A biography of the Nobel Prize-winning scientist explains her work in genetics and traces her long unheralded career as a research scientist.

    Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with - and perished from - for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. From the Persian Queen Atossa, whose Greek slave cut off her malignant breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee’s own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive—and to increase our understanding of this iconic disease. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

    For decades after the structure of DNA was identified, scientists focused purely on genes, the regions of the genome that contain codes for the production of proteins. Other regions - 98% of the human genome - were dismissed as 'junk'. But in recent years researchers have discovered that variations in this 'junk' DNA underlie many previously intractable diseases, and they can now generate new approaches to tackling them. Nessa Carey explores, for the first time for a general audience, the incredible story behind a controversy that has generated unusually vituperative public exchanges between scientists. She shows how junk DNA plays an important role in areas as diverse as genetic diseases, viral infections, sex determination in mammals, human biological complexity, disease treatments, even evolution itself - and reveals how we are only now truly unlocking its secrets, more than half a century after Crick and Watson won their Nobel prize for the discovery of the structure of DNA in 1962.

    Students around the world are taught about his theories and equations with E=mc2 undoubtedly being the most famous.However, there was more to this man than simply being a genius or the original prototype of the mad professor. Instead, this was a man that was dedicated to not only his profession, but also the concept of pacifism, something that most people are unaware of.Albert Einstein went from a late developing child to running away from school to almost failing university and instead turned himself into one of the greatest minds that the world has ever seen. This is his story, a story of how a child taught himself calculus and geometry and was then not afraid to challenge concepts of how the world worked that had been unchanged for centuries. This was a man who stood up for what he believed in even when the world appeared to be against him.The story of Albert Einstein is about more than just mathematical equations. The story is about a man who beat the odds and became world famous in the unlikely world of physics and the universe.

    Focusing on four specific examples — corn, silkworms, domestic cats, and apples — she traces the histories of species that have been fundamentally altered over the centuries by the whims and needs of people.

    The first abnormal psychology book to present a thoroughly integrated multicultural perspective--based on the authors' view that cross-cultural comparisons can greatly enhance the understanding of disorders--the text provides extensive coverage and integration of multicultural models, explanations, and concepts. The book also helps you gain an understanding of abnormal behavior as scientific and clinical endeavors, while providing insight into the tools that mental health professionals use to study and treat disorders.

    

    Download issues at no extra cost from Archived Items. The Economist is the premier source for the analysis of world business and current affairs, providing authoritative insight and opinion on international news, world politics, business, finance, science and technology, as well as overviews of cultural trends and regular Special reports on industries and countries. Established in 1843 to campaign against the protectionist corn laws, The Economist remains, in the second half of its second century, true to the liberal principles of its founder. James Wilson, a hat maker from the small Scottish town of Hawick, believed in free trade, internationalism and minimum interference by government, especially in the affairs of the market. The Economist also takes a fiercely independent stance on social issues, from gay marriage to the legalisation of drugs, but its main service to its readers is as a global newspaper: To uncover new ideas from all around the world. The Kindle Edition of The Economist contains all of the articles and graphics found in the print edition, but will not include all photos. For your convenience, issues are auto-delivered wirelessly to your Kindle each Friday at the same time the print edition hits the newsstand.

     In the gambling fraternity, Harry Findlay has earned legendary status. He has been skint dozens of times, won over £20 million and spent just as much. But he will not change. Fearless and formidable, bullish and bombastic, there is no one in the gambling game who can match Harry’s style and seismic impact. When he first ran a betting slip through his fingers as a 16-year-old, Harry said he had been handed the keys to the Magic Kingdom. Gambling has taken him all around the globe, enjoying five-star travel and a gourmet’s indulgence at the world’s biggest sporting events. In his much-awaited book, Harry recounts the mind-boggling tales behind the thousand and million pound multi-sport bets that will make ordinary punters shudder – including the day he wagered £2.5 million on a rugby match. It is a remarkable life story of ups and downs. Aged 21 years old, he served nearly a year in some of Her Majesty’s toughest jails. Who’d have thought he would go on to own Big Fella Thanks, winner of the Derby at Clonmel and the most famous dog to come out of Ireland – and be part owner of the legendary racehorse Denman, who carried his colours to Gold Cup glory. Harry’s subsequent controversial disqualification from racing destroyed him, despite the ruling being overturned on appeal. Most fascinating of all, Harry tells how he has survived and continues to work his magic in the gambling world, and still believes in his own special talent to read sports events and to continue to stay one step ahead of the internet companies that flood our minds with the temptation to risk so much. Harry Findlay: Gambling For Life reflects one man’s extraordinary passion for gambling. How he cannot live without it. And how he knows that, even if he loses all of his money, he can never be a loser.

