At just two years old, Nic experienced a searing pain that signaled the awakening of a new and deadly disease, one that would hurl Nic and his family up against the limits of modern medicine. For years, through false starts and failed cures, Nic holds on to life, buoyed up by his mother’s fierce drive to get him the care he needs. But when even the world’s experts are stumped by Nic’s illness, his doctors come up with a radical, long-shot plan: a step into the unknown. The next major scientific frontier, following the completion of the Human Genome Project, was to figure out how to use our new knowledge to save lives—to bring genomic or personalized medicine into reality. It’s a quest that is undertaken by researchers around the world. But it is only when geneticist Howard Jacob hears about young Nic that the finish line finally comes into sight: It’s no longer a race to make history. It’s a race to save this boy’s life. One in a Billion is an unforgettable tale of the lives that converged to launch a medical revolution. As pioneering geneticist Mary-Claire King pronounced upon learning Nic’s story: “It was as if one had heard about Case Zero of AIDS and the cure, all at once.”

    Master clinician Karen J. Maroda adds an important dimension to the psychodynamic literature by exploring the role of both clients' and therapists' emotional experiences in the process of therapy. The book discusses how to become more attuned to one's own experience of a client; offer direct feedback and self-disclosure in the service of treatment goals; and manage intense feelings and conflict in the relationship. Specific techniques are illustrated with vivid case examples. Maroda clearly distinguishes between therapeutic and nontherapeutic ways to work with emotion in this candid and instructive guide.

    Drawing on over thirty years of experience as a psychotherapist, analyst, and teacher, Dr. Gaylin addresses the fundamentals of the therapeutic process: How does therapy work? Can "talking" truly precipitate a change in behavior? Why do therapists rely so heavily on childhood experiences? Does the past really affect the present? Gaylin speaks plainly but profoundly about the art of therapy, what the roles of the patient and therapist should be, and what it takes, on the part of each, for a patient to get better. The result is an enlightening tour through one of the most misunderstood sciences of our time. As insurance companies limit the number of therapy sessions they will cover and people look for quick-fix "cures" for their psychological ailments, Dr. Gaylin explains the importance of long-term therapy. This book has a natural audience of people in therapy. Current estimates put this number at 15 million.

    An exploration of technology used by ancient civilizations and the support it provides for certain biblical interpretations.

    The memoir brings to life Harry's past experiences and feelings, from his torrid time at school to the peaceful and meaningful moments when he is alone with a book, writing or creating YouTube videos.Eloquent and insightful, The PDA Paradox will bring readers to shock, laughter and tears through its overwhelming honesty. It is a turbulent memoir, but it ends with hope and a positive outlook to the future.

    This book covers all the important aspects of plant tissue culture viz. nutrition media, micropropagation, organ culture, cell suspension culture, haploid culture, protoplast isolation and fusion, secondary metabolite production, somaclonal variation and cryopreservation. For good understanding of recombinant DNA technology, chapters on genetic material, organization of DNA in the genome and basic techniques involved in recombinant DNA technology have been added. Different aspects on rDNA technology covered gene cloning, isolation of plant genes, transposons and gene tagging, in vitro mutagenesis, PCR, molecular markers and marker assisted selection, gene transfer methods, chloroplast and mitochondrion DNA transformation, genomics and bioinformatics. Genomics covers functional and structural genomics, proteomics, metabolomics, sequencing status of different organisms and DNA chip technology. Application of biotechnology has been discussed as transgenics in crop improvement and impact of recombinant DNA technology mainly in relation to biotech crops.

    Phages are also being used to detect and remove pathogens from our food supplies, both plant and animal. Also exciting is the use of phages as vehicles to delivery DNA vaccines, often directly to mammalian immune system cells. Recent work also suggests possible antitumor effects of phages. We stand on the edge of a whole new world of exploration and applications of microbiology. For over 20 years, and through five editions, Black's Microbiology: Principles and Explorations has captured students' imaginations. Her enthusiasm, passion, and knack for memorable stories and anecdotes bring the study of microbiology to life in a way few other texts can match. Now updated to reflect the latest topics in the field (e.g., SARS, bioterrorism, GMO's, geomicrobiology) and accompanied by state-of-the-art animations of key concepts, this new edition is sure to help inspire a new generation of enthusiasts for the dynamic science of microbiology. Critical Acclaim "I continue to find Black's text an excellent contribution to undergraduate Microbiology education." --Karen Messley, Rock Valley College "I like the conversational and informal style Black adopts throughout the book. This is a book, which could very well engage even the most reluctant student. It is comprehensive, nicely detailed, and incorporates many aids to teaching and learning..."--Iris Cook, Westchester CC "[The text] is a wonderful introduction into the world of microorganisms for students from a wide variety of backgrounds."--Jeff G. Leid, Northern Arizona University ..".I have found it [the book] accurate to a fault, brilliant at getting students motivated and interested in microbiology, and a great practical training book."--Gerard O'Donovan, University of North Texas Also available Laboratory Exercises in Microbiology, 2nd Edition Robert A. Pollack, et al. ISBN: 0-471-42082-4, 264 pages, paper, (c)2005 Written specifically for allied health students, this lab manual presents a variety of highly engaging activities and experiments that convey the basic concepts of microbiology.

