In a lab filled with curiosities--beakers, microscopes, Bunsen burners, and hundreds upon hundreds of books--sat an investigator who would go on to crack at least two thousand cases in his forty-year career. Known as the "American Sherlock Holmes," Edward Oscar Heinrich was one of America's greatest--and first--forensic scientists, with an uncanny knack for finding clues, establishing evidence, and deducing answers with a skill that seemed almost supernatural.Heinrich was one of the nation's first expert witnesses, working in a time when the turmoil of Prohibition led to sensationalized crime reporting and only a small, systematic study of evidence. However with his brilliance, and commanding presence in both the courtroom and at crime scenes, Heinrich spearheaded the invention of a myriad of new forensic tools that police still use today, including blood spatter analysis, ballistics, lie-detector tests, and the use of fingerprints as courtroom evidence. His work, though not without its serious--some would say fatal--flaws, changed the course of American criminal investigation.Based on years of research and thousands of never-before-published primary source materials, American Sherlock captures the life of the man who pioneered the science our legal system now relies upon--as well as the limits of those techniques and the very human experts who wield them.

    The outcome was unexpected—when Henry awoke, he could no longer form new memories, and for the rest of his life would be trapped in the moment. But Henry’s tragedy would prove a gift to humanity. As renowned neuroscientist Suzanne Corkin explains in Permanent Present Tense, she and her colleagues brought to light the sharp contrast between Henry’s crippling memory impairment and his preserved intellect. This new insight that the capacity for remembering is housed in a specific brain area revolutionized the science of memory. The case of Henry—known only by his initials H. M. until his death in 2008—stands as one of the most consequential and widely referenced in the spiraling field of neuroscience. Corkin and her collaborators worked closely with Henry for nearly fifty years, and in Permanent Present Tense she tells the incredible story of the life and legacy of this intelligent, quiet, and remarkably good-humored man. Henry never remembered Corkin from one meeting to the next and had only a dim conception of the importance of the work they were doing together, yet he was consistently happy to see her and always willing to participate in her research. His case afforded untold advances in the study of memory, including the discovery that even profound amnesia spares some kinds of learning, and that different memory processes are localized to separate circuits in the human brain. Henry taught us that learning can occur without conscious awareness, that short-term and long-term memory are distinct capacities, and that the effects of aging-related disease are detectable in an already damaged brain.Undergirded by rich details about the functions of the human brain, Permanent Present Tense pulls back the curtain on the man whose misfortune propelled a half-century of exciting research. With great clarity, sensitivity, and grace, Corkin brings readers to the cutting edge of neuroscience in this deeply felt elegy for her patient and friend.

    Q, an internationally renowned neurosurgeon and neuroscientist who leads cutting-edge research to cure brain cancer. But not too long ago, he was Freddy, a nineteen-year-old undocumented migrant worker toiling in the tomato fields of central California. In this gripping memoir, Alfredo Quiñones-Hinojosa tells his amazing life story—from his impoverished childhood in the tiny village of Palaco, Mexico, to his harrowing border crossing and his transformation from illegal immigrant to American citizen and gifted student at the University of California at Berkeley and at Harvard Medical School. Packed with adventure and adversity—including a few terrifying brushes with death—Becoming Dr. Q is a testament to persistence, hard work, the power of hope and imagination, and the pursuit of excellence. It’s also a story about the importance of family, of mentors, and of giving people a chance.

    This critically acclaimed biography offers an unprecedented look at William Masters and Virginia Johnson, their pioneering studies on intimacy, and their lasting impact on the love lives of today's men and women.

