TB, cholera, bubonic plague – are making a comeback, resistant now to our drugs.Frank Ryan, a leading authority on disease, describes the groundbreaking research of the world’s leading experts in the field to show both where these viruses come from and why they prove to be so lethal, and advances a radical new biological theory for the origins and behaviour of plague viruses. Full of vivid despatches from the front line of research and medicine, 'Virus X' is terrifying and essential reading for anyone interested in the effects of plague viruses on human evolution.“Extremely well written…Frank Ryan has the page-turning and spine-chilling ability of a good novelist”MATT RIDLEY, 'Sunday Telegraph'“Compelling and frightening…the plot could not be bettered”MICHAEL SMITH, 'Scotsman'“Ryan is very good at making technical matters comprehensible to the lay reader but more impressive still is the way he conveys the intellectual excitement and elation of scientific discovery”ANTHONY DANIELS, 'Literary Review'“Ryan takes us through the drama of discovery and challenges the notion that certain questions are too appalling to contemplate”DAVID BRADLEY, 'New Scientist'“Dr Ryan writes well in a difficult technical field, weaving the technicalities of scientific history, medicine, molecular biology and evolution into the human narratives…very readable and disturbing”JOHN R.G. TURNER, 'New York Times'

    Although molecular topics are presented first, instructors can assign the chapters in any sequence. Pedagogical features such as chapter-opening “Key Questions” and strategically placed “Keynotes” help readers to efficiently master genetic concepts. The Genetics Place Companion Website contains interactive iActivities and narrated animations that help readers visualize and understand processes and concepts that are illustrated in the book. Genetics: An Introduction, DNA: The Genetic Material, DNA Replication, Gene Control of Proteins, Gene Expression: Transcription,Gene Expression: Translation, DNA Mutation, DNA Repair, and Transposable Elements, Structural Genomics, Functional and Comparative Genomics, Recombinant DNA Technology, Mendelian Genetics, Chromosomal Basis of Inheritance, Extensions of and Deviations from Mendelian Genetic Principles, Genetic Mapping in Eukaryotes, Genetics of Bacteria and Bacteriophages, Variations in Chromosome Structure and Number, Regulation of Gene Expression in Bacteria and Bacteriophages, Regulation of Gene Expression in Eukaryotes, Genetic Analysis of Development, Genetics of Cancer, Quantitative Genetics, Population Genetics, Molecular Evolution Intended for those interested in learning the basics of genetics

    Our instincts—for food, sex, or territorial protection— evolved for life on the savannahs 10,000 years ago, not in today’s world of densely populated cities, technological innovations, and pollution. We now have access to a glut of larger-than-life objects, from candy to pornography to atomic weapons—that gratify these gut instincts with often-dangerous results. Animal biologists coined the term “supernormal stimuli” to describe imitations that appeal to primitive instincts and exert a stronger pull than real things, such as soccer balls that geese prefer over eggs. Evolutionary psychologist Deirdre Barrett applies this concept to the alarming disconnect between human instinct and our created environment, demonstrating how supernormal stimuli are a major cause of today’s most pressing problems, including obesity and war. However, Barrett does more than show how unfettered instincts fuel dangerous excesses. She also reminds us that by exercising self-control we can rein them in, potentially saving ourselves and civilization. 55 illustrations.

    But how the mind works remains one of humankind's greatest mysteries. With boundless curiosity and enthusiasm, Shannon Moffett, a Stanford medical student, takes us down the halls of neuroscience to the front lines of cutting-edge research and medicine to meet some of today's most extraordinary scientists and thinkers, all grappling with provocative questions: Why do we dream? How does memory work? How do we see? What happens when we think? Each chapter delves into a different aspect of the brain, following the experts as they chart new ground. Moffett takes us to a lab where fMRI scans reveal the multitude of stimuli that our brains unconsciously take in; inside an operating room where a neurosurgeon removes a bullet from a patient's skull; to the lab of Christof Koch, a neuroscientist tracking individual neurons in order to crack the code of consciousness; and to a research lab where scientists are investigating the relationship between dreams and waking life. She also takes us beyond the scientific world—to a Zen monk's zendo, where she explores the effects of meditation on the brain; inside the home of a woman suffering from dissociative identity disorder; to a conference with the philosopher Daniel Dennett, who uses illusions, magic, tricks, and logic to challenge our assumptions about the mind; and to the home of the late Nobel Laureate Francis Crick, co-discoverer with James Watson of DNA's double-helix structure. Filled with fascinating case studies and featuring a timeline that tracks the development of the brain from conception to death, The Three Pound Enigma is a remarkable exploration of what it means to be human.