    Its unique 'Frontiers' chapters cover materials science, nanotechnology, catalysis, and biological inorganic chemistry, and have been fully updated to reflect advances in these key areas of contemporary research and industrial application.

    In The Violinist's Thumb, he explores the wonders of the magical building block of life: DNA.There are genes to explain crazy cat ladies, why other people have no fingerprints, and why some people survive nuclear bombs. Genes illuminate everything from JFK's bronze skin (it wasn't a tan) to Einstein's genius. They prove that Neanderthals and humans bred thousands of years more recently than any of us would feel comfortable thinking. They can even allow some people, because of the exceptional flexibility of their thumbs and fingers, to become truly singular violinists. Kean's vibrant storytelling makes science entertaining, explaining human history and whimsy while showing how DNA will influence our species' future.

    Time-saving study tools help readers arrive at a complete understanding of human anatomy. KEY TOPICS: An Introduction to Anatomy, The Cell, Tissues and Early Embryology, The Integumentary System, The Skeletal System: Osseous Tissue and Skeletal Structure, The Skeletal System: Axial Division, The Skeletal System: Appendicular Division, The Skeletal System: Articulations, The Muscular System: Skeletal Muscle Tissue and Muscle Organization, The Muscular System: Axial Musculature, The Muscular System: Appendicular Musculature, Surface Anatomy and Cross-Sectional Anatomy, The Nervous System: Neural Tissue, The Nervous System: The Spinal Cord and Spinal Nerves, The Nervous System: The Brain and Cranial Nerves, The Nervous System: Pathways And Higher-Order Functions, The Nervous System:  Autonomic Division, The Nervous System: General and Special Senses, The Endocrine System, The Cardiovascular System: Blood, The Cardiovascular System: The Heart, The Cardiovascular System: Vessels and Circulation, The Lymphoid System, The Respiratory System, The Digestive System, The Urinary System, The Reproductive System, The Reproductive System: Embryology and HumanDevelopment. MARKET: For all readers interested in human anatomy.

    Evo Devo Evolutionary Developmental Biology is the new science that has finally cracked open the box. Within the pages of his rich and riveting book, Sean B. Carroll explains how we are discovering that complex life is ironically much simpler than anyone ever expected.

    In The Anatomy of Violence, Raine dissects the criminal mind with a fascinating, readable, and far-reaching scientific journey into the body of evidence that reveals the brain to be a key culprit in crime causation.  Raine documents from genetic research that the seeds of sin are sown early in life, giving rise to abnormal physiological functioning that cultivates crime. Drawing on classical case studies of well-known killers in history—including Richard Speck, Ted Kaczynski, and Henry Lee Lucas—Raine illustrates how impairments to brain areas controlling our ability to experience fear, make good decisions, and feel guilt predispose us to violence. He contends that killers can actually be coldhearted: something as simple as a low resting heart rate can give rise to violence. But arguing that biology is not destiny, he also sketches out provocative new biosocial treatment approaches that can change the brain and prevent violence.  Finally, Raine tackles the thorny legal and ethical dilemmas posed by his research, visualizing a futuristic brave new world where our increasing ability to identify violent offenders early in life might shape crime-prevention policies, for good and bad. Will we sacrifice our notions of privacy and civil rights to identify children as potential killers in the hopes of helping both offenders and victims? How should we punish individuals with little to no control over their violent behavior? And should parenting require a license? The Anatomy of Violence offers a revolutionary appraisal of our understanding of criminal offending, while also raising provocative questions that challenge our core human values of free will, responsibility, and punishment.From the Hardcover edition.

    These areas of knowledge have converged into a modern theory of epidemiology that has been slow to penetrate into textbooks, particularly at the introductory level. Epidemiology: An Introduction closes the gap. It begins with a brief, lucid discussion of causal thinking and causal inference and then takes the reader through the elements of epidemiology, focusing on the measures of disease occurrence and causal effects. With these building blocks in place, the reader learns how to design, analyze and interpret problems that epidemiologists face, including confounding, the role of chance, and the exploration of interactions. All these topics are layered on the foundation of basic principles presented in simple language, with numerous examples and questions for further thought.