    After World War II, Don's work with the Air Force brought them to Colorado, where their twelve children perfectly spanned the baby boom: the oldest born in 1945, the youngest in 1965. In those years, there was an established script for a family like the Galvins—aspiration, hard work, upward mobility, domestic harmony—and they worked hard to play their parts. But behind the scenes was a different story: psychological breakdown, sudden shocking violence, hidden abuse. By the mid-1970s, six of the ten Galvin boys, one after another, were diagnosed as schizophrenic. How could all this happen to one family?What took place inside the house on Hidden Valley Road was so extraordinary that the Galvins became one of the first families to be studied by the National Institute of Mental Health. Their story offers a shadow history of the science of schizophrenia, from the era of institutionalization, lobotomy, and the schizophrenogenic mother to the search for genetic markers for the disease, always amid profound disagreements about the nature of the illness itself. And unbeknownst to the Galvins, samples of their DNA informed decades of genetic research that continues today, offering paths to treatment, prediction, and even eradication of the disease for future generations.With clarity and compassion, bestselling and award-winning author Robert Kolker uncovers one family's unforgettable legacy of suffering, love, and hope.

    In this hilarious, high-spirited, sometimes harrowing memoir, Shapiro invites us into his battle with cancer, his romance with an oncology nurse, his journey through graduate school, and his most important life lessons. He tells his story with wit and grace and indomitable spirit, showing us that only when the rhythm of life is stirred violently are able to discover its full beauty.

    It is the history of who you are and how you came to be. It is unique to you, as it is to each of the 100 billion modern humans who have ever drawn breath. But it is also our collective story, because in every one of our genomes we each carry the history of our species births, deaths, disease, war, famine, migration, and a lot of sex. Since scientists first read the human genome in 2001, it has been subject to all sorts of claims, counterclaims, and myths. In fact, as Adam Rutherford explains, our genomes should be read not as instruction manuals, but as epic poems. DNA determines far less than we have been led to believe about us as individuals, but vastly more about us as a species. In this captivating journey through the expanding landscape of genetics, Adam Rutherford reveals what our genes now tell us about history, and what history tells us about our genes. From Neanderthals to murder, from redheads to race, dead kings to plague, evolution to epigenetics, this is a demystifying and illuminating new portrait of who we are and how we came to be."

    Instead, Guinan went to medical school and became a disease detective with the Centers for Disease Control and Prevention's Epidemic Intelligence Service. Selected to join India's Smallpox Eradication program, Guinan traveled to remote villages to isolate smallpox cases and then vaccinate all uninfected persons within a ten-mile radius. By May 1975, the World Health Organization declared Uttar Pradesh smallpox-free.During her barrier-breaking career, Dr. Guinan met arms-seeking Afghan insurgents in Pakistan and got caught in the crossfire between religious groups in Lebanon. She was one of the first medical detectives on the ground in San Francisco at the start of the AIDS crisis. And she served as an expert witness in a landmark decision that still protects HIV patients from workplace discrimination. Randy Shilts's best-selling book on the epidemic, And the Band Played On, features her AIDS work, as does the HBO movie of the same name.In Adventures of a Female Medical Detective, Guinan weaves together twelve vivid stories of her life in medicine, describing her individual experiences in controlling outbreaks, researching new diseases, and caring for patients the world over. Occasionally heartbreaking, sometimes hilarious, Guinan's account of her pathbreaking career will inspire public health students and future medical detectives--and give all readers insight into that part of the government exclusively devoted to protecting their health.