    Examines the changes taking place in modern America, and discusses shoddy workmanship, poor service, inflation, crime, and religious cults.

    this is one of those rare books that will change your beliefs - and in doing so will change your life. tHE ANt AND tHE FERRARI offers readers a clear, navigable path through the big questions that confront us all today. What is the meaning of life? Can we be ethical beings in today's world? Can we know if there is life after death? Is there such a thing as Absolute truth? What caused the Big Bang and why should you care?

    That word is formication, and the implied sense of horror and fascination, contends Richard Conniff, is something many of us actually crave. His Spineless Wonders presents an unabashed wallow in the joy of formication. Spineless Wonders is an engaging, sophisticated, and humorous mix of natural history and human lore. Through his journalistic assignments, Richard Conniff has been in contact with invertebrates for more than twenty years - tarantulas in the upper Amazon region, dragonflies in Arizona, squid in Florida, and flies on the rim of his beer glass. Discoveries about the extraordinary habits and idiosyncrasies of the moth, the leech, the ant, and the slime eel are opening new frontiers in the exploration of our natural universe. Spineless Wonders takes us directly to these wild and wonderful outposts to observe the hazards of being around invertebrates, the bizarre adaptions that enable them to survive in the world, and also the astonishing work they do - work that enables us to survive.

    Prusiner received a Nobel Prize, the world's most prestigious award for achievement in physiology or medicine. That he was the sole recipient of the award for the year was entirely appropriate, for his struggle to identify the agent responsible for ravaging the brains of animals suffering from scrapie and mad cow disease, and of humans with Creutzfeldt-Jakob disease, had been waged largely alone and in some cases in the face of strenuous disagreement.   In this book, Prusiner tells the remarkable story of his discovery of prions—infectious proteins that replicate and cause disease but surprisingly contain no genetic material—and reveals how superb and meticulous science is actually practiced using talented teams of researchers who persevere. He recounts the frustrations and rewards of years of research and offers fascinating portraits of his peers as they raced to discover the causes of fatal brain diseases. Prusiner’s hypothesis, once considered heresy, now stands as accepted science and the basis for developing diagnoses and eventual cures. He closes with a meditation on the legacy of his discovery: What will it take to cure Alzheimer’s, Parkinson’s, Lou Gehrig’s and other devastating diseases of the brain?

    The sixteenth and seventeenth centuries witnessed the Copernican Revolution, which bodychecked the Earth as the pivot point of creation and joined us with the rest of the cosmos as one planet among many orbiting the Sun. Three centuries later came the second great scientific revolution: the Darwinian Revolution. It removed us from a distinct, divine biological status to place us wholly in the ebb and flow of all terrestrial life. This book describes how we’re in the midst of a third great scientific revolution, five centuries in the making: the Stardust Revolution. It is the merging of the once-disparate realms of astronomy and evolutionary biology, and of the Copernican and Darwinian Revolutions, placing life in a cosmic context. This book takes readers on a grand journey that begins on the summit of California’s Mount Wilson, where astronomers first realized that the universe is both expanding and evolving, to a radio telescope used to identify how organic molecules—the building blocks of life—are made by stars. It’s an epic story told through a scientific cast that includes some of the twentieth century’s greatest minds—including Nobel laureate Charles Townes, who discovered cosmic water—as well as the most ambitious scientific explorers of the twenty-first century, those racing to find another living planet. Today, an entirely new breed of scientists—astrobiologists and astrochemists—are taking the study of life into the space age. Astrobiologists study the origins, evolution, and distribution of life, not just on Earth, but in the universe. Stardust science is filling in the missing links in our evolutionary story, ones that extend our family tree back to the stars.

    Douglas Futuyma presents an overview of current thinking on theories of evolution, aimed at an undergraduate audience.

