The Gene: An Intimate History


Siddhartha Mukherjee - 2016
    It intersects with Darwin’s theory of evolution, and collides with the horrors of Nazi eugenics in the 1940s. The gene transforms post-war biology. It reorganizes our understanding of sexuality, temperament, choice and free will. This is a story driven by human ingenuity and obsessive minds – from Charles Darwin and Gregor Mendel to Francis Crick, James Watson and Rosalind Franklin, and the thousands of scientists still working to understand the code of codes.This is an epic, moving history of a scientific idea coming to life, by the author of The Emperor of All Maladies. But woven through The Gene, like a red line, is also an intimate history – the story of Mukherjee’s own family and its recurring pattern of mental illness, reminding us that genetics is vitally relevant to everyday lives. These concerns reverberate even more urgently today as we learn to “read” and “write” the human genome – unleashing the potential to change the fates and identities of our children.Majestic in its ambition, and unflinching in its honesty, The Gene gives us a definitive account of the fundamental unit of heredity – and a vision of both humanity’s past and future.

Capitalism in the Web of Life: Ecology and the Accumulation of Capital


Jason W. Moore - 2015
    Climate. Food. Work. How are the crises of the twenty-first century connected? In Capitalism in the Web of Life, Jason W. Moore argues that the sources of today’s global turbulence have a common cause: capitalism as a way of organizing nature, including human nature. Drawing on environmentalist, feminist, and Marxist thought, Moore offers a groundbreaking new synthesis: capitalism as a “world-ecology” of wealth, power, and nature. Capitalism’s greatest strength—and the source of its problems—is its capacity to create Cheap Natures: labor, food, energy, and raw materials. That capacity is now in question. Rethinking capitalism through the pulsing and renewing dialectic of humanity-in-nature, Moore takes readers on a journey from the rise of capitalism to the modern mosaic of crisis. Capitalism in the Web of Life shows how the critique of capitalism-in-nature—rather than capitalism and nature—is key to understanding our predicament, and to pursuing the politics of liberation in the century ahead.

What Is Property?


Pierre-Joseph Proudhon - 1840
    

The World Without Us


Alan Weisman - 2007
    In this far-reaching narrative, Weisman explains how our massive infrastructure would collapse and finally vanish without human presence; which everyday items may become immortalized as fossils; how copper pipes and wiring would be crushed into mere seams of reddish rock; why some of our earliest buildings might be the last architecture left; and how plastic, bronze sculpture, radio waves, and some man-made molecules may be our most lasting gifts to the universe.The World Without Us reveals how, just days after humans disappear, floods in New York's subways would start eroding the city's foundations, and how, as the world's cities crumble, asphalt jungles would give way to real ones. It describes the distinct ways that organic and chemically treated farms would revert to wild, how billions more birds would flourish, and how cockroaches in unheated cities would perish without us. Drawing on the expertise of engineers, atmospheric scientists, art conservators, zoologists, oil refiners, marine biologists, astrophysicists, religious leaders from rabbis to the Dalai Lama, and paleontologists—who describe a prehuman world inhabited by megafauna like giant sloths that stood taller than mammoths—Weisman illustrates what the planet might be like today, if not for us.From places already devoid of humans (a last fragment of primeval European forest; the Korean DMZ; Chernobyl), Weisman reveals Earth's tremendous capacity for self-healing. As he shows which human devastations are indelible, and which examples of our highest art and culture would endure longest, Weisman's narrative ultimately drives toward a radical but persuasive solution that needn't depend on our demise. It is narrative nonfiction at its finest, and in posing an irresistible concept with both gravity and a highly readable touch, it looks deeply at our effects on the planet in a way that no other book has.

Evolution in Four Dimensions: Genetic, Epigenetic, Behavioral, and Symbolic Variation in the History of Life


Eva Jablonka - 2005
    New findings in molecular biology challenge the gene-centered version of Darwinian theory according to which adaptation occurs only through natural selection of chance DNA variations. In Evolution in Four Dimensions, Eva Jablonka and Marion Lamb argue that there is more to heredity than genes. They trace four dimensions in evolution -- four inheritance systems that play a role in evolution: genetic, epigenetic (or non-DNA cellular transmission of traits), behavioral, and symbolic (transmission through language and other forms of symbolic communication). These systems, they argue, can all provide variations on which natural selection can act. Evolution in Four Dimensions offers a richer, more complex view of evolution than the gene-based, one-dimensional view held by many today. The new synthesis advanced by Jablonka and Lamb makes clear that induced and acquired changes also play a role in evolution. After discussing each of the four inheritance systems in detail, Jablonka and Lamb put Humpty Dumpty together again by showing how all of these systems interact. They consider how each may have originated and guided evolutionary history and they discuss the social and philosophical implications of the four-dimensional view of evolution. Each chapter ends with a dialogue in which the authors engage the contrarieties of the fictional (and skeptical) I.M., or Ifcha Mistabra -- Aramaic for the opposite conjecture -- refining their arguments against I.M.'s vigorous counterarguments. The lucid and accessible text is accompanied by artist-physician Anna Zeligowski's lively drawings, which humorously and effectively illustrate the authors' points.