    Geoffrey Kurland was a busy man. His work as a Pediatric Pulmonologist, caring for children with lung diseases such as cystic fibrosis and asthma, led to long hours on the wards at the University of California, Davis Medical Center. At the same time, he was in the midst of training for the Western States Endurance Run, a grueling 100-mile long footrace across the wilderness of the Sierra Nevada Mountains. His long training runs, the responsibilities of patient care and teaching, and relationships attempting to replace his departed girlfriend occupied most of his life. Dr. Kurland’s ordered world is suddenly turned upside-down when he is diagnosed with Hairy Cell Leukemia, a rare blood cancer with a low survival rate. His work, his running, and his friendships are altered by his struggle to survive. He finds he must undergo many of the procedures he performed on his patients, must endure surgery and chemotherapy, and must relinquish control of his life to his physicians, surgeons, and his disease. He learns first-hand what cannot be taught in medical school about the consuming power of a chronic illness and its treatment.Confronting his own mortality, Dr. Kurland is now the patient while remaining a physician and runner. With the support of his physicians at the Mayo Clinic, the University of California, and the University of Pittsburgh, he resolves to continue to live his life despite his potentially fatal disease. He discovers his personal inner strengths as well as weaknesses as he struggles to confront his illness and regain some of the control he lost to it. Along his nearly two and a half year journey, we follow Dr. Kurland as he endures surgical procedures, chemotherapy, and life-threatening complications of his illness. He emerges into remission with new inner strength and understanding of what it means to be a doctor. He also finds that he is still a runner, with the same goal, to run the 100 miles across the Sierra Mountains.REVIEWS: “Taut, dramatic, and intensely real…Very well written.” --Oliver Sacks, the best selling author of SEEING VOICES and HALLUCINATIONS"[MY OWN MEDICINE] should be required reading for every medical professional. Kurland never asks for sympathy or pity. [...] What comes through powerfully is his humanity, which his own bout with illnesses has clearly enhanced, and from which both his patients and his readers will benefit." --THE NEW YORK TIMES"While training as a pediatric pulmonologist, Kurland told a patient, 'I know how you feel'; years later, when he was diagnosed with a rare form of leukemia, he discovered just how untrue this was. [...] The way in which serious illness alters one's sense of self and of life is compellingly expressed in this energetic, nervy narrative, as Kurland's illness and eventual recovery collide with a host of profound shifts—a big career move, the death of a colleague, an unravelling relationship with his girlfriend, and a deepening one with his parents." --THE NEW YORKER"MY OWN MEDICINE is rich in detail, enhanced by the author's skillful handling of the narrative...The book depicts a man who, faced with the painful reality of his own mortality, acknowledges his condition and gears himself to face the challenge." --PITTSBURGH POST-GAZETTE
“The story of Kurland’s battle with a disease that almost took his life is compelling and poignant. Unlike other chroniclers of illness, however, Kurland is a physician caring for critically ill children. Perhaps it is inevitable that his observations on life, death, and suffering should be so informed by his work. The result is a narrative that is both unique and deeply insightful.

    It is a place where life and death meet. A place where some families celebrate the most improbable of victories while others face the most devastating of losses. A place where what matters the most in this life is revealed. Trauma Room Two is just such a place. In this collection of short stories, Dr. Green takes the reader inside the hidden emotional landscape of emergency medicine. Based on fifteen years of experience as an ER physician, he reveals the profound moments that often occur in emergency rooms for patients, their families, and the staff that work there.

    The Sackler name adorns the walls of many storied institutions: Harvard, the Metropolitan Museum of Art, Oxford, the Louvre. They are one of the richest families in the world, known for their lavish donations to the arts and sciences. The source of the family fortune was vague, however, until it emerged that the Sacklers were responsible for making and marketing OxyContin, a blockbuster painkiller that was a catalyst for the opioid crisis.Empire of Pain is a masterpiece of narrative reporting and writing, exhaustively documented and ferociously compelling.

    Twelve astronauts made this greatest of all journeys and were indelibly marked by it, for better or for worse. Journalist Andrew Smith tracks down the nine surviving members of this elite group to find their answers to the question "Where do you go after you've been to the Moon?"A thrilling blend of history, reportage, and memoir, Moondust rekindles the hopeful excitement of an incandescent hour in America's past and captures the bittersweet heroism of those who risked everything to hurl themselves out of the known world -- and who were never again quite able to accept its familiar bounds.