    Tracing our culinary customs from the Stone Age to the stovetop range, he illuminates our complex and often contradictory eating habits, and suggests that perhaps we are what we eat.

    Slater, career-oriented and willfully autonomous, charts her own personal journey and decision-making process, starting with a list of the pros and cons, about having a child. The cons are many, the pros only one: “learning a new kind of love.” But what will that love look like? How does one reconcile the needs of the self with the demands of others? How do couples go from the dyad that is a marriage to the triad that is a family? And how can Slater adjust to losing precious control of her own carefully developed life?Slater’s complex biological and psychological history also lies at the core of this unique and yet strikingly universal story. One of the first people ever to take Prozac, she chronicles the impossibly conflicting advice regarding pregnancy and antidepressants, and explains the rationale behind her eventual decision to stop taking the medication during her first trimester. This is Slater’s first encounter with self-sacrifice, and for her a crossroad at which modern medicine and basic human love meet. Love Works Like This is a richly written book by “an enormously poetic and ebullient writer” (Elle magazine), an author who writes with “beauty and bravery” (Los Angeles Times Book Review) about falling in love, about growing into the ability to put someone else’s life ahead of your own, and about the rich rewards we can draw from the courage to exchange one kind of happy life for another.

    While maintaining the hallmark features of previous editions, the Fourth Edition has been completely updated. It includes new Key Concepts at the beginning of each chapter and annotated further reading at the conclusion of each chapter, to help readers navigate the wealth of information in this subject.The text has been restructured so genomic technologies are integrated throughout, and next generation sequencing is included. Genetic testing, screening, approaches to therapy, personalized medicine, and disease models have been brought together in one section. Coverage of cell biology including stem cells and cell therapy, studying gene function and structure, comparative genomics, model organisms, noncoding RNAs and their functions, and epigenetics have all been expanded.

    Easy to navigate and easy to use, the Prescriber's Guide combines evidence-based information with clinically informed guidance to support clinicians in making the most effective prescribing decisions for the good of their patients. With coverage of twelve brand-new drugs including antidepressants, antipsychotics, hypnotics, nonstimulants for ADHD, and medical foods and incorporating information on the newest indications, new formulations, new recommendations, and new safety data, this edition continues to provide the essential practical support required by anyone prescribing in the field of mental health."

    MCT developer Adrian Wells shows that much psychological distress results from how a person responds to negative thoughts and beliefs—for example, by ruminating or worrying—rather than the content of those thoughts. He presents practical techniques and specific protocols for addressing metacognitive processes to effectively treat generalized anxiety disorder, obsessive–compulsive disorder, posttraumatic stress disorder, and major depression. Special features include reproducible treatment plans and assessment and case formulation tools, plus a wealth of illustrative case material.

    Lost Marbles straddles the line between self-help and memoir detailing real-life experiences that drive tips that work when life includes a mental illness. Improve your life or the life of a person you love with informative and experienced new takes on: Thinking like a person with bipolar or depression What the elevated mood of bipolar disorder feels like Medication issues, including detailed information on choosing (or not choosing) a specific medication The realities of suicide and suicide attempts How to live better with a serious mental illness How dealing with mental illness encourages a form of wisdom Called a book that will "certainly save lives," whether you have a mental illness or you love someone who does, Lost Marbles will help you fathom the seemingly-impossible world of bipolar or depressive disorder and arm you with the tools to improve quality of life.

    It is employed in mental health settings, medical centers, and correctional programs, and is frequently admitted as evidence in legal proceedings. In addition, use of the MMPI-2 in the process of screening applicants for jobs that involve public trust and safety is spreading rapidly.The fourth edition of MMPI-2: Assessing Personality and Psychopathology describes effective uses of the MMPI-2 and explains how to accurately interpret test results. Current and comprehensive, it presents detailed instructions for administering, scoring, and coding the MMPI-2. It also discusses the most recent interpretations of the test's validity, clinical content, and supplementary scales; illustrating points with case studies and examples. In addition, the book covers two new sets of scales: the Restructured Clinical (RC) scales, which help focus the interpretation of the original clinical scales; and the Personality Psychopathology 5 (PSY-5) scales, which assess major dimensions of normal and abnormal personality.MMPI-2: Assessing Personality and Psychopathology, Fourth Edition, is ideal for graduate courses in psychological assessment and an indispensable guide for researchers and clinicians working in personality assessment.Features-Incorporates new information from recent empirical research studies-Covers the latest developments in supplementary scales-Discusses using the MMPI-2 with such diverse population groups as older adults, ethnic minorities, medical patients, and prisoners-Includes the latest information on computerized administration, scoring, and interpretation of test results-Provides expanded technical material

    In existence for some hundred million years, it was discovered only recently. Exploring its evolution, its daily existence, and its journey from ticks to mice to deer to humans, Karlen lucidly examines the life and world of this recently prominent germ. He also describes how it attacks the human body, and how by changing the environment, people are now much more likely to come into contact with it. Charming and thorough and smart, this book is a wonderfully written biography of your not so typical biographical subject.