We see it, touch it, and live in it every day. It is a habitat for a mesmerizingly complex world of micro-organisms and physical functions that are vital to our health and our survival. It is also a waste removal plant, a warning system for underlying disease and a dynamic immune barrier to infection. One of the first things people see about us, skin is crucial to our sense of identity, providing us with social significance and psychological meaning. And yet our skin and the fascinating way it functions is largely unknown to us. In prose as lucid as his research underlying it is rigorous, blending in memorable stories from the past and from his own medical experience, Monty Lyman has written a revelatory book exploring our outer surface that will surprise and enlighten in equal measure. Through the lenses of science, sociology, and history--on topics as diverse as the mechanics and magic of touch (how much goes on in the simple act of taking keys out of a pocket and unlocking a door is astounding), the close connection between the skin and the gut, what happens instantly when one gets a paper cut, and how a midnight snack can lead to sunburn--Lyman leads us on a journey across our most underrated and unexplored organ and reveals how our skin is far stranger, more wondrous, and more complex than we have ever imagined.

    Leslie Jamison deftly excavates the stories we tell about addiction--both her own and others'--and examines what we want these stories to do, and what happens when they fail us.All the while, she offers a fascinating look at the larger history of the recovery movement, and at the literary and artistic geniuses whose lives and works were shaped by alcoholism and substance dependence, including John Berryman, Jean Rhys, Raymond Carver, Billie Holiday, David Foster Wallace, and Denis Johnson, as well as brilliant figures lost to obscurity but newly illuminated here.For the power of her striking language and the sharpness of her piercing observations, Jamison has been compared to such iconic writers as Joan Didion and Susan Sontag. Yet her utterly singular voice also offers something new. With enormous empathy and wisdom, Jamison has given us nothing less than the story of addiction and recovery in America writ large, a definitive and revelatory account that will resonate for years to come.

    A school cafeteria lunch is infected with a drug-resistant strain of E. coli.... Thousands in a bustling shopping mall inhale a lethal mist of smallpox, turning each individual into a highly infectious agent of suffering and death....Dr. Michael Osterholm knows all too well the horrifying scenarios he describes. In this eye-opening account, the nation’s leading expert on bioterrorism sounds a wake-up call to the terrifying threat of biological attack — and America’s startling lack of preparedness. He demonstrates the havoc these silent killers can wreak, exposes the startling ease with which they can be deployed, and asks probing questions about America’s ability to respond to such attacks. Are most doctors and emergency rooms able to diagnose correctly and treat anthrax, smallpox, and other potential tools in the bioterrorist’s arsenal? Is the government developing the appropriate vaccines and treatments? The answers are here in riveting detail — what America has and hasn’t done to prevent the coming bioterrorist catastrophe. Impeccably researched, grippingly told, Living Terrors presents the unsettling truth about the magnitude of the threat. And more important, it presents the ultimate insider’s prescription for change: what we must do as a nation to secure our freedom, our future, our lives.

    We’ll look at what identical twins can teach us about the epigenetic effects of our environment and experiences, why certain genes are 'switched on' or off at various stages of embryonic development, and how scientists have reversed the specialization of cells to clone frogs from a single gut cell. In Introducing Epigenetics, Cath Ennis and Oliver Pugh pull apart the double helix, examining how the epigenetic building blocks and messengers that interpret and edit our genes help to make us, well, us.

    Michael Mosley'This book is marvellous: buy it, share it, recommend it.... We are fortunate to have dedicated, caring and humble folks such as Doc Morgan on the Critical Care front line. We are even better off when a writer can capture all that this exciting, mad, glorious and even exasperating job means. If you work in healthcare, know somebody that does, or simply inhabit a body then this book is for you: in fact it's critical.' Peter Brindley, Professor of Critical Care Medicine, Anesthesiology, Medical Ethics University of Alberta'Just wonderful. I love the exploration of what it means to survive, at what cost and so on. Such an important factor and it's a real problem with what we do. An old surgeon once told me ‘just because we can, doesn’t mean we should. Operating is the easiest thing in the world, not doing so is incredibly challenging’. A lovely book.' Dr Nikki Stamp FRACS Cardiothoracic and Transplant Surgeon and author of Can You Die of a Broken Heart?‘An illuminating, compassionate insight into the fascinating world of intensive care.’ Leah Hazzard, author of Hard PushedCritical is an intelligent, compelling and profoundly insightful journey into the world of intensive care medicine and the lives of people who have forever been changed by it. Being critically ill means one or more of your vital organs have failed – this could be your lungs, your heart, your kidneys, gut or even your brain. Starting with the first recognised case in which a little girl was saved by intensive care in 1952 in Copenhagen, Matt writes brilliantly about the fascinating history, practices and technology in this newest of all the major medical specialties. Matt guides us around the ICU by guiding us around the body and the different organs, and in this way, we learn not only the stories of many of the patients he’s treated over the years, but also about the various functions different parts of the body.   He draws on his time spent with real patients, on the brink of death, and explains how he and his colleagues fight against the odds to help them live. Happily many of his cases have happy endings, but Matt also writes movingly about those cases which will always remain with him – the cases where the mysteries of the body proved too hard to solve, or diagnoses came too late or made no difference to the outcome.