    After high school she attended nursing school and then did something that would shatter her secure world for the rest of her life: in 1969, she joined the army and was shipped to Vietnam. When she arrived in Vietnam her idealistic view of the war vanished quickly. She worked long and arduous hours in cramped, ill-equipped, understaffed operating rooms. She saw friends die. Witnessing a war close-up, operating on soldiers and civilians whose injuries were catastrophic, she found the very foundations of her thinking changing daily. After one traumatic year, she came home, a Vietnam veteran. Coming home was nearly as devastating as the time she spent in Asia. Nothing was the same -- including Lynda herself. Viewed by many as a murderer instead of a healer, she felt isolated and angry. The anger turned to depression; like many other Vietnam veterans she suffered from delayed stress syndrome. Working in hospitals brought back chilling scenes of hopelessly wounded soldiers. A marriage ended in divorce. The war that was fought physically halfway around the world had become a personal, internal battle.Home before Morning is the story of a woman whose courage, stamina, and personal history make this a compelling autobiography. It is also the saga of others who went to war to aid the wounded and came back wounded -- physically and emotionally -- themselves. And, it is the true story of one person's triumphs: her understanding of, and coming to terms with, her destiny.

    The competition for training fellowship spots is intense. Hundreds of applicants from all over the world compete to be accepted into the Cardiovascular Disease Training Fellowship at Johns Hopkins. Only nine are chosen each year. This is the story of one of those fellows. In Alpha Docs, Daniel Muñoz, M.D., recounts his transformation from wide-eyed young medical student to caring, empathetic professional—providing a rare inside look into the day-to-day operations of one of the world’s most prestigious medical institutions. The training is arduous and often unforgiving, as Muñoz and his colleagues are schooled by a staff of brilliant and demanding physicians. How they learn the art and science of untangling cardiac mysteries, how they live up to the standards of an iconic institution, how they survive the pressures and relentlessly push themselves to reach the top ranks of American medicine, supplies the beating heart of this gripping narrative. Readers accompany Muñoz as he interacts with his mentors, diagnoses and treats patients, counsels worried family members, and struggles to stay awake for days and nights on end. Lives are saved—and sometimes lost. But the rewards are immediate and the incentives powerful. As Muñoz confides after helping to rescue one man from the throes of a heart attack: “I knew where I wanted to be: not watching but doing, on the side of the glass where I can help shape a patient’s fate. I would be a cardiologist.” A unique yet universal story about striving to be the best in a high-risk, high-impact field, Alpha Docs provides fresh perspective on the state of America’s healthcare system as it captures all the fulfillment and frustrations of life as a doctor in the twenty-first century.Praise for Alpha Docs“From the book’s beginning, Dr. Daniel Muñoz captivates readers with [the] life-changing story that decided his future. . . . Thoroughly allows readers to understand how cardiologists are made. Highly recommended.”—Medical Library Association “In simple, compelling prose, Alpha Docs captures the reader’s attention with gripping case histories, the astonishing breadth and complexity of top-notch medical training, and often wry, sometimes pointed character sketches of the attending physicians.”—Hopkins Medicine magazine “An insider’s view of the high-stakes world of cardiology, Alpha Docs offers a vivid and fast-paced exploration of the cauldron that creates doctors in the twenty-first century.”—Danielle Ofri, M.D., Ph.D., author of What Doctors Feel“[A] heartfelt medical-education memoir . . . a successful portrayal of just how hard it is, intellectually, emotionally, and physically, to train as a physician specialist.”—Booklist “This engaging book will interest those considering a career in medicine as well as readers who want to learn more about cardiology.

    It is the powerful story of four African-American female mathematicians at NASA who helped achieve some of the greatest moments in our space program. Now a major motion picture starring Taraji P. Henson, Octavia Spencer, Janelle Monae, Kirsten Dunst, and Kevin Costner.Before John Glenn orbited the earth, or Neil Armstrong walked on the moon, a group of dedicated female mathematicians known as “human computers” used pencils, slide rules, and adding machines to calculate the numbers that would launch rockets, and astronauts, into space.This book brings to life the stories of Dorothy Vaughan, Mary Jackson, Katherine Johnson, and Christine Darden, who lived through the Civil Rights era, the Space Race, the Cold War, and the movement for gender equality, and whose work forever changed the face of NASA and the country.