The Culture of Narcissism: American Life in An Age of Diminishing Expectations


Christopher Lasch - 1978
    Lasch’s identification of narcissism as not only an individual ailment but also a burgeoning social epidemic was groundbreaking. His diagnosis of American culture is even more relevant today, predicting the limitless expansion of the anxious and grasping narcissistic self into every part of American life.The Culture of Narcissism offers an astute and urgent analysis of what we need to know in these troubled times.

Emergence: The Connected Lives of Ants, Brains, Cities, and Software


Steven Johnson - 2001
    Explaining why the whole is sometimes smarter than the sum of its parts, Johnson presents surprising examples of feedback, self-organization, and adaptive learning. How does a lively neighborhood evolve out of a disconnected group of shopkeepers, bartenders, and real estate developers? How does a media event take on a life of its own? How will new software programs create an intelligent World Wide Web? In the coming years, the power of self-organization -- coupled with the connective technology of the Internet -- will usher in a revolution every bit as significant as the introduction of electricity. Provocative and engaging, Emergence puts you on the front lines of this exciting upheaval in science and thought.

Regenesis: How Synthetic Biology Will Reinvent Nature and Ourselves


George M. Church - 2012
    Building a house would entail no more work than planting a seed in the ground. These scenarios may seem far-fetched, but pioneering geneticist George Church and science writer Ed Regis show that synthetic biology is bringing us ever closer to making such visions a reality. In Regenesis, Church and Regis explore the possibilities—and perils—of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. Until now, nature has been the exclusive arbiter of life, death, and evolution; with synthetic biology, we now have the potential to write our own biological future. Indeed, as Church and Regis show, it even enables us to revisit crucial points in the evolution of life and, through synthetic biological techniques, choose different paths from those nature originally took. Such exploits will involve far more than just microbial tinkering. Full-blown genomic engineering will make possible incredible feats, from resurrecting woolly mammoths and other extinct organisms to creating mirror life forms with a molecular structure the opposite of our own. These technologies—far from the out-of-control nightmare depicted in science fiction—have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span. A breathtaking look at the potential of this world-changing technology, Regenesis is nothing less than a guide to the future of life.

The Anatomy of Violence: The Biological Roots of Crime


Adrian Raine - 2013
    In The Anatomy of Violence, Raine dissects the criminal mind with a fascinating, readable, and far-reaching scientific journey into the body of evidence that reveals the brain to be a key culprit in crime causation.  Raine documents from genetic research that the seeds of sin are sown early in life, giving rise to abnormal physiological functioning that cultivates crime. Drawing on classical case studies of well-known killers in history—including Richard Speck, Ted Kaczynski, and Henry Lee Lucas—Raine illustrates how impairments to brain areas controlling our ability to experience fear, make good decisions, and feel guilt predispose us to violence. He contends that killers can actually be coldhearted: something as simple as a low resting heart rate can give rise to violence. But arguing that biology is not destiny, he also sketches out provocative new biosocial treatment approaches that can change the brain and prevent violence.  Finally, Raine tackles the thorny legal and ethical dilemmas posed by his research, visualizing a futuristic brave new world where our increasing ability to identify violent offenders early in life might shape crime-prevention policies, for good and bad. Will we sacrifice our notions of privacy and civil rights to identify children as potential killers in the hopes of helping both offenders and victims? How should we punish individuals with little to no control over their violent behavior? And should parenting require a license? The Anatomy of Violence offers a revolutionary appraisal of our understanding of criminal offending, while also raising provocative questions that challenge our core human values of free will, responsibility, and punishment.From the Hardcover edition.

Mutants: On Genetic Variety and the Human Body


Armand Marie Leroi - 2003
    This elegant, humane, and engaging book "captures what we know of the development of what makes us human" (Nature).Visit Armand Marie Leroi on the web: http: //armandleroi.com/index.htmlStepping effortlessly from myth to cutting-edge science,

Industrial Society and Its Future


Theodore J. Kaczynski - 1995
    They have greatly increased the life-expectancy of those of us who live in "advanced" countries, but they have destabilized society, have made life unfulfilling, have subjected human beings to indignities, have led to widespread psychological suffering (in the Third World to physical suffering as well) and have inflicted severe damage on the natural world. The continued development of technology will worsen the situation. It will certainly subject human beings to greater indignities and inflict greater damage on the natural world, it will probably lead to greater social disruption and psychological suffering, and it may lead to increased physical suffering even in "advanced" countries.