    From miraculous pregnancies to dirty protests, and from violent attacks on prisoners to heartbreaking acts of self-harm, she has witnessed it all. In this memoir, Amanda reveals the stories, the patients and the cases that have shaped a career helping those most of us would rather forget.

    Richard Davenport-Hines, an eminent, prize-winning historian, uncovers the centrality of drug abuse in our modern industrial society, from the drug habits of Charles Dickens and John F. Kennedy to today's $400 billion annual worldwide trade in illicit drugs (the same volume as the oil industry). A vivid portrayal of the people and events that have shaped the history of narcotics, The Pursuit of Oblivion reveals that, contrary to the assumption underlying current drug policies, our need to escape reality and our body's need for physical pleasure are both ineradicable aspects of our humanity, unchangeable by government initiative.

    But a physician’s incorrect diagnosis will always be a matter of life and death. Dr. Baticulon’s dispatches from the country’s leading public hospital are told in language that requires no further acrobatics. How do you tell a mother that the smiling ten-year-old boy in her arms will not survive the following week? How do you tell a little girl she’ll never be able to go home to play because her parents can’t afford P54,000 for her surgery? How do you live with yourself after breaking a promise to save an eight-year-old boy’s life? Like the trenches of war zones, the operating room is the frontline of life’s most difficult questions. Here are a neurosurgeon’s gripping ruminations on hope and loss."—Lourd De Veyra"Ronnie Baticulon follows in the footsteps of many other physicians for whom the task of understanding and healing humanity did not stop at the clinic or the operating room. They used words and language not only for their patients but also for themselves—a long and distinguished line from Rabelais, Chekhov, and Maugham to Michael Crichton, Richard Selzer, Oliver Sacks, and of course our own Jose Rizal and Arturo Rotor. Dr. Baticulon is a worthy addition to that tradition."—Jose Y. Dalisay Jr.

    Affiliated with discontinuity, alarm, and silence, it raises fundamental questions about the constitution of self and other, the stability of location, systems of transfer, and the destination of speech. Profoundly changing our concept of long-distance, it is constantly transmitting effects of real and evocative power. To the extent that it always relates us to the absent other, the telephone, and the massive switchboard attending it, plugs into a hermeneutics of mourning. The Telephone Book, itself organized by a "telephonic logic," fields calls from philosophy, history, literature, and psychoanalysis. It installs a switchboard that hooks up diverse types of knowledge while rerouting and jamming the codes of the disciplines in daring ways. Avital Ronell has done nothing less than consider the impact of the telephone on modern thought. Her highly original, multifaceted inquiry into the nature of communication in a technological age will excite everyone who listens in. The book begins by calling close attention to the importance of the telephone in Nazi organization and propaganda, with special regard to the philosophy of Martin Heidegger. In the Third Reich the telephone became a weapon, a means of state surveillance, "an open accomplice to lies." Heidegger, in Being and Time and elsewhere, elaborates on the significance of "the call." In a tour de force response, Ronell mobilizes the history and terminology of the telephone to explicate his difficult philosophy.Ronell also speaks of the appearance of the telephone in the literary works of Duras, Joyce, Kafka, Rilke, and Strindberg. She examines its role in psychoanalysis—Freud said that the unconscious is structured like a telephone, and Jung and R. D. Laing saw it as a powerful new body part. She traces its historical development from Bell's famous first call: "Watson, come here!" Thomas A. Watson, his assistant, who used to communicate with spirits, was eager to get the telephone to talk, and thus to link technology with phantoms and phantasms. In many ways a meditation on the technologically constituted state, The Telephone Book opens a new field, becoming the first political deconstruction of technology, state terrorism, and schizophrenia. And it offers a fresh reading of the American and European addiction to technology in which the telephone emerges as the crucial figure of this age.