    Just a half century ago, this idea was revolutionary. In April 1953, James Watson and Francis Crick published in Nature their groundbreaking work revealing the double helix structure of DNA. While this discovery received wide attention from both mainstream media and the academic community, it was just one part of the bigger story in this history of molecular biology. By the mid-1950s, the scientific community confirmed that genes were indeed comprised of DNA; they just needed to crack the genetic code—and the race was on. Life’s Greatest Secret is the full and rich history of this challenge and the characters—many of whom were not biologists—whose work contributed to this grand scientific endeavor: mathematician and father of cybernetics Norbert Wiener, physicist Erwin Schrödinger, information theorist Claude Shannon, and biologists Jacques Monod and Marshall Nirenberg.In Life’s Greatest Secret, science historian and zoologist Matthew Cobb shows that the race to crack the genetic code was mostly a matter of craft—individuals or small groups struggling with ideas and concepts as much as they were with facts, trying to find the right experiment to answer the right questions, even if they didn’t know what the questions were, and finding that, even when the most definitive answer served mostly to reveal more ignorance, whether in 1953, with Watson and Crick, or in 1961, when Nirenberg and Matthaei showed how DNA codes for specific amino acids, and again and again thereafter, or in 2000, with the first publication of a human genome. Each discovery was a leap forward in our understanding of the natural world and our place within in, akin to the discoveries of Galileo and Einstein in the realm of physics, or the publication of Darwin’s On the Origin of Species. And each served to show how much bigger the problem was that anyone had previously imagined, a trend that continues, as Cobb shows, even today, whether we are discussing gene regulation, epigenetics, or GMOs.Life’s Greatest Secret is a story of ideas and of experimentation, of ingenuity, insight, and dead-ends, in the hunt to make the greatest discovery of twentieth century biology. Ultimately, though, this is a story of humans exploring what it is that makes us human.

    Like most people, you probably wake up, get hungry for meals and doze off in bed around the same time every day. If you’ve ever experienced jet lag or pulled an all-nighter, you know that this schedule can easily be thrown off kilter. But for some people, that imbalance—difficulty sleeping at night, hunger at odd times, or sudden fatigue at noon—is a constant. If you're one of those people, Dr. Satchin Panda, one of the leading researchers on circadian rhythms, has a plan to reset your body clock.Beginning with an in-depth explanation of the circadian clock—why it’s important, how it works, and how to know it isn’t working—The Circadian Code outlines lifestyle changes to make to get back on track. It's a concrete plan to enhance weight loss, improve sleep, optimize exercise, and manage technology so that it doesn’t interfere with your body’s natural rhythm. Dr. Panda’s life-changing methods show you how to prevent and reverse ailments like diabetes, cancer, and dementia, as well as microbiome conditions like acid reflux, heartburn, and irritable bowel disease.

    In contrast, the 2011 revision suggested that 9.1 billion would be achieved much earlier, maybe by 2050 or before, and by 2100 there would be 10.1 billion of us. What's more, they implied that global human population might still be slightly rising in our total numbers a century from now. So what shall we do? Are there too many people on the planet? Is this the end of life as we know it?Distinguished geographer Professor Danny Dorling thinks we should not worry so much and that, whatever impending doom may be around the corner, we will deal with it when it comes. In a series of fascinating chapters he charts the rise of the human race from its origins to its end-point of population 10 billion. Thus he shows that while it took until about 1988 to reach 5 billion we reached 6 billion by 2000, 7 billion eleven years later and will reach 8 billion by 2025.By recording how we got here, Dorling is able to show us the key issues that we face in the coming decades: how we will deal with scarcity of resources; how our cities will grow and become more female; why the change that we should really prepare for is the population decline that will occur after 10 billion.Population 10 Billion is a major work by one of the world's leading geographers and will change the way you think about the future. Packed full of counter-intuitive ideas and observations, this book is a tool kit to prepare for the future and to help us ask the right questions

    This distinctive text was developed to stand apart from all other A&P texts with unparalleled art, a writing style that has been acclaimed by both users and reviewers and clinical coverage that offers the perfect balance without being too much. Saladin's well-accepted organization of topics is based upon the most logical physiological ties between body systems. This text requires no prior knowledge of college chemistry or cell biology, and is designed for a two-semester A&P college course.

    People in this middle place have sustained traumatic brain injuries or are the victims of stroke or degenerative diseases, such as Alzheimer’s and Parkinson’s. Many are oblivious to the outside world, and their doctors believe they are incapable of thought. But a sizeable number are experiencing something different: intact minds adrift deep within damaged brains and bodies. Following Owen’s journey of exciting medical discovery, Into the Gray Zone asks some tough and terrifying questions, such as: What is life like for these patients? What can their families and friends do to help them? What are the ethical implications for religious organizations, politicians, the Right to Die movement, and even insurers? And perhaps most intriguing of all: in defining what a life worth living is, are we too concerned with the physical and not giving enough emphasis to the power of thought? What, truly, defines a satisfying life?