Mendel in the Kitchen: A Scientist's View of Genetically Modified Foods


Nina V. Fedoroff - 2004
    Mendel in the Kitchen provides a clear and balanced picture of this tangled, tricky (and very timely) topic.Any farmer you talk to could tell you that we've been playing with the genetic makeup of our food for millennia, carefully coaxing nature to do our bidding. The practice officially dates back to Gregor Mendel--who was not a renowned scientist, but a 19th century Augustinian monk. Mendel spent many hours toiling in his garden, testing and cultivating more than 28,000 pea plants, selectively determining very specific characteristics of the peas that were produced, ultimately giving birth to the idea of heredity--and the now very common practice of artificially modifying our food.But as science takes the helm, steering common field practices into the laboratory, the world is now keenly aware of how adept we have become at tinkering with nature--which in turn has produced a variety of questions. Are genetically modified foods really safe? Will the foods ultimately make us sick, perhaps in ways we can't even imagine? Isn't it genuinely dangerous to change the nature of nature itself?Nina Fedoroff, a leading geneticist and recognized expert in biotechnology, answers these questions, and more. Addressing the fear and mistrust that is rapidly spreading, Federoff and her co-author, science writer Nancy Brown, weave a narrative rich in history, technology, and science to dispel myths and misunderstandings.In the end, Fedoroff arues, plant biotechnology can help us to become better stewards of the earth while permitting us to feed ourselves and generations of children to come. Indeed, this new approach to agriculture holds the promise of being the most environmentally conservative way to increase our food supply.

The Mismeasure of Man


Stephen Jay Gould - 1982
    Gould's brilliant, funny, engaging prose dissects the motivations behind those who would judge intelligence, and hence worth, by cranial size, convolutions, or score on extremely narrow tests. How did scientists decide that intelligence was unipolar and quantifiable? Why did the standard keep changing over time? Gould's answer is clear and simple: power maintains itself. European men of the 19th century, even before Darwin, saw themselves as the pinnacle of creation and sought to prove this assertion through hard measurement. When one measure was found to place members of some "inferior" group such as women or Southeast Asians over the supposedly rightful champions, it would be discarded and replaced with a new, more comfortable measure. The 20th-century obsession with numbers led to the institutionalization of IQ testing and subsequent assignment to work (and rewards) commensurate with the score, shown by Gould to be not simply misguided--for surely intelligence is multifactorial--but also regressive, creating a feedback loop rewarding the rich and powerful. The revised edition includes a scathing critique of Herrnstein and Murray's The Bell Curve, taking them to task for rehashing old arguments to exploit a new political wave of uncaring belt tightening. It might not make you any smarter, but The Mismeasure of Man will certainly make you think.--Rob LightnerThis edition is revised and expanded, with a new introduction

Life on the Edge: The Coming of Age of Quantum Biology


Johnjoe McFadden - 2014
    Life remains the only way to make life. Are we still missing a vital ingredient in its creation?      Like Richard Dawkins' The Selfish Gene, which provided a new perspective on how evolution works, Life on the Edge alters our understanding of our world's fundamental dynamics. Bringing together first-hand experience at the cutting edge of science with unparalleled gifts of explanation, Jim Al-Khalili and Johnjoe Macfadden reveal that missing ingredient to be quantum mechanics; the phenomena that lie at the heart of this most mysterious of sciences. Drawing on recent ground-breaking experiments around the world, each chapter in Life on the Edge engages by illustrating one of life's puzzles: How do migrating birds know where to go? How do we really smell the scent of a rose? How do our genes copy themselves with such precision? Life on the Edge accessibly reveals how quantum mechanics can answer these probing questions of the universe. Guiding the reader through the rapidly unfolding discoveries of the last few years, Al-Khalili and McFadden communicate the excitement of the explosive new field of quantum biology and its potentially revolutionary applications, while offering insights into the biggest puzzle of all: what is life? As they brilliantly demonstrate in these groundbreaking pages, life exists on the quantum edge.

The Conscious Mind: In Search of a Fundamental Theory


David J. Chalmers - 1996
    Dennett, Gerald Edelman, and Roger Penrose, all firing volleys in what has come to be called the consciousness wars. Now, in The Conscious Mind, philosopher David J. Chalmers offers a cogent analysis of this heated debate as he unveils a major new theory of consciousness, one that rejects the prevailing reductionist trend of science, while offering provocative insights into the relationship between mind and brain.Writing in a rigorous, thought-provoking style, the author takes us on a far-reaching tour through the philosophical ramifications of consciousness. Chalmers convincingly reveals how contemporary cognitive science and neurobiology have failed to explain how and why mental events emerge from physiological occurrences in the brain. He proposes instead that conscious experience must be understood in an entirely new light--as an irreducible entity (similar to such physical properties as time, mass, and space) that exists at a fundamental level and cannot be understood as the sum of its parts. And after suggesting some intriguing possibilities about the structure and laws of conscious experience, he details how his unique reinterpretation of the mind could be the focus of a new science. Throughout the book, Chalmers provides fascinating thought experiments that trenchantly illustrate his ideas. For example, in exploring the notion that consciousness could be experienced by machines as well as humans, Chalmers asks us to imagine a thinking brain in which neurons are slowly replaced by silicon chips that precisely duplicate their functions--as the neurons are replaced, will consciousness gradually fade away? The book also features thoughtful discussions of how the author's theories might be practically applied to subjects as diverse as artificial intelligence and the interpretation of quantum mechanics.All of us have pondered the nature and meaning of consciousness. Engaging and penetrating, The Conscious Mind adds a fresh new perspective to the subject that is sure to spark debate about our understanding of the mind for years to come.