     Loss of memory is not a natural part of aging--and this book explains why.Celebrated neurologist David Perlmutter reveals how everyday memory-loss--misplacing car keys, forgetting a name, losing concentration in meetings--is actually a warning sign of a distressed brain. Here he and Carol Colman offer a simple plan for repairing those problems, clarifying misconstrued connections between memory loss and aging, and regaining and maintaining mental clarity by offering the tools for:Building a better brain through nutrition, lifestyle changes, and brain workoutsCoping with specific brain disorders such as stroke, vascular dementia, Alzheimer's, Parkinson's, multiple sclerosis, and Lou Gehrig's diseaseUnderstanding risk factors and individually tailoring a diet and supplementary programFeatures a Life Style Audit, quizzes, a brain fitness program with the most effective ways to exercise your brain, and a nutritional program that details the best brain food and supplements.

    Immerse yourself in the history of medicine - a colourful story of skill, serendipity, trial and error, moments of genius, and dogged determination.From traditional chinese medicine to today's sophisticated gene therapies and robotic surgery, A Short History of Medicine combines riveting storytelling and beautiful images, historical accounts and lucid explanations, to illuminate the story of medicine through time.Witness early, bloody, anaesthetic-free operations; see the first crude surgical instruments; trace the mapping of the circulatory system; follow the painstaking detective work that led to the decoding of the human genome; and understand the role that potions, cures, therapies, herbal medicines, and drugs have played in the human quest to tame and conquer disease, injury, and death.A Short History of Medicine is an engrossing illustrated history and tale of drama and discovery that celebrates the milestones of medical history across generations and cultures.

    Doctors and scientists at prestigious institutions were pressured to produce medical advances to compete with the perceived threats coming from the Soviet Union. In Against Their Will, authors Allen Hornblum, Judith Newman, and Gregory Dober reveal the little-known history of unethical and dangerous medical experimentation on children in the United States. Through rare interviews and the personal correspondence of renowned medical investigators, they document how children—both normal and those termed "feebleminded"—from infants to teenagers, became human research subjects in terrifying experiments. They were drafted as "volunteers" to test vaccines, doused with ringworm, subjected to electric shock, and given lobotomies. They were also fed radioactive isotopes and exposed to chemical warfare agents. This groundbreaking book shows how institutional superintendents influenced by eugenics often turned these children over to scientific researchers without a second thought. Based on years of archival work and numerous interviews with both scientific researchers and former test subjects, this is a fascinating and disturbing look at the dark underbelly of American medical history.

    Explaining, and moving beyond, the five phase (element) system, he shows that this Eastern practice is as much a spiritual science as a physical one. Accessible to the layman, yet a resource for the professional in any healing art, this book examines the natural energy functions of the human organism as a key to mental, emotional and spiritual health. It offers new insight into disease, showing how it is not merely an invasion from the outside, but rather a byproduct of a person's unsuccessful attempt to restore one's own balance.

    It’s a story about literature, community, and technology—about what stories are being told, who’s telling them, how, and why.With provocative discussions from both professional and fan writers, on subjects from Star Trek to The X-Files and Buffy the Vampire Slayer to Harry Potter, Twilight, and beyond, Fic sheds light on the widely misunderstood world(s) of fanfiction—not only how fanfiction is transforming the literary landscape, but how it already has.Fic features a foreword by Lev Grossman (author of The Magicians) and interviews with Jonathan Lethem, Doug Wright, and Eurydice (Vivean Dean).Katie Forsythe/wordstringsCyndy Aleo (algonquinrt; d0tpark3r)V. Arrow (aimmyarrowshigh)Tish Beaty (his_tweet)Brad BellAmber BensonPeter Berg (Homfrog)Kristina BusseRachel CaineFrancesca CoppaRandi Flanagan (BellaFlan)Jolie FontenotWendy C. Fries (Atlin Merrick)Ron HoganBethan JonesChristina Lauren (Christina Hobbs/tby789 and Lauren Billings/LolaShoes)Jacqueline LichtenbergRukmini Pande and Samira NadkarniChris RankinTiffany ReiszAndrew ShafferAndy SawyerHeidi Tandy (Heidi8)Darren WershlerJules Wilkinson (missyjack)Jen Zern (NautiBitz)

    The ideas in De la grammatologie sparked lively debates in intellectual circles that included students of literature, philosophy, and the humanities, inspiring these students to ask questions of their disciplines that had previously been considered improper. Thirty years later, the immense influence of Derrida's work is still igniting controversy, thanks in part to Gayatri Spivak's translation, which captures the richness and complexity of the original. This corrected edition adds a new index of the critics and philosophers cited in the text and makes one of contemporary criticism's most indispensable works even more accessible